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Intralobular interstitial thickening

MedGen UID:
1368837
•Concept ID:
C4476636
•
Finding
HPO: HP:0025176

Definition

A fine reticular pattern on high-resolution computed tomography, with the visible lines separated by a few millimeters. Regions of the lung with intralobular interstitial thickening characteristically show a fine lacelike or netlike appearance. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIntralobular interstitial thickening

Recent clinical studies

Etiology

Peripheral interstitial lung abnormalities on LDCT in an asymptomatic, nonsmoking Chinese urban cohort.
Gao Z, Li X, Li Y, Zhang C, Li Y, Sun M, Wu Y, Li S, Zhang Y
Medicine (Baltimore) 2023 Apr 21;102(16):e33630. doi: 10.1097/MD.0000000000033630. PMID: 37083763Free PMC Article
Comparison of initial high-resolution computed tomography (HRCT) features of coronavirus disease 2019 (COVID-19) pneumonia and other viral pneumonias.
Huang Y, Jiang Y, Li Z, Han D, Wu L, Ma J, Wang P, Xie Y, Li Z, Li X, Hong M, Zhou J, Duan C, Yang Y, Zhao W, Yuan F, Wang K, Yi W, He B
Ann Palliat Med 2021 Jan;10(1):560-571. doi: 10.21037/apm-20-2479. PMID: 33545786
Imaging features of the initial chest thin-section CT scans from 110 patients after admission with suspected or confirmed diagnosis of COVID-19.
Long CJ, Fang P, Song TJ, Zhang JC, Yang Q
BMC Med Imaging 2020 Jun 15;20(1):64. doi: 10.1186/s12880-020-00464-5. PMID: 32539692Free PMC Article
High-resolution CT findings of re-expansion pulmonary edema.
Baik JH, Ahn MI, Park YH, Park SH
Korean J Radiol 2010 Mar-Apr;11(2):164-8. Epub 2010 Feb 22 doi: 10.3348/kjr.2010.11.2.164. PMID: 20191063Free PMC Article
Smoking-related interstitial lung diseases: radiologic-pathologic correlation.
Hidalgo A, Franquet T, Giménez A, Bordes R, Pineda R, Madrid M
Eur Radiol 2006 Nov;16(11):2463-70. Epub 2006 Jul 25 doi: 10.1007/s00330-006-0340-0. PMID: 16865368

Diagnosis

Imaging features of the initial chest thin-section CT scans from 110 patients after admission with suspected or confirmed diagnosis of COVID-19.
Long CJ, Fang P, Song TJ, Zhang JC, Yang Q
BMC Med Imaging 2020 Jun 15;20(1):64. doi: 10.1186/s12880-020-00464-5. PMID: 32539692Free PMC Article
Smoking-related interstitial lung diseases: radiologic-pathologic correlation.
Hidalgo A, Franquet T, Giménez A, Bordes R, Pineda R, Madrid M
Eur Radiol 2006 Nov;16(11):2463-70. Epub 2006 Jul 25 doi: 10.1007/s00330-006-0340-0. PMID: 16865368
Drug-induced pneumonitis: thin-section CT findings in 60 patients.
Akira M, Ishikawa H, Yamamoto S
Radiology 2002 Sep;224(3):852-60. doi: 10.1148/radiol.2243011236. PMID: 12202725
X-linked dyskeratosis congenita: restrictive pulmonary disease and a novel mutation.
Safa WF, Lestringant GG, Frossard PM
Thorax 2001 Nov;56(11):891-4. doi: 10.1136/thorax.56.11.891. PMID: 11641517Free PMC Article
Serial high resolution CT findings in nonspecific interstitial pneumonia/fibrosis.
Nishiyama O, Kondoh Y, Taniguchi H, Yamaki K, Suzuki R, Yokoi T, Takagi K
J Comput Assist Tomogr 2000 Jan-Feb;24(1):41-6. doi: 10.1097/00004728-200001000-00008. PMID: 10667656

Therapy

CT Findings in People Who Were Environmentally Exposed to Asbestos in Korea.
Lee EK, Kim JS, Kim Y, Park JS
J Korean Med Sci 2015 Dec;30(12):1896-901. Epub 2015 Nov 30 doi: 10.3346/jkms.2015.30.12.1896. PMID: 26713068Free PMC Article
Smoking-related interstitial lung diseases: radiologic-pathologic correlation.
Hidalgo A, Franquet T, Giménez A, Bordes R, Pineda R, Madrid M
Eur Radiol 2006 Nov;16(11):2463-70. Epub 2006 Jul 25 doi: 10.1007/s00330-006-0340-0. PMID: 16865368
Drug-induced pneumonitis: thin-section CT findings in 60 patients.
Akira M, Ishikawa H, Yamamoto S
Radiology 2002 Sep;224(3):852-60. doi: 10.1148/radiol.2243011236. PMID: 12202725

Prognosis

X-linked dyskeratosis congenita: restrictive pulmonary disease and a novel mutation.
Safa WF, Lestringant GG, Frossard PM
Thorax 2001 Nov;56(11):891-4. doi: 10.1136/thorax.56.11.891. PMID: 11641517Free PMC Article

Clinical prediction guides

Peripheral interstitial lung abnormalities on LDCT in an asymptomatic, nonsmoking Chinese urban cohort.
Gao Z, Li X, Li Y, Zhang C, Li Y, Sun M, Wu Y, Li S, Zhang Y
Medicine (Baltimore) 2023 Apr 21;102(16):e33630. doi: 10.1097/MD.0000000000033630. PMID: 37083763Free PMC Article
Comparison of initial high-resolution computed tomography (HRCT) features of coronavirus disease 2019 (COVID-19) pneumonia and other viral pneumonias.
Huang Y, Jiang Y, Li Z, Han D, Wu L, Ma J, Wang P, Xie Y, Li Z, Li X, Hong M, Zhou J, Duan C, Yang Y, Zhao W, Yuan F, Wang K, Yi W, He B
Ann Palliat Med 2021 Jan;10(1):560-571. doi: 10.21037/apm-20-2479. PMID: 33545786
CT Findings in People Who Were Environmentally Exposed to Asbestos in Korea.
Lee EK, Kim JS, Kim Y, Park JS
J Korean Med Sci 2015 Dec;30(12):1896-901. Epub 2015 Nov 30 doi: 10.3346/jkms.2015.30.12.1896. PMID: 26713068Free PMC Article
High-resolution CT findings of re-expansion pulmonary edema.
Baik JH, Ahn MI, Park YH, Park SH
Korean J Radiol 2010 Mar-Apr;11(2):164-8. Epub 2010 Feb 22 doi: 10.3348/kjr.2010.11.2.164. PMID: 20191063Free PMC Article
Smoking-related interstitial lung diseases: radiologic-pathologic correlation.
Hidalgo A, Franquet T, Giménez A, Bordes R, Pineda R, Madrid M
Eur Radiol 2006 Nov;16(11):2463-70. Epub 2006 Jul 25 doi: 10.1007/s00330-006-0340-0. PMID: 16865368

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