KEGG   PATHWAY: mmu04144
Entry
mmu04144                    Pathway                                
Name
Endocytosis - Mus musculus (house mouse)
Description
Endocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins entering through clathrin-dependent endocytosis (CDE) have sequences in their cytoplasmic domains that bind to the APs (adaptor-related protein complexes) and enable their rapid removal from the PM. In addition to APs and clathrin, there are numerous accessory proteins including dynamin. Depending on the various proteins that enter the endosome membrane, these cargoes are sorted to distinct destinations. Some cargoes, such as nutrient receptors, are recycled back to the PM. Ubiquitylated membrane proteins, such as activated growth-factor receptors, are sorted into intraluminal vesicles and eventually end up in the lysosome lumen via multivesicular endosomes (MVEs). There are distinct mechanisms of clathrin-independent endocytosis (CIE) depending upon the cargo and the cell type.
Class
Cellular Processes; Transport and catabolism
Pathway map
mmu04144  Endocytosis
mmu04144

Other DBs
GO: 0006897
Organism
Mus musculus (house mouse) [GN:mmu]
Gene
100017  Ldlrap1; low density lipoprotein receptor adaptor protein 1 [KO:K12474]
100529082  H2-T27; histocompatibility 2, T region locus 27 [KO:K06751]
103967  Dnm3; dynamin 3 [KO:K01528] [EC:3.6.5.5]
105513  Chmp7; charged multivesicular body protein 7 [KO:K15053]
106572  Rab31; RAB31, member RAS oncogene family [KO:K07891]
106952  Arap3; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [KO:K12490]
107305  Vps37c; vacuolar protein sorting 37C [KO:K12185]
107338  Gbf1; golgi-specific brefeldin A-resistance factor 1 [KO:K18443]
107568  Wwp1; WW domain containing E3 ubiquitin protein ligase 1 [KO:K05633] [EC:2.3.2.26]
109689  Arrb1; arrestin, beta 1 [KO:K04439]
110355  Grk2; G protein-coupled receptor kinase 2 [KO:K00910] [EC:2.7.11.15]
110557  H2-Q6; histocompatibility 2, Q region locus 6 [KO:K06751]
110558  H2-Q9; histocompatibility 2, Q region locus 9 [KO:K06751]
110696  H2-M10.3; histocompatibility 2, M region locus 10.3 [KO:K06751]
116733  Vps4a; vacuolar protein sorting 4A [KO:K12196]
11771  Ap2a1; adaptor-related protein complex 2, alpha 1 subunit [KO:K11824]
11772  Ap2a2; adaptor-related protein complex 2, alpha 2 subunit [KO:K11824]
11773  Ap2m1; adaptor-related protein complex 2, mu 1 subunit [KO:K11826]
11840  Arf1; ADP-ribosylation factor 1 [KO:K07937]
11841  Arf2; ADP-ribosylation factor 2 [KO:K07937]
11842  Arf3; ADP-ribosylation factor 3 [KO:K07938]
11843  Arf4; ADP-ribosylation factor 4 [KO:K07939]
11844  Arf5; ADP-ribosylation factor 5 [KO:K07940]
11845  Arf6; ADP-ribosylation factor 6 [KO:K07941]
11848  Rhoa; ras homolog family member A [KO:K04513]
11867  Arpc1b; actin related protein 2/3 complex, subunit 1B [KO:K05757]
12340  Capza1; capping actin protein of muscle Z-line subunit alpha 1 [KO:K10364]
12343  Capza2; capping actin protein of muscle Z-line subunit alpha 2 [KO:K10364]
12344  Capza3; capping actin protein of muscle Z-line subunit alpha 3 [KO:K10364]
12345  Capzb; capping actin protein of muscle Z-line subunit beta [KO:K10365]
12389  Cav1; caveolin 1, caveolae protein [KO:K06278]
12390  Cav2; caveolin 2 [KO:K12958]
12391  Cav3; caveolin 3 [KO:K12959]
12402  Cbl; Casitas B-lineage lymphoma [KO:K04707] [EC:2.3.2.27]
125179616  Gm57851; predicted gene, 57851 [KO:K12199]
12540  Cdc42; cell division cycle 42 [KO:K04393]
