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Peritoneal fibrosis

MedGen UID:
141740
•Concept ID:
C0521607
•
Disease or Syndrome
Synonyms: Fibroses, Peritoneal; Fibrosing Syndrome, Peritoneal; Fibrosing Syndromes, Peritoneal; Fibrosis, Peritoneal; Peritoneal Fibroses; Peritoneal Fibrosing Syndrome; Peritoneal Fibrosing Syndromes; Peritoneal Fibrosis; Syndrome, Peritoneal Fibrosing; Syndromes, Peritoneal Fibrosing
SNOMED CT: Peritoneal fibrosis (95550001); Fibrosis of peritoneal serous membrane (95550001); Fibrosis of peritoneum (95550001)

Definition

Disorder characterized by a wide range of structural changes in PERITONEUM, resulting from fibrogenic or inflammatory processes. Peritoneal fibrosis is a common complication in patients receiving PERITONEAL DIALYSIS and contributes to its gradual decrease in efficiency. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPeritoneal fibrosis

Professional guidelines

PubMed

CXCR4-Receptor-Targeted Liposomes for the Treatment of Peritoneal Fibrosis.
Asifullah K, Zhou Z, He W, Gao K, Khan MW, Faisal R, Muhammad H, Sun M
Mol Pharm 2019 Jun 3;16(6):2728-2741. Epub 2019 May 23 doi: 10.1021/acs.molpharmaceut.9b00266. PMID: 31070930
New insights into the pathogenesis and treatment of peritoneal fibrosis: a potential role of Wnt/β-catenin induced epithelial to mesenchymal transition and stem cells for therapy.
Zhang F, Liu H, Liu F, Peng Y, Chen M, Liu Y, Chen G
Med Hypotheses 2013 Jul;81(1):97-100. Epub 2013 Apr 25 doi: 10.1016/j.mehy.2013.03.036. PMID: 23623424
Pathogenesis and treatment of peritoneal membrane failure.
Saxena R
Pediatr Nephrol 2008 May;23(5):695-703. Epub 2007 Sep 21 doi: 10.1007/s00467-007-0580-5. PMID: 17891546

Recent clinical studies

Etiology

Advances in stem cell therapy for peritoneal fibrosis: from mechanisms to therapeutics.
Huang W, Xia D, Bi W, Lai X, Yu B, Chen W
Stem Cell Res Ther 2023 Oct 10;14(1):293. doi: 10.1186/s13287-023-03520-3. PMID: 37817212Free PMC Article
A Clinically Relevant Murine Model of Peritoneal Fibrosis by Dialysate and Catheters.
Chen YT, Lin SL
J Vis Exp 2022 Jun 10;(184) doi: 10.3791/63901. PMID: 35758703
Encapsulating peritoneal sclerosis.
Danford CJ, Lin SC, Smith MP, Wolf JL
World J Gastroenterol 2018 Jul 28;24(28):3101-3111. doi: 10.3748/wjg.v24.i28.3101. PMID: 30065556Free PMC Article
Surgical Management of Complications with Peritoneal Dialysis.
Ratajczak A, Lange-Ratajczak M, Bobkiewicz A, Studniarek A
Semin Dial 2017 Jan;30(1):63-68. Epub 2016 Sep 6 doi: 10.1111/sdi.12538. PMID: 27596540
Gardner's syndrome.
Watne AL, Core SK, Carrier JM
Surg Gynecol Obstet 1975 Jul;141(1):53-6. PMID: 1154213

