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Recurrent Nasal Type Extranodal NK/T-Cell Lymphoma

MedGen UID:
163128
•Concept ID:
C0854143
•
Neoplastic Process
Synonyms: Recurrent Angiocentric Lymphoma; Relapsed Angiocentric Lymphoma; Relapsed Nasal Type NK/T-Cell Lymphoma

Definition

The reemergence of nasal type extranodal NK/T-cell lymphoma after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Nasal Type Extranodal NK/T-Cell Lymphoma

Professional guidelines

PubMed

Extranodal NK/T-cell lymphoma: Updates in biology and management strategies.
Yamaguchi M, Oguchi M, Suzuki R
Best Pract Res Clin Haematol 2018 Sep;31(3):315-321. Epub 2018 Jul 3 doi: 10.1016/j.beha.2018.07.002. PMID: 30213402
Advances in the treatment of extranodal NK/T-cell lymphoma, nasal type.
Yamaguchi M, Suzuki R, Oguchi M
Blood 2018 Jun 7;131(23):2528-2540. Epub 2018 Mar 30 doi: 10.1182/blood-2017-12-791418. PMID: 29602763
Diagnosis and management of extranodal NK/T cell lymphoma nasal type.
Tse E, Kwong YL
Expert Rev Hematol 2016 Sep;9(9):861-71. Epub 2016 Jul 8 doi: 10.1080/17474086.2016.1206465. PMID: 27347812

Recent clinical studies

Etiology

Genomic profiling identifies distinct genetic subtypes in extra-nodal natural killer/T-cell lymphoma.
Dong G, Liu X, Wang L, Yin W, Bouska A, Gong Q, Shetty K, Chen L, Sharma S, Zhang J, Lome-Maldonado C, Quintanilla-Martinez L, Li Y, Song JY, Zhang W, Shi Y, Wang J, Kong L, Wu X, Wang J, Liu HG, Kong L, Sun W, Liu W, Wang L, McKeithan TW, Iqbal J, Chan WC
Leukemia 2022 Aug;36(8):2064-2075. Epub 2022 Jun 13 doi: 10.1038/s41375-022-01623-z. PMID: 35697790Free PMC Article
Mutational profile and EBV strains of extranodal NK/T-cell lymphoma, nasal type in Latin America.
Montes-Mojarro IA, Chen BJ, Ramirez-Ibarguen AF, Quezada-Fiallos CM, Pérez-Báez WB, Dueñas D, Casavilca-Zambrano S, Ortiz-Mayor M, Rojas-Bilbao E, García-Rivello H, Metrebian MF, Narbaitz M, Barrionuevo C, Lome-Maldonado C, Bonzheim I, Fend F, Steinhilber J, Quintanilla-Martinez L
Mod Pathol 2020 May;33(5):781-791. Epub 2019 Dec 10 doi: 10.1038/s41379-019-0415-5. PMID: 31822801
Extranodal NK/T-cell lymphoma: Updates in biology and management strategies.
Yamaguchi M, Oguchi M, Suzuki R
Best Pract Res Clin Haematol 2018 Sep;31(3):315-321. Epub 2018 Jul 3 doi: 10.1016/j.beha.2018.07.002. PMID: 30213402
Phase II study of SMILE chemotherapy for newly diagnosed stage IV, relapsed, or refractory extranodal natural killer (NK)/T-cell lymphoma, nasal type: the NK-Cell Tumor Study Group study.
Yamaguchi M, Kwong YL, Kim WS, Maeda Y, Hashimoto C, Suh C, Izutsu K, Ishida F, Isobe Y, Sueoka E, Suzumiya J, Kodama T, Kimura H, Hyo R, Nakamura S, Oshimi K, Suzuki R
J Clin Oncol 2011 Nov 20;29(33):4410-6. Epub 2011 Oct 11 doi: 10.1200/JCO.2011.35.6287. PMID: 21990393
Extranodal natural killer/T-cell lymphoma: advances in the management.
Jaccard A, Hermine O
Curr Opin Oncol 2011 Sep;23(5):429-35. doi: 10.1097/CCO.0b013e328349aba6. PMID: 21743325

