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Gingival calcification

MedGen UID:
1368801
•Concept ID:
C4476612
•
Finding
Synonym: Gingival calcifications
 
HPO: HP:0025141

Definition

Ectopic deposition of calcium salts found in the gingiva. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGingival calcification

Professional guidelines

PubMed

Four novel mutations of FAM20A in amelogenesis imperfecta type IG and review of literature for its genotype and phenotype spectra.
Nitayavardhana I, Theerapanon T, Srichomthong C, Piwluang S, Wichadakul D, Porntaveetus T, Shotelersuk V
Mol Genet Genomics 2020 Jul;295(4):923-931. Epub 2020 Apr 3 doi: 10.1007/s00438-020-01668-8. PMID: 32246227
Sarcoglycans and integrins in bisphosphonate treatment: immunohistochemical and scanning electron microscopy study.
De Ponte FS, Favaloro A, Siniscalchi EN, Centofanti A, Runci M, Cutroneo G, Catalfamo L
Oncol Rep 2013 Dec;30(6):2639-46. Epub 2013 Oct 1 doi: 10.3892/or.2013.2766. PMID: 24100935
Clinical features, pathogenesis and treatment of juvenile and adult dermatomyositis.
Robinson AB, Reed AM
Nat Rev Rheumatol 2011 Sep 27;7(11):664-75. doi: 10.1038/nrrheum.2011.139. PMID: 21947177

Recent clinical studies

Etiology

Gingival Fibroma: An Emerging Distinct Gingival Lesion with Well-Defined Histopathology.
Bawazir M, Islam MN, Cohen DM, Fitzpatrick S, Bhattacharyya I
Head Neck Pathol 2021 Sep;15(3):917-922. Epub 2021 Mar 8 doi: 10.1007/s12105-021-01315-7. PMID: 33686583Free PMC Article
Use of calcium channel blockers in dermatology: a narrative review.
Lo Y, Lin LY, Tsai TF
Expert Rev Clin Pharmacol 2021 Apr;14(4):481-489. Epub 2021 Feb 26 doi: 10.1080/17512433.2021.1894128. PMID: 33612036
Syndromes with gingival fibromatosis: A systematic review.
Costa CRR, Braz SV, de Toledo IP, Martelli-Júnior H, Mazzeu JF, Guerra ENS, Coletta RD, Acevedo AC
Oral Dis 2021 May;27(4):881-893. Epub 2020 May 25 doi: 10.1111/odi.13369. PMID: 32335995
Preterm infants--odontological aspects.
Rythén M
Swed Dent J Suppl 2012;(224):2p preceding i-vi, 1-106. PMID: 22755470
Papillon-Lefèvre syndrome.
Landow RK, Cheung H, Bauer M
Int J Dermatol 1983 Apr;22(3):177-9. doi: 10.1111/j.1365-4362.1983.tb03359.x. PMID: 6222004

Diagnosis

Enamel-Renal-Syndrome: case report.
Torres LHS, de-Azevedo-Vaz SL, Barroso DRC, Silva DN, Velloso TRG, de Barros LAP
Spec Care Dentist 2018 May;38(3):172-175. Epub 2018 Apr 19 doi: 10.1111/scd.12288. PMID: 29672880
Age-related morphological, histological and functional changes in teeth.
Carvalho TS, Lussi A
J Oral Rehabil 2017 Apr;44(4):291-298. Epub 2017 Jan 28 doi: 10.1111/joor.12474. PMID: 28032898
Preterm infants--odontological aspects.
Rythén M
Swed Dent J Suppl 2012;(224):2p preceding i-vi, 1-106. PMID: 22755470
Dental calculus: recent insights into occurrence, formation, prevention, removal and oral health effects of supragingival and subgingival deposits.
White DJ
Eur J Oral Sci 1997 Oct;105(5 Pt 2):508-22. doi: 10.1111/j.1600-0722.1997.tb00238.x. PMID: 9395117
Papillon-Lefèvre syndrome.
Landow RK, Cheung H, Bauer M
Int J Dermatol 1983 Apr;22(3):177-9. doi: 10.1111/j.1365-4362.1983.tb03359.x. PMID: 6222004