12757  Clta; clathrin light chain A [KO:K04644]
12765  Cxcr2; C-X-C motif chemokine receptor 2 [KO:K05050]
12767  Cxcr4; C-X-C motif chemokine receptor 4 [KO:K04189]
12774  Ccr5; C-C motif chemokine receptor 5 [KO:K04180]
13132  Dab2; disabled 2, mitogen-responsive phosphoprotein [KO:K12475]
13196  Asap1; ArfGAP with SH3 domain, ankyrin repeat and PH domain1 [KO:K12488]
13429  Dnm1; dynamin 1 [KO:K01528] [EC:3.6.5.5]
13430  Dnm2; dynamin 2 [KO:K23484]
13649  Egfr; epidermal growth factor receptor [KO:K04361] [EC:2.7.10.1]
13660  Ehd1; EH-domain containing 1 [KO:K12483]
13854  Epn1; epsin 1 [KO:K12471]
13855  Epn2; epsin 2 [KO:K12471]
13858  Eps15; epidermal growth factor receptor pathway substrate 15 [KO:K12472]
13859  Eps15l1; epidermal growth factor receptor pathway substrate 15-like 1 [KO:K12472]
140500  Acap3; ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 [KO:K12489]
14183  Fgfr2; fibroblast growth factor receptor 2 [KO:K05093] [EC:2.7.10.1]
14184  Fgfr3; fibroblast growth factor receptor 3 [KO:K05094] [EC:2.7.10.1]
14186  Fgfr4; fibroblast growth factor receptor 4 [KO:K05095] [EC:2.7.10.1]
14275  Folr1; folate receptor alpha [KO:K13649]
14276  Folr2; folate receptor beta [KO:K13649]
14772  Grk4; G protein-coupled receptor kinase 4 [KO:K08291] [EC:2.7.11.16]
14773  Grk5; G protein-coupled receptor kinase 5 [KO:K08291] [EC:2.7.11.16]
14963  H2-Bl; histocompatibility 2, blastocyst [KO:K06751]
14964  H2-D1; histocompatibility 2, D region locus 1 [KO:K06751]
14972  H2-K1; histocompatibility 2, K1, K region [KO:K06751]
14980  H2-L; histocompatibility 2, D region locus L [KO:K06751]
14985  H2-M10.1; histocompatibility 2, M region locus 10.1 [KO:K06751]
14990  H2-M2; histocompatibility 2, M region locus 2 [KO:K06751]
14991  H2-M3; histocompatibility 2, M region locus 3 [KO:K06751]
14997  H2-M9; histocompatibility 2, M region locus 9 [KO:K06751]
15006  H2-Q1; histocompatibility 2, Q region locus 1 [KO:K06751]
15007  H2-Q10; histocompatibility 2, Q region locus 10 [KO:K06751]
15013  H2-Q2; histocompatibility 2, Q region locus 2 [KO:K06751]
15015  H2-Q4; histocompatibility 2, Q region locus 4 [KO:K06751]
15018  H2-Q7; histocompatibility 2, Q region locus 7 [KO:K06751]
15024  H2-T10; histocompatibility 2, T region locus 10 [KO:K06751]
15039  H2-T22; histocompatibility 2, T region locus 22 [KO:K06751]
15040  H2-T23; histocompatibility 2, T region locus 23 [KO:K06751]
15042  H2-T24; histocompatibility 2, T region locus 24 [KO:K06751]
15043  H2-T3; histocompatibility 2, T region locus 3 [KO:K06751]
15239  Hgs; HGF-regulated tyrosine kinase substrate [KO:K12182]
15461  Hras; Harvey rat sarcoma virus oncogene [KO:K02833]
15481  Hspa8; heat shock protein 8 [KO:K03283]
15482  Hspa1l; heat shock protein 1-like [KO:K03283]
15511  Hspa1b; heat shock protein 1B [KO:K03283]
16001  Igf1r; insulin-like growth factor I receptor [KO:K05087] [EC:2.7.10.1]
16004  Igf2r; insulin-like growth factor 2 receptor [KO:K06564]
16184  Il2ra; interleukin 2 receptor, alpha chain [KO:K05068]
16185  Il2rb; interleukin 2 receptor, beta chain [KO:K05069]
16186  Il2rg; interleukin 2 receptor, gamma chain [KO:K05070]
16396  Itch; itchy, E3 ubiquitin protein ligase [KO:K05632] [EC:2.3.2.26]
16572  Kif5a; kinesin family member 5A [KO:K10396] [EC:5.6.1.3]
16573  Kif5b; kinesin family member 5B [KO:K10396] [EC:5.6.1.3]
16574  Kif5c; kinesin family member 5C [KO:K10396] [EC:5.6.1.3]
