KEGG   REACTION: R03145
Entry
R03145                      Reaction                               
Name
pyruvate:ubiquinone oxidoreductase
Definition
Pyruvate + Ubiquinone + H2O <=> Acetate + Ubiquinol + CO2
Equation
C00022 + C00399 + C00001 <=> C00033 + C00390 + C00011
Comment
previously called pyruvate:ferricytochrome-b1 oxidoreductase (ec 1.2.2.2)
ubiquinol is re-oxidized by ferricytochrome in respiratory chain
Reaction class
RC00061  C00390_C00399
RC00860  C00022_C00033
Enzyme
1.2.5.1
Pathway
rn00620  Pyruvate metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.5  With a quinone or similar compound as acceptor
    1.2.5.1
     R03145  Pyruvate + Ubiquinone + H2O <=> Acetate + Ubiquinol + CO2
Orthology
K00156  pyruvate dehydrogenase (quinone) [EC:1.2.5.1]
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