KEGG   PATHWAY: mmu00513
Entry
mmu00513                    Pathway                                
Name
Various types of N-glycan biosynthesis - Mus musculus (house mouse)
Class
Metabolism; Glycan biosynthesis and metabolism
Pathway map
mmu00513  Various types of N-glycan biosynthesis
mmu00513

Module
mmu_M00072  N-glycosylation by oligosaccharyltransferase [PATH:mmu00513]
Other DBs
GO: 0006487
Organism
Mus musculus (house mouse) [GN:mmu]
Gene
102580  Alg9; ALG9 alpha-1,2-mannosyltransferase [KO:K03846] [EC:2.4.1.259 2.4.1.261]
103534  Mgat4b; mannoside acetylglucosaminyltransferase 4, isoenzyme B [KO:K00738] [EC:2.4.1.145]
103963  Rpn1; ribophorin I [KO:K12666]
13135  Dad1; defender against cell death 1 [KO:K12668]
13200  Ddost; dolichyl-di-phosphooligosaccharide-protein glycotransferase [KO:K12670]
140481  Man2a2; mannosidase 2, alpha 2 [KO:K01231] [EC:3.2.1.114]
14595  B4galt1; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 [KO:K07966] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
15211  Hexa; hexosaminidase A [KO:K12373] [EC:3.2.1.52]
15212  Hexb; hexosaminidase B [KO:K12373] [EC:3.2.1.52]
16430  Stt3a; STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) [KO:K07151] [EC:2.4.99.18]
17155  Man1a; mannosidase 1, alpha [KO:K01230] [EC:3.2.1.113]
17156  Man1a2; mannosidase, alpha, class 1A, member 2 [KO:K01230] [EC:3.2.1.113]
17158  Man2a1; mannosidase 2, alpha 1 [KO:K01231] [EC:3.2.1.114]
17308  Mgat1; mannoside acetylglucosaminyltransferase 1 [KO:K00726] [EC:2.4.1.101]
20014  Rpn2; ribophorin II [KO:K12667]
20441  St3gal3; ST3 beta-galactoside alpha-2,3-sialyltransferase 3 [KO:K00781] [EC:2.4.3.6]
207958  Alg11; ALG11 alpha-1,2-mannosyltransferase [KO:K03844] [EC:2.4.1.131]
208211  Alg1; ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase [KO:K03842] [EC:2.4.1.142]
208624  Alg3; ALG3 alpha-1,3- mannosyltransferase [KO:K03845] [EC:2.4.1.258]
217664  Mgat2; mannoside acetylglucosaminyltransferase 2 [KO:K00736] [EC:2.4.1.143]
223774  Alg12; ALG12 alpha-1,6-mannosyltransferase [KO:K03847] [EC:2.4.1.260]
227619  Man1b1; mannosidase, alpha, class 1B, member 1 [KO:K23741]
230815  Man1c1; mannosidase, alpha, class 1C, member 1 [KO:K01230] [EC:3.2.1.113]
238023  Hexd; hexosaminidase D [KO:K14459] [EC:3.2.1.52]
269181  Mgat4a; mannoside acetylglucosaminyltransferase 4, isoenzyme A [KO:K00738] [EC:2.4.1.145]
320302  Glt28d2; glycosyltransferase 28 domain containing 2 [KO:K07432] [EC:2.4.1.141]
330406  B4galnt3; beta-1,4-N-acetyl-galactosaminyl transferase 3 [KO:K09656] [EC:2.4.1.244]
330671  B4galnt4; beta-1,4-N-acetyl-galactosaminyl transferase 4 [KO:K09657] [EC:2.4.1.244]
53418  B4galt2; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 [KO:K07967] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
53618  Fut8; fucosyltransferase 8 [KO:K00717] [EC:2.4.1.68]
56737  Alg2; ALG2 alpha-1,3/1,6-mannosyltransferase [KO:K03843] [EC:2.4.1.132 2.4.1.257]
57370  B4galt3; UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3 [KO:K07968] [EC:2.4.1.90 2.4.1.38 2.4.1.-]
66059  Krtcap2; keratinocyte associated protein 2 [KO:K28202]
66357  Ostc; oligosaccharyltransferase complex subunit (non-catalytic) [KO:K26501]
