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Infectious panuveitis

MedGen UID:
1684863
Concept ID:
C5230354
Disease or Syndrome
Synonyms: infectious panuveitis; Panuveitis due to infectious disease
SNOMED CT: Infectious panuveitis (789116000); Panuveitis due to infectious disease (789116000)
 
Monarch Initiative: MONDO:0017211
Orphanet: ORPHA279925

Definition

A rare ophthalmic disorder characterized by generalized inflammation of all parts of the uveal tract (iris, ciliary body, and choroid), simultaneously involving adjacent vitreous and retina, without any predominant site of inflammation, due to viral, bacterial, fungal, or parasitic infections. Clinical symptoms include pain, photophobia, redness, blurring of vision, and floaters. Signs on examination are lid edema, ciliary injection, chemosis, keratic precipitates, cells in the anterior chamber, hypopyon, iris nodules and neovascularization, posterior synechiae, macular edema, vitreous and retinal hemorrhage, and retinal detachment, among others. Complications may result in visual loss. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInfectious panuveitis

Professional guidelines

PubMed

Arevalo JF, Lasave AF, Gupta V, Kozak I, Al Shamsi HN, Al Suliman SM, Al Rushood AA, Al-Zahrani YA, Al-Mahmood AM, Al Dhibi HA; KKESH Uveitis Survey Study Group
Ocul Immunol Inflamm 2019;27(8):1296-1304. Epub 2018 Oct 10 doi: 10.1080/09273948.2018.1523436. PMID: 30303435

Recent clinical studies

Etiology

Tungsattayathitthan U, Tesavibul N, Choopong P, Treeratsakulchai C, Ngathaweesuk Y, Sanphan W, Boonsopon S
Sci Rep 2024 Jan 25;14(1):2179. doi: 10.1038/s41598-024-52526-1. PMID: 38273077Free PMC Article
Chau VQ, Hinkle JW, Wu CY, Pakravan P, Volante V, Sengillo JD, Staropoli PC, Miller D, Yannuzzi NA, Albini TA
Retina 2024 May 1;44(5):909-915. Epub 2024 Apr 18 doi: 10.1097/IAE.0000000000004037. PMID: 38271688Free PMC Article
Arevalo JF, Lasave AF, Gupta V, Kozak I, Al Shamsi HN, Al Suliman SM, Al Rushood AA, Al-Zahrani YA, Al-Mahmood AM, Al Dhibi HA; KKESH Uveitis Survey Study Group
Ocul Immunol Inflamm 2019;27(8):1296-1304. Epub 2018 Oct 10 doi: 10.1080/09273948.2018.1523436. PMID: 30303435

Diagnosis

Tungsattayathitthan U, Tesavibul N, Choopong P, Treeratsakulchai C, Ngathaweesuk Y, Sanphan W, Boonsopon S
Sci Rep 2024 Jan 25;14(1):2179. doi: 10.1038/s41598-024-52526-1. PMID: 38273077Free PMC Article
Chau VQ, Hinkle JW, Wu CY, Pakravan P, Volante V, Sengillo JD, Staropoli PC, Miller D, Yannuzzi NA, Albini TA
Retina 2024 May 1;44(5):909-915. Epub 2024 Apr 18 doi: 10.1097/IAE.0000000000004037. PMID: 38271688Free PMC Article
Arevalo JF, Lasave AF, Gupta V, Kozak I, Al Shamsi HN, Al Suliman SM, Al Rushood AA, Al-Zahrani YA, Al-Mahmood AM, Al Dhibi HA; KKESH Uveitis Survey Study Group
Ocul Immunol Inflamm 2019;27(8):1296-1304. Epub 2018 Oct 10 doi: 10.1080/09273948.2018.1523436. PMID: 30303435

Therapy

Tungsattayathitthan U, Tesavibul N, Choopong P, Treeratsakulchai C, Ngathaweesuk Y, Sanphan W, Boonsopon S
Sci Rep 2024 Jan 25;14(1):2179. doi: 10.1038/s41598-024-52526-1. PMID: 38273077Free PMC Article
Rush R, Sheth S
Indian J Ophthalmol 2012 Mar-Apr;60(2):141-3. doi: 10.4103/0301-4738.94059. PMID: 22446913Free PMC Article

Prognosis

Arevalo JF, Lasave AF, Gupta V, Kozak I, Al Shamsi HN, Al Suliman SM, Al Rushood AA, Al-Zahrani YA, Al-Mahmood AM, Al Dhibi HA; KKESH Uveitis Survey Study Group
Ocul Immunol Inflamm 2019;27(8):1296-1304. Epub 2018 Oct 10 doi: 10.1080/09273948.2018.1523436. PMID: 30303435

Supplemental Content

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