KEGG   PATHWAY: xla04810
Entry
xla04810                    Pathway                                
Name
Regulation of actin cytoskeleton - Xenopus laevis (African clawed frog)
Class
Cellular Processes; Cell motility
Pathway map
xla04810  Regulation of actin cytoskeleton
xla04810

Other DBs
GO: 0030036
Organism
Xenopus laevis (African clawed frog) [GN:xla]
Gene
100036831  arpc3-a; actin-related protein 2/3 complex subunit 3-A [KO:K05756]
100036841  pip4k2b.S; phosphatidylinositol-5-phosphate 4-kinase, type II, beta S homeolog [KO:K00920] [EC:2.7.1.149]
100037105  brk1.S; probable protein BRICK1-B [KO:K05752]
100101279  fgf2; fibroblast growth factor 2 [KO:K18497]
100191022  itga2b.1.S; integrin subunit alpha 2b S homeolog precursor [KO:K06476]
100192360  cxcr4.L; C-X-C chemokine receptor type 4-A [KO:K04189]
100216329  myh11.S; myosin-11 isoform X2 [KO:K10352]
100301953  rock2.S; uncharacterized protein LOC100301953 [KO:K17388] [EC:2.7.11.39]
100337595  actg1.S; actin, cytoplasmic type 5 [KO:K05692]
100505423  [KO:K07827]
100653493  pip5k1a.S; uncharacterized protein LOC100653493 [KO:K00889] [EC:2.7.1.68]
101027274  fgf19.L; fibroblast growth factor 19 [KO:K22603]
101027307  fgf5.S; fibroblast growth factor 5 [KO:K04358]
108695261  rock1.S; rho-associated protein kinase 1 [KO:K04514] [EC:2.7.11.39]
108695446  cyrib.S; CYFIP-related Rac1 interactor B isoform X1 [KO:K27976]
108695600  myl12b.S; myosin regulatory light chain 2, smooth muscle minor isoform [KO:K12757]
108696063  lpar5.L; lysophosphatidic acid receptor 5 [KO:K08390]
108696117  dock1.L; dedicator of cytokinesis protein 1 isoform X2 [KO:K13708]
108696425  arhgef12.L; rho guanine nucleotide exchange factor 12 isoform X1 [KO:K07532]
108696665  [KO:K10352]
108696670  [KO:K17457]
108696695  arhgef1.L; rho guanine nucleotide exchange factor 1 isoform X1 [KO:K12330]
108696729  [KO:K07830]
108696734  XB5961731.L; insulin [KO:K04526]
108696768  [KO:K22429]
108696771  [KO:K05627]
108697104  myl2.L; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
108697350  lpar5.S; lysophosphatidic acid receptor 5 isoform X1 [KO:K08390]
108697372  fgfr2.S; fibroblast growth factor receptor 2-like isoform X1 [KO:K05093] [EC:2.7.10.1]
108697392  dock1.S; dedicator of cytokinesis protein 1 isoform X3 [KO:K13708]
108697431  fgf8.S; fibroblast growth factor 8 isoform X1 [KO:K04358]
108697525  cxcl12.S; stromal cell-derived factor 1 isoform X1 [KO:K10031]
108697660  cdc42.S; cell division control protein 42 homolog isoform X1 [KO:K04393]
108697741  [KO:K17457]
108697757  arhgef1.S; rho guanine nucleotide exchange factor 1 isoform X1 [KO:K12330]
108697778  [KO:K07830]
108697792  kras.S; GTPase HRas [KO:K07827]
108697814  [KO:K05627]
108698197  vav2.L; guanine nucleotide exchange factor VAV2 isoform X1 [KO:K05730]
108698207  gsn.L; gelsolin-like isoform X2 [KO:K05768]
108698265  [KO:K26108]
108698341  [KO:K04358]
108698412  diaph2.L; protein diaphanous homolog 2 isoform X1 [KO:K05741]
108698497  arhgef6.L; rho guanine nucleotide exchange factor 6 isoform X1 [KO:K05729]
108698737  bdkrb2.L; B2 bradykinin receptor [KO:K03916]
108698752  sos2.L; son of sevenless homolog 2 isoform X2 [KO:K03099]
108698803  [KO:K04456] [EC:2.7.11.1]
108698858  c5.2.L; complement C5-like isoform X1 [KO:K03994]
108698859  c5.L; complement C5 isoform X1 [KO:K03994]
108699222  chrm5.L; muscarinic acetylcholine receptor M5 [KO:K04133]
108699243  pdgfc.L; platelet-derived growth factor C [KO:K05450]
108699252  pak6.L; serine/threonine-protein kinase PAK 6 [KO:K05735] [EC:2.7.11.1]
108699395  iqgap3.L; ras GTPase-activating-like protein IQGAP3 [KO:K05767]
