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Recurrent Lobular Breast Carcinoma

MedGen UID:
1652341
•Concept ID:
C4727372
•
Neoplastic Process

Definition

The reemergence of lobular breast carcinoma after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Lobular Breast Carcinoma

Professional guidelines

PubMed

Diagnosis, characteristics, and treatment of breast carcinomas within benign fibroepithelial tumors.
Saimura M, Koga K, Anan K, Mitsuyama S, Tamiya S
Breast Cancer 2018 Jul;25(4):470-478. Epub 2018 Feb 19 doi: 10.1007/s12282-018-0847-7. PMID: 29460095
Genotype-Phenotype Correlations in Breast Cancer.
Marotti JD, Schnitt SJ
Surg Pathol Clin 2018 Mar;11(1):199-211. Epub 2017 Dec 15 doi: 10.1016/j.path.2017.09.008. PMID: 29413657
Treatment of breast cancer.
Maughan KL, Lutterbie MA, Ham PS
Am Fam Physician 2010 Jun 1;81(11):1339-46. PMID: 20521754

Recent clinical studies

Etiology

Lobular Carcinoma of the Breast and Utility of Oncotype Dx®: a Retrospective Decision Impact Analysis.
Barni S, Fabi A, Petrelli F
Clin Breast Cancer 2023 Apr;23(3):e173-e174. Epub 2022 Dec 14 doi: 10.1016/j.clbc.2022.12.005. PMID: 36586733
Invasive lobular carcinoma: an understudied emergent subtype of breast cancer.
Mouabbi JA, Hassan A, Lim B, Hortobagyi GN, Tripathy D, Layman RM
Breast Cancer Res Treat 2022 Jun;193(2):253-264. Epub 2022 Mar 26 doi: 10.1007/s10549-022-06572-w. PMID: 35347549
Invasive lobular carcinoma of the breast: clinicopathological features and patient outcomes.
Bozkurt E, Kaya C, Ucak R, Demircioglu MK, Guven O, Mihmanli M
Ann Ital Chir 2021;92:494-499. PMID: 34795114
Eight-year follow up result of the OTOASOR trial: The Optimal Treatment Of the Axilla - Surgery Or Radiotherapy after positive sentinel lymph node biopsy in early-stage breast cancer: A randomized, single centre, phase III, non-inferiority trial.
Sávolt Á, Péley G, Polgár C, Udvarhelyi N, Rubovszky G, Kovács E, Győrffy B, Kásler M, Mátrai Z
Eur J Surg Oncol 2017 Apr;43(4):672-679. Epub 2017 Jan 16 doi: 10.1016/j.ejso.2016.12.011. PMID: 28139362
Lobular carcinoma in situ and invasive lobular cancer of the breast.
Cocquyt V, Van Belle S
Curr Opin Obstet Gynecol 2005 Feb;17(1):55-60. doi: 10.1097/00001703-200502000-00010. PMID: 15711412

Diagnosis

Lobular Carcinoma of the Breast and Utility of Oncotype Dx®: a Retrospective Decision Impact Analysis.
Barni S, Fabi A, Petrelli F
Clin Breast Cancer 2023 Apr;23(3):e173-e174. Epub 2022 Dec 14 doi: 10.1016/j.clbc.2022.12.005. PMID: 36586733
Clinicopathological Features and Outcomes Comparing Patients With Invasive Ductal and Lobular Breast Cancer.
Oesterreich S, Nasrazadani A, Zou J, Carleton N, Onger T, Wright MD, Li Y, Demanelis K, Ramaswamy B, Tseng G, Lee AV, Williams N, Kruse M
J Natl Cancer Inst 2022 Nov 14;114(11):1511-1522. doi: 10.1093/jnci/djac157. PMID: 36239760Free PMC Article
Invasive lobular carcinoma: an understudied emergent subtype of breast cancer.
Mouabbi JA, Hassan A, Lim B, Hortobagyi GN, Tripathy D, Layman RM
Breast Cancer Res Treat 2022 Jun;193(2):253-264. Epub 2022 Mar 26 doi: 10.1007/s10549-022-06572-w. PMID: 35347549
Problematic breast tumors reassessed in light of novel molecular data.
Pareja F, Weigelt B, Reis-Filho JS
Mod Pathol 2021 Jan;34(Suppl 1):38-47. Epub 2020 Oct 6 doi: 10.1038/s41379-020-00693-7. PMID: 33024304Free PMC Article
Lobular Breast Cancer: Different Disease, Different Algorithms?
Mamtani A, King TA
Surg Oncol Clin N Am 2018 Jan;27(1):81-94. doi: 10.1016/j.soc.2017.07.005. PMID: 29132567

