KEGG T00262: M5005

Streptococcus pyogenes MGAS5005 (serotype M1): M5005_Spy1073

Entry

M5005_Spy1073     CDS       T00262

Symbol

dltA

Name

(GenBank) D-alanine-activating enzyme

K03367

D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]

Organism

spz Streptococcus pyogenes MGAS5005 (serotype M1)

Pathway

spz00470

D-Amino acid metabolism

spz00552

Teichoic acid biosynthesis

spz01100

Metabolic pathways

spz01503

Cationic antimicrobial peptide (CAMP) resistance

spz02020

Two-component system

Brite

KEGG Orthology (KO) [BR:spz00001]
09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    M5005_Spy1073 (dltA)
  09107 Glycan biosynthesis and metabolism
   00552 Teichoic acid biosynthesis
    M5005_Spy1073 (dltA)
09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    M5005_Spy1073 (dltA)
09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01503 Cationic antimicrobial peptide (CAMP) resistance
    M5005_Spy1073 (dltA)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:spz01504]
    M5005_Spy1073 (dltA)
Enzymes [BR:spz01000]
6. Ligases
  6.1  Forming carbon-oxygen bonds
   6.1.1  Ligases forming aminoacyl-tRNA and related compounds
    6.1.1.13  D-alanine---poly(phosphoribitol) ligase
     M5005_Spy1073 (dltA)
Antimicrobial resistance genes [BR:spz01504]
Gene sets
  CAMP resistance modules
   Cationic antimicrobial peptide (CAMP) resistance, dltABCD operon [MD:M00725]
    M5005_Spy1073 (dltA)

SSDB

Motif

Pfam:

AMP-binding AMP-binding_C

Other DBs

NCBI-ProteinID:

AAZ51691

UniProt:

Q99ZA6

Structure

LinkDB

Position

complement(1045650..1047188)

AA seq 512 aa
MIKDMIDSIEQFAQTQADFPVYDCLGERRTYGQLKRDSDSIAAFIDSLALLAKSPVLVFG
AQTYNMLATFVALTKSGHAYIPVDVHSAPERILAIIEIAKPSLIIAIEEFPLTIEGISLV
SLSEIESAKLAEMPYERTHSVKGDDNYYIIFTSGTTGQPKGVQISHDNLLSFTNWMIEDA
AFDVPKQPQMLAQPPYSFDLSVMYWAPTLALGGTLFALPKELVADFKQLFTTIAQLPVGI
WTSTPSFADMAMLSDDFCQAKMPALTHFYFDGEELTVSTARKLFERFPSAKIINAYGPTE
ATVALSAIEITREMVDNYTRLPIGYPKPDSPTYIIDEDGKELSSGEQGEIIVTGPAVSKG
YLNNPEKTAEAFFTFKGQPAYHTGDIGSLTEDNILLYGGRLDFQIKYAGYRIELEDVSQQ
LNQSPMVASAVAVPRYNKEHKVQNLLAYIVVKDGVKERFDRELELTKAIKASVKDHMMSY
MMPSKFLYRDSLPLTPNGKIDIKTLINEVNNR

NT seq 1539 nt +upstreamnt +downstreamnt
atgattaaggatatgattgacagtattgagcagtttgctcagacacaggctgattttcca
gtttatgattgtttaggggaacgccgcacttacggacaactcaaaagagattctgatagc
attgctgcatttatagatagcttagctttactggcaaaatctccagttttggtttttggg
gcgcaaacttataatatgttagctacttttgtagctttaaccaaatctggtcatgcctat
atcccagtagatgtgcattcagcaccagaacgtattttagcgattattgagattgcaaag
cccagtttaatcattgctattgaggaattccctcttactattgaagggatttcccttgtc
tcactatcagagattgagtcagcaaaattagcagaaatgccctatgagcgaacacattct
gttaaaggagatgataattattacattattttcacctctggaacaacgggccaaccaaaa
ggggtgcaaatttcacatgacaatcttttgagctttaccaactggatgatcgaagatgca
gcatttgatgtacctaaacagccacaaatgctggcgcagccaccctattcctttgacctt
tctgtcatgtactgggcacctaccttggctttaggtggaaccttatttgcacttccaaaa
gaattggtggcagactttaaacagttatttacaacgattgcgcaacttccagttggcatt
tggacatcgactccttcatttgctgatatggccatgcttagcgatgatttttgccaggct
aagatgccagctttaacgcatttttattttgatggcgaagaattaaccgtttctacggct
cgaaaactctttgaacgtttcccgagtgccaagattatcaatgcctatggaccaacagaa
gcgactgtagccttatccgctattgaaattaccagagaaatggtggataattatacccgc
ttgccgattggctaccccaaaccagattctccgacctatattattgatgaagatggtaag
gagttatcttcaggggagcagggtgaaattattgttacagggcctgctgtgtcaaaaggt
tacctcaacaatcctgagaaaaccgcagaagctttctttacttttaaaggacagcctgct
tatcatacaggggacattggctcactgacagaagataatattttgttgtatggtgggcgt
ttggattttcagattaaatatgctggttatcgtattgaactagaagatgtttcccaacag
ttgaatcaatcaccaatggtagcatcggctgtggctgttccaaggtacaataaagaacat
aaggttcaaaatctcttggcctatatcgttgtcaaagatggggttaaagagcgttttgat
agggaattggagttaaccaaagctatcaaagcctctgttaaggatcatatgatgagttat
atgatgccttctaagtttctttatcgagatagtctaccattaactccaaatggtaagata
gatattaaaactttgattaatgaggtcaataaccgatga

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