108699471  [KO:K00889] [EC:2.7.1.68]
108699602  itga10.L; integrin alpha-10 [KO:K06586]
108699716  chrm5.S; muscarinic acetylcholine receptor M5 [KO:K04133]
108699719  cfl2.S; cofilin-2-like isoform X1 [KO:K05765]
108699793  sos2.S; son of sevenless homolog 2 [KO:K03099]
108699809  bdkrb2.S; B2 bradykinin receptor [KO:K03916]
108699874  c8g.S; complement component C8 gamma chain [KO:K03999]
108699987  fgd1.S; FYVE, RhoGEF and PH domain-containing protein 1 isoform X1 [KO:K05720]
108700051  msn.S; moesin isoform X1 [KO:K05763]
108700069  fgf16.S; fibroblast growth factor 16 [KO:K04358]
108700104  pak3.S; serine/threonine-protein kinase PAK 3-like isoform X2 [KO:K05733] [EC:2.7.11.1]
108700165  lpar4.S; lysophosphatidic acid receptor 4 [KO:K04275]
108700183  arhgef6.S; rho guanine nucleotide exchange factor 6 isoform X2 [KO:K05729]
108700189  arhgap35.S; rho GTPase-activating protein 35-like isoform X1 [KO:K05732]
108700290  pak4.S; serine/threonine-protein kinase PAK 4 [KO:K05734] [EC:2.7.11.1]
108700316  pak6.S; serine/threonine-protein kinase PAK 6 [KO:K05735] [EC:2.7.11.1]
108700357  insrr.S; insulin receptor-related protein [KO:K05086] [EC:2.7.10.1]
108700969  [KO:K00907] [EC:2.7.11.18]
108700975  [KO:K07861]
108700988  baiap2.L; brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X7 [KO:K05627]
108701118  itgb4.L; integrin beta-4 isoform X1 [KO:K06525]
108701185  [KO:K10352]
108701201  [KO:K05757]
108701204  gna13.L; guanine nucleotide-binding protein subunit alpha-13 [KO:K04639]
108701232  actr3.L; actin-related protein 3-B [KO:K18584]
108701256  mylk.L; myosin light chain kinase, smooth muscle isoform X1 [KO:K00907] [EC:2.7.11.18]
108701397  itga4.L; integrin alpha-4-like [KO:K06483]
108701434  abi2.L; abl interactor 2 isoform X1 [KO:K05751]
108701477  [KO:K00921] [EC:2.7.1.150]
108701505  arpc1a.L; actin-related protein 2/3 complex subunit 1A-B [KO:K05757]
108701573  pdgfa.L; platelet-derived growth factor subunit A-like isoform X2 [KO:K04359]
108701717  [KO:K05718]
108701718  [KO:K12758]
108701729  [KO:K06461]
108701763  mylkl.L; myosin light chain kinase, smooth muscle [KO:K00907] [EC:2.7.11.18]
108701919  [KO:K06461]
108702240  mylk.S; LOW QUALITY PROTEIN: myosin light chain kinase, smooth muscle-like [KO:K00907] [EC:2.7.11.18]
108702534  itga3.S; integrin alpha-3 isoform X2 [KO:K06482]
108702704  baiap2.S; brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1 [KO:K05627]
108702819  itgb4.S; integrin beta-4 isoform X2 [KO:K06525]
108702890  itgb5.S; integrin beta-5 isoform X1 [KO:K06588]
108702900  mras.S; ras-related protein M-Ras [KO:K07831]
108702994  itga6.S; integrin alpha-6 isoform X1 [KO:K06485]
108703022  nckap1.S; nck-associated protein 1-like isoform X1 [KO:K05750]
108703086  actb.S; actin, cytoplasmic 1 [KO:K05692]
108704012  raf1.L; RAF proto-oncogene serine/threonine-protein kinase-like [KO:K04366] [EC:2.7.11.1]
108704031  fgd3.L; FYVE, RhoGEF and PH domain-containing protein 3 [KO:K05722]
108704179  [KO:K06269] [EC:3.1.3.16]
108704358  chrm2.L; muscarinic acetylcholine receptor M2 [KO:K04130]
108704399  fgd3.S; FYVE, RhoGEF and PH domain-containing protein 3-like isoform X1 [KO:K05722]
108704666  [KO:K02085]
108704799  fgd1.L; FYVE, RhoGEF and PH domain-containing protein 1 isoform X1 [KO:K05720]
108705008  [KO:K05730]
108705016  [KO:K27976]
108705108  limk2.S; LIM domain kinase 2 [KO:K05744] [EC:2.7.11.1]
108705398  itga1.S; integrin alpha-1 [KO:K06480]
108706592  pdgfra.S; platelet-derived growth factor receptor alpha-like [KO:K04363] [EC:2.7.10.1]
