U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Growth Plate Closed

MedGen UID:
1621891
•Concept ID:
C4528294
•
Finding

Definition

A finding indicating that the epiphyseal plate is fully calcified. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrowth Plate Closed

Professional guidelines

PubMed

Nonoperative treatment for osteochondritis dissecans of the capitellum.
Mihara K, Tsutsui H, Nishinaka N, Yamaguchi K
Am J Sports Med 2009 Feb;37(2):298-304. Epub 2008 Dec 4 doi: 10.1177/0363546508324970. PMID: 19059891
Classification, treatment, and outcome of osteochondritis dissecans of the humeral capitellum. Surgical technique.
Takahara M, Mura N, Sasaki J, Harada M, Ogino T
J Bone Joint Surg Am 2008 Mar;90 Suppl 2 Pt 1:47-62. doi: 10.2106/JBJS.G.01135. PMID: 18310686

Recent clinical studies

Etiology

Nutritional rickets & osteomalacia: A practical approach to management.
Uday S, Högler W
Indian J Med Res 2020 Oct;152(4):356-367. doi: 10.4103/ijmr.IJMR_1961_19. PMID: 33380700Free PMC Article
Shoulder and Elbow Injuries in the Adolescent Throwing Athlete.
DeFroda S, McGlone P, Levins J, O'Donnell R, Cruz AI, Kriz PK
R I Med J (2013) 2020 Sep 1;103(7):21-29. PMID: 32872686
Stem and progenitor cells in skeletal development.
Ono N, Balani DH, Kronenberg HM
Curr Top Dev Biol 2019;133:1-24. Epub 2019 Feb 10 doi: 10.1016/bs.ctdb.2019.01.006. PMID: 30902249Free PMC Article
Peritonsillar abscess: clinical aspects of microbiology, risk factors, and the association with parapharyngeal abscess.
Klug TE
Dan Med J 2017 Mar;64(3) PMID: 28260599
Ollier disease.
Silve C, Jüppner H
Orphanet J Rare Dis 2006 Sep 22;1:37. doi: 10.1186/1750-1172-1-37. PMID: 16995932Free PMC Article

Diagnosis

Nutritional rickets & osteomalacia: A practical approach to management.
Uday S, Högler W
Indian J Med Res 2020 Oct;152(4):356-367. doi: 10.4103/ijmr.IJMR_1961_19. PMID: 33380700Free PMC Article
Peritonsillar abscess: clinical aspects of microbiology, risk factors, and the association with parapharyngeal abscess.
Klug TE
Dan Med J 2017 Mar;64(3) PMID: 28260599
Closing the growth plate: a review of indications and surgical options.
Ruzbarsky JJ, Goodbody C, Dodwell E
Curr Opin Pediatr 2017 Feb;29(1):80-86. doi: 10.1097/MOP.0000000000000438. PMID: 27845969
Ollier disease.
Silve C, Jüppner H
Orphanet J Rare Dis 2006 Sep 22;1:37. doi: 10.1186/1750-1172-1-37. PMID: 16995932Free PMC Article
Hypochondrogenesis.
Maroteaux P, Stanescu V, Stanescu R
Eur J Pediatr 1983 Oct;141(1):14-22. doi: 10.1007/BF00445662. PMID: 6641761

Therapy

Efficacy and Safety of "Sleeper Plate" in Temporary Hemiepiphysiodesis and the Observation of "Tethering".
Gerges M, Messner J, Lim B, Chhina H, Cooper A
J Pediatr Orthop 2022 Aug 1;42(7):e762-e766. Epub 2022 May 20 doi: 10.1097/BPO.0000000000002184. PMID: 35605208
Management of Distal Radius Fractures in Adolescent Patients.
Greig D, Silva M
J Pediatr Orthop 2021 Jul 1;41(Suppl 1):S1-S5. doi: 10.1097/BPO.0000000000001778. PMID: 34096530Free PMC Article
Peritonsillar abscess: clinical aspects of microbiology, risk factors, and the association with parapharyngeal abscess.
Klug TE
Dan Med J 2017 Mar;64(3) PMID: 28260599
Clinical practice: the hip from birth to adolescence.
Fabry G
Eur J Pediatr 2010 Feb;169(2):143-8. doi: 10.1007/s00431-009-1025-x. PMID: 19727813
Matrix vesicles and calcification.
Anderson HC
Curr Rheumatol Rep 2003 Jun;5(3):222-6. doi: 10.1007/s11926-003-0071-z. PMID: 12744815