Diagnosis

Noncoding RNAs in peritoneal fibrosis: Background, Mechanism, and Therapeutic Approach.
Guo Y, Wang L, Gou R, Tang L, Liu P
Biomed Pharmacother 2020 Sep;129:110385. Epub 2020 Jul 2 doi: 10.1016/j.biopha.2020.110385. PMID: 32768932
Encapsulating Peritoneal Sclerosis: The Abdominal Cocoon.
Singhal M, Krishna S, Lal A, Narayanasamy S, Bal A, Yadav TD, Kochhar R, Sinha SK, Khandelwal N, Sheikh AM
Radiographics 2019 Jan-Feb;39(1):62-77. Epub 2018 Dec 7 doi: 10.1148/rg.2019180108. PMID: 30526331
Encapsulating peritoneal sclerosis.
Danford CJ, Lin SC, Smith MP, Wolf JL
World J Gastroenterol 2018 Jul 28;24(28):3101-3111. doi: 10.3748/wjg.v24.i28.3101. PMID: 30065556Free PMC Article
Encapsulating Peritoneal Sclerosis.
Alston H, Fan S, Nakayama M
Semin Nephrol 2017 Jan;37(1):93-102. doi: 10.1016/j.semnephrol.2016.10.010. PMID: 28153198
Preventing peritoneal membrane fibrosis in peritoneal dialysis patients.
Zhou Q, Bajo MA, Del Peso G, Yu X, Selgas R
Kidney Int 2016 Sep;90(3):515-24. Epub 2016 Jun 7 doi: 10.1016/j.kint.2016.03.040. PMID: 27282936

Therapy

Fibrosis of Peritoneal Membrane as Target of New Therapies in Peritoneal Dialysis.
Masola V, Bonomini M, Borrelli S, Di Liberato L, Vecchi L, Onisto M, Gambaro G, Palumbo R, Arduini A
Int J Mol Sci 2022 Apr 27;23(9) doi: 10.3390/ijms23094831. PMID: 35563220Free PMC Article
Inhibition of hyperglycolysis in mesothelial cells prevents peritoneal fibrosis.
Si M, Wang Q, Li Y, Lin H, Luo D, Zhao W, Dou X, Liu J, Zhang H, Huang Y, Lou T, Hu Z, Peng H
Sci Transl Med 2019 Jun 5;11(495) doi: 10.1126/scitranslmed.aav5341. PMID: 31167927
CX3CL1-CX3CR1 interaction mediates macrophage-mesothelial cross talk and promotes peritoneal fibrosis.
Helmke A, Nordlohne J, Balzer MS, Dong L, Rong S, Hiss M, Shushakova N, Haller H, von Vietinghoff S
Kidney Int 2019 Jun;95(6):1405-1417. Epub 2019 Mar 5 doi: 10.1016/j.kint.2018.12.030. PMID: 30948201
Encapsulating peritoneal sclerosis.
Danford CJ, Lin SC, Smith MP, Wolf JL
World J Gastroenterol 2018 Jul 28;24(28):3101-3111. doi: 10.3748/wjg.v24.i28.3101. PMID: 30065556Free PMC Article
Peritoneal Membrane Preservation.
Bajo MA, Del Peso G, Teitelbaum I
Semin Nephrol 2017 Jan;37(1):77-92. doi: 10.1016/j.semnephrol.2016.10.009. PMID: 28153197

Prognosis

Tamoxifen exerts anti-peritoneal fibrosis effects by inhibiting H19-activated VEGFA transcription.
Zhao T, Sun Z, Lai X, Lu H, Liu L, Li S, Yuan JH, Guo Z
J Transl Med 2023 Sep 11;21(1):614. doi: 10.1186/s12967-023-04470-3. PMID: 37697303Free PMC Article
Encapsulating Peritoneal Sclerosis: The Abdominal Cocoon.
Singhal M, Krishna S, Lal A, Narayanasamy S, Bal A, Yadav TD, Kochhar R, Sinha SK, Khandelwal N, Sheikh AM
Radiographics 2019 Jan-Feb;39(1):62-77. Epub 2018 Dec 7 doi: 10.1148/rg.2019180108. PMID: 30526331
Current Status of Peritoneal Dialysis in Japan.
Ito Y, Tawada M, Tine S, Mizuno M, Suzuki Y, Katsuno T
Contrib Nephrol 2018;196:123-128. Epub 2018 Jul 24 doi: 10.1159/000485711. PMID: 30041216
The truth on current peritoneal dialysis: state of the art.
Krediet RT, Abrahams AC, de Fijter CWH, Betjes MGH, Boer WH, van Jaarsveld BC, Konings CJAM, Dekker FW
Neth J Med 2017 Jun;75(5):179-189. PMID: 28653946
Surgical Management of Complications with Peritoneal Dialysis.
Ratajczak A, Lange-Ratajczak M, Bobkiewicz A, Studniarek A
Semin Dial 2017 Jan;30(1):63-68. Epub 2016 Sep 6 doi: 10.1111/sdi.12538. PMID: 27596540