108706603  fgf20.S; fibroblast growth factor 20 [KO:K04358]
108706647  pdgfc.S; platelet-derived growth factor C [KO:K05450]
108706695  fgf2.S; fibroblast growth factor 2-like [KO:K18497]
108706884  pik3r2.S; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
108707215  apc.S; adenomatous polyposis coli homolog isoform X1 [KO:K02085]
108707268  f2r.S; proteinase-activated receptor 1-like [KO:K03914]
108707456  myl10.L; myosin regulatory light chain 2B, cardiac muscle isoform isoform X1 [KO:K12756]
108707572  [KO:K05450]
108707573  rdx.L; radixin [KO:K05762]
108707884  tiam1.L; T-lymphoma invasion and metastasis-inducing protein 1 isoform X1 [KO:K05731]
108707931  itgae.L; integrin alpha-E isoform X1 [KO:K06524]
108707948  git1.L; ARF GTPase-activating protein GIT1 isoform X1 [KO:K05737]
108708100  slc9a1.L; sodium/hydrogen exchanger 1 isoform X1 [KO:K05742]
108708153  ppp1r12b.L; protein phosphatase 1 regulatory subunit 12B [KO:K12329]
108708458  arhgef7.L; rho guanine nucleotide exchange factor 7 isoform X4 [KO:K13710]
108708510  diaph3.L; protein diaphanous homolog 3 isoform X1 [KO:K05745]
108708515  rgcc.L; regulator of cell cycle RGCC [KO:K26108]
108708560  itga7.L; integrin alpha-7 isoform X2 [KO:K06583]
108708590  pip4k2c.L; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform X1 [KO:K00920] [EC:2.7.1.149]
108708630  nckap1l.L; nck-associated protein 1-like [KO:K05750]
108708650  itgb7.L; integrin beta-7 [KO:K06590]
108708716  [KO:K05769]
108708721  [KO:K04358]
108708849  [KO:K05766] [EC:3.1.3.16 3.1.3.48]
108708991  itga7.S; integrin alpha-7 isoform X1 [KO:K06583]
108709092  [KO:K12756]
108709173  git1.S; ARF GTPase-activating protein GIT1 isoform X2 [KO:K05737]
108709319  limk1.S; LIM domain kinase 1-like isoform X1 [KO:K05743] [EC:2.7.11.1]
108709342  crk.S; adapter molecule crk-like isoform X1 [KO:K04438]
108709436  rhoc.S; rho-related GTP-binding protein RhoA-D [KO:K04513]
108709524  wasf2.S; wiskott-Aldrich syndrome protein family member 2 [KO:K05748]
108709680  [KO:K05764]
108709728  [KO:K05749]
108709967  [KO:K05769]
108709984  pdgfd.S; platelet-derived growth factor D [KO:K05450]
108710179  egf.L; pro-epidermal growth factor [KO:K04357]
108710189  fgf23.2.L; fibroblast growth factor 23 [KO:K22428]
108710561  fgf23.1.L; fibroblast growth factor 23 [KO:K22428]
108710781  fgf6.L; fibroblast growth factor 6 [KO:K04358]
108710882  diaph1.L; protein diaphanous homolog 1 isoform X3 [KO:K05740]
108711109  ppp1r12a.L; protein phosphatase 1 regulatory subunit 12A isoform X3 [KO:K06270]
108711510  itga11.L; integrin alpha-11 [KO:K06587]
108711685  lpar2.L; lysophosphatidic acid receptor 2 [KO:K04291]
108712206  [KO:K00889] [EC:2.7.1.68]
108712265  fgf23.2.S; fibroblast growth factor 23 [KO:K22428]
108712444  fgf23.1.S; fibroblast growth factor 23 [KO:K22428]
108712445  fgf6.S; fibroblast growth factor 6 [KO:K04358]
108712468  apc2.L; adenomatous polyposis coli protein 2 isoform X1 [KO:K02085]
108712499  fgf1.S; fibroblast growth factor 1 [KO:K18496]
108712520  krasl.S; GTPase KRas isoform X1 [KO:K07827]
108712545  chrm2.S; muscarinic acetylcholine receptor M2 [KO:K04130]
108712643  pdgfrb.S; platelet-derived growth factor receptor beta [KO:K05089] [EC:2.7.10.1]
108712731  myl7.S; myosin regulatory light chain 2, atrial isoform [KO:K12754]
108712802  map2k1.S; dual specificity mitogen-activated protein kinase kinase 1-like [KO:K04368] [EC:2.7.12.2]
108712902  fgf7.S; fibroblast growth factor 7 [KO:K04358]
108713027  pik3r2.L; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
108713094  wasl.S; neural Wiskott-Aldrich syndrome protein isoform X2 [KO:K23612]
