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Increased Bone Remodeling

MedGen UID:
1709969
Concept ID:
C5237710
Finding

Definition

Increase in the removal of mineralized bone matrix and/or mature bone and the formation of new bone. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased Bone Remodeling

Professional guidelines

PubMed

Rajput S, Dutta A, Rajender S, Mithal A, Chattopadhyay N
Front Endocrinol (Lausanne) 2023;14:1098841. Epub 2023 Feb 2 doi: 10.3389/fendo.2023.1098841. PMID: 36817591Free PMC Article
Ferrari S, Bianchi ML, Eisman JA, Foldes AJ, Adami S, Wahl DA, Stepan JJ, de Vernejoul MC, Kaufman JM; IOF Committee of Scientific Advisors Working Group on Osteoporosis Pathophysiology
Osteoporos Int 2012 Dec;23(12):2735-48. Epub 2012 Jun 9 doi: 10.1007/s00198-012-2030-x. PMID: 22684497
Tiegs RD
Clin Ther 1997 Nov-Dec;19(6):1309-29; discussion 1523-4. doi: 10.1016/s0149-2918(97)80007-0. PMID: 9444442

Recent clinical studies

Etiology

Rajput S, Dutta A, Rajender S, Mithal A, Chattopadhyay N
Front Endocrinol (Lausanne) 2023;14:1098841. Epub 2023 Feb 2 doi: 10.3389/fendo.2023.1098841. PMID: 36817591Free PMC Article
Nieckula P, Stempniewicz A, Tubaja M
Dent Med Probl 2018 Oct-Dec;55(4):425-429. doi: 10.17219/dmp/99021. PMID: 30521152
Hughes JM, Popp KL, Yanovich R, Bouxsein ML, Matheny RW Jr
Exp Biol Med (Maywood) 2017 May;242(9):897-906. Epub 2016 Aug 5 doi: 10.1177/1535370216661646. PMID: 27496801Free PMC Article
Khanna S, Pillai KK, Vohora D
Drug Discov Today 2009 Apr;14(7-8):428-35. Epub 2009 Jan 31 doi: 10.1016/j.drudis.2009.01.004. PMID: 19187798
Gennari C, Martini G, Nuti R
Aging (Milano) 1998 Jun;10(3):214-24. doi: 10.1007/BF03339655. PMID: 9801731

Diagnosis

Xie D, Bai Z, Zhou G, Li K, Ding J, Zhang H, Jiang J
Chem Biol Drug Des 2023 Dec;102(6):1478-1488. Epub 2023 Sep 15 doi: 10.1111/cbdd.14339. PMID: 37712455
Hsu E
Curr Opin Endocrinol Diabetes Obes 2019 Dec;26(6):329-334. doi: 10.1097/MED.0000000000000503. PMID: 31574000
Ferrari S, Bianchi ML, Eisman JA, Foldes AJ, Adami S, Wahl DA, Stepan JJ, de Vernejoul MC, Kaufman JM; IOF Committee of Scientific Advisors Working Group on Osteoporosis Pathophysiology
Osteoporos Int 2012 Dec;23(12):2735-48. Epub 2012 Jun 9 doi: 10.1007/s00198-012-2030-x. PMID: 22684497
Tiegs RD
Clin Ther 1997 Nov-Dec;19(6):1309-29; discussion 1523-4. doi: 10.1016/s0149-2918(97)80007-0. PMID: 9444442
Schauwecker DS
AJR Am J Roentgenol 1992 Jan;158(1):9-18. doi: 10.2214/ajr.158.1.1727365. PMID: 1727365