Diagnosis

Nasal-type extranodal NK/T-cell lymphoma presenting as recurrent periorbital cellulitis.
Hussein MA, Boyle S, Abdulrahman S, Fennessy B
BMJ Case Rep 2021 Apr 1;14(4) doi: 10.1136/bcr-2020-238113. PMID: 33795266Free PMC Article
NK-Cell Lymphomas.
Chihara D, Oki Y
Cancer Treat Res 2019;176:163-184. doi: 10.1007/978-3-319-99716-2_8. PMID: 30596218
Advances in the treatment of extranodal NK/T-cell lymphoma, nasal type.
Yamaguchi M, Suzuki R, Oguchi M
Blood 2018 Jun 7;131(23):2528-2540. Epub 2018 Mar 30 doi: 10.1182/blood-2017-12-791418. PMID: 29602763
Diagnosis and management of extranodal NK/T cell lymphoma nasal type.
Tse E, Kwong YL
Expert Rev Hematol 2016 Sep;9(9):861-71. Epub 2016 Jul 8 doi: 10.1080/17474086.2016.1206465. PMID: 27347812
Phase II study of SMILE chemotherapy for newly diagnosed stage IV, relapsed, or refractory extranodal natural killer (NK)/T-cell lymphoma, nasal type: the NK-Cell Tumor Study Group study.
Yamaguchi M, Kwong YL, Kim WS, Maeda Y, Hashimoto C, Suh C, Izutsu K, Ishida F, Isobe Y, Sueoka E, Suzumiya J, Kodama T, Kimura H, Hyo R, Nakamura S, Oshimi K, Suzuki R
J Clin Oncol 2011 Nov 20;29(33):4410-6. Epub 2011 Oct 11 doi: 10.1200/JCO.2011.35.6287. PMID: 21990393

Therapy

Extranodal NK/T-cell lymphoma: Updates in biology and management strategies.
Yamaguchi M, Oguchi M, Suzuki R
Best Pract Res Clin Haematol 2018 Sep;31(3):315-321. Epub 2018 Jul 3 doi: 10.1016/j.beha.2018.07.002. PMID: 30213402
Advances in the treatment of extranodal NK/T-cell lymphoma, nasal type.
Yamaguchi M, Suzuki R, Oguchi M
Blood 2018 Jun 7;131(23):2528-2540. Epub 2018 Mar 30 doi: 10.1182/blood-2017-12-791418. PMID: 29602763
Pathogenesis and treatment of extranodal natural killer/T-cell lymphoma.
Suzuki R
Semin Hematol 2014 Jan;51(1):42-51. Epub 2013 Nov 15 doi: 10.1053/j.seminhematol.2013.11.007. PMID: 24468315
Phase II study of SMILE chemotherapy for newly diagnosed stage IV, relapsed, or refractory extranodal natural killer (NK)/T-cell lymphoma, nasal type: the NK-Cell Tumor Study Group study.
Yamaguchi M, Kwong YL, Kim WS, Maeda Y, Hashimoto C, Suh C, Izutsu K, Ishida F, Isobe Y, Sueoka E, Suzumiya J, Kodama T, Kimura H, Hyo R, Nakamura S, Oshimi K, Suzuki R
J Clin Oncol 2011 Nov 20;29(33):4410-6. Epub 2011 Oct 11 doi: 10.1200/JCO.2011.35.6287. PMID: 21990393
Extranodal natural killer/T-cell lymphoma: advances in the management.
Jaccard A, Hermine O
Curr Opin Oncol 2011 Sep;23(5):429-35. doi: 10.1097/CCO.0b013e328349aba6. PMID: 21743325

