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Gallbladder carcinoma

MedGen UID:
116001
Concept ID:
C0235782
Neoplastic Process
Synonym: Carcinoma of gallbladder
SNOMED CT: Carcinoma of gallbladder (372140005)
 
Monarch Initiative: MONDO:0003220

Definition

A malignant tumor arising from the epithelium of the gallbladder. It is usually associated with the presence of gallstones. Clinical symptoms are not specific and usually present late in the course. Morphologically, most gallbladder carcinomas are adenocarcinomas; squamous cell carcinomas, adenosquamous carcinomas, signet ring carcinomas, and undifferentiated carcinomas can also occur. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Gallbladder carcinoma
Follow this link to review classifications for Gallbladder carcinoma in Orphanet.

Professional guidelines

PubMed

Giudicelli X, Rode A, Bancel B, Nguyen AT, Mabrut JY
J Visc Surg 2021 Aug;158(4):326-336. Epub 2021 Mar 23 doi: 10.1016/j.jviscsurg.2021.02.004. PMID: 33741306
Ashai N, Prasad P, Rajdev L
Curr Treat Options Oncol 2019 May 29;20(7):58. doi: 10.1007/s11864-019-0655-0. PMID: 31144050
Shukla SK, Singh G, Shahi KS, Bhuvan, Pant P
J Gastrointest Cancer 2018 Mar;49(1):9-15. doi: 10.1007/s12029-017-0036-5. PMID: 29234972

Recent clinical studies

Etiology

Ganeshan D, Kambadakone A, Nikolaidis P, Subbiah V, Subbiah IM, Devine C
Abdom Radiol (NY) 2021 Jun;46(6):2474-2489. Epub 2021 Jan 2 doi: 10.1007/s00261-020-02871-2. PMID: 33386907
Gunasekaran G, Bekki Y, Lourdusamy V, Schwartz M
Hepatology 2021 Jan;73 Suppl 1:128-136. Epub 2020 Nov 26 doi: 10.1002/hep.31325. PMID: 32438491
Gamboa AC, Maithel SK
Ann Surg Oncol 2020 Aug;27(8):2846-2858. Epub 2020 May 30 doi: 10.1245/s10434-020-08654-9. PMID: 32474816
Goetze TO
World J Gastroenterol 2015 Nov 21;21(43):12211-7. doi: 10.3748/wjg.v21.i43.12211. PMID: 26604631Free PMC Article
Gibney EJ
Br J Surg 1990 Apr;77(4):368-72. doi: 10.1002/bjs.1800770405. PMID: 2187558

Diagnosis

Ganeshan D, Kambadakone A, Nikolaidis P, Subbiah V, Subbiah IM, Devine C
Abdom Radiol (NY) 2021 Jun;46(6):2474-2489. Epub 2021 Jan 2 doi: 10.1007/s00261-020-02871-2. PMID: 33386907
Lopes Vendrami C, Magnetta MJ, Mittal PK, Moreno CC, Miller FH
Radiographics 2021 Jan-Feb;41(1):78-95. Epub 2020 Dec 11 doi: 10.1148/rg.2021200087. PMID: 33306452
Gunasekaran G, Bekki Y, Lourdusamy V, Schwartz M
Hepatology 2021 Jan;73 Suppl 1:128-136. Epub 2020 Nov 26 doi: 10.1002/hep.31325. PMID: 32438491
Miyoshi H, Inui K, Katano Y, Tachi Y, Yamamoto S
J Med Ultrason (2001) 2021 Apr;48(2):175-186. Epub 2020 Apr 24 doi: 10.1007/s10396-020-01018-6. PMID: 32333131
Pang L, Zhang Y, Wang Y, Kong J
Braz J Med Biol Res 2018;51(6):e7411. Epub 2018 May 21 doi: 10.1590/1414-431x20187411. PMID: 29791592Free PMC Article

Therapy

Nakachi K, Ikeda M, Konishi M, Nomura S, Katayama H, Kataoka T, Todaka A, Yanagimoto H, Morinaga S, Kobayashi S, Shimada K, Takahashi Y, Nakagohri T, Gotoh K, Kamata K, Shimizu Y, Ueno M, Ishii H, Okusaka T, Furuse J; Hepatobiliary and Pancreatic Oncology Group of the Japan Clinical Oncology Group (JCOG-HBPOG)
Lancet 2023 Jan 21;401(10372):195-203. doi: 10.1016/S0140-6736(22)02038-4. PMID: 36681415
Ilyas FZ, Beane JD, Pawlik TM
Cells 2021 Aug 15;10(8) doi: 10.3390/cells10082096. PMID: 34440865Free PMC Article
Zhang Y, Zuo C, Liu L, Hu Y, Yang B, Qiu S, Li Y, Cao D, Ju Z, Ge J, Wang Q, Wang T, Bai L, Yang Y, Li G, Shao Z, Gao Y, Li Y, Bian R, Miao H, Li L, Li X, Jiang C, Yan S, Wang Z, Wang Z, Cui X, Huang W, Xiang D, Wang C, Li Q, Wu X, Gong W, Liu Y, Shao R, Liu F, Li M, Chen L, Liu Y
J Hepatol 2021 Nov;75(5):1128-1141. Epub 2021 Jun 23 doi: 10.1016/j.jhep.2021.06.023. PMID: 34171432
Gamboa AC, Maithel SK
Ann Surg Oncol 2020 Aug;27(8):2846-2858. Epub 2020 May 30 doi: 10.1245/s10434-020-08654-9. PMID: 32474816
Ben-Josef E, Guthrie KA, El-Khoueiry AB, Corless CL, Zalupski MM, Lowy AM, Thomas CR Jr, Alberts SR, Dawson LA, Micetich KC, Thomas MB, Siegel AB, Blanke CD
J Clin Oncol 2015 Aug 20;33(24):2617-22. Epub 2015 May 11 doi: 10.1200/JCO.2014.60.2219. PMID: 25964250Free PMC Article

