KEGG   PATHWAY: bta00531
Entry
bta00531                    Pathway                                
Name
Glycosaminoglycan degradation - Bos taurus (cow)
Class
Metabolism; Glycan biosynthesis and metabolism
Pathway map
bta00531  Glycosaminoglycan degradation
bta00531

Module
bta_M00076  Dermatan sulfate degradation [PATH:bta00531]
bta_M00077  Chondroitin sulfate degradation [PATH:bta00531]
bta_M00078  Heparan sulfate degradation [PATH:bta00531]
bta_M00079  Keratan sulfate degradation [PATH:bta00531]
Other DBs
GO: 0006027
Organism
Bos taurus (cow) [GN:bta]
Gene
101904377  [KO:K01195] [EC:3.2.1.31]
281230  HPSE; heparanase precursor [KO:K07964] [EC:3.2.1.166]
281838  HYAL2; hyaluronidase-2 precursor [KO:K01197] [EC:3.2.1.35]
353352  SPAM1; sperm adhesion molecule 1 precursor [KO:K01197] [EC:3.2.1.35]
504468  HEXA; beta-hexosaminidase subunit alpha precursor [KO:K12373] [EC:3.2.1.52]
507188  GLB1; beta-galactosidase precursor [KO:K12309] [EC:3.2.1.23]
509761  [KO:K01197] [EC:3.2.1.35]
511050  IDUA; alpha-L-iduronidase isoform X1 [KO:K01217] [EC:3.2.1.76]
511607  HGSNAT; heparan-alpha-glucosaminide N-acetyltransferase isoform X1 [KO:K10532] [EC:2.3.1.78]
512444  GNS; N-acetylglucosamine-6-sulfatase precursor [KO:K01137] [EC:3.1.6.14]
515397  HYAL1; hyaluronidase-1 precursor [KO:K01197] [EC:3.2.1.35]
515687  GUSB; beta-glucuronidase precursor [KO:K01195] [EC:3.2.1.31]
515809  GALNS; N-acetylgalactosamine-6-sulfatase precursor [KO:K01132] [EC:3.1.6.4]
518161  HYAL4; hyaluronidase-4 [KO:K01197] [EC:3.2.1.35]
527125  [KO:K01197] [EC:3.2.1.35]
535442  SGSH; N-sulphoglucosamine sulphohydrolase precursor [KO:K01565] [EC:3.10.1.1]
537343  HPSE2; inactive heparanase-2 isoform X1 [KO:K07965] [EC:3.2.1.-]
538401  ARSB; arylsulfatase B precursor [KO:K01135] [EC:3.1.6.12]
541272  IDS; iduronate 2-sulfatase precursor [KO:K01136] [EC:3.1.6.13]
616562  HYAL3; hyaluronidase-3 precursor [KO:K01197] [EC:3.2.1.35]
618571  HEXB; beta-hexosaminidase subunit beta preproprotein [KO:K12373] [EC:3.2.1.52]
786974  [KO:K12373] [EC:3.2.1.52]
789125  NAGLU; alpha-N-acetylglucosaminidase precursor [KO:K01205] [EC:3.2.1.50]
Compound
C00426  Dermatan sulfate
C00573  Keratan sulfate
C00634  Chondroitin 4-sulfate
C00925  Heparan sulfate
G00526  
G00711  
G00872  DWA-2
G01391  
G01945  
G01977  
G02632  
G09660  
G10008  
G10505  Hyaluronic acid
G12336  
G13034  
G13035  
G13036  
G13037  
G13038  
G13039  
G13040  
G13041  
G13042  
G13043  
G13073  
G13074  
Reference
PMID:27570
  Authors
Greiling H, Stuhlsatz HW, Cantz M, Gehler J
  Title
Increased urinary excretion of keratan sulfate in fucosidosis.
  Journal
J Clin Chem Clin Biochem 16:329-34 (1978)
DOI:10.1515/cclm.1978.16.6.329
Reference
PMID:3161730
  Authors
Fuchs W, Beck M, Kresse H
  Title
Intralysosomal formation and metabolic fate of N-acetylglucosamine 6-sulfate from keratan sulfate.
  Journal
Eur J Biochem 151:551-6 (1985)
DOI:10.1111/j.1432-1033.1985.tb09138.x
Related
pathway
bta00532  Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
bta00533  Glycosaminoglycan biosynthesis - keratan sulfate
bta00534  Glycosaminoglycan biosynthesis - heparan sulfate / heparin
KO pathway
ko00531   

DBGET integrated database retrieval system