66789  Alg14; asparagine-linked glycosylation 14 [KO:K07441] [EC:2.4.1.141]
67075  Magt1; magnesium transporter 1 [KO:K19478]
67555  Mgat4d; MGAT4 family, member C [KO:K00738] [EC:2.4.1.145]
67569  Mgat4c; MGAT4 family, member C [KO:K13748] [EC:2.4.1.201 2.4.1.145]
67574  Alg13; asparagine-linked glycosylation 13 [KO:K07432] [EC:2.4.1.141]
68292  Stt3b; STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae) [KO:K07151] [EC:2.4.99.18]
68947  Chst8; carbohydrate sulfotransferase 8 [KO:K09672] [EC:2.8.2.-]
69038  Tmem258; transmembrane protein 258 [KO:K26502]
71367  Chst9; carbohydrate sulfotransferase 9 [KO:K09673] [EC:2.8.2.-]
80286  Tusc3; tumor suppressor candidate 3 [KO:K19478]
Compound
G00011  
G00012  
G00013  
G00014  
G00015  
G00016  Core fucose
G00017  
G00179  
G01813  
G05477  
G10665  
G10694  
G10716  
G10770  
G10841  
G10920  
G11000  
G11040  
G11933  
G12617  
G12625  
G12626  
G13047  
G13048  
G13049  
G13050  
G13055  
G13056  
G13057  
G13058  
G13059  
Reference
  Authors
Munro S.
  Title
What can yeast tell us about N-linked glycosylation in the Golgi apparatus?
  Journal
FEBS Lett 498:223-7 (2001)
DOI:10.1016/S0014-5793(01)02488-7
Reference
PMID:9878803
  Authors
Dean N.
  Title
Asparagine-linked glycosylation in the yeast Golgi.
  Journal
Biochim Biophys Acta 1426:309-22 (1999)
DOI:10.1016/S0304-4165(98)00132-9
Reference
PMID:9878780
  Authors
Herscovics A.
  Title
Processing glycosidases of Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1426:275-85 (1999)
DOI:10.1016/S0304-4165(98)00129-9
Reference
PMID:9218445
  Authors
Wang XH, Nakayama K, Shimma Y, Tanaka A, Jigami Y.
  Title
MNN6, a member of the KRE2/MNT1 family, is the gene for mannosylphosphate transfer in Saccharomyces cerevisiae.
  Journal
J Biol Chem 272:18117-24 (1997)
DOI:10.1074/jbc.272.29.18117
Reference
PMID:9756928
  Authors
Rayner JC, Munro S.
  Title
Identification of the MNN2 and MNN5 mannosyltransferases required for forming and extending the mannose branches of the outer chain mannans of Saccharomyces cerevisiae.
  Journal
J Biol Chem 273:26836-43 (1998)
DOI:10.1074/jbc.273.41.26836
Reference
  Authors
Jungmann J, Rayner JC, Munro S.
  Title
The Saccharomyces cerevisiae protein Mnn10p/Bed1p is a subunit of a Golgi mannosyltransferase complex.
  Journal
J Biol Chem 274:6579-85 (1999)
DOI:10.1074/jbc.274.10.6579
Reference
PMID:8253757
  Authors
Nakanishi-Shindo Y, Nakayama K, Tanaka A, Toda Y, Jigami Y.
  Title
Structure of the N-linked oligosaccharides that show the complete loss of alpha-1,6-polymannose outer chain from och1, och1 mnn1, and och1 mnn1 alg3 mutants of Saccharomyces cerevisiae.
  Journal
J Biol Chem 268:26338-45 (1993)
Reference
  Authors
Gomord V, Fitchette AC, Menu-Bouaouiche L, Saint-Jore-Dupas C, Plasson C, Michaud D, Faye L
  Title
Plant-specific glycosylation patterns in the context of therapeutic protein production.
  Journal
Plant Biotechnol J 8:564-87 (2010)
DOI:10.1111/j.1467-7652.2009.00497.x
Related
pathway
mmu00510  N-Glycan biosynthesis
KO pathway
ko00513   

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