108713205  fgf22.L; fibroblast growth factor 22 [KO:K04358]
108713303  diaph1.S; protein diaphanous homolog 1 [KO:K05740]
108713768  chrm4.L; muscarinic acetylcholine receptor M4-like [KO:K04132]
108713841  [KO:K06270]
108713873  chrm1.L; muscarinic acetylcholine receptor M1 [KO:K04129]
108714133  [KO:K00907] [EC:2.7.11.18]
108714245  c8b.L; complement component C8 beta chain [KO:K03998]
108714432  vav3.L; guanine nucleotide exchange factor VAV3 isoform X2 [KO:K05730]
108714525  pdgfb.L; platelet-derived growth factor subunit B isoform X1 [KO:K17386]
108714705  [KO:K05755]
108715066  fgf19.S; fibroblast growth factor 19 [KO:K22603]
108715175  chrm1.S; muscarinic acetylcholine receptor M1 [KO:K04129]
108715193  [KO:K06270]
108715244  chrm4.S; muscarinic acetylcholine receptor M4 isoform X1 [KO:K04132]
108715251  fgf3.S; fibroblast growth factor 3 S homeolog precursor [KO:K04358]
108715363  bcar1.S; breast cancer anti-estrogen resistance protein 1 isoform X1 [KO:K05726]
108715487  [KO:K00907] [EC:2.7.11.18]
108715518  gng12.S; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
108715579  ssh1.L; protein phosphatase Slingshot homolog 1 isoform X1 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
108715695  vav3.S; guanine nucleotide exchange factor VAV3 isoform X2 [KO:K05730]
108715797  [KO:K07860]
108715815  rhoa.S; transforming protein RhoA [KO:K04513]
108716013  pxn.L; paxillin isoform X1 [KO:K05760]
108716398  pak5.L; serine/threonine-protein kinase PAK 5 [KO:K05736] [EC:2.7.11.1]
108716609  dstn.L; cofilin-1 [KO:K05765]
108716660  sos1.L; son of sevenless homolog 1 [KO:K03099]
108716738  chrm3.L; muscarinic acetylcholine receptor M3 [KO:K04131]
108716834  wasf1.L; wiskott-Aldrich syndrome protein family member 1 isoform X1 [KO:K05753]
108717108  arhgef4.L; rho guanine nucleotide exchange factor 4 isoform X2 [KO:K05769]
108717120  pik3cb.L; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
108717139  pak2.L; serine/threonine-protein kinase PAK 2 [KO:K04410] [EC:2.7.11.1]
108717190  cyria.L; CYFIP-related Rac1 interactor A isoform X1 [KO:K27976]
108717462  [KO:K05759]
108717671  ppp1cb.S; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
108717760  pak5.S; serine/threonine-protein kinase PAK 5 [KO:K05736] [EC:2.7.11.1]
108717808  sos1.S; son of sevenless homolog 1 [KO:K03099]
108717898  iqgap2.L; ras GTPase-activating-like protein IQGAP2 isoform X1 [KO:K05767]
108718071  kng1.S; T-kininogen 1 isoform X3 [KO:K03898]
108718090  pik3ca.S; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
108718177  arhgef4.S; uncharacterized protein arhgef4.S isoform X1 [KO:K05769]
108718190  pik3cb.S; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
108718266  pfn4.S; profilin-4 [KO:K05759]
108718392  [KO:K06480]
108718395  fgf10.L; fibroblast growth factor 10 [KO:K04358]
108718800  pip4k2a.L; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
108718824  itga8.L; integrin alpha-8 [KO:K06584]
108718853  [KO:K05768]
108718868  itgb8.L; integrin beta-8 [KO:K06591]
108719000  itga9.L; integrin alpha-9 [KO:K06585]
108719107  mylk4.L; serine/threonine-protein kinase pakF isoform X1 [KO:K00907] [EC:2.7.11.18]
108719215  rock1.L; rho-associated protein kinase 1 [KO:K04514] [EC:2.7.11.39]
108719676  [KO:K05768]
108719862  pip4k2a.S; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [KO:K00920] [EC:2.7.1.149]
108719885  itga8.S; integrin alpha-8 [KO:K06584]
108719918  itgb8.S; integrin beta-8 [KO:K06591]
108719997  egfr.S; epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
