KEGG   PATHWAY: xtr05132
Entry
xtr05132                    Pathway                                
Name
Salmonella infection - Xenopus tropicalis (tropical clawed frog)
Description
Salmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid fever and bacteremia. The common disease-causing Salmonella species in human is a single species, Salmonella enterica, which has numerous serovars.
Following intestinal colonization Salmonella inject effector proteins into the host cells using a type III secretion system (T3SS), T3SS1. Then a small group of effector proteins induce rearrangement of the actin cytoskeleton resulting in membrane ruffles and rapid internalization of the bacteria.The T3SS2 is responsible for translocating effector proteins that direct Salmonella-containing vacuole (SCV) maturation. The majority of the bacteria are known to survive and replicate in SCV.
Class
Human Diseases; Infectious disease: bacterial
Pathway map
xtr05132  Salmonella infection
xtr05132

Organism
Xenopus tropicalis (tropical clawed frog) [GN:xtr]
Gene
100492477  podxl; podocalyxin [KO:K06817]
100493434  ptprc; receptor-type tyrosine-protein phosphatase C [KO:K06478] [EC:3.1.3.48]
493430  rab5a; ras-related protein Rab-5A [KO:K07887]
448258  rab5b; ras-related protein Rab-5B [KO:K07888]
594964  rab5d; muscle RAS oncogene homolog isoform 2 [KO:K07888]
594914  rab5c; ras-related protein Rab-5C [KO:K07889]
100485933  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
493388  rab7a; ras-related protein Rab-7a [KO:K07897]
394774  MGC75872; uncharacterized protein LOC394774 [KO:K07897]
100124979  rab7b; ras-related protein Rab-7b [KO:K07898]
100491541  plekhm1; pleckstrin homology domain-containing family M member 1 [KO:K23282]
100101673  vps11; vacuolar protein sorting-associated protein 11 homolog [KO:K20179]
448414  vps16; vacuolar protein sorting-associated protein 16 homolog [KO:K20180]
100158548  vps18; vacuolar protein sorting-associated protein 18 homolog [KO:K20181]
549689  vps33a; vacuolar protein sorting-associated protein 33A [KO:K20182]
100216188  vps39; vam6/Vps39-like protein [KO:K20183]
100489726  vps41; vacuolar protein sorting-associated protein 41 homolog isoform X2 [KO:K20184]
100127814  rilp; rab-interacting lysosomal protein [KO:K13883]
100380107  dync2h1; cytoplasmic dynein 2 heavy chain 1 [KO:K10414]
407935  dync1i2; cytoplasmic dynein 1 intermediate chain 2 [KO:K10415]
100127187  dync1i1; cytoplasmic dynein 1 intermediate chain 1 [KO:K10415]
779754  dync1li1; cytoplasmic dynein 1 light intermediate chain 1 [KO:K10416]
100498465  dync1li2; cytoplasmic dynein 1 light intermediate chain 2 isoform X1 [KO:K10416]
101734949  dync2li1; cytoplasmic dynein 2 light intermediate chain 1 [KO:K10417]
448652  dynll1; dynein light chain 1, cytoplasmic [KO:K10418]
100038056  dynll2; dynein light chain 2, cytoplasmic [KO:K10418]
549149  dynlrb2; dynein light chain roadblock-type 2 [KO:K10419]
100101695  dynlrb1; dynein light chain roadblock-type 1 [KO:K10419]
496911  dynlt1; dynein light chain Tctex-type 1 [KO:K10420]
101732306  dynlt3; dynein light chain Tctex-type 3 [KO:K10420]
447948  dctn1; dynactin subunit 1 isoform X8 [KO:K04648]
548423  dctn2; dynactin subunit 2 [KO:K10424]
100125086  dctn3; uncharacterized protein LOC100125086 [KO:K10425]
595065  dctn4; dynactin subunit 4 [KO:K10426]
496622  dctn5; dynactin subunit 5 [KO:K10427]
733845  dctn6; dynactin subunit 6 [KO:K10428]
100101796  actr1a; alpha-centractin [KO:K16575]
496410  actr10; actin-related protein 10 [KO:K16576]
394675  tuba1c; tubulin alpha 1c [KO:K07374]
394734  tuba1cl.3; tubulin alpha chain 1c like [KO:K07374]
407878  tubal3.1; tubulin alpha chain like 3 [KO:K07374]
548558  tubal3.2; tubulin alpha chain like 3 [KO:K07374]
548688  tuba3c; tubulin, alpha 3c [KO:K07374]
