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Skin with High Degree of Cumulative Sun Damage

MedGen UID:
1718357
•Concept ID:
C5237349
•
Finding
Synonym: Skin with High Degree of Cumulative Sun Damage (CSD)

Definition

A finding indicating a high degree of cumulative sun damage in the skin as evidenced by severe solar keratosis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSkin with High Degree of Cumulative Sun Damage

Recent clinical studies

Etiology

Analyzing the relationship between the efficacy of first-line immune checkpoint inhibitors and cumulative sun damage in Japanese patients with advanced BRAF wild-type nonacral cutaneous melanoma: A retrospective real-world, multicenter study.
Inozume T, Namikawa K, Kato H, Yoshikawa S, Kiniwa Y, Yoshino K, Mizuhashi S, Ito T, Takenouchi T, Matsushita S, Fujisawa Y, Matsuzawa T, Sugihara S, Asai J, Kitagawa H, Maekawa T, Isei T, Yasuda M, Yamazaki N, Uhara H, Nakamura Y
J Dermatol Sci 2023 Apr;110(1):19-26. Epub 2023 Mar 31 doi: 10.1016/j.jdermsci.2023.03.008. PMID: 37045720
Histopathologic classification and prognostic factors of melanoma: a 2021 update.
Bobos M
Ital J Dermatol Venerol 2021 Jun;156(3):300-321. Epub 2021 May 13 doi: 10.23736/S2784-8671.21.06958-3. PMID: 33982546
The 2018 World Health Organization Classification of Cutaneous, Mucosal, and Uveal Melanoma: Detailed Analysis of 9 Distinct Subtypes Defined by Their Evolutionary Pathway.
Elder DE, Bastian BC, Cree IA, Massi D, Scolyer RA
Arch Pathol Lab Med 2020 Apr;144(4):500-522. Epub 2020 Feb 14 doi: 10.5858/arpa.2019-0561-RA. PMID: 32057276
BRAF mutations in cutaneous melanoma are independently associated with age, anatomic site of the primary tumor, and the degree of solar elastosis at the primary tumor site.
Bauer J, Büttner P, Murali R, Okamoto I, Kolaitis NA, Landi MT, Scolyer RA, Bastian BC
Pigment Cell Melanoma Res 2011 Apr;24(2):345-51. doi: 10.1111/j.1755-148X.2011.00837.x. PMID: 21324100Free PMC Article

Diagnosis

Histopathologic classification and prognostic factors of melanoma: a 2021 update.
Bobos M
Ital J Dermatol Venerol 2021 Jun;156(3):300-321. Epub 2021 May 13 doi: 10.23736/S2784-8671.21.06958-3. PMID: 33982546

Therapy

Analyzing the relationship between the efficacy of first-line immune checkpoint inhibitors and cumulative sun damage in Japanese patients with advanced BRAF wild-type nonacral cutaneous melanoma: A retrospective real-world, multicenter study.
Inozume T, Namikawa K, Kato H, Yoshikawa S, Kiniwa Y, Yoshino K, Mizuhashi S, Ito T, Takenouchi T, Matsushita S, Fujisawa Y, Matsuzawa T, Sugihara S, Asai J, Kitagawa H, Maekawa T, Isei T, Yasuda M, Yamazaki N, Uhara H, Nakamura Y
J Dermatol Sci 2023 Apr;110(1):19-26. Epub 2023 Mar 31 doi: 10.1016/j.jdermsci.2023.03.008. PMID: 37045720
Photoaging.
Sjerobabski Masnec I, Poduje S
Coll Antropol 2008 Oct;32 Suppl 2:177-80. PMID: 19140280

Prognosis

Analyzing the relationship between the efficacy of first-line immune checkpoint inhibitors and cumulative sun damage in Japanese patients with advanced BRAF wild-type nonacral cutaneous melanoma: A retrospective real-world, multicenter study.
Inozume T, Namikawa K, Kato H, Yoshikawa S, Kiniwa Y, Yoshino K, Mizuhashi S, Ito T, Takenouchi T, Matsushita S, Fujisawa Y, Matsuzawa T, Sugihara S, Asai J, Kitagawa H, Maekawa T, Isei T, Yasuda M, Yamazaki N, Uhara H, Nakamura Y
J Dermatol Sci 2023 Apr;110(1):19-26. Epub 2023 Mar 31 doi: 10.1016/j.jdermsci.2023.03.008. PMID: 37045720
Histopathologic classification and prognostic factors of melanoma: a 2021 update.
Bobos M
Ital J Dermatol Venerol 2021 Jun;156(3):300-321. Epub 2021 May 13 doi: 10.23736/S2784-8671.21.06958-3. PMID: 33982546

Clinical prediction guides

Analyzing the relationship between the efficacy of first-line immune checkpoint inhibitors and cumulative sun damage in Japanese patients with advanced BRAF wild-type nonacral cutaneous melanoma: A retrospective real-world, multicenter study.
Inozume T, Namikawa K, Kato H, Yoshikawa S, Kiniwa Y, Yoshino K, Mizuhashi S, Ito T, Takenouchi T, Matsushita S, Fujisawa Y, Matsuzawa T, Sugihara S, Asai J, Kitagawa H, Maekawa T, Isei T, Yasuda M, Yamazaki N, Uhara H, Nakamura Y
J Dermatol Sci 2023 Apr;110(1):19-26. Epub 2023 Mar 31 doi: 10.1016/j.jdermsci.2023.03.008. PMID: 37045720
Histopathologic classification and prognostic factors of melanoma: a 2021 update.
Bobos M
Ital J Dermatol Venerol 2021 Jun;156(3):300-321. Epub 2021 May 13 doi: 10.23736/S2784-8671.21.06958-3. PMID: 33982546

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