16835  Ldlr; low density lipoprotein receptor [KO:K12473]
17126  Smad2; SMAD family member 2 [KO:K04500]
17127  Smad3; SMAD family member 3 [KO:K23605]
17246  Mdm2; transformed mouse 3T3 cell double minute 2 [KO:K06643] [EC:2.3.2.27]
17274  Rab8a; RAB8A, member RAS oncogene family [KO:K07901]
17999  Nedd4; neural precursor cell expressed, developmentally down-regulated 4 [KO:K10591] [EC:2.3.2.26]
18571  Pdcd6ip; programmed cell death 6 interacting protein [KO:K12200]
18595  Pdgfra; platelet derived growth factor receptor, alpha polypeptide [KO:K04363] [EC:2.7.10.1]
18717  Pip5k1c; phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma [KO:K00889] [EC:2.7.1.68]
18719  Pip5k1b; phosphatidylinositol-4-phosphate 5-kinase, type 1 beta [KO:K00889] [EC:2.7.1.68]
18720  Pip5k1a; phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha [KO:K00889] [EC:2.7.1.68]
18759  Prkci; protein kinase C, iota [KO:K06069] [EC:2.7.11.13]
18762  Prkcz; protein kinase C, zeta [KO:K18952] [EC:2.7.11.13]
18805  Pld1; phospholipase D1 [KO:K01115] [EC:3.1.4.4]
18806  Pld2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
18854  Pml; promyelocytic leukemia [KO:K10054] [EC:2.3.2.-]
19157  Cyth1; cytohesin 1 [KO:K18441]
19158  Cyth2; cytohesin 2 [KO:K18441]
19159  Cyth3; cytohesin 3 [KO:K18441]
19325  Rab10; RAB10, member RAS oncogene family [KO:K07903]
19326  Rab11b; RAB11B, member RAS oncogene family [KO:K07905]
19334  Rab22a; RAB22A, member RAS oncogene family [KO:K07891]
19341  Rab4a; RAB4A, member RAS oncogene family [KO:K07879]
19344  Rab5b; RAB5B, member RAS oncogene family [KO:K07888]
19345  Rab5c; RAB5C, member RAS oncogene family [KO:K07889]
19349  Rab7; RAB7, member RAS oncogene family [KO:K07897]
193740  Hspa1a; heat shock protein 1A [KO:K03283]
194309  Vps37d; vacuolar protein sorting 37D [KO:K12185]
20404  Sh3gl2; SH3-domain GRB2-like 2 [KO:K11247]
20405  Sh3gl1; SH3-domain GRB2-like 1 [KO:K11247]
20408  Sh3gl3; SH3-domain GRB2-like 3 [KO:K11247]
20479  Vps4b; vacuolar protein sorting 4B [KO:K12196]
20779  Src; Rous sarcoma oncogene [KO:K05704] [EC:2.7.10.2]
208092  Chmp6; charged multivesicular body protein 6 [KO:K12195]
20844  Stam; signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 [KO:K04705]
208650  Cblb; Casitas B-lineage lymphoma b [KO:K22517] [EC:2.3.2.27]
211673  Arfgef1; ADP ribosylation factor guanine nucleotide exchange factor 1 [KO:K18442]
211914  Asap2; ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 [KO:K12488]
212285  Arap2; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 [KO:K18440]
213990  Agap3; ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 [KO:K12491]
215280  Wipf1; WAS/WASL interacting protein family, member 1 [KO:K19475]
215445  Rab11fip3; RAB11 family interacting protein 3 (class II) [KO:K12485]
215632  Psd4; pleckstrin and Sec7 domain containing 4 [KO:K12494]
216238  Eea1; early endosome antigen 1 [KO:K12478]
216439  Agap2; ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 [KO:K17848]
216724  Rufy1; RUN and FYVE domain containing 1 [KO:K12482]
216859  Acap1; ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 [KO:K12489]
216869  Arrb2; arrestin, beta 2 [KO:K04439]
216963  Git1; GIT ArfGAP 1 [KO:K05737]
218038  Amph; amphiphysin [KO:K12562]
21812  Tgfbr1; transforming growth factor, beta receptor I [KO:K04674] [EC:2.7.11.30]
21813  Tgfbr2; transforming growth factor, beta receptor II [KO:K04388] [EC:2.7.11.30]
218441  Zfyve16; zinc finger, FYVE domain containing 16 [KO:K04679]