Therapy

Use of calcium channel blockers in dermatology: a narrative review.
Lo Y, Lin LY, Tsai TF
Expert Rev Clin Pharmacol 2021 Apr;14(4):481-489. Epub 2021 Feb 26 doi: 10.1080/17512433.2021.1894128. PMID: 33612036
Clinical features, pathogenesis and treatment of juvenile and adult dermatomyositis.
Robinson AB, Reed AM
Nat Rev Rheumatol 2011 Sep 27;7(11):664-75. doi: 10.1038/nrrheum.2011.139. PMID: 21947177
Sturge-Weber angiomatosis.
Sattur AP, Goyal M
Lancet 2011 Oct 29;378(9802):1580. Epub 2011 Sep 8 doi: 10.1016/S0140-6736(11)60249-3. PMID: 21907403
Pathophysiology, therapy, and oral implications of renal failure in children and adolescents: an update.
Davidovich E, Davidovits M, Eidelman E, Schwarz Z, Bimstein E
Pediatr Dent 2005 Mar-Apr;27(2):98-106. PMID: 15926286
Pathogenesis and prevention of native valve infective endocarditis in elderly dental patients.
Friedlander AH, Marshall CE
Drugs Aging 1994 Apr;4(4):325-30. doi: 10.2165/00002512-199404040-00005. PMID: 8019055

Prognosis

A long-term clinical study on individuals with amelogenesis imperfecta.
Ceyhan D, Kirzioglu Z, Emek T
Niger J Clin Pract 2019 Aug;22(8):1157-1162. doi: 10.4103/njcp.njcp_227_18. PMID: 31417061
Oral cavity health among cystic fibrosis patients: Literature overview.
Herman K, Kowalczyk-Zając M, Pytrus T
Adv Clin Exp Med 2017 Oct;26(7):1147-1153. doi: 10.17219/acem/64054. PMID: 29211365
Clinical features, pathogenesis and treatment of juvenile and adult dermatomyositis.
Robinson AB, Reed AM
Nat Rev Rheumatol 2011 Sep 27;7(11):664-75. doi: 10.1038/nrrheum.2011.139. PMID: 21947177
Sturge-Weber angiomatosis.
Sattur AP, Goyal M
Lancet 2011 Oct 29;378(9802):1580. Epub 2011 Sep 8 doi: 10.1016/S0140-6736(11)60249-3. PMID: 21907403
Endodontic perforations: their prognosis and treatment.
Sinai IH
J Am Dent Assoc 1977 Jul;95(1):90-5. doi: 10.14219/jada.archive.1977.0531. PMID: 267659

Clinical prediction guides

Immunohistochemical Characterization of Gingival Fibromas.
Darling M, Li K, Burnside K, Smith N, Jackson-Boeters L, Hamilton D
Head Neck Pathol 2023 Jun;17(2):355-363. Epub 2022 Dec 6 doi: 10.1007/s12105-022-01493-y. PMID: 36472794Free PMC Article
Clinical and pathologic factors associated with the relapse of fibrous gingival hyperplasia.
Xu K, Zhu Y, Li Y, Huang J, Wan Q, Hao J, Ji Z, Liu Y, Tay FR, Jiao K, Niu L
J Am Dent Assoc 2022 Dec;153(12):1134-1144.e2. Epub 2022 Oct 25 doi: 10.1016/j.adaj.2022.08.014. PMID: 36307356
Gingival epithelial cell-derived microvesicles activate mineralization in gingival fibroblasts.
Kobayashi S, Bi J, Owen G, Larjava N, Koivisto L, Häkkinen L, Larjava H
Sci Rep 2022 Sep 22;12(1):15779. doi: 10.1038/s41598-022-19732-1. PMID: 36138045Free PMC Article
Enamel-Renal-Syndrome: case report.
Torres LHS, de-Azevedo-Vaz SL, Barroso DRC, Silva DN, Velloso TRG, de Barros LAP
Spec Care Dentist 2018 May;38(3):172-175. Epub 2018 Apr 19 doi: 10.1111/scd.12288. PMID: 29672880
Clinical features, pathogenesis and treatment of juvenile and adult dermatomyositis.
Robinson AB, Reed AM
Nat Rev Rheumatol 2011 Sep 27;7(11):664-75. doi: 10.1038/nrrheum.2011.139. PMID: 21947177

Recent systematic reviews

Oral findings in children with congenital cholestatic disease: A systematic review of case reports and case series.
Reynal F, Camoin A, Tardieu C, Fabre A, Blanchet I
Arch Pediatr 2023 Aug;30(6):427-437. Epub 2023 Jun 30 doi: 10.1016/j.arcped.2023.06.003. PMID: 37394364
Syndromes with gingival fibromatosis: A systematic review.
Costa CRR, Braz SV, de Toledo IP, Martelli-Júnior H, Mazzeu JF, Guerra ENS, Coletta RD, Acevedo AC
Oral Dis 2021 May;27(4):881-893. Epub 2020 May 25 doi: 10.1111/odi.13369. PMID: 32335995
Granular cell tumor a study of 42 cases and systemic review of the literature.
Mobarki M, Dumollard JM, Dal Col P, Camy F, Peoc'h M, Karpathiou G
Pathol Res Pract 2020 Apr;216(4):152865. Epub 2020 Feb 12 doi: 10.1016/j.prp.2020.152865. PMID: 32089415

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