549448  tuba4b; tubulin alpha chain [KO:K07374]
100038108  tuba1b; 1 [KO:K07374]
100038123  tuba1a; tubulin alpha-1A chain [KO:K07374]
100497157  tubulin alpha-1A chain [KO:K07374]
100037894  tuba8; tubulin alpha-8 chain [KO:K07374]
100144986  tuba1l; LOW QUALITY PROTEIN: tubulin alpha-8 chain [KO:K07374]
100486465  tuba1al; LOW QUALITY PROTEIN: tubulin alpha-8 chain [KO:K07374]
100490289  tuba1cl.1; tubulin alpha-1A chain [KO:K07374]
100497528  tuba1cl.2; tubulin alpha-1A chain [KO:K07374]
779904  tubb4b; tubulin beta 4B class IVb [KO:K07375]
448742  tubb; tubulin beta chain [KO:K07375]
493418  tubb6; tubulin beta-6 chain [KO:K07375]
394889  tubb2b; tubulin beta 2B class IIb [KO:K07375]
395045  tubb3; tubulin beta-3 chain [KO:K07375]
394927  tubb4a; tubulin beta-4A chain [KO:K07375]
101730558  tubb1; tubulin beta-1 chain isoform X1 [KO:K07375]
394587  arl8a; ADP-ribosylation factor-like protein 8A [KO:K07955]
100492504  arl8b; ADP-ribosylation factor-like protein 8B [KO:K07955]
548865  arl10b; ADP-ribosylation factor-like 10B [KO:K07955]
100380102  plekhm2; pleckstrin homology domain-containing family M member 2 isoform X1 [KO:K15348]
100124766  kif5a; kinesin heavy chain [KO:K10396]
100038146  kif5b; kinesin-1 heavy chain [KO:K10396]
100493873  kif5c; kinesin heavy chain [KO:K10396]
550001  klc1; kinesin light chain 1 [KO:K10407]
100216226  uncharacterized protein LOC100216226 [KO:K10407]
100124747  acbd3; Golgi resident protein GCP60 [KO:K23935]
549402  rhoa.2; ras homolog gene family, member A, gene 2 [KO:K04513]
549323  rhoc; rho-related GTP-binding protein RhoC [KO:K04513]
448080  rhoa; transforming protein RhoA [KO:K04513]
493477  m6pr; cation-dependent mannose-6-phosphate receptor precursor [KO:K10089]
780093  rab9a; ras-related protein Rab-9A [KO:K07899]
780136  rab9b; ras-related protein Rab-9B [KO:K07900]
100158612  gcc2; GRIP and coiled-coil domain-containing protein 2 [KO:K20282]
100145797  stx10; syntaxin-10 [KO:K23937]
548852  pfn2; profilin-2 [KO:K05759]
100495970  pfn4; profilin-4 [KO:K05759]
100170559  pfn1; profilin 1 [KO:K05759]
779840  flna; filamin-A [KO:K04437]
549650  exoc7; exocyst complex component 7 [KO:K07195]
550096  exoc5; exocyst complex component 5 [KO:K19984]
100379737  exoc4; exocyst complex component 4 isoform X1 [KO:K06111]
100491449  exoc2; exocyst complex component 2 [KO:K17637]
548669  rala; ras-related protein Ral-A [KO:K07834]
394957  actg1; actin, cytoplasmic 2 [KO:K05692]
407952  actb; actin, cytoplasmic 1 [KO:K05692]
496921  s100a10; S100 calcium binding protein A10 [KO:K17274]
394517  anxa2; annexin A2 [KO:K17092]
733715  ahnak; neuroblast differentiation-associated protein AHNAK isoform X1 [KO:K23934]
101730314  ahnak2; titin [KO:K23934]
100125013  rhoj; rho-related GTP-binding protein RhoJ isoform X2 [KO:K07864]
100495357  arhgef26; rho guanine nucleotide exchange factor 26 [KO:K13744]
100216282  rhogl; ras homolog gene family, member G (rho G) like [KO:K07863]
100489878  rhog; rho-related GTP-binding protein RhoG [KO:K07863]
100380096  elmo1; engulfment and cell motility protein 1 isoform X1 [KO:K12366]
493485  elmo2; engulfment and cell motility protein 2 [KO:K18985]
100493965  rock2; rho-associated protein kinase 2 isoform X3 [KO:K17388] [EC:2.7.11.1]
100135705  myl2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
100135145  myl7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
100124811  myl9; myosin regulatory light polypeptide 9 [KO:K12755]
100170437  myl10; myosin regulatory light chain 10 [KO:K12756]
448060  myl12b; myosin light chain 12B [KO:K12757]
394763  mylpf; myosin regulatory light chain 2, skeletal muscle isoform [KO:K12758]
493389  cdc42; cell division control protein 42 homolog isoform 1 [KO:K04393]
448118  rac1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