Therapy

Randomized Placebo Controlled Trial of Low-Dose Tamoxifen to Prevent Recurrence in Breast Noninvasive Neoplasia: A 10-Year Follow-Up of TAM-01 Study.
Lazzeroni M, Puntoni M, Guerrieri-Gonzaga A, Serrano D, Boni L, Buttiron Webber T, Fava M, Briata IM, Giordano L, Digennaro M, Cortesi L, Falcini F, Serra P, Avino F, Millo F, Cagossi K, Gallerani E, De Simone A, Cariello A, Aprile G, Renne M, Bonanni B, DeCensi A
J Clin Oncol 2023 Jun 10;41(17):3116-3121. Epub 2023 Mar 14 doi: 10.1200/JCO.22.02900. PMID: 36917758
Randomized Placebo Controlled Trial of Low-Dose Tamoxifen to Prevent Local and Contralateral Recurrence in Breast Intraepithelial Neoplasia.
DeCensi A, Puntoni M, Guerrieri-Gonzaga A, Caviglia S, Avino F, Cortesi L, Taverniti C, Pacquola MG, Falcini F, Gulisano M, Digennaro M, Cariello A, Cagossi K, Pinotti G, Lazzeroni M, Serrano D, Branchi D, Campora S, Petrera M, Buttiron Webber T, Boni L, Bonanni B
J Clin Oncol 2019 Jul 1;37(19):1629-1637. Epub 2019 Apr 11 doi: 10.1200/JCO.18.01779. PMID: 30973790Free PMC Article
Eight-year follow up result of the OTOASOR trial: The Optimal Treatment Of the Axilla - Surgery Or Radiotherapy after positive sentinel lymph node biopsy in early-stage breast cancer: A randomized, single centre, phase III, non-inferiority trial.
Sávolt Á, Péley G, Polgár C, Udvarhelyi N, Rubovszky G, Kovács E, Győrffy B, Kásler M, Mátrai Z
Eur J Surg Oncol 2017 Apr;43(4):672-679. Epub 2017 Jan 16 doi: 10.1016/j.ejso.2016.12.011. PMID: 28139362
Estrogen receptors in breast carcinogenesis and endocrine therapy.
Huang B, Warner M, Gustafsson JÅ
Mol Cell Endocrinol 2015 Dec 15;418 Pt 3:240-4. Epub 2014 Nov 26 doi: 10.1016/j.mce.2014.11.015. PMID: 25433206
Treatment of breast cancer.
Maughan KL, Lutterbie MA, Ham PS
Am Fam Physician 2010 Jun 1;81(11):1339-46. PMID: 20521754

Prognosis

Lobular Carcinoma of the Breast and Utility of Oncotype Dx®: a Retrospective Decision Impact Analysis.
Barni S, Fabi A, Petrelli F
Clin Breast Cancer 2023 Apr;23(3):e173-e174. Epub 2022 Dec 14 doi: 10.1016/j.clbc.2022.12.005. PMID: 36586733
Invasive lobular carcinoma: an understudied emergent subtype of breast cancer.
Mouabbi JA, Hassan A, Lim B, Hortobagyi GN, Tripathy D, Layman RM
Breast Cancer Res Treat 2022 Jun;193(2):253-264. Epub 2022 Mar 26 doi: 10.1007/s10549-022-06572-w. PMID: 35347549
Lobular Breast Cancer: Different Disease, Different Algorithms?
Mamtani A, King TA
Surg Oncol Clin N Am 2018 Jan;27(1):81-94. doi: 10.1016/j.soc.2017.07.005. PMID: 29132567
Eight-year follow up result of the OTOASOR trial: The Optimal Treatment Of the Axilla - Surgery Or Radiotherapy after positive sentinel lymph node biopsy in early-stage breast cancer: A randomized, single centre, phase III, non-inferiority trial.
Sávolt Á, Péley G, Polgár C, Udvarhelyi N, Rubovszky G, Kovács E, Győrffy B, Kásler M, Mátrai Z
Eur J Surg Oncol 2017 Apr;43(4):672-679. Epub 2017 Jan 16 doi: 10.1016/j.ejso.2016.12.011. PMID: 28139362
Lobular carcinoma in situ and invasive lobular cancer of the breast.
Cocquyt V, Van Belle S
Curr Opin Obstet Gynecol 2005 Feb;17(1):55-60. doi: 10.1097/00001703-200502000-00010. PMID: 15711412