22034  Traf6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
22042  Tfrc; transferrin receptor [KO:K06503]
22088  Tsg101; tumor susceptibility gene 101 [KO:K12183]
223593  Washc5; WASH complex subunit 5 [KO:K18464]
22365  Vps45; vacuolar protein sorting 45 [KO:K12479]
224753  H2-M10.4; histocompatibility 2, M region locus 10.4 [KO:K06751]
224754  H2-M11; histocompatibility 2, M region locus 11 [KO:K06751]
224756  H2-M1; histocompatibility 2, M region locus 1 [KO:K06751]
224761  H2-M10.5; histocompatibility 2, M region locus 10.5 [KO:K06751]
225861  Snx32; sorting nexin 32 [KO:K17920]
227288  Cxcr1; C-X-C motif chemokine receptor 1 [KO:K04175]
227700  Sh3glb2; SH3-domain GRB2-like endophilin B2 [KO:K21269]
227733  Pip5kl1; phosphatidylinositol-4-phosphate 5-kinase-like 1 [KO:K13712] [EC:2.7.1.68]
228998  Arfgap1; ADP-ribosylation factor GTPase activating protein 1 [KO:K12492]
229285  Spart; spartin [KO:K19366]
230597  Zfyve9; zinc finger, FYVE domain containing 9 [KO:K04679]
230837  Asap3; ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 [KO:K12488]
232227  Iqsec1; IQ motif and Sec7 domain 1 [KO:K12495]
232910  Ap2s1; adaptor-related protein complex 2, sigma 1 subunit [KO:K11827]
234353  Psd3; pleckstrin and Sec7 domain containing 3 [KO:K12494]
234852  Chmp1a; charged multivesicular body protein 1A [KO:K12197]
240095  H2-M5; histocompatibility 2, M region locus 5 [KO:K06751]
24013  Grk1; G protein-coupled receptor kinase 1 [KO:K00909] [EC:2.7.11.14]
242894  Actr3b; ARP3 actin-related protein 3B [KO:K18584]
243621  Iqsec3; IQ motif and Sec7 domain 3 [KO:K12495]
245666  Iqsec2; IQ motif and Sec7 domain 2 [KO:K12495]
259300  Ehd2; EH-domain containing 2 [KO:K12469]
26385  Grk6; G protein-coupled receptor kinase 6 [KO:K08291] [EC:2.7.11.16]
26431  Git2; GIT ArfGAP 2 [KO:K12487]
268451  Rab11fip4; RAB11 family interacting protein 4 (class II) [KO:K12485]
271457  Rab5a; RAB5A, member RAS oncogene family [KO:K07887]
27681  Snf8; SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) [KO:K12188]
27965  Spg21; SPG21, maspardin [KO:K19367]
28006  Washc2; WASH complex subunit 2 [KO:K18462]
28084  Vps25; vacuolar protein sorting 25 [KO:K12189]
30930  Vps26a; VPS26 retromer complex component A [KO:K18466]
30948  Bin1; bridging integrator 1 [KO:K12562]
319277  Washc4; WASH complex subunit 4 [KO:K18465]
319740  Zfyve27; zinc finger, FYVE domain containing 27 [KO:K19368]
320129  Grk3; G protein-coupled receptor kinase 3 [KO:K00910] [EC:2.7.11.15]
330192  Vps37b; vacuolar protein sorting 37B [KO:K12185]
330319  Wipf3; WAS/WASL interacting protein family, member 3 [KO:K19475]
333715  H2-M10.2; histocompatibility 2, M region locus 10.2 [KO:K06751]
347722  Agap1; ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 [KO:K12491]
399549  H2-M10.6; histocompatibility 2, M region locus 10.6 [KO:K06751]
434782  Gm5637; predicted pseudogene 5637 [KO:K05757]
52055  Rab11fip5; RAB11 family interacting protein 5 (class I) [KO:K12484]
52348  Vps37a; vacuolar protein sorting 37A [KO:K12185]
53869  Rab11a; RAB11A, member RAS oncogene family [KO:K07904]
54189  Rabep1; rabaptin, RAB GTPase binding effector protein 1 [KO:K12480]
54198  Snx3; sorting nexin 3 [KO:K17918]
54673  Sh3glb1; SH3-domain GRB2-like B1 (endophilin) [KO:K11248]
547349  H2-K1; MHC class I family member [KO:K06751]
55988  Snx12; sorting nexin 12 [KO:K17918]
56324  Stam2; signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 [KO:K04705]