108720081  mylk4.S; myosin light chain kinase 3 isoform X1 [KO:K00907] [EC:2.7.11.18]
121393057  [KO:K05717]
121396914  [KO:K26108]
373569  fgf10.S; fibroblast growth factor 10 S homeolog [KO:K04358]
373591  lpar1.L; lysophosphatidic acid receptor 1-B [KO:K04289]
373647  src.S; tyrosine-protein kinase Src-1 [KO:K05704] [EC:2.7.10.2]
373657  itga3.L; integrin alpha-3 [KO:K06482]
373669  fgf3.L; fibroblast growth factor 3 precursor [KO:K04358]
373743  itga2.L; integrin alpha-2 [KO:K06481]
373752  pik3ca.L; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
373770  vcl.S; vinculin isoform X2 [KO:K05700]
378493  pak3.L; serine/threonine-protein kinase PAK 3 [KO:K05733] [EC:2.7.11.1]
378526  f2r.L; proteinase-activated receptor 1 precursor [KO:K03914]
378559  itga11.S; integrin alpha-11 [KO:K06587]
378562  fgf9.S; fibroblast growth factor 9 [KO:K04358]
378586  fgf4.L; fibroblast growth factor 4A precursor [KO:K04358]
378587  fgf4.S; fibroblast growth factor 4B precursor [KO:K04358]
378686  itgb6.L; integrin beta-6 isoform X1 [KO:K06589]
378695  ins.L; insulin-2 precursor [KO:K04526]
378696  ins.S; insulin-1 precursor [KO:K04526]
379055  cdc42.L; cell division cycle 42 L homeolog [KO:K04393]
379126  c6.2.L; complement C6, gene 2 L homeolog precursor [KO:K03995]
379172  cfl1.S; cofilin-1-B [KO:K05765]
379258  cfl1.L; cofilin-1-A [KO:K05765]
379282  dstn.S; destrin, actin depolymerizing factor S homeolog [KO:K05765]
379326  rhoc.L; ras homolog family member C L homeolog [KO:K04513]
379403  lpar1.S; lysophosphatidic acid receptor 1-A isoform X1 [KO:K04289]
379416  rhoa.L; ras homolog family member A L homeolog [KO:K04513]
379504  c9.L; complement C9 L homeolog precursor [KO:K04000]
379646  vav2.S; vav guanine nucleotide exchange factor 2 S homeolog [KO:K05730]
379708  itgb2.L; integrin beta-2 precursor [KO:K06464]
379722  XB5901009.L; uncharacterized protein LOC379722 [KO:K27976]
379746  arpc3.L; actin-related protein 2/3 complex subunit 3-B [KO:K05756]
379783  akt2.L; RAC-beta serine/threonine-protein kinase A [KO:K04456] [EC:2.7.11.1]
379845  arpc1a.S; actin-related protein 2/3 complex subunit 1A-A [KO:K05757]
379914  ppp1ca.L; protein phosphatase 1, catalytic subunit, alpha isozyme L homeolog [KO:K06269] [EC:3.1.3.16]
379991  map2k1.L; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
380007  mylc2a; myosin light chain, regulatory A [KO:K12754]
380084  actr3.S; actin-related protein 3-A [KO:K18584]
380108  arpc1b.L; actin-related protein 2/3 complex subunit 1B-A [KO:K05757]
380133  rhoa.2.S; ras homolog gene family, member A, gene 2 S homeolog [KO:K04513]
380245  pdgfra.L; platelet-derived growth factor receptor alpha precursor [KO:K04363] [EC:2.7.10.1]
380373  cxcr4.S; C-X-C chemokine receptor type 4-B [KO:K04189]
380430  src.L; tyrosine-protein kinase Src-2 [KO:K05704] [EC:2.7.10.2]
380472  myl12b.L; myosin light chain 12B L homeolog [KO:K12757]
380475  pfn2.L; profilin 2 L homeolog [KO:K05759]
380582  cyrib.L; uncharacterized protein LOC380582 [KO:K27976]
380598  ppp1cc.S; serine/threonine-protein phosphatase PP1-gamma catalytic subunit B [KO:K06269] [EC:3.1.3.16]
394289  rock2.L; Rho-associated, coiled-coil containing protein kinase 2 L homeolog [KO:K17388] [EC:2.7.11.39]
394360  abi2.S; abl-interactor 2 S homeolog [KO:K05751]
394366  itga5.L; integrin alpha-5 precursor [KO:K06484]
397696  limk1.L; LIM domain kinase 1 [KO:K05743] [EC:2.7.11.1]
397699  itgb3.L; integrin beta-3 isoform X1 [KO:K06493]
397701  fgfr4.L; fibroblast growth factor receptor 4 L homeolog precursor [KO:K05095] [EC:2.7.10.1]
397744  fn1.S; fibronectin precursor [KO:K05717]
