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Renal cortical interstitial inflammation

MedGen UID:
1713179
Concept ID:
C5397947
Pathologic Function
HPO: HP:0032946

Definition

Histopathological findings of inflammation of the renal interstitium involving fibrotic as well as non-fibrotic renal cortex, composed of lymphocytes, monocytes, plasma cells. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRenal cortical interstitial inflammation

Professional guidelines

PubMed

Mbengue M, Goumri N, Niang A
Clin Nephrol 2021 Jun;95(6):292-302. doi: 10.5414/CN110492. PMID: 33860756
Haas M, Loupy A, Lefaucheur C, Roufosse C, Glotz D, Seron D, Nankivell BJ, Halloran PF, Colvin RB, Akalin E, Alachkar N, Bagnasco S, Bouatou Y, Becker JU, Cornell LD, Duong van Huyen JP, Gibson IW, Kraus ES, Mannon RB, Naesens M, Nickeleit V, Nickerson P, Segev DL, Singh HK, Stegall M, Randhawa P, Racusen L, Solez K, Mengel M
Am J Transplant 2018 Feb;18(2):293-307. Epub 2018 Jan 21 doi: 10.1111/ajt.14625. PMID: 29243394Free PMC Article
Krishnan N, Perazella MA
Iran J Kidney Dis 2015 Jan;9(1):3-13. PMID: 25599729

Recent clinical studies

Etiology

Mehta S, Lightle A, Judson MA
Nephrol Dial Transplant 2023 Mar 31;38(4):803-810. doi: 10.1093/ndt/gfac219. PMID: 35867874
Sciascia S, Cozzi M, Barinotti A, Radin M, Cecchi I, Fenoglio R, Mancardi D, Wilson Jones G, Rossi D, Roccatello D
Int J Mol Sci 2022 Nov 18;23(22) doi: 10.3390/ijms232214317. PMID: 36430794Free PMC Article
Haas M, Loupy A, Lefaucheur C, Roufosse C, Glotz D, Seron D, Nankivell BJ, Halloran PF, Colvin RB, Akalin E, Alachkar N, Bagnasco S, Bouatou Y, Becker JU, Cornell LD, Duong van Huyen JP, Gibson IW, Kraus ES, Mannon RB, Naesens M, Nickeleit V, Nickerson P, Segev DL, Singh HK, Stegall M, Randhawa P, Racusen L, Solez K, Mengel M
Am J Transplant 2018 Feb;18(2):293-307. Epub 2018 Jan 21 doi: 10.1111/ajt.14625. PMID: 29243394Free PMC Article
Trimarchi H, Barratt J, Cattran DC, Cook HT, Coppo R, Haas M, Liu ZH, Roberts IS, Yuzawa Y, Zhang H, Feehally J; IgAN Classification Working Group of the International IgA Nephropathy Network and the Renal Pathology Society; Conference Participants
Kidney Int 2017 May;91(5):1014-1021. Epub 2017 Mar 22 doi: 10.1016/j.kint.2017.02.003. PMID: 28341274
Medapalli RK, He JC, Klotman PE
Curr Opin Nephrol Hypertens 2011 May;20(3):306-11. doi: 10.1097/MNH.0b013e328345359a. PMID: 21358326Free PMC Article

Diagnosis

Mehta S, Lightle A, Judson MA
Nephrol Dial Transplant 2023 Mar 31;38(4):803-810. doi: 10.1093/ndt/gfac219. PMID: 35867874
Zhu B, Liu WH, Lin Y, Li Q, Yu DR, Jiang F, Tang XL, Du YY, Yin JZ, Li XF, Zhong YZ, Wang WR, Sun Y, Zhang MJ, Gao YC, Yuan CY, Zhu CF, Cheng XX
Am J Nephrol 2022;53(6):455-469. Epub 2022 May 16 doi: 10.1159/000524585. PMID: 35576899
Mbengue M, Goumri N, Niang A
Clin Nephrol 2021 Jun;95(6):292-302. doi: 10.5414/CN110492. PMID: 33860756
Haas M, Loupy A, Lefaucheur C, Roufosse C, Glotz D, Seron D, Nankivell BJ, Halloran PF, Colvin RB, Akalin E, Alachkar N, Bagnasco S, Bouatou Y, Becker JU, Cornell LD, Duong van Huyen JP, Gibson IW, Kraus ES, Mannon RB, Naesens M, Nickeleit V, Nickerson P, Segev DL, Singh HK, Stegall M, Randhawa P, Racusen L, Solez K, Mengel M
Am J Transplant 2018 Feb;18(2):293-307. Epub 2018 Jan 21 doi: 10.1111/ajt.14625. PMID: 29243394Free PMC Article
Najafian B, Alpers CE, Fogo AB
Contrib Nephrol 2011;170:36-47. Epub 2011 Jun 9 doi: 10.1159/000324942. PMID: 21659756

