KEGG   PATHWAY: ath00630
Entry
ath00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Arabidopsis thaliana (thale cress)
Class
Metabolism; Carbohydrate metabolism
Pathway map
ath00630  Glyoxylate and dicarboxylate metabolism
ath00630

Module
ath_M00012  Glyoxylate cycle [PATH:ath00630]
ath_M00532  Photorespiration [PATH:ath00630]
ath_M00621  Glycine cleavage system [PATH:ath00630]
Other DBs
GO: 0046487 0043648
Organism
Arabidopsis thaliana (thale cress) [GN:ath]
Gene
AT3G21720  ICL; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
AT5G36880  ACS; acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
AT3G16910  AAE7; acyl-activating enzyme 7 [KO:K01913] [EC:6.2.1.1 6.2.1.2]
AT5G03860  MLS; malate synthase [KO:K01638] [EC:2.3.3.9]
AT1G04410  c-NAD-MDH1; Lactate/malate dehydrogenase family protein [KO:K00025] [EC:1.1.1.37]
AT5G56720  c-NAD-MDH3; Lactate/malate dehydrogenase family protein [KO:K00025] [EC:1.1.1.37]
AT5G43330  c-NAD-MDH2; Lactate/malate dehydrogenase family protein [KO:K00025] [EC:1.1.1.37]
AT3G47520  MDH; malate dehydrogenase [KO:K00026] [EC:1.1.1.37]
AT1G53240  mMDH1; Lactate/malate dehydrogenase family protein [KO:K00026] [EC:1.1.1.37]
AT2G22780  PMDH1; peroxisomal NAD-malate dehydrogenase 1 [KO:K00026] [EC:1.1.1.37]
AT3G15020  mMDH2; Lactate/malate dehydrogenase family protein [KO:K00026] [EC:1.1.1.37]
AT5G09660  PMDH2; peroxisomal NAD-malate dehydrogenase 2 [KO:K00026] [EC:1.1.1.37]
AT2G42790  CSY3; citrate synthase 3 [KO:K01647] [EC:2.3.3.1]
AT3G58740  CSY1; citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
AT3G58750  CSY2; citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
AT3G60100  CSY5; citrate synthase 5 [KO:K01647] [EC:2.3.3.1]
AT2G44350  ATCS; Citrate synthase family protein [KO:K01647] [EC:2.3.3.1]
AT4G35830  ACO1; aconitase 1 [KO:K01681] [EC:4.2.1.3]
AT2G05710  ACO3; aconitase 3 [KO:K01681] [EC:4.2.1.3]
AT4G26970  ACO2; aconitase 2 [KO:K01681] [EC:4.2.1.3]
AT5G48230  ACAT2; acetoacetyl-CoA thiolase 2 [KO:K00626] [EC:2.3.1.9]
AT5G47720  AACT1; Thiolase family protein [KO:K00626] [EC:2.3.1.9]
AT3G14415  GOX2; Aldolase-type TIM barrel family protein [KO:K11517] [EC:1.1.3.15]
AT4G18360  GOX3; Aldolase-type TIM barrel family protein [KO:K11517] [EC:1.1.3.15]
AT3G14150  HAOX2; Aldolase-type TIM barrel family protein [KO:K11517] [EC:1.1.3.15]
AT3G14130  HAOX1; Aldolase-type TIM barrel family protein [KO:K11517] [EC:1.1.3.15]
AT3G14420  GOX1; Aldolase-type TIM barrel family protein [KO:K11517] [EC:1.1.3.15]
AT1G20630  CAT1; catalase 1 [KO:K03781] [EC:1.11.1.6]
AT4G35090  CAT2; catalase 2 [KO:K03781] [EC:1.11.1.6]
AT1G20620  CAT3; catalase 3 [KO:K03781] [EC:1.11.1.6]
AT1G79870  D-isomer specific 2-hydroxyacid dehydrogenase family protein [KO:K15919] [EC:1.1.1.79 1.1.1.81]
AT1G12550  HPR3; D-isomer specific 2-hydroxyacid dehydrogenase family protein [KO:K15919] [EC:1.1.1.79 1.1.1.81]
AT3G25530  GLYR1; glyoxylate reductase 1 [KO:K18121] [EC:1.1.1.79 1.1.1.-]
AT1G17650  GLYR2; glyoxylate reductase 2 [KO:K18121] [EC:1.1.1.79 1.1.1.-]
AT1G68010  HPR; hydroxypyruvate reductase [KO:K15893] [EC:1.1.1.29]
AT5G47760  PGLP2; 2-phosphoglycolate phosphatase 2 [KO:K19269] [EC:3.1.3.18 3.1.3.48]
AT5G36790  Haloacid dehalogenase-like hydrolase (HAD) superfamily protein [KO:K19269] [EC:3.1.3.18 3.1.3.48]
AT5G36700  PGLP1; 2-phosphoglycolate phosphatase 1 [KO:K19269] [EC:3.1.3.18 3.1.3.48]
ArthCp030  rbcL; ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit [KO:K01601] [EC:4.1.1.39]
AT1G67090  RBCS1A; ribulose bisphosphate carboxylase small chain 1A [KO:K01602] [EC:4.1.1.39]