397755  itgb1.L; integrin beta-1-A precursor [KO:K05719]
397765  pdgfa.S; platelet-derived growth factor subunit A precursor [KO:K04359]
397767  ppp1cc.L; serine/threonine-protein phosphatase PP1-gamma catalytic subunit A [KO:K06269] [EC:3.1.3.16]
397771  kras.L; kirsten rat sarcoma viral oncogene homolog L homeolog [KO:K07827]
397782  xfgfra2; fibroblast growth factor receptor precursor [KO:K04362] [EC:2.7.10.1]
397785  mapk1.L; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
397826  pxn.S; paxillin S homeolog [KO:K05760]
397839  itga4.S; integrin alpha-4 precursor [KO:K06483]
397842  itga5.S; integrin alpha-5-like isoform X1 [KO:K06484]
397857  raf1.S; RAF proto-oncogene serine/threonine-protein kinase [KO:K04366] [EC:2.7.11.1]
397895  gsn.S; gelsolin [KO:K05768]
397917  slc9a1.S; solute carrier family 9 member 1 S homeolog [KO:K05742]
397924  mos.L; serine/threonine-protein kinase mos [KO:K04367] [EC:2.7.11.1]
397985  itga6.L; integrin alpha-6 isoform X1 [KO:K06485]
397997  itgav.L; integrin subunit alpha V L homeolog precursor [KO:K06487]
398083  myh9.L; myosin-9 [KO:K10352]
398126  pak1.S; p21-activated kinase 1 [KO:K04409] [EC:2.7.11.1]
398181  fgfr4.S; fibroblast growth factor receptor 4 precursor [KO:K05095] [EC:2.7.10.1]
398224  pak4.L; p21-activated kinase 4 [KO:K05734] [EC:2.7.11.1]
398298  limk2.L; LIM domain kinase 2 L homeolog [KO:K05744] [EC:2.7.11.1]
398459  actb.L; actin, cytoplasmic 1 [KO:K05692]
398588  iqgap2.S; IQ motif containing GTPase activating protein 2 S homeolog [KO:K05767]
398589  iqgap1.L; IQ motif containing GTPase activating protein 1 L homeolog [KO:K16848]
398618  ssh3.L; protein phosphatase Slingshot homolog [KO:K05766] [EC:3.1.3.16 3.1.3.48]
398635  pfn1.S; uncharacterized protein LOC398635 [KO:K05759]
398687  pip5k1c.S; phosphatidylinositol-4-phosphate 5-kinase, type I, gamma S homeolog [KO:K00889] [EC:2.7.1.68]
398710  arhgef12.S; Rho guanine nucleotide exchange factor 12 S homeolog [KO:K07532]
398719  myh9.S; myosin-9 [KO:K10352]
398756  bcar1.L; BCAR1, Cas family scaffold protein L homeolog [KO:K05726]
398782  MGC68680; uncharacterized protein LOC398782 [KO:K04409] [EC:2.7.11.1]
398892  araf.L; A-Raf proto-oncogene, serine/threonine kinase L homeolog [KO:K08845] [EC:2.7.11.1]
398941  insrr.L; insulin receptor related receptor L homeolog precursor [KO:K05086] [EC:2.7.10.1]
398951  crk.L; adapter molecule crk [KO:K04438]
398973  braf.S; B-Raf [KO:K04365] [EC:2.7.11.1]
398985  mapk1.S; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
399030  cxcl12.L; stromal cell-derived factor 1 isoform beta precursor [KO:K10031]
399042  brk1.L; probable protein BRICK1-A [KO:K05752]
399056  araf.S; A-Raf proto-oncogene, serine/threonine kinase S homeolog [KO:K08845] [EC:2.7.11.1]
399090  pak2.S; p21-activated kinase 2 [KO:K04410] [EC:2.7.11.1]
399105  fgf20.L; fibroblast growth factor 20 L homeolog [KO:K04358]
399170  akt1.S; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
399183  fgf8.L; fibroblast growth factor 8 L homeolog precursor [KO:K04358]
399202  pik3r1.S; phosphatidylinositol 3-kinase regulatory subunit alpha [KO:K02649]
399251  mylpf.L; myosin light chain, phosphorylatable, fast skeletal muscle L homeolog [KO:K12758]
399266  myh10.S; myosin, heavy chain 10, non-muscle S homeolog [KO:K10352]
399286  ptk2.L; focal adhesion kinase 1 [KO:K05725] [EC:2.7.10.2]
399325  fgfr2.L; fibroblast growth factor receptor 2 precursor [KO:K05093] [EC:2.7.10.1]
399347  fgfr3.S; fibroblast growth factor receptor 3 [KO:K05094] [EC:2.7.10.1]
399379  rac3.S; Rac family small GTPase 3 S homeolog [KO:K04392]