Prognosis

Nasal-type extranodal NK/T-cell lymphoma presenting as recurrent periorbital cellulitis.
Hussein MA, Boyle S, Abdulrahman S, Fennessy B
BMJ Case Rep 2021 Apr 1;14(4) doi: 10.1136/bcr-2020-238113. PMID: 33795266Free PMC Article
Extranodal NK/T-cell lymphoma: Updates in biology and management strategies.
Yamaguchi M, Oguchi M, Suzuki R
Best Pract Res Clin Haematol 2018 Sep;31(3):315-321. Epub 2018 Jul 3 doi: 10.1016/j.beha.2018.07.002. PMID: 30213402
Diagnosis and management of extranodal NK/T cell lymphoma nasal type.
Tse E, Kwong YL
Expert Rev Hematol 2016 Sep;9(9):861-71. Epub 2016 Jul 8 doi: 10.1080/17474086.2016.1206465. PMID: 27347812
Pathogenesis and treatment of extranodal natural killer/T-cell lymphoma.
Suzuki R
Semin Hematol 2014 Jan;51(1):42-51. Epub 2013 Nov 15 doi: 10.1053/j.seminhematol.2013.11.007. PMID: 24468315
Extranodal natural killer/T-cell lymphoma: advances in the management.
Jaccard A, Hermine O
Curr Opin Oncol 2011 Sep;23(5):429-35. doi: 10.1097/CCO.0b013e328349aba6. PMID: 21743325

Clinical prediction guides

Extranodal nasal-type NK/T lymphoma treated with chemotherapy and radiotherapy: case series from a European tertiary referral center and review of the literature.
Porte J, Hennequin C, Krizch D, Vercellino L, Guillerm S, Thieblemont C, Quéro L
Strahlenther Onkol 2024 May;200(5):434-443. Epub 2023 Nov 9 doi: 10.1007/s00066-023-02165-8. PMID: 37945929
DDGP vs. SMILE in Relapsed/Refractory Extranodal Natural Killer/T-cell Lymphoma, Nasal Type: A Retrospective Study of 54 Patients.
Wang X, Hu J, Dong M, Ding M, Zhu L, Wu J, Sun Z, Li X, Zhang L, Li L, Wang X, Fu X, Wang G, Chen Q, Zhang M, Zhang X
Clin Transl Sci 2021 Jan;14(1):405-411. Epub 2020 Oct 12 doi: 10.1111/cts.12893. PMID: 33045134Free PMC Article
Mutational profile and EBV strains of extranodal NK/T-cell lymphoma, nasal type in Latin America.
Montes-Mojarro IA, Chen BJ, Ramirez-Ibarguen AF, Quezada-Fiallos CM, Pérez-Báez WB, Dueñas D, Casavilca-Zambrano S, Ortiz-Mayor M, Rojas-Bilbao E, García-Rivello H, Metrebian MF, Narbaitz M, Barrionuevo C, Lome-Maldonado C, Bonzheim I, Fend F, Steinhilber J, Quintanilla-Martinez L
Mod Pathol 2020 May;33(5):781-791. Epub 2019 Dec 10 doi: 10.1038/s41379-019-0415-5. PMID: 31822801
Pathogenesis and treatment of extranodal natural killer/T-cell lymphoma.
Suzuki R
Semin Hematol 2014 Jan;51(1):42-51. Epub 2013 Nov 15 doi: 10.1053/j.seminhematol.2013.11.007. PMID: 24468315
Phase II study of SMILE chemotherapy for newly diagnosed stage IV, relapsed, or refractory extranodal natural killer (NK)/T-cell lymphoma, nasal type: the NK-Cell Tumor Study Group study.
Yamaguchi M, Kwong YL, Kim WS, Maeda Y, Hashimoto C, Suh C, Izutsu K, Ishida F, Isobe Y, Sueoka E, Suzumiya J, Kodama T, Kimura H, Hyo R, Nakamura S, Oshimi K, Suzuki R
J Clin Oncol 2011 Nov 20;29(33):4410-6. Epub 2011 Oct 11 doi: 10.1200/JCO.2011.35.6287. PMID: 21990393

Recent systematic reviews

The optimal timing of radiotherapy in the combination treatment of limited-stage extranodal natural killer/T-cell lymphoma, nasal type: an updated meta-analysis.
Cui Y, Yao Y, Chen M, Jiang Y, Ren Q
Ann Hematol 2021 Dec;100(12):2889-2900. Epub 2021 Oct 27 doi: 10.1007/s00277-021-04700-y. PMID: 34708280

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