Clinical prediction guides

Absence of lobular carcinoma in situ is a poor prognostic marker in invasive lobular carcinoma.
Mouabbi JA, Raghavendra AS, Bassett RL Jr, Christgen M, Middleton L, Teshome M, Nasrazadani A, Hortobagyi G, Hassan A, Tripathy D, Layman RM
Eur J Cancer 2023 Sep;191:113250. Epub 2023 Jul 22 doi: 10.1016/j.ejca.2023.113250. PMID: 37573674Free PMC Article
Lobular Carcinoma of the Breast and Utility of Oncotype Dx®: a Retrospective Decision Impact Analysis.
Barni S, Fabi A, Petrelli F
Clin Breast Cancer 2023 Apr;23(3):e173-e174. Epub 2022 Dec 14 doi: 10.1016/j.clbc.2022.12.005. PMID: 36586733
Clinicopathological Features and Outcomes Comparing Patients With Invasive Ductal and Lobular Breast Cancer.
Oesterreich S, Nasrazadani A, Zou J, Carleton N, Onger T, Wright MD, Li Y, Demanelis K, Ramaswamy B, Tseng G, Lee AV, Williams N, Kruse M
J Natl Cancer Inst 2022 Nov 14;114(11):1511-1522. doi: 10.1093/jnci/djac157. PMID: 36239760Free PMC Article
Transcriptomic and genomic features of invasive lobular breast cancer.
Desmedt C, Zoppoli G, Sotiriou C, Salgado R
Semin Cancer Biol 2017 Jun;44:98-105. Epub 2017 Apr 8 doi: 10.1016/j.semcancer.2017.03.007. PMID: 28400203
Breast Cancer-Major changes in the American Joint Committee on Cancer eighth edition cancer staging manual.
Giuliano AE, Connolly JL, Edge SB, Mittendorf EA, Rugo HS, Solin LJ, Weaver DL, Winchester DJ, Hortobagyi GN
CA Cancer J Clin 2017 Jul 8;67(4):290-303. Epub 2017 Mar 14 doi: 10.3322/caac.21393. PMID: 28294295

Recent systematic reviews

Impact of lobular carcinoma in situ on local recurrence in breast cancer treated with breast conservation therapy: a systematic review and meta-analysis.
Harris CG, Eslick GD
ANZ J Surg 2021 Sep;91(9):1696-1703. Epub 2021 Feb 26 doi: 10.1111/ans.16671. PMID: 33634956
Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer.
Moran MS, Schnitt SJ, Giuliano AE, Harris JR, Khan SA, Horton J, Klimberg S, Chavez-MacGregor M, Freedman G, Houssami N, Johnson PL, Morrow M
Int J Radiat Oncol Biol Phys 2014 Mar 1;88(3):553-64. doi: 10.1016/j.ijrobp.2013.11.012. PMID: 24521674Free PMC Article
Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer.
Moran MS, Schnitt SJ, Giuliano AE, Harris JR, Khan SA, Horton J, Klimberg S, Chavez-MacGregor M, Freedman G, Houssami N, Johnson PL, Morrow M; Society of Surgical Oncology; American Society for Radiation Oncology
J Clin Oncol 2014 May 10;32(14):1507-15. Epub 2014 Feb 10 doi: 10.1200/JCO.2013.53.3935. PMID: 24516019
Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer.
Moran MS, Schnitt SJ, Giuliano AE, Harris JR, Khan SA, Horton J, Klimberg S, Chavez-MacGregor M, Freedman G, Houssami N, Johnson PL, Morrow M
Ann Surg Oncol 2014 Mar;21(3):704-16. Epub 2014 Feb 10 doi: 10.1245/s10434-014-3481-4. PMID: 24515565

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