56378  Arpc3; actin related protein 2/3 complex, subunit 3 [KO:K05756]
56433  Vps29; VPS29 retromer complex component [KO:K18467]
56440  Snx1; sorting nexin 1 [KO:K17917]
56443  Arpc1a; actin related protein 2/3 complex, subunit 1A [KO:K05757]
56513  Pard6a; par-6 family cell polarity regulator alpha [KO:K06093]
57440  Ehd3; EH-domain containing 3 [KO:K12476]
58194  Sh3kbp1; SH3-domain kinase binding protein 1 [KO:K12470]
58220  Pard6b; par-6 family cell polarity regulator beta [KO:K06093]
630294  H2-T25; histocompatibility-2, T region locus 25 [KO:K06751]
65114  Vps35; VPS35 retromer complex component [KO:K18468]
66201  Vta1; vesicle (multivesicular body) trafficking 1 [KO:K12199]
66251  Arfgap3; ADP-ribosylation factor GTPase activating protein 3 [KO:K12493]
66313  Smurf2; SMAD specific E3 ubiquitin protein ligase 2 [KO:K04678] [EC:2.3.2.26]
66371  Chmp4c; charged multivesicular body protein 4C [KO:K24782]
66700  Chmp3; charged multivesicular body protein 3 [KO:K12193]
66713  Actr2; actin related protein 2 [KO:K17260]
667977  H2-T26; histocompatibility 2, T region locus 26 [KO:K06751]
66914  Vps28; vacuolar protein sorting 28 [KO:K12184]
67028  Chmp1b2; charged multivesicular body protein 1B2 [KO:K12197]
67064  Chmp1b; charged multivesicular body protein 1B [KO:K12197]
67282  Washc3; WASH complex subunit 3 [KO:K18463]
67300  Cltc; clathrin heavy chain [KO:K04646]
67588  Rnf41; ring finger protein 41 [KO:K11981] [EC:2.3.2.27]
67653  4930544G11Rik; RIKEN cDNA 4930544G11 gene [KO:K04513]
67771  Arpc5; actin related protein 2/3 complex, subunit 5 [KO:K05754]
67804  Snx2; sorting nexin 2 [KO:K17917]
68089  Arpc4; actin related protein 2/3 complex, subunit 4 [KO:K05755]
68524  Wipf2; WAS/WASL interacting protein family, member 2 [KO:K19475]
68767  Washc1; WASH complex subunit 1 [KO:K18461]
68942  Chmp2b; charged multivesicular body protein 2B [KO:K12192]
68953  Chmp2a; charged multivesicular body protein 2A [KO:K12191]
69091  Vps26b; VPS26 retromer complex component B [KO:K18466]
69150  Snx4; sorting nexin 4 [KO:K17919]
69178  Snx5; sorting nexin 5 [KO:K17920]
69710  Arap1; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [KO:K18439]
69717  Gm10499; predicted gene 10499 [KO:K06751]
69780  Smap2; small ArfGAP 2 [KO:K12486]
70160  Vps36; vacuolar protein sorting 36 [KO:K12190]
70432  Rufy2; RUN and FYVE domain-containing 2 [KO:K12482]
70527  Stambp; STAM binding protein [KO:K11866] [EC:3.4.19.12]
71770  Ap2b1; adaptor-related protein complex 2, beta 1 subunit [KO:K11825]
71889  Epn3; epsin 3 [KO:K12471]
71955  Ist1; increased sodium tolerance 1 homolog (yeast) [KO:K19476]
72183  Snx6; sorting nexin 6 [KO:K17920]
72318  Cyth4; cytohesin 4 [KO:K18441]
72543  Mvb12b; multivesicular body subunit 12B [KO:K12186]
72685  Dnajc6; DnaJ heat shock protein family (Hsp40) member C6 [KO:K09526]
73178  Wasl; WASP like actin nucleation promoting factor [KO:K23612]
73711  Mvb12a; multivesicular body subunit 12A [KO:K12186]
73728  Psd; pleckstrin and Sec7 domain containing [KO:K12494]
74002  Psd2; pleckstrin and Sec7 domain containing 2 [KO:K12494]
74117  Actr3; ARP3 actin-related protein 3 [KO:K18584]
74192  Arpc5l; actin related protein 2/3 complex, subunit 5-like [KO:K05754]
74325  Cltb; clathrin light chain B [KO:K04645]
74998  Rab11fip2; RAB11 family interacting protein 2 (class I) [KO:K12484]
75608  Chmp4b; charged multivesicular body protein 4B [KO:K12194]