Therapy

Rajput S, Dutta A, Rajender S, Mithal A, Chattopadhyay N
Front Endocrinol (Lausanne) 2023;14:1098841. Epub 2023 Feb 2 doi: 10.3389/fendo.2023.1098841. PMID: 36817591Free PMC Article
Hsu E
Curr Opin Endocrinol Diabetes Obes 2019 Dec;26(6):329-334. doi: 10.1097/MED.0000000000000503. PMID: 31574000
Nieckula P, Stempniewicz A, Tubaja M
Dent Med Probl 2018 Oct-Dec;55(4):425-429. doi: 10.17219/dmp/99021. PMID: 30521152
Khanna S, Pillai KK, Vohora D
Drug Discov Today 2009 Apr;14(7-8):428-35. Epub 2009 Jan 31 doi: 10.1016/j.drudis.2009.01.004. PMID: 19187798
Heaney RP
J Am Coll Nutr 2006 Jun;25(3 Suppl):271S-276S. doi: 10.1080/07315724.2006.10719577. PMID: 16772639

Prognosis

Xie D, Bai Z, Zhou G, Li K, Ding J, Zhang H, Jiang J
Chem Biol Drug Des 2023 Dec;102(6):1478-1488. Epub 2023 Sep 15 doi: 10.1111/cbdd.14339. PMID: 37712455
Michou L, Gamache P, Guertin JR, Tarride JE, Brown JP, Jean S
Bone 2023 Nov;176:116895. Epub 2023 Sep 6 doi: 10.1016/j.bone.2023.116895. PMID: 37683713
Loef M, van Beest S, Kroon FPB, Bloem JL, Dekkers OM, Reijnierse M, Schoones JW, Kloppenburg M
Osteoarthritis Cartilage 2018 Aug;26(8):992-1002. Epub 2018 May 17 doi: 10.1016/j.joca.2018.05.007. PMID: 29777863
McNeilly T, McNally C, Finch M, Beringer T
Ulster Med J 2013 May;82(2):89-93. PMID: 24082286Free PMC Article
Mezquita-Raya P, Muñoz-Torres M, Luna JD, Luna V, Lopez-Rodriguez F, Torres-Vela E, Escobar-Jiménez F
J Bone Miner Res 2001 Aug;16(8):1408-15. doi: 10.1359/jbmr.2001.16.8.1408. PMID: 11499863

Clinical prediction guides

Xie D, Bai Z, Zhou G, Li K, Ding J, Zhang H, Jiang J
Chem Biol Drug Des 2023 Dec;102(6):1478-1488. Epub 2023 Sep 15 doi: 10.1111/cbdd.14339. PMID: 37712455
Butscheidt S, von Kroge S, Stürznickel J, Beil FT, Gehrke T, Püschel K, Amling M, Hahn M, Rolvien T
J Bone Joint Surg Am 2021 Nov 3;103(21):1996-2005. doi: 10.2106/JBJS.20.01943. PMID: 34228665
Ferrari S, Bianchi ML, Eisman JA, Foldes AJ, Adami S, Wahl DA, Stepan JJ, de Vernejoul MC, Kaufman JM; IOF Committee of Scientific Advisors Working Group on Osteoporosis Pathophysiology
Osteoporos Int 2012 Dec;23(12):2735-48. Epub 2012 Jun 9 doi: 10.1007/s00198-012-2030-x. PMID: 22684497
Recker R, Lappe J, Davies KM, Heaney R
J Bone Miner Res 2004 Oct;19(10):1628-33. Epub 2004 Jul 21 doi: 10.1359/JBMR.040710. PMID: 15355557
Tiegs RD
Clin Ther 1997 Nov-Dec;19(6):1309-29; discussion 1523-4. doi: 10.1016/s0149-2918(97)80007-0. PMID: 9444442

Recent systematic reviews

Rajput S, Dutta A, Rajender S, Mithal A, Chattopadhyay N
Front Endocrinol (Lausanne) 2023;14:1098841. Epub 2023 Feb 2 doi: 10.3389/fendo.2023.1098841. PMID: 36817591Free PMC Article
Loef M, van Beest S, Kroon FPB, Bloem JL, Dekkers OM, Reijnierse M, Schoones JW, Kloppenburg M
Osteoarthritis Cartilage 2018 Aug;26(8):992-1002. Epub 2018 May 17 doi: 10.1016/j.joca.2018.05.007. PMID: 29777863

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