399394  pip4k2b.L; phosphatidylinositol-5-phosphate 4-kinase, type II, beta L homeolog [KO:K00920] [EC:2.7.1.149]
399406  hras.L; Harvey rat sarcoma viral oncogene homolog L homeolog [KO:K02833]
399422  actn1.L; actinin alpha 1 L homeolog [KO:K05699]
399438  tmsb4x.L; thymosin beta-4 [KO:K05764]
399443  itgb1.S; integrin beta-1-B precursor [KO:K05719]
399444  fgfr1.L; fibroblast growth factor receptor 1 L homeolog precursor [KO:K04362] [EC:2.7.10.1]
399446  nras.L; GTPase NRas [KO:K07828]
399455  apc.L; adenomatous polyposis coli homolog [KO:K02085]
414569  crkl.S; uncharacterized protein LOC414569 [KO:K04438]
414634  arhgap35.L; rho GTPase-activating protein 35 [KO:K05732]
431885  actn1.S; uncharacterized protein LOC431885 [KO:K05699]
431898  wasl.L; WASP like actin nucleation promoting factor L homeolog [KO:K23612]
432072  ptk2.S; uncharacterized protein LOC432072 [KO:K05725] [EC:2.7.10.2]
432109  arpc2.S; actin-related protein 2/3 complex subunit 2-B [KO:K05758]
432172  akt2.S; RAC-beta serine/threonine-protein kinase B [KO:K04456] [EC:2.7.11.1]
432189  c7.S; complement C7 S homeolog precursor [KO:K03996]
432346  c6.1.L; complement C6, gene 1 L homeolog precursor [KO:K03995]
443585  [KO:K10352]
443652  f2.L; coagulation factor II, thrombin L homeolog precursor [KO:K01313] [EC:3.4.21.5]
443741  actr2.L; actin-related protein 2-B [KO:K17260]
443852  ppp1cb.L; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
443897  cyfip2.S; cytoplasmic FMR1-interacting protein 2 [KO:K05749]
443932  mras.L; muscle RAS oncogene homolog L homeolog [KO:K07831]
443964  pik3r1.L; phosphoinositide-3-kinase regulatory subunit 1 L homeolog [KO:K02649]
443975  c8a.L; complement C8 alpha chain L homeolog precursor [KO:K03997]
444086  enah.L; ENAH, actin regulator L homeolog [KO:K05746]
444184  rac2.L; Rac family small GTPase 2 L homeolog [KO:K07860]
444191  rras2.S; RAS related 2 S homeolog [KO:K07830]
444238  pip5k1b.L; phosphatidylinositol-4-phosphate 5-kinase, type I, beta L homeolog [KO:K00889] [EC:2.7.1.68]
444264  arpc1b.S; actin-related protein 2/3 complex subunit 1B-B [KO:K05757]
444424  arhgef7.S; Rho guanine nucleotide exchange factor 7 S homeolog [KO:K13710]
444518  scin.L; scinderin L homeolog [KO:K05768]
444594  arpc5l.S; actin related protein 2/3 complex subunit 5-like S homeolog [KO:K05754]
444686  fgf1.L; fibroblast growth factor 1 [KO:K18496]
444717  wasf1.S; WASP family member 1 S homeolog [KO:K05753]
445857  [KO:K16848]
446221  enah.S; ENAH, actin regulator S homeolog [KO:K05746]
446228  cyfip1.L; cytoplasmic FMR1-interacting protein 1 isoform X1 [KO:K05749]
446352  f2.S; coagulation factor II, thrombin S homeolog precursor [KO:K01313] [EC:3.4.21.5]
446423  itgb5.L; integrin subunit beta 5 L homeolog precursor [KO:K06588]
446537  arpc5l.L; actin-related protein 2/3 complex subunit 5-B [KO:K05754]
446786  pik3r3.S; phosphoinositide-3-kinase regulatory subunit 3 S homeolog [KO:K02649]
446826  vav1.L; vav guanine nucleotide exchange factor 1 L homeolog [KO:K05730]
446851  myl9.L; myosin light chain 9 L homeolog [KO:K12755]
446865  actn4.S; actinin alpha 4 S homeolog [KO:K05699]
447131  myl2.S; myosin light chain 2 S homeolog [KO:K10351]
447216  ezr.L; ezrin L homeolog [KO:K08007]
447268  braf.L; B-Raf proto-oncogene, serine/threonine kinase L homeolog [KO:K04365] [EC:2.7.11.1]
447269  rgcc.S; regulator of cell cycle S homeolog [KO:K26108]
447274  arpc5.L; actin-related protein 2/3 complex subunit 5-A [KO:K05754]
447419  crkl.L; v-crk avian sarcoma virus CT10 oncogene homolog-like L homeolog [KO:K04438]
447460  lpar2.S; lysophosphatidic acid receptor 2 S homeolog [KO:K04291]
