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Depressed mood

MedGen UID:
137999
•Concept ID:
C0344315
•
Mental or Behavioral Dysfunction
Synonyms: Decreased Mood; Depressed; Depressed Mood; Low Mood
SNOMED CT: Depressed (35489007); Depressed mood (366979004)

Definition

An emotional state characterized by feelings of sadness, emptiness, and/or tearfulness. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDepressed mood

Professional guidelines

PubMed

Clinical management of cannabis withdrawal.
Connor JP, Stjepanović D, Budney AJ, Le Foll B, Hall WD
Addiction 2022 Jul;117(7):2075-2095. Epub 2022 Jan 10 doi: 10.1111/add.15743. PMID: 34791767Free PMC Article
Chronic Pain Management in the Elderly.
Schwan J, Sclafani J, Tawfik VL
Anesthesiol Clin 2019 Sep;37(3):547-560. Epub 2019 Jun 18 doi: 10.1016/j.anclin.2019.04.012. PMID: 31337484Free PMC Article
Depression in the Primary Care Setting.
Park LT, Zarate CA Jr
N Engl J Med 2019 Feb 7;380(6):559-568. doi: 10.1056/NEJMcp1712493. PMID: 30726688Free PMC Article

Recent clinical studies

Etiology

Intersecting identities and adolescent depression: Patterns of depressed mood and anhedonia in the past decade.
Cohen JR, Thakur H
J Affect Disord 2022 Dec 15;319:518-525. Epub 2022 Sep 23 doi: 10.1016/j.jad.2022.09.088. PMID: 36162694
Ethnic discrimination and depressed mood: The role of autonomic regulation.
Hagen JM, Sutterland AL, Collard D, de Jonge CDE, van Zuiden M, Zantvoord JB, Tan HL, van Valkengoed IGM, van den Born BJH, Zwinderman AH, de Haan L, Lok A
J Psychiatr Res 2021 Dec;144:110-117. Epub 2021 Sep 23 doi: 10.1016/j.jpsychires.2021.09.048. PMID: 34619489
Depressed Mood Prior to Death.
Schlagbaum P, Ruch DA, Tissue JL, Sheftall AH, Bridge JA
Crisis 2020 Nov;41(6):445-452. Epub 2020 Apr 2 doi: 10.1027/0227-5910/a000660. PMID: 32238075
Active and Passive Social Media Use and Symptoms of Anxiety and Depressed Mood Among Icelandic Adolescents.
Thorisdottir IE, Sigurvinsdottir R, Asgeirsdottir BB, Allegrante JP, Sigfusdottir ID
Cyberpsychol Behav Soc Netw 2019 Aug;22(8):535-542. Epub 2019 Jul 30 doi: 10.1089/cyber.2019.0079. PMID: 31361508
Depressed mood and flow-mediated dilation: a systematic review and meta-analysis.
Cooper DC, Tomfohr LM, Milic MS, Natarajan L, Bardwell WA, Ziegler MG, Dimsdale JE
Psychosom Med 2011 Jun;73(5):360-9. Epub 2011 Jun 2 doi: 10.1097/PSY.0b013e31821db79a. PMID: 21636660Free PMC Article

Diagnosis

Major depressive disorder: Biomarkers and biosensors.
Dadkhah M, Jafarzadehgharehziaaddin M, Molaei S, Akbari M, Gholizadeh N, Fathi F
Clin Chim Acta 2023 Jul 1;547:117437. Epub 2023 Jun 12 doi: 10.1016/j.cca.2023.117437. PMID: 37315724
Ethnic discrimination and depressed mood: The role of autonomic regulation.
Hagen JM, Sutterland AL, Collard D, de Jonge CDE, van Zuiden M, Zantvoord JB, Tan HL, van Valkengoed IGM, van den Born BJH, Zwinderman AH, de Haan L, Lok A
J Psychiatr Res 2021 Dec;144:110-117. Epub 2021 Sep 23 doi: 10.1016/j.jpsychires.2021.09.048. PMID: 34619489
The assessment of musculoskeletal pain.
Hawker GA
Clin Exp Rheumatol 2017 Sep-Oct;35 Suppl 107(5):8-12. Epub 2017 Sep 28 PMID: 28967361
Kleine-Levin Syndrome.
Arnulf I
Sleep Med Clin 2015 Jun;10(2):151-61. doi: 10.1016/j.jsmc.2015.02.001. PMID: 26055863
Depression.
Rakel RE
Prim Care 1999 Jun;26(2):211-24. doi: 10.1016/s0095-4543(08)70003-4. PMID: 10318745