Prognosis

Ganeshan D, Kambadakone A, Nikolaidis P, Subbiah V, Subbiah IM, Devine C
Abdom Radiol (NY) 2021 Jun;46(6):2474-2489. Epub 2021 Jan 2 doi: 10.1007/s00261-020-02871-2. PMID: 33386907
Goetze TO
World J Gastroenterol 2015 Nov 21;21(43):12211-7. doi: 10.3748/wjg.v21.i43.12211. PMID: 26604631Free PMC Article
Ben-Josef E, Guthrie KA, El-Khoueiry AB, Corless CL, Zalupski MM, Lowy AM, Thomas CR Jr, Alberts SR, Dawson LA, Micetich KC, Thomas MB, Siegel AB, Blanke CD
J Clin Oncol 2015 Aug 20;33(24):2617-22. Epub 2015 May 11 doi: 10.1200/JCO.2014.60.2219. PMID: 25964250Free PMC Article
Bal MM, Ramadwar M, Deodhar K, Shrikhande S
Pathol Oncol Res 2015 Jul;21(3):509-25. Epub 2015 Jan 25 doi: 10.1007/s12253-014-9886-3. PMID: 25618479
Miller G, Jarnagin WR
Eur J Surg Oncol 2008 Mar;34(3):306-12. Epub 2007 Oct 26 doi: 10.1016/j.ejso.2007.07.206. PMID: 17964753

Clinical prediction guides

Fang J, Fang F, Huang J, Zhang X, Wang H
Cell Mol Biol (Noisy-le-grand) 2022 Aug 31;68(8):64-68. doi: 10.14715/cmb/2022.68.8.11. PMID: 36800835
Imamura H, Adachi T, Tanaka T, Matsushima H, Hara T, Soyama A, Hidaka M, Eguchi S
Anticancer Res 2022 Feb;42(2):903-910. doi: 10.21873/anticanres.15548. PMID: 35093888
Ilyas FZ, Beane JD, Pawlik TM
Cells 2021 Aug 15;10(8) doi: 10.3390/cells10082096. PMID: 34440865Free PMC Article
Zhang Y, Zuo C, Liu L, Hu Y, Yang B, Qiu S, Li Y, Cao D, Ju Z, Ge J, Wang Q, Wang T, Bai L, Yang Y, Li G, Shao Z, Gao Y, Li Y, Bian R, Miao H, Li L, Li X, Jiang C, Yan S, Wang Z, Wang Z, Cui X, Huang W, Xiang D, Wang C, Li Q, Wu X, Gong W, Liu Y, Shao R, Liu F, Li M, Chen L, Liu Y
J Hepatol 2021 Nov;75(5):1128-1141. Epub 2021 Jun 23 doi: 10.1016/j.jhep.2021.06.023. PMID: 34171432
Misra S, Chaturvedi A, Misra NC, Sharma ID
Lancet Oncol 2003 Mar;4(3):167-76. doi: 10.1016/s1470-2045(03)01021-0. PMID: 12623362

Recent systematic reviews

Luvira V, Satitkarnmanee E, Pugkhem A, Kietpeerakool C, Lumbiganon P, Pattanittum P
Cochrane Database Syst Rev 2021 Sep 13;9(9):CD012814. doi: 10.1002/14651858.CD012814.pub2. PMID: 34515993Free PMC Article
Lv TR, Yang C, Regmi P, Ma WJ, Hu HJ, Liu F, Yin CH, Jin YW, Li FY
Asian J Surg 2021 Dec;44(12):1493-1502. Epub 2021 Apr 22 doi: 10.1016/j.asjsur.2021.03.015. PMID: 33895048
Liang YC, Li SG, Wang JY
Surg Laparosc Endosc Percutan Tech 2020 Aug;30(4):381-387. doi: 10.1097/SLE.0000000000000789. PMID: 32287113
Sicklick JK, Fanta PT, Shimabukuro K, Kurzrock R
Cancer Metastasis Rev 2016 Jun;35(2):263-75. doi: 10.1007/s10555-016-9602-8. PMID: 26857926Free PMC Article
Li B, Xu XX, Du Y, Yang HF, Li Y, Zhang Q, Xiao DM, Huang YY, Meng J, Wang WX
Clin Imaging 2013 Mar-Apr;37(2):327-33. Epub 2012 Jun 18 doi: 10.1016/j.clinimag.2012.05.009. PMID: 23465987

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