447594  pik3r3.L; phosphoinositide-3-kinase regulatory subunit 3 L homeolog [KO:K02649]
447704  myl9.S; myosin light chain 9 S homeolog [KO:K12755]
447745  [KO:K05754]
493575  pdgfb.S; platelet-derived growth factor subunit B [KO:K17386]
494639  arpc4.S; actin-related protein 2/3 complex subunit 4 [KO:K05755]
494653  nckap1.L; nck-associated protein 1 [KO:K05750]
494833  kng1.L; kininogen 1 L homeolog precursor [KO:K03898]
494995  cfl2.L; cofilin-2 [KO:K05765]
495051  itga2b.2.L; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41), gene 2 L homeolog precursor [KO:K06476]
495286  myh11.L; myosin-11 isoform X2 [KO:K10352]
496028  pip4k2c.S; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
496349  gna13.S; uncharacterized protein LOC496349 [KO:K04639]
595043  gng12.L; guanine nucleotide binding protein (G protein), gamma 12 L homeolog [KO:K04347]
724072  egfr.L; epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
733146  wasf2.L; wiskott-Aldrich syndrome protein family member 2 [KO:K05748]
733147  rdx.S; radixin [KO:K05762]
733200  ppp1r12a.S; protein phosphatase 1 regulatory subunit 12A isoform X3 [KO:K06270]
734239  actr2.S; actin-related protein 2-A [KO:K17260]
734382  rac1.L; Rac family small GTPase 1 L homeolog [KO:K04392]
734697  fgf7.L; fibroblast growth factor 7 L homeolog [KO:K04358]
734918  actg1.L; actin, cytoplasmic type 8 [KO:K05692]
734930  actn4.L; uncharacterized protein LOC734930 [KO:K05699]
735107  msn.L; moesin isoform X2 [KO:K05763]
735169  pfn1.L; profilin 1 L homeolog [KO:K05759]
735176  tiam1.S; T cell lymphoma invasion and metastasis S homeolog [KO:K05731]
779088  [KO:K07830]
779237  cyria.S; uncharacterized protein LOC779237 [KO:K27976]
779370  fgfr3.L; fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog [KO:K05094] [EC:2.7.10.1]
779406  arpc2.L; actin-related protein 2/3 complex subunit 2-A [KO:K05758]
779407  lpar4.L; lysophosphatidic acid receptor 4 L homeolog [KO:K04275]
Compound
C00681  1-Acyl-sn-glycerol 3-phosphate
C01996  Acetylcholine
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:14744429
  Authors
Burridge K, Wennerberg K.
  Title
Rho and Rac take center stage.
  Journal
Cell 116:167-79 (2004)
DOI:10.1016/S0092-8674(04)00003-0
Reference
PMID:11082269
  Authors
Schmitz AA, Govek EE, Bottner B, Van Aelst L.
  Title
Rho GTPases: signaling, migration, and invasion.
  Journal
Exp Cell Res 261:1-12 (2000)
DOI:10.1006/excr.2000.5049
Reference
PMID:11152757
  Authors
Takai Y, Sasaki T, Matozaki T.
  Title
Small GTP-binding proteins.
  Journal
Physiol Rev 81:153-208 (2001)
DOI:10.1152/physrev.2001.81.1.153
Reference
PMID:12700767
  Authors
Pollard TD.
  Title
The cytoskeleton, cellular motility and the reductionist agenda.
  Journal
Nature 422:741-5 (2003)
DOI:10.1038/nature01598
Reference
PMID:14657486
  Authors
Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR.
  Title
Cell migration: integrating signals from front to back.
  Journal
Science 302:1704-9 (2003)
DOI:10.1126/science.1092053
Reference
PMID:11082272
  Authors
Sastry SK, Burridge K.
  Title
Focal adhesions: a nexus for intracellular signaling and cytoskeletal dynamics.
  Journal
Exp Cell Res 261:25-36 (2000)
DOI:10.1006/excr.2000.5043
Reference
PMID:10574699
  Authors
Fukata M, Nakagawa M, Kuroda S, Kaibuchi K.
  Title
Cell adhesion and Rho small GTPases.
  Journal
J Cell Sci 112 ( Pt 24):4491-500 (1999)
Related
pathway
xla04010  MAPK signaling pathway
xla04510  Focal adhesion
xla04520  Adherens junction
KO pathway
ko04810   

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