100379683  nckap1; nck-associated protein 1 isoform X3 [KO:K05750]
100491829  nckap1l; nck-associated protein 1-like [KO:K05750]
100126215  cyfip2; cytoplasmic FMR1-interacting protein 2 [KO:K05749]
101734874  cyfip1; cytoplasmic FMR1-interacting protein 1 isoform X1 [KO:K05749]
493216  abi1; abl interactor 1 [KO:K23649]
548748  brk1; protein BRICK1 [KO:K05752]
779716  wasf3; wiskott-Aldrich syndrome protein family member 3 [KO:K06083]
594957  actr2; actin-related protein 2 [KO:K17260]
394999  actr3; actin-related protein 3 [KO:K18584]
448555  arpc1b; actin-related protein 2/3 complex subunit 1B [KO:K05757]
394565  arpc1a; actin-related protein 2/3 complex subunit 1A [KO:K05757]
100488540  actin-related protein 2/3 complex subunit 1A-B [KO:K05757]
448094  arpc2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
100038232  arpc3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
448127  arpc4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
549996  arpc5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
734053  arpc5l; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754]
100135731  pak1; serine/threonine-protein kinase PAK 1 isoform X1 [KO:K04409] [EC:2.7.11.1]
100495025  pak3; serine/threonine-protein kinase PAK 3 isoform X2 [KO:K05733] [EC:2.7.11.1]
493193  myo6; unconventional myosin-VI isoform X11 [KO:K10358]
780390  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
100144924  pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
100158519  pik3cg; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
100038240  pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
100496878  pik3c2g; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X1 [KO:K00923] [EC:2.7.1.154]
100379752  cyth1; cytohesin-2 [KO:K18441]
100485819  cyth4; cytohesin-4 isoform X1 [KO:K18441]
448569  cyth2; cytohesin-1 [KO:K18441]
780343  cyth3; cytohesin-3 [KO:K18441]
395051  arf6; ADP-ribosylation factor 6 [KO:K07941]
448503  arf6.2; ADP-ribosylation factor 6 [KO:K07941]
394614  arf5; ADP-ribosylation factor 1 [KO:K07937]
431681  arf1; ADP ribosylation factor 1 [KO:K07937]
448682  arl11l.1; ADP-ribosylation factor-like 11 like gene 1 [KO:K07937]
100145554  uncharacterized protein LOC100145554 [KO:K07937]
101734701  arf11l.2; ADP-ribosylation factor [KO:K07937]
116408029  ADP-ribosylation factor-like [KO:K07937]
100145698  snx9; sorting nexin-9 [KO:K17923]
496591  snx18; sorting nexin-18 [KO:K17923]
549122  snx33; sorting nexin-33 [KO:K17923]
407864  wasl; neural Wiskott-Aldrich syndrome protein [KO:K23612]
496487  dnm2; dynamin-2 [KO:K23484] [EC:3.6.5.5]
100493946  tlr6; toll-like receptor 1 [KO:K10169]
100485771  tlr2; toll-like receptor 2 type-2 [KO:K10159]
100485927  toll-like receptor 2 type-2 [KO:K10159]
100485512  toll-like receptor 2 [KO:K10159]
100487973  toll-like receptor 2 [KO:K10159]
116409470  toll-like receptor 2 [KO:K10159]
733541  tirap; toll/interleukin-1 receptor domain-containing adapter protein [KO:K05403]
100491693  uncharacterized protein LOC100491693 isoform X1 [KO:K05403]
549591  myd88; myeloid differentiation primary response protein MyD88 [KO:K04729]
100496647  toll-like receptor 5 [KO:K10168]
100489423  toll-like receptor 5 [KO:K10168]
448357  irak1; interleukin-1 receptor-associated kinase 1 [KO:K04730] [EC:2.7.11.1]
733738  irak4; interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
493524  traf6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
100101764  map3k7; mitogen-activated protein kinase kinase kinase 7 [KO:K04427] [EC:2.7.11.25]
549217  tab1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [KO:K04403]
100037849  tab2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [KO:K04404]
100495158  tab3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1 [KO:K12793]