Therapy

Mehta S, Lightle A, Judson MA
Nephrol Dial Transplant 2023 Mar 31;38(4):803-810. doi: 10.1093/ndt/gfac219. PMID: 35867874
Mbengue M, Goumri N, Niang A
Clin Nephrol 2021 Jun;95(6):292-302. doi: 10.5414/CN110492. PMID: 33860756
Haas M, Loupy A, Lefaucheur C, Roufosse C, Glotz D, Seron D, Nankivell BJ, Halloran PF, Colvin RB, Akalin E, Alachkar N, Bagnasco S, Bouatou Y, Becker JU, Cornell LD, Duong van Huyen JP, Gibson IW, Kraus ES, Mannon RB, Naesens M, Nickeleit V, Nickerson P, Segev DL, Singh HK, Stegall M, Randhawa P, Racusen L, Solez K, Mengel M
Am J Transplant 2018 Feb;18(2):293-307. Epub 2018 Jan 21 doi: 10.1111/ajt.14625. PMID: 29243394Free PMC Article
Trimarchi H, Barratt J, Cattran DC, Cook HT, Coppo R, Haas M, Liu ZH, Roberts IS, Yuzawa Y, Zhang H, Feehally J; IgAN Classification Working Group of the International IgA Nephropathy Network and the Renal Pathology Society; Conference Participants
Kidney Int 2017 May;91(5):1014-1021. Epub 2017 Mar 22 doi: 10.1016/j.kint.2017.02.003. PMID: 28341274
Fabrizi F, Donato F, Messa P
Minerva Urol Nefrol 2014 Jun;66(2):139-49. PMID: 24988205

Prognosis

Mehta S, Lightle A, Judson MA
Nephrol Dial Transplant 2023 Mar 31;38(4):803-810. doi: 10.1093/ndt/gfac219. PMID: 35867874
Sciascia S, Cozzi M, Barinotti A, Radin M, Cecchi I, Fenoglio R, Mancardi D, Wilson Jones G, Rossi D, Roccatello D
Int J Mol Sci 2022 Nov 18;23(22) doi: 10.3390/ijms232214317. PMID: 36430794Free PMC Article
Zhu B, Liu WH, Lin Y, Li Q, Yu DR, Jiang F, Tang XL, Du YY, Yin JZ, Li XF, Zhong YZ, Wang WR, Sun Y, Zhang MJ, Gao YC, Yuan CY, Zhu CF, Cheng XX
Am J Nephrol 2022;53(6):455-469. Epub 2022 May 16 doi: 10.1159/000524585. PMID: 35576899
Haas M, Loupy A, Lefaucheur C, Roufosse C, Glotz D, Seron D, Nankivell BJ, Halloran PF, Colvin RB, Akalin E, Alachkar N, Bagnasco S, Bouatou Y, Becker JU, Cornell LD, Duong van Huyen JP, Gibson IW, Kraus ES, Mannon RB, Naesens M, Nickeleit V, Nickerson P, Segev DL, Singh HK, Stegall M, Randhawa P, Racusen L, Solez K, Mengel M
Am J Transplant 2018 Feb;18(2):293-307. Epub 2018 Jan 21 doi: 10.1111/ajt.14625. PMID: 29243394Free PMC Article
Trimarchi H, Barratt J, Cattran DC, Cook HT, Coppo R, Haas M, Liu ZH, Roberts IS, Yuzawa Y, Zhang H, Feehally J; IgAN Classification Working Group of the International IgA Nephropathy Network and the Renal Pathology Society; Conference Participants
Kidney Int 2017 May;91(5):1014-1021. Epub 2017 Mar 22 doi: 10.1016/j.kint.2017.02.003. PMID: 28341274

Clinical prediction guides

Sciascia S, Cozzi M, Barinotti A, Radin M, Cecchi I, Fenoglio R, Mancardi D, Wilson Jones G, Rossi D, Roccatello D
Int J Mol Sci 2022 Nov 18;23(22) doi: 10.3390/ijms232214317. PMID: 36430794Free PMC Article
Zhu B, Liu WH, Lin Y, Li Q, Yu DR, Jiang F, Tang XL, Du YY, Yin JZ, Li XF, Zhong YZ, Wang WR, Sun Y, Zhang MJ, Gao YC, Yuan CY, Zhu CF, Cheng XX
Am J Nephrol 2022;53(6):455-469. Epub 2022 May 16 doi: 10.1159/000524585. PMID: 35576899
Trimarchi H, Barratt J, Cattran DC, Cook HT, Coppo R, Haas M, Liu ZH, Roberts IS, Yuzawa Y, Zhang H, Feehally J; IgAN Classification Working Group of the International IgA Nephropathy Network and the Renal Pathology Society; Conference Participants
Kidney Int 2017 May;91(5):1014-1021. Epub 2017 Mar 22 doi: 10.1016/j.kint.2017.02.003. PMID: 28341274
Marien TP, Miller NL
Minerva Urol Nefrol 2016 Dec;68(6):496-515. Epub 2016 Jul 21 PMID: 27441596
Krishnan N, Perazella MA
Iran J Kidney Dis 2015 Jan;9(1):3-13. PMID: 25599729

Recent systematic reviews

Corthier A, Jachiet M, Bertin D, Servais A, Barbet C, Bigot A, Doutre MS, Bessis D, Bouffandeau A, Moranne O, Jarrot PA, Bardin N, Terrier B, Burtey S, Puéchal X, Daniel L, Jourde-Chiche N
BMC Nephrol 2022 Feb 16;23(1):67. doi: 10.1186/s12882-022-02689-8. PMID: 35172758Free PMC Article

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