U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal change in social behavior

MedGen UID:
1050835
•Concept ID:
CN375717
•
Finding
HPO: HP:5200243

Definition

An alternation in the habits and emotional tendencies of an individual with a change in behavior that is typically noticed by family members or peers. [from HPO]

Professional guidelines

PubMed

Eating Disorders in Primary Care: Diagnosis and Management.
Klein DA, Sylvester JE, Schvey NA
Am Fam Physician 2021 Jan 1;103(1):22-32. PMID: 33382560
Diagnosis and management of behavioral variant frontotemporal dementia.
Pressman PS, Miller BL
Biol Psychiatry 2014 Apr 1;75(7):574-81. Epub 2013 Nov 13 doi: 10.1016/j.biopsych.2013.11.006. PMID: 24315411Free PMC Article
Marfan syndrome-diagnosis and management.
Ammash NM, Sundt TM, Connolly HM
Curr Probl Cardiol 2008 Jan;33(1):7-39. doi: 10.1016/j.cpcardiol.2007.10.001. PMID: 18155514

Recent clinical studies

Etiology

Adolescent stress impairs postpartum social behavior via anterior insula-prelimbic pathway in mice.
Kin K, Francis-Oliveira J, Kano SI, Niwa M
Nat Commun 2023 May 23;14(1):2975. doi: 10.1038/s41467-023-38799-6. PMID: 37221211Free PMC Article
Epigenetics of Autism Spectrum Disorder: Histone Deacetylases.
Tseng CJ, McDougle CJ, Hooker JM, Zürcher NR
Biol Psychiatry 2022 Jun 1;91(11):922-933. Epub 2021 Dec 10 doi: 10.1016/j.biopsych.2021.11.021. PMID: 35120709
Does race or ethnicity play a role in the origin, pathophysiology, and outcomes of preeclampsia? An expert review of the literature.
Johnson JD, Louis JM
Am J Obstet Gynecol 2022 Feb;226(2S):S876-S885. Epub 2020 Jul 24 doi: 10.1016/j.ajog.2020.07.038. PMID: 32717255
The Evidence for Saturated Fat and for Sugar Related to Coronary Heart Disease.
DiNicolantonio JJ, Lucan SC, O'Keefe JH
Prog Cardiovasc Dis 2016 Mar-Apr;58(5):464-72. Epub 2015 Nov 14 doi: 10.1016/j.pcad.2015.11.006. PMID: 26586275Free PMC Article
What is frontotemporal dementia?
Kurz A, Kurz C, Ellis K, Lautenschlager NT
Maturitas 2014 Oct;79(2):216-9. Epub 2014 Jul 3 doi: 10.1016/j.maturitas.2014.07.001. PMID: 25059437

Diagnosis

Eating Disorders in Primary Care: Diagnosis and Management.
Klein DA, Sylvester JE, Schvey NA
Am Fam Physician 2021 Jan 1;103(1):22-32. PMID: 33382560
Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study.
Kang DW, Adams JB, Gregory AC, Borody T, Chittick L, Fasano A, Khoruts A, Geis E, Maldonado J, McDonough-Means S, Pollard EL, Roux S, Sadowsky MJ, Lipson KS, Sullivan MB, Caporaso JG, Krajmalnik-Brown R
Microbiome 2017 Jan 23;5(1):10. doi: 10.1186/s40168-016-0225-7. PMID: 28122648Free PMC Article
The Evidence for Saturated Fat and for Sugar Related to Coronary Heart Disease.
DiNicolantonio JJ, Lucan SC, O'Keefe JH
Prog Cardiovasc Dis 2016 Mar-Apr;58(5):464-72. Epub 2015 Nov 14 doi: 10.1016/j.pcad.2015.11.006. PMID: 26586275Free PMC Article
Metabolic features of the cell danger response.
Naviaux RK
Mitochondrion 2014 May;16:7-17. Epub 2013 Aug 24 doi: 10.1016/j.mito.2013.08.006. PMID: 23981537
Frontotemporal dementia.
Perry DC, Miller BL
Semin Neurol 2013 Sep;33(4):336-41. Epub 2013 Nov 14 doi: 10.1055/s-0033-1359316. PMID: 24234354

Therapy

Psychopathological disorders in Prader-Willi syndrome.
Guinovart M, Coronas R, Caixàs A
Endocrinol Diabetes Nutr (Engl Ed) 2019 Nov;66(9):579-587. Epub 2019 Apr 18 doi: 10.1016/j.endinu.2019.03.004. PMID: 31006652
Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study.
Kang DW, Adams JB, Gregory AC, Borody T, Chittick L, Fasano A, Khoruts A, Geis E, Maldonado J, McDonough-Means S, Pollard EL, Roux S, Sadowsky MJ, Lipson KS, Sullivan MB, Caporaso JG, Krajmalnik-Brown R
Microbiome 2017 Jan 23;5(1):10. doi: 10.1186/s40168-016-0225-7. PMID: 28122648Free PMC Article
The Evidence for Saturated Fat and for Sugar Related to Coronary Heart Disease.
DiNicolantonio JJ, Lucan SC, O'Keefe JH
Prog Cardiovasc Dis 2016 Mar-Apr;58(5):464-72. Epub 2015 Nov 14 doi: 10.1016/j.pcad.2015.11.006. PMID: 26586275Free PMC Article
Sulforaphane treatment of autism spectrum disorder (ASD).
Singh K, Connors SL, Macklin EA, Smith KD, Fahey JW, Talalay P, Zimmerman AW
Proc Natl Acad Sci U S A 2014 Oct 28;111(43):15550-5. Epub 2014 Oct 13 doi: 10.1073/pnas.1416940111. PMID: 25313065Free PMC Article
Cardio-oncology/onco-cardiology.
Hong RA, Iimura T, Sumida KN, Eager RM
Clin Cardiol 2010 Dec;33(12):733-7. doi: 10.1002/clc.20823. PMID: 21184556Free PMC Article