100145270  ikbkg; NF-kappa-B essential modulator [KO:K07210]
549654  chuk; inhibitor of nuclear factor kappa-B kinase subunit alpha [KO:K04467] [EC:2.7.11.10]
448125  ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
448138  nfkbia; NF-kappa-B inhibitor alpha [KO:K04734]
100486083  nfkb1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
407869  rela; transcription factor p65 [KO:K04735]
100488164  nod1; nucleotide-binding oligomerization domain-containing protein 1 [KO:K08727]
595047  hsp90ab1; heat shock protein HSP 90-beta [KO:K04079]
780222  hsp90aa1.2; heat shock protein 90kDa alpha (cytosolic), class A member 1, gene 2 [KO:K04079]
549036  hsp90aa1.1; heat shock protein 90kDa alpha family class A member 1 [KO:K04079]
734089  hsp90b1; endoplasmin precursor [KO:K09487]
100496958  ripk2; receptor-interacting serine/threonine-protein kinase 2 isoform X1 [KO:K08846] [EC:2.7.11.1]
100158534  cse1l; exportin-2 [KO:K18423]
394800  kpna1; importin subunit alpha-5 [KO:K23940]
100380091  kpna4; importin subunit alpha-3 [KO:K23583]
548814  kpna3; importin subunit alpha-4 [KO:K23583]
394724  rps3; 40S ribosomal protein S3 [KO:K02985]
549757  hras; GTPase HRas [KO:K02833]
549871  raf1; RAF proto-oncogene serine/threonine-protein kinase [KO:K04366] [EC:2.7.11.1]
493420  map2k1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
549881  mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
448132  map2k6; dual specificity mitogen-activated protein kinase kinase 6 [KO:K04433] [EC:2.7.12.2]
448296  mapk14; mitogen-activated protein kinase 14 [KO:K04441] [EC:2.7.11.24]
549834  mapk12; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
100101766  mapk11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
100144715  mapk13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
100145045  mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
100135013  map2k4; dual specificity mitogen-activated protein kinase kinase 4 [KO:K04430] [EC:2.7.12.2]
613115  map2k7; dual specificity mitogen-activated protein kinase kinase 7 [KO:K04431] [EC:2.7.12.2]
779515  mapk10; mitogen-activated protein kinase 10 isoform 2 [KO:K04440] [EC:2.7.11.24]
100170194  mapk8; mitogen-activated protein kinase 8 [KO:K04440] [EC:2.7.11.24]
548954  fos; proto-oncogene c-Fos [KO:K04379]
100493911  jun; transcription factor AP-1 [KO:K04448]
100134991  tnf; tumor necrosis factor [KO:K03156]
100487038  il1b; interleukin-1 beta [KO:K04519]
116409784  uncharacterized protein LOC116409784 isoform X1 [KO:K04519]
100493927  il6; interleukin-6 [KO:K05405]
100498389  interleukin-8 [KO:K10030]
100498551  cxcl8; interleukin-8 [KO:K10030]
100498017  cxcl2; interleukin-8 [KO:K10030]
100498234  interleukin-8 [KO:K10030]
101730379  interleukin-8 [KO:K10030]
549712  ctnnb1; catenin beta-1 [KO:K02105]
395061  tcf7; transcription factor 7 [KO:K02620]
448107  tcf7l1; transcription factor 7-like 1 [KO:K04490]
100101719  tcf7l2; transcription factor 7-like 2 [KO:K04491]
100493178  lef1; lymphoid enhancer-binding factor 1 [KO:K04492]
395024  myc; myc proto-oncogene protein [KO:K04377]
100379847  pkn1; serine/threonine-protein kinase N1 isoform X1 [KO:K06071] [EC:2.7.11.13]
100493742  serine/threonine-protein kinase N1 [KO:K06071] [EC:2.7.11.13]
116408342  serine/threonine-protein kinase N2-like [KO:K06071] [EC:2.7.11.13]
108645541  serine/threonine-protein kinase CBK1-like [KO:K06071] [EC:2.7.11.13]
101735006  serine/threonine-protein kinase CBK1-like [KO:K06071] [EC:2.7.11.13]
116407843  serine/threonine-protein kinase N1-like [KO:K06071] [EC:2.7.11.13]
116406784  serine/threonine-protein kinase N2-like [KO:K06071] [EC:2.7.11.13]
108645367  serine/threonine-protein kinase N1 isoform X1 [KO:K06071] [EC:2.7.11.13]
116412446  cAMP-dependent protein kinase catalytic subunit-like [KO:K06071] [EC:2.7.11.13]
