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Renal glomerular foam cells

MedGen UID:: 1717883
•Concept ID:: C5397608
•: Finding

HPO:	HP:0032583

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVRenal glomerular foam cells

Abnormal vascular morphology
- Abnormal blood vessel morphology
  - Abnormal systemic arterial morphology
    - Arteriosclerosis disorder
      - Atherosclerosis
        Foam cells
        Renal glomerular foam cells

Recent clinical studies

Etiology

Evaluation of C4d expression and staining patterns by immunohistochemistry in renal biopsy samples with focal segmental glomerulosclerosis and minimal change disease.

Abedi M, Nili F, Dehkhoda F, Abdollahi A, Salarvand S
Ann Diagn Pathol 2024 Jun;70:152281. Epub 2024 Feb 13 doi: 10.1016/j.anndiagpath.2024.152281. PMID: 38417352

APOL1 renal risk variants promote cholesterol accumulation in tissues and cultured macrophages from APOL1 transgenic mice.

Ryu JH, Ge M, Merscher S, Rosenberg AZ, Desante M, Roshanravan H, Okamoto K, Shin MK, Hoek M, Fornoni A, Kopp JB
PLoS One 2019;14(4):e0211559. Epub 2019 Apr 18 doi: 10.1371/journal.pone.0211559. PMID: 30998685 Free PMC Article

Topics in lipoprotein glomerulopathy: an overview.

Saito T, Matsunaga A, Ito K, Nakashima H
Clin Exp Nephrol 2014 Apr;18(2):214-7. Epub 2013 Oct 23 doi: 10.1007/s10157-013-0887-4. PMID: 24149835

Presence of foam cells in kidney interstitium is associated with progression of renal injury in patients with glomerular diseases.

Wu Y, Chen Y, Chen D, Zeng C, Li L, Liu Z
Nephron Clin Pract 2009;113(3):c155-61. Epub 2009 Aug 12 doi: 10.1159/000232596. PMID: 19672113

Morphological features of primary focal and segmental glomerulosclerosis.

Noël LH
Nephrol Dial Transplant 1999;14 Suppl 3:53-7. doi: 10.1093/ndt/14.suppl_3.53. PMID: 10382983

See all (14)

Diagnosis

Glomerular lipidosis as a feature of renal-limited macrophage activation syndrome in a transplanted kidney: a case report.

Sugisaki K, Uchida T, Iwama S, Okihara M, Akashi I, Kihara Y, Konno O, Kuroda M, Koike J, Iwamoto H, Oda T
BMC Nephrol 2023 Nov 7;24(1):329. doi: 10.1186/s12882-023-03380-2. PMID: 37936128 Free PMC Article

Histiocytic and Nonhistiocytic Glomerular Lesions: Foam Cells and Their Mimickers.

Kaur A, Sethi S
Am J Kidney Dis 2016 Feb;67(2):329-36. Epub 2015 Nov 19 doi: 10.1053/j.ajkd.2015.07.040. PMID: 26606995

Presence of foam cells in kidney interstitium is associated with progression of renal injury in patients with glomerular diseases.

Wu Y, Chen Y, Chen D, Zeng C, Li L, Liu Z
Nephron Clin Pract 2009;113(3):c155-61. Epub 2009 Aug 12 doi: 10.1159/000232596. PMID: 19672113

Renal pathology and ultrastructural findings in Alport's syndrome.

Noël LH
Ren Fail 2000 Nov;22(6):751-8. doi: 10.1081/jdi-100101960. PMID: 11104162

Focal glomerular sclerosis.

Mandal AK, Chrysant K, Nordquist JA, Kraikitpanitch S, Xoung DT, Lindeman RD
South Med J 1976 Aug;69(8):997-1001. doi: 10.1097/00007611-197608000-00010. PMID: 183292

See all (21)

Therapy

Glomerular lipidosis as a feature of renal-limited macrophage activation syndrome in a transplanted kidney: a case report.

Kidney Biopsy Features Most Predictive of Clinical Outcomes in the Spectrum of Minimal Change Disease and Focal Segmental Glomerulosclerosis.

Zee J, Liu Q, Smith AR, Hodgin JB, Rosenberg A, Gillespie BW, Holzman LB, Barisoni L, Mariani LH; Nephrotic Syndrome Study Network (NEPTUNE); NEPTUNE Members
J Am Soc Nephrol 2022 Jul;33(7):1411-1426. Epub 2022 May 17 doi: 10.1681/ASN.2021101396. PMID: 35581011 Free PMC Article

Topics in lipoprotein glomerulopathy: an overview.

Saito T, Matsunaga A, Ito K, Nakashima H
Clin Exp Nephrol 2014 Apr;18(2):214-7. Epub 2013 Oct 23 doi: 10.1007/s10157-013-0887-4. PMID: 24149835

Effects of HMG-CoA reductase inhibitors (statins) on progression of kidney disease.

Fried LF
Kidney Int 2008 Sep;74(5):571-6. Epub 2008 Jun 4 doi: 10.1038/ki.2008.231. PMID: 18528321

Calcium antagonists and cellular mechanisms of glomerulosclerosis and atherosclerosis.

Haller H
Am J Kidney Dis 1993 Jun;21(6 Suppl 3):26-31. PMID: 8503431

See all (11)

Prognosis

Evaluation of C4d expression and staining patterns by immunohistochemistry in renal biopsy samples with focal segmental glomerulosclerosis and minimal change disease.

Abedi M, Nili F, Dehkhoda F, Abdollahi A, Salarvand S
Ann Diagn Pathol 2024 Jun;70:152281. Epub 2024 Feb 13 doi: 10.1016/j.anndiagpath.2024.152281. PMID: 38417352

Kidney Biopsy Features Most Predictive of Clinical Outcomes in the Spectrum of Minimal Change Disease and Focal Segmental Glomerulosclerosis.

Evidence from the Oxford Classification cohort supports the clinical value of subclassification of focal segmental glomerulosclerosis in IgA nephropathy.

Bellur SS, Lepeytre F, Vorobyeva O, Troyanov S, Cook HT, Roberts IS; International IgA Nephropathy Working Group
Kidney Int 2017 Jan;91(1):235-243. Epub 2016 Dec 1 doi: 10.1016/j.kint.2016.09.029. PMID: 27914703

Primary focal segmental glomerular sclerosis in adults: prognostic value of histologic variants.

Schwartz MM, Korbet SM, Rydell J, Borok R, Genchi R
Am J Kidney Dis 1995 Jun;25(6):845-52. doi: 10.1016/0272-6386(95)90566-9. PMID: 7771480

Focal sclerosing glomerulonephropathy: a clinicopathologic study.

Velosa JA, Donadio JV Jr, Holley KE
Mayo Clin Proc 1975 Mar;50(3):121-33. PMID: 1090790

See all (14)