Clinical prediction guides

Tamoxifen exerts anti-peritoneal fibrosis effects by inhibiting H19-activated VEGFA transcription.
Zhao T, Sun Z, Lai X, Lu H, Liu L, Li S, Yuan JH, Guo Z
J Transl Med 2023 Sep 11;21(1):614. doi: 10.1186/s12967-023-04470-3. PMID: 37697303Free PMC Article
SGK1, a Critical Regulator of Immune Modulation and Fibrosis and a Potential Therapeutic Target in Chronic Graft-Versus-Host Disease.
Lu RQ, Zhang YY, Zhao HQ, Guo RQ, Jiang ZX, Guo R
Front Immunol 2022;13:822303. Epub 2022 Feb 10 doi: 10.3389/fimmu.2022.822303. PMID: 35222400Free PMC Article
Peritoneal Expression of SGLT-2, GLUT1, and GLUT3 in Peritoneal Dialysis Patients.
Schricker S, Oberacker T, Fritz P, Ketteler M, Alscher MD, Schanz M
Kidney Blood Press Res 2022;47(2):125-134. Epub 2021 Nov 15 doi: 10.1159/000520894. PMID: 34781282
Current Status of Peritoneal Dialysis in Japan.
Ito Y, Tawada M, Tine S, Mizuno M, Suzuki Y, Katsuno T
Contrib Nephrol 2018;196:123-128. Epub 2018 Jul 24 doi: 10.1159/000485711. PMID: 30041216
A review of rodent models of peritoneal dialysis and its complications.
Wang J, Liu S, Li H, Sun J, Zhang S, Xu X, Liu Y, Wang Y, Miao L
Int Urol Nephrol 2015 Jan;47(1):209-15. Epub 2014 Nov 26 doi: 10.1007/s11255-014-0829-4. PMID: 25425436

Recent systematic reviews

Abdominal cocoon syndrome: Rare cause of intestinal obstruction-Case report and systematic review of literature.
Chorti A, Panidis S, Konstantinidis D, Cheva A, Papavramidis T, Michalopoulos A, Paramythiotis D
Medicine (Baltimore) 2022 Jul 8;101(27):e29837. doi: 10.1097/MD.0000000000029837. PMID: 35801789Free PMC Article
Mechanisms of Peritoneal Fibrosis: Focus on Immune Cells-Peritoneal Stroma Interactions.
Terri M, Trionfetti F, Montaldo C, Cordani M, Tripodi M, Lopez-Cabrera M, Strippoli R
Front Immunol 2021;12:607204. Epub 2021 Mar 29 doi: 10.3389/fimmu.2021.607204. PMID: 33854496Free PMC Article
Luteinized thecoma (thecomatosis) with sclerosing peritonitis: a systematic review of the literature of the last 25 years.
Muratori L, Trevisi E, Delcuratolo MD, Sperone P, Di Maio M
Expert Rev Anticancer Ther 2021 Jan;21(1):23-32. Epub 2020 Oct 22 doi: 10.1080/14737140.2021.1837629. PMID: 33053314
MicroRNAs in peritoneal fibrosis: a systematic review.
Yanai K, Ishii H, Aomatsu A, Ishibashi K, Morishita Y
Discov Med 2018 Dec;26(145):271-280. PMID: 30695676
A systematic review of preclinical studies on therapeutic potential of stem cells or stem cells products in peritoneal fibrosis.
Alatab S, Najafi I, Atlasi R, Pourmand G, Tabatabaei-Malazy O, Ahmadbeigi N
Minerva Urol Nefrol 2018 Apr;70(2):162-178. Epub 2017 Mar 31 doi: 10.23736/S0393-2249.17.02882-X. PMID: 28362076

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