Prognosis

Combination of RUNX1 inhibitor and gemcitabine mitigates chemo-resistance in pancreatic ductal adenocarcinoma by modulating BiP/PERK/eIF2α-axis-mediated endoplasmic reticulum stress.
She C, Wu C, Guo W, Xie Y, Li S, Liu W, Xu C, Li H, Cao P, Yang Y, Wang X, Chang A, Feng Y, Hao J
J Exp Clin Cancer Res 2023 Sep 11;42(1):238. doi: 10.1186/s13046-023-02814-x. PMID: 37697370Free PMC Article
Pediatric ankle injuries: utilizing the Dias-Tachdjian classification.
Pomeranz CB, Bartolotta RJ
Skeletal Radiol 2020 Apr;49(4):521-530. Epub 2019 Dec 2 doi: 10.1007/s00256-019-03356-0. PMID: 31792557
Peritonsillar abscess: clinical aspects of microbiology, risk factors, and the association with parapharyngeal abscess.
Klug TE
Dan Med J 2017 Mar;64(3) PMID: 28260599
Closing the growth plate: a review of indications and surgical options.
Ruzbarsky JJ, Goodbody C, Dodwell E
Curr Opin Pediatr 2017 Feb;29(1):80-86. doi: 10.1097/MOP.0000000000000438. PMID: 27845969
Ollier disease.
Silve C, Jüppner H
Orphanet J Rare Dis 2006 Sep 22;1:37. doi: 10.1186/1750-1172-1-37. PMID: 16995932Free PMC Article

Clinical prediction guides

Combination of RUNX1 inhibitor and gemcitabine mitigates chemo-resistance in pancreatic ductal adenocarcinoma by modulating BiP/PERK/eIF2α-axis-mediated endoplasmic reticulum stress.
She C, Wu C, Guo W, Xie Y, Li S, Liu W, Xu C, Li H, Cao P, Yang Y, Wang X, Chang A, Feng Y, Hao J
J Exp Clin Cancer Res 2023 Sep 11;42(1):238. doi: 10.1186/s13046-023-02814-x. PMID: 37697370Free PMC Article
Efficacy and Safety of "Sleeper Plate" in Temporary Hemiepiphysiodesis and the Observation of "Tethering".
Gerges M, Messner J, Lim B, Chhina H, Cooper A
J Pediatr Orthop 2022 Aug 1;42(7):e762-e766. Epub 2022 May 20 doi: 10.1097/BPO.0000000000002184. PMID: 35605208
Peritonsillar abscess: clinical aspects of microbiology, risk factors, and the association with parapharyngeal abscess.
Klug TE
Dan Med J 2017 Mar;64(3) PMID: 28260599
Closing the growth plate: a review of indications and surgical options.
Ruzbarsky JJ, Goodbody C, Dodwell E
Curr Opin Pediatr 2017 Feb;29(1):80-86. doi: 10.1097/MOP.0000000000000438. PMID: 27845969
Hypochondrogenesis.
Maroteaux P, Stanescu V, Stanescu R
Eur J Pediatr 1983 Oct;141(1):14-22. doi: 10.1007/BF00445662. PMID: 6641761

Recent systematic reviews

How does the cam morphology develop in athletes? A systematic review and meta-analysis.
Pettit M, Doran C, Singh Y, Saito M, Sunil Kumar KH, Khanduja V
Osteoarthritis Cartilage 2021 Aug;29(8):1117-1129. Epub 2021 May 11 doi: 10.1016/j.joca.2021.02.572. PMID: 33989785

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...