75767  Rab11fip1; RAB11 family interacting protein 1 (class I) [KO:K12484]
75788  Smurf1; SMAD specific E3 ubiquitin protein ligase 1 [KO:K04678] [EC:2.3.2.26]
76709  Arpc2; actin related protein 2/3 complex, subunit 2 [KO:K05758]
76959  Chmp5; charged multivesicular body protein 5 [KO:K12198]
77038  Arfgap2; ADP-ribosylation factor GTPase activating protein 2 [KO:K12493]
77407  Rab35; RAB35, member RAS oncogene family [KO:K07876]
78287  Rbsn; rabenosyn, RAB effector [KO:K12481]
78618  Acap2; ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 [KO:K12489]
80794  Cblc; Casitas B-lineage lymphoma c [KO:K22518] [EC:2.3.2.27]
83814  Nedd4l; neural precursor cell expressed, developmentally down-regulated gene 4-like [KO:K13305] [EC:2.3.2.26]
84092  Usp8; ubiquitin specific peptidase 8 [KO:K11839] [EC:3.4.19.12]
93737  Pard6g; par-6 family cell polarity regulator gamma [KO:K06093]
93742  Pard3; par-3 family cell polarity regulator [KO:K04237]
98366  Smap1; small ArfGAP 1 [KO:K12486]
98878  Ehd4; EH-domain containing 4 [KO:K12477]
99371  Arfgef2; ADP ribosylation factor guanine nucleotide exchange factor 2 [KO:K18442]
Compound
C00035  GDP
C00044  GTP
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
Reference
PMID:19007773
  Authors
Acconcia F, Sigismund S, Polo S
  Title
Ubiquitin in trafficking: the network at work.
  Journal
Exp Cell Res 315:1610-8 (2009)
DOI:10.1016/j.yexcr.2008.10.014
Reference
PMID:18647649
  Authors
Donaldson JG, Porat-Shliom N, Cohen LA
  Title
Clathrin-independent endocytosis: a unique platform for cell signaling and PM remodeling.
  Journal
Cell Signal 21:1-6 (2009)
DOI:10.1016/j.cellsig.2008.06.020
Reference
PMID:15261671
  Authors
Sorkin A
  Title
Cargo recognition during clathrin-mediated endocytosis: a team effort.
  Journal
Curr Opin Cell Biol 16:392-9 (2004)
DOI:10.1016/j.ceb.2004.06.001
Reference
PMID:19325624
  Authors
Raiborg C, Stenmark H
  Title
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins.
  Journal
Nature 458:445-52 (2009)
DOI:10.1038/nature07961
Reference
PMID:20110990
  Authors
Scita G, Di Fiore PP
  Title
The endocytic matrix.
  Journal
Nature 463:464-73 (2010)
DOI:10.1038/nature08910
Reference
PMID:15687999
  Authors
Le Roy C, Wrana JL
  Title
Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling.
  Journal
Nat Rev Mol Cell Biol 6:112-26 (2005)
DOI:10.1038/nrm1571
Reference
PMID:19924646
  Authors
Jovic M, Sharma M, Rahajeng J, Caplan S
  Title
The early endosome: a busy sorting station for proteins at the crossroads.
  Journal
Histol Histopathol 25:99-112 (2010)
DOI:10.14670/HH-25.99
Reference
PMID:16203612
  Authors
Pietiainen VM, Marjomaki V, Heino J, Hyypia T
  Title
Viral entry, lipid rafts and caveosomes.
  Journal
Ann Med 37:394-403 (2005)
DOI:10.1080/07853890510011976
Reference
PMID:19696797
  Authors
Grant BD, Donaldson JG
  Title
Pathways and mechanisms of endocytic recycling.
  Journal
Nat Rev Mol Cell Biol 10:597-608 (2009)
DOI:10.1038/nrm2755
Reference
PMID:22193161
  Authors
Cullen PJ, Korswagen HC
  Title
Sorting nexins provide diversity for retromer-dependent trafficking events.
  Journal
Nat Cell Biol 14:29-37 (2012)
DOI:10.1038/ncb2374
Related
pathway
mmu04060  Cytokine-cytokine receptor interaction
mmu04070  Phosphatidylinositol signaling system
mmu04130  SNARE interactions in vesicular transport
mmu04142  Lysosome
mmu04350  TGF-beta signaling pathway
KO pathway
ko04144   

DBGET integrated database retrieval system