Therapy

Acupuncture for comorbid depression and insomnia in perimenopause: A feasibility patient-assessor-blinded, randomized, and sham-controlled clinical trial.
Zhao FY, Zheng Z, Fu QQ, Conduit R, Xu H, Wang HR, Huang YL, Jiang T, Zhang WJ, Kennedy GA
Front Public Health 2023;11:1120567. Epub 2023 Feb 6 doi: 10.3389/fpubh.2023.1120567. PMID: 36815166Free PMC Article
Efficacy and Safety of Nutraceutical on Menopausal Symptoms in Post-Menopausal Women: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Rattanatantikul T, Maiprasert M, Sugkraroek P, Bumrungpert A
J Diet Suppl 2022;19(2):168-183. Epub 2020 Dec 17 doi: 10.1080/19390211.2020.1853648. PMID: 33331798
The Effects of Grounding (Earthing) on Bodyworkers' Pain and Overall Quality of Life: A Randomized Controlled Trial.
Chevalier G, Patel S, Weiss L, Chopra D, Mills PJ
Explore (NY) 2019 May-Jun;15(3):181-190. Epub 2018 Oct 11 doi: 10.1016/j.explore.2018.10.001. PMID: 30448083
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial.
Griffiths RR, Johnson MW, Carducci MA, Umbricht A, Richards WA, Richards BD, Cosimano MP, Klinedinst MA
J Psychopharmacol 2016 Dec;30(12):1181-1197. doi: 10.1177/0269881116675513. PMID: 27909165Free PMC Article
Effects of a palliative care intervention on clinical outcomes in patients with advanced cancer: the Project ENABLE II randomized controlled trial.
Bakitas M, Lyons KD, Hegel MT, Balan S, Brokaw FC, Seville J, Hull JG, Li Z, Tosteson TD, Byock IR, Ahles TA
JAMA 2009 Aug 19;302(7):741-9. doi: 10.1001/jama.2009.1198. PMID: 19690306Free PMC Article

Prognosis

The Age-Dependent Association Between Vascular Risk Factors and Depressed Mood.
Blöchl M, Schaare HL, Kunzmann U, Nestler S
J Gerontol B Psychol Sci Soc Sci 2022 Feb 3;77(2):284-294. doi: 10.1093/geronb/gbab063. PMID: 34080633Free PMC Article
Reducing stress, anxiety and depression in undergraduate nursing students: Systematic review.
Aloufi MA, Jarden RJ, Gerdtz MF, Kapp S
Nurse Educ Today 2021 Jul;102:104877. Epub 2021 Mar 18 doi: 10.1016/j.nedt.2021.104877. PMID: 33905898
Depressed Mood Prior to Death.
Schlagbaum P, Ruch DA, Tissue JL, Sheftall AH, Bridge JA
Crisis 2020 Nov;41(6):445-452. Epub 2020 Apr 2 doi: 10.1027/0227-5910/a000660. PMID: 32238075
Identifying risk factors for first-episode neck pain: A systematic review.
Kim R, Wiest C, Clark K, Cook C, Horn M
Musculoskelet Sci Pract 2018 Feb;33:77-83. Epub 2017 Nov 22 doi: 10.1016/j.msksp.2017.11.007. PMID: 29197234
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial.
Griffiths RR, Johnson MW, Carducci MA, Umbricht A, Richards WA, Richards BD, Cosimano MP, Klinedinst MA
J Psychopharmacol 2016 Dec;30(12):1181-1197. doi: 10.1177/0269881116675513. PMID: 27909165Free PMC Article