Prognosis

Social Skills and Medical Responsibility Across Development in Youth With Spina Bifida.
Stiles-Shields C, Shirkey KC, Winning AM, Smith ZR, Wartman E, Holmbeck GN
J Pediatr Psychol 2021 Mar 18;46(3):341-350. doi: 10.1093/jpepsy/jsaa113. PMID: 33236095Free PMC Article
Changes in depressed patients' self-statements.
Thompson K, D'iuso D, Schwartzman D, Dobson KS, Drapeau M
Psychother Res 2020 Feb;30(2):170-182. Epub 2018 Nov 13 doi: 10.1080/10503307.2018.1543976. PMID: 30422103
The Evidence for Saturated Fat and for Sugar Related to Coronary Heart Disease.
DiNicolantonio JJ, Lucan SC, O'Keefe JH
Prog Cardiovasc Dis 2016 Mar-Apr;58(5):464-72. Epub 2015 Nov 14 doi: 10.1016/j.pcad.2015.11.006. PMID: 26586275Free PMC Article
Cardio-oncology/onco-cardiology.
Hong RA, Iimura T, Sumida KN, Eager RM
Clin Cardiol 2010 Dec;33(12):733-7. doi: 10.1002/clc.20823. PMID: 21184556Free PMC Article
Frontotemporal dementia.
Honig LS, Bell K, Chin SS
Sci Aging Knowledge Environ 2003 Apr 2;2003(13):DN1. doi: 10.1126/sageke.2003.13.dn1. PMID: 12844524

Clinical prediction guides

Adolescent stress impairs postpartum social behavior via anterior insula-prelimbic pathway in mice.
Kin K, Francis-Oliveira J, Kano SI, Niwa M
Nat Commun 2023 May 23;14(1):2975. doi: 10.1038/s41467-023-38799-6. PMID: 37221211Free PMC Article
Cerebral blood flow self-regulation in depression.
Liu M, He E, Fu X, Gong S, Han Y, Deng F
J Affect Disord 2022 Apr 1;302:324-331. Epub 2022 Jan 13 doi: 10.1016/j.jad.2022.01.057. PMID: 35032508
The Evidence for Saturated Fat and for Sugar Related to Coronary Heart Disease.
DiNicolantonio JJ, Lucan SC, O'Keefe JH
Prog Cardiovasc Dis 2016 Mar-Apr;58(5):464-72. Epub 2015 Nov 14 doi: 10.1016/j.pcad.2015.11.006. PMID: 26586275Free PMC Article
Sulforaphane treatment of autism spectrum disorder (ASD).
Singh K, Connors SL, Macklin EA, Smith KD, Fahey JW, Talalay P, Zimmerman AW
Proc Natl Acad Sci U S A 2014 Oct 28;111(43):15550-5. Epub 2014 Oct 13 doi: 10.1073/pnas.1416940111. PMID: 25313065Free PMC Article
Cardio-oncology/onco-cardiology.
Hong RA, Iimura T, Sumida KN, Eager RM
Clin Cardiol 2010 Dec;33(12):733-7. doi: 10.1002/clc.20823. PMID: 21184556Free PMC Article

Recent systematic reviews

Social isolation and the brain: effects and mechanisms.
Xiong Y, Hong H, Liu C, Zhang YQ
Mol Psychiatry 2023 Jan;28(1):191-201. Epub 2022 Nov 25 doi: 10.1038/s41380-022-01835-w. PMID: 36434053Free PMC Article
Behavior Problems and Social Competence in Fragile X Syndrome: A Systematic Review.
Cregenzán-Royo O, Brun-Gasca C, Fornieles-Deu A
Genes (Basel) 2022 Jan 30;13(2) doi: 10.3390/genes13020280. PMID: 35205326Free PMC Article
Information needs in people with diabetes mellitus: a systematic review.
Biernatzki L, Kuske S, Genz J, Ritschel M, Stephan A, Bächle C, Droste S, Grobosch S, Ernstmann N, Chernyak N, Icks A
Syst Rev 2018 Feb 14;7(1):27. doi: 10.1186/s13643-018-0690-0. PMID: 29444711Free PMC Article
Interventions for psychotic symptoms concomitant with epilepsy.
Farooq S, Sherin A
Cochrane Database Syst Rev 2015 Dec 21;2015(12):CD006118. doi: 10.1002/14651858.CD006118.pub3. PMID: 26690687Free PMC Article
Neurobiological changes after intervention in individuals with anti-social behaviour: a literature review.
Cornet LJ, de Kogel CH, Nijman HL, Raine A, van der Laan PH
Crim Behav Ment Health 2015 Feb;25(1):10-27. Epub 2014 Jun 3 doi: 10.1002/cbm.1915. PMID: 24888269

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...