780359  fbxo22; F-box only protein 22 [KO:K10302]
549273  skp1; S-phase kinase-associated protein 1 [KO:K03094]
100144930  tnfrsf1a; tumor necrosis factor receptor superfamily member 1A precursor [KO:K03158]
100494415  traf2; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
100494283  tradd; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
448041  birc2; baculoviral IAP repeat-containing protein 2 [KO:K16060]
779958  ripk1; receptor-interacting serine/threonine-protein kinase 1 [KO:K02861] [EC:2.7.11.1]
448356  gapdh; glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
100493578  tnfsf10; tumor necrosis factor ligand superfamily member 10 [KO:K04721]
448240  tnfrsf10b; tumor necrosis factor receptor superfamily member 10A precursor [KO:K04722]
100379789  fadd; FAS-associated death domain protein [KO:K02373]
100495471  casp8; caspase-8 [KO:K04398] [EC:3.4.22.61]
100490493  ripk3.2; receptor-interacting serine/threonine-protein kinase 3 [KO:K08847] [EC:2.7.11.1]
100497374  receptor-interacting serine/threonine-protein kinase 4 isoform X1 [KO:K08847] [EC:2.7.11.1]
100491169  ripk3.1; receptor-interacting serine/threonine-protein kinase 3 [KO:K08847] [EC:2.7.11.1]
394793  bax; apoptosis regulator BAX [KO:K02159]
108645783  bak1; bcl-2 homologous antagonist/killer isoform X1 [KO:K14021]
493538  cyct; cytochrome c, somatic [KO:K08738]
394490  cycs; cytochrome c, testis-specific [KO:K08738]
100485267  bcl2; apoptosis regulator Bcl-2 [KO:K02161]
100151728  casp3.2; caspase-3 [KO:K02187] [EC:3.4.22.56]
100486222  casp3.1; caspase-3 isoform X2 [KO:K02187] [EC:3.4.22.56]
733553  uncharacterized protein LOC733553 [KO:K04397] [EC:3.4.22.60]
549053  casp7; caspase-7 [KO:K04397] [EC:3.4.22.60]
407883  rhob; rho-related GTP-binding protein RhoB [KO:K07856]
100145522  rhoh; rho-related GTP-binding protein RhoH [KO:K07873]
100144709  akt2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100490038  akt1; RAC-alpha serine/threonine-protein kinase isoform X2 [KO:K04456] [EC:2.7.11.1]
100379899  mlkl; mixed lineage kinase domain-like protein [KO:K08849] [EC:2.7.11.1]
100497621  mixed lineage kinase domain-like protein [KO:K08849] [EC:2.7.11.1]
496541  txn; thioredoxin [KO:K03671]
493523  txn2; thioredoxin, mitochondrial [KO:K03671]
100170420  uncharacterized protein LOC100170420 [KO:K03671]
100170428  uncharacterized protein LOC100170428 [KO:K03671]
100498068  thioredoxin [KO:K03671]
100498224  thioredoxin [KO:K03671]
100497910  thioredoxin [KO:K03671]
116406436  baculoviral IAP repeat-containing protein 1 isoform X1 [KO:K12807]
733844  nlrc4; NLR family CARD domain-containing protein 4 [KO:K12805]
100127742  pycard; PYD and CARD domain containing [KO:K12799]
101732196  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
100491605  casp1; caspase-1-A isoform X1 [KO:K01370] [EC:3.4.22.36]
100496716  interleukin-18 [KO:K05482]
108648098  il18; interleukin-18 [KO:K05482]
Compound
C00338  Lipopolysaccharide
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
  Authors
Bernal-Bayard J, Ramos-Morales F
  Title
Molecular Mechanisms Used by Salmonella to Evade the Immune System.
  Journal
Curr Issues Mol Biol 25:133-168 (2018)
DOI:10.21775/cimb.025.133
Reference
  Authors
Hume PJ, Singh V, Davidson AC, Koronakis V
  Title
Swiss Army Pathogen: The Salmonella Entry Toolkit.
  Journal
Front Cell Infect Microbiol 7:348 (2017)
DOI:10.3389/fcimb.2017.00348
Reference
  Authors
Wemyss MA, Pearson JS
  Title
Host Cell Death Responses to Non-typhoidal Salmonella Infection.
  Journal
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Related
pathway
xtr04010  MAPK signaling pathway
xtr04210  Apoptosis
xtr04217  Necroptosis
xtr04621  NOD-like receptor signaling pathway
KO pathway
ko05132   
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