AT5G38420  RBCS2B; Ribulose bisphosphate carboxylase (small chain) family protein [KO:K01602] [EC:4.1.1.39]
AT5G38410  RBCS3B; Ribulose bisphosphate carboxylase (small chain) family protein [KO:K01602] [EC:4.1.1.39]
AT5G38430  RBCS1B; Ribulose bisphosphate carboxylase (small chain) family protein [KO:K01602] [EC:4.1.1.39]
AT2G13360  AGT; alanine:glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
AT1G70580  AOAT2; alanine-2-oxoglutarate aminotransferase 2 [KO:K14272] [EC:2.6.1.4 2.6.1.2 2.6.1.44]
AT1G23310  GGT1; glutamate:glyoxylate aminotransferase [KO:K14272] [EC:2.6.1.4 2.6.1.2 2.6.1.44]
AT2G41220  GLU2; glutamate synthase 2 [KO:K00284] [EC:1.4.7.1]
AT5G04140  GLU1; glutamate synthase 1 [KO:K00284] [EC:1.4.7.1]
AT5G37600  GSR_1; uncharacterized protein [KO:K01915] [EC:6.3.1.2]
AT3G17820  GLN1.3; glutamine synthetase 1.3 [KO:K01915] [EC:6.3.1.2]
AT1G48470  GLN1;5; glutamine synthetase 1;5 [KO:K01915] [EC:6.3.1.2]
AT5G35630  GS2; glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
AT5G16570  GLN1;4; glutamine synthetase 1;4 [KO:K01915] [EC:6.3.1.2]
AT1G66200  GSR2; uncharacterized protein [KO:K01915] [EC:6.3.1.2]
AT4G13890  EDA36; Pyridoxal phosphate (PLP)-dependent transferases superfamily protein [KO:K00600] [EC:2.1.2.1]
AT4G13930  SHM4; serine hydroxymethyltransferase 4 [KO:K00600] [EC:2.1.2.1]
AT1G22020  SHM6; serine hydroxymethyltransferase 6 [KO:K00600] [EC:2.1.2.1]
AT4G32520  SHM3; serine hydroxymethyltransferase 3 [KO:K00600] [EC:2.1.2.1]
AT4G37930  SHM1; serine transhydroxymethyltransferase 1 [KO:K00600] [EC:2.1.2.1]
AT1G36370  SHM7; serine hydroxymethyltransferase 7 [KO:K00600] [EC:2.1.2.1]
AT5G26780  SHM2; serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
AT2G26080  GLDP2; glycine decarboxylase P-protein 2 [KO:K00281] [EC:1.4.4.2]
AT4G33010  GLDP1; glycine decarboxylase P-protein 1 [KO:K00281] [EC:1.4.4.2]
AT1G11860  Glycine cleavage T-protein family [KO:K00605] [EC:2.1.2.10]
AT3G17240  mtLPD2; lipoamide dehydrogenase 2 [KO:K00382] [EC:1.8.1.4]
AT3G16950  LPD1; lipoamide dehydrogenase 1 [KO:K00382] [EC:1.8.1.4]
AT1G48030  mtLPD1; mitochondrial lipoamide dehydrogenase 1 [KO:K00382] [EC:1.8.1.4]
AT4G16155  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
AT1G32470  Single hybrid motif superfamily protein [KO:K02437]
AT2G35120  Single hybrid motif superfamily protein [KO:K02437]
AT2G35370  GDCH; glycine decarboxylase complex H [KO:K02437]
AT1G80380  P-loop containing nucleoside triphosphate hydrolases superfamily protein [KO:K15918] [EC:2.7.1.31]
AT5G14780  FDH; formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
AT4G17360  Formyl transferase [KO:K01433] [EC:3.5.1.10]
AT5G47435  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
AT4G37550  Acetamidase/Formamidase family protein [KO:K01455] [EC:3.5.1.49]
AT4G37560  Acetamidase/Formamidase family protein [KO:K01455] [EC:3.5.1.49]
AT3G48990  AAE3; AMP-dependent synthetase and ligase family protein [KO:K22133] [EC:6.2.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
ath00010  Glycolysis / Gluconeogenesis
ath00020  Citrate cycle (TCA cycle)
ath00030  Pentose phosphate pathway
ath00053  Ascorbate and aldarate metabolism
ath00071  Fatty acid degradation
ath00230  Purine metabolism
ath00250  Alanine, aspartate and glutamate metabolism
ath00260  Glycine, serine and threonine metabolism
ath00620  Pyruvate metabolism
ath00710  Carbon fixation in photosynthetic organisms
ath00750  Vitamin B6 metabolism
ath00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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