Clinical prediction guides

Depressed Mood Prediction of Elderly People with a Wearable Band.
Choi J, Lee S, Kim S, Kim D, Kim H
Sensors (Basel) 2022 May 31;22(11) doi: 10.3390/s22114174. PMID: 35684797Free PMC Article
Depressed mood and repetitive negative thinking in Delayed Sleep-Wake Phase Disorder: Treatment effects and a comparison with good sleepers.
Richardson C, Gradisar M
J Sleep Res 2022 Feb;31(1):e13452. Epub 2021 Aug 4 doi: 10.1111/jsr.13452. PMID: 34350657
The Age-Dependent Association Between Vascular Risk Factors and Depressed Mood.
Blöchl M, Schaare HL, Kunzmann U, Nestler S
J Gerontol B Psychol Sci Soc Sci 2022 Feb 3;77(2):284-294. doi: 10.1093/geronb/gbab063. PMID: 34080633Free PMC Article
Depressed mood, associated factors, and understanding of delirium among caregivers of patients with delirium.
Kim SY, Jhon M, Kang HJ, Lee JY, Kim SW, Kim JM, Shin IS
Int J Psychiatry Med 2022 Mar;57(2):153-164. Epub 2021 Mar 2 doi: 10.1177/0091217421989146. PMID: 33653170
Association between depressed mood and sexual function among mid-aged Paraguayan women.
Sánchez-Zarza SC, Mezones-Holguín E, López-Baena MT, Soto-Becerra P, Pérez-López FR, Gavilanes AWD, Chedraui P
Climacteric 2020 Dec;23(6):566-573. Epub 2020 Apr 8 doi: 10.1080/13697137.2020.1742684. PMID: 32266841

Recent systematic reviews

Probiotics for the treatment of depression and its comorbidities: A systemic review.
Gao J, Zhao L, Cheng Y, Lei W, Wang Y, Liu X, Zheng N, Shao L, Chen X, Sun Y, Ling Z, Xu W
Front Cell Infect Microbiol 2023;13:1167116. Epub 2023 Apr 17 doi: 10.3389/fcimb.2023.1167116. PMID: 37139495Free PMC Article
The global prevalence of major depressive disorder (MDD) among the elderly: A systematic review and meta-analysis.
Abdoli N, Salari N, Darvishi N, Jafarpour S, Solaymani M, Mohammadi M, Shohaimi S
Neurosci Biobehav Rev 2022 Jan;132:1067-1073. Epub 2021 Nov 4 doi: 10.1016/j.neubiorev.2021.10.041. PMID: 34742925
Reducing stress, anxiety and depression in undergraduate nursing students: Systematic review.
Aloufi MA, Jarden RJ, Gerdtz MF, Kapp S
Nurse Educ Today 2021 Jul;102:104877. Epub 2021 Mar 18 doi: 10.1016/j.nedt.2021.104877. PMID: 33905898
Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic.
Rogers JP, Chesney E, Oliver D, Pollak TA, McGuire P, Fusar-Poli P, Zandi MS, Lewis G, David AS
Lancet Psychiatry 2020 Jul;7(7):611-627. Epub 2020 May 18 doi: 10.1016/S2215-0366(20)30203-0. PMID: 32437679Free PMC Article
Identifying risk factors for first-episode neck pain: A systematic review.
Kim R, Wiest C, Clark K, Cook C, Horn M
Musculoskelet Sci Pract 2018 Feb;33:77-83. Epub 2017 Nov 22 doi: 10.1016/j.msksp.2017.11.007. PMID: 29197234

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