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Metastatic Malignant Neoplasm in the Regional Lymph Nodes

MedGen UID:
1738481
Concept ID:
C5421215
Neoplastic Process

Definition

The spread of a malignant neoplasm from its original site of growth to nearby lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Malignant Neoplasm in the Regional Lymph Nodes

Professional guidelines

PubMed

Ciabattoni A, Gregucci F, De Rose F, Falivene S, Fozza A, Daidone A, Morra A, Smaniotto D, Barbara R, Lozza L, Vidali C, Borghesi S, Palumbo I, Huscher A, Perrucci E, Baldissera A, Tolento G, Rovea P, Franco P, De Santis MC, Grazia AD, Marino L, Meduri B, Cucciarelli F, Aristei C, Bertoni F, Guenzi M, Leonardi MC, Livi L, Nardone L, De Felice F, Rosetto ME, Mazzuoli L, Anselmo P, Arcidiacono F, Barbarino R, Martinetti M, Pasinetti N, Desideri I, Marazzi F, Ivaldi G, Bonzano E, Cavallari M, Cerreta V, Fusco V, Sarno L, Bonanni A, Mangiacotti MG, Prisco A, Buonfrate G, Andrulli D, Fontana A, Bagnoli R, Marinelli L, Reverberi C, Scalabrino G, Corazzi F, Doino D, Di Genesio-Pagliuca M, Lazzari M, Mascioni F, Pace MP, Mazza M, Vitucci P, Spera A, Macchia G, Boccardi M, Evangelista G, Sola B, La Porta MR, Fiorentino A, Levra NG, Ippolito E, Silipigni S, Osti MF, Mignogna M, Alessandro M, Ursini LA, Nuzzo M, Meattini I, D'Ermo G
Tumori 2022 Jul;108(2_suppl):1-144. doi: 10.1177/03008916221088885. PMID: 36112842
Stratigos AJ, Garbe C, Dessinioti C, Lebbe C, Bataille V, Bastholt L, Dreno B, Concetta Fargnoli M, Forsea AM, Frenard C, Harwood CA, Hauschild A, Hoeller C, Kandolf-Sekulovic L, Kaufmann R, Kelleners-Smeets NWJ, Malvehy J, Del Marmol V, Middleton MR, Moreno-Ramirez D, Pellecani G, Peris K, Saiag P, van den Beuken-van Everdingen MHJ, Vieira R, Zalaudek I, Eggermont AMM, Grob JJ; European Dermatology Forum (EDF), the European Association of Dermato-Oncology (EADO) and the European Organization for Research and Treatment of Cancer (EORTC)
Eur J Cancer 2020 Mar;128:83-102. Epub 2020 Feb 26 doi: 10.1016/j.ejca.2020.01.008. PMID: 32113942
American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid Cancer, Cooper DS, Doherty GM, Haugen BR, Kloos RT, Lee SL, Mandel SJ, Mazzaferri EL, McIver B, Pacini F, Schlumberger M, Sherman SI, Steward DL, Tuttle RM
Thyroid 2009 Nov;19(11):1167-214. doi: 10.1089/thy.2009.0110. PMID: 19860577

Recent clinical studies

Etiology

Bauer A
Surg Clin North Am 2023 Feb;103(1):187-199. Epub 2022 Oct 17 doi: 10.1016/j.suc.2022.08.015. PMID: 36410350
Glaun MDE, Feng Z, Lango M
Oral Maxillofac Surg Clin North Am 2022 May;34(2):273-281. Epub 2022 Apr 7 doi: 10.1016/j.coms.2021.11.001. PMID: 35400571
Dessinioti C, Pitoulias M, Stratigos AJ
J Eur Acad Dermatol Venereol 2022 Jan;36(1):39-50. Epub 2021 Oct 11 doi: 10.1111/jdv.17709. PMID: 34592000
Bostanci MT, Yilmaz I
J Coll Physicians Surg Pak 2021 Jul;31(7):798-804. doi: 10.29271/jcpsp.2021.07.798. PMID: 34271779
Teichgraeber DC, Perez F, Guirguis MS, Kapoor MM, Whitman GJ
Ultrasound Q 2021 Jan 13;37(1):43-51. doi: 10.1097/RUQ.0000000000000546. PMID: 33464028

Diagnosis

Dessinioti C, Pitoulias M, Stratigos AJ
J Eur Acad Dermatol Venereol 2022 Jan;36(1):39-50. Epub 2021 Oct 11 doi: 10.1111/jdv.17709. PMID: 34592000
Prkačin I, Šitum M, Delaš Aždajić M, Puljiz Z
Acta Dermatovenerol Croat 2021 Jul;29(2):80-87. PMID: 34477073
Chen Y, Wen Z, Ma Y, Liu Y, Que Y, Yang X, Wu Y, Yu S
Jpn J Radiol 2021 Jul;39(7):642-651. Epub 2021 Mar 9 doi: 10.1007/s11604-021-01108-6. PMID: 33686499
Teichgraeber DC, Perez F, Guirguis MS, Kapoor MM, Whitman GJ
Ultrasound Q 2021 Jan 13;37(1):43-51. doi: 10.1097/RUQ.0000000000000546. PMID: 33464028
Ghimire P, Wu GY, Zhu L
World J Gastroenterol 2011 Feb 14;17(6):697-707. doi: 10.3748/wjg.v17.i6.697. PMID: 21390139Free PMC Article

Therapy

de Boniface J, Filtenborg Tvedskov T, Rydén L, Szulkin R, Reimer T, Kühn T, Kontos M, Gentilini OD, Olofsson Bagge R, Sund M, Lundstedt D, Appelgren M, Ahlgren J, Norenstedt S, Celebioglu F, Sackey H, Scheel Andersen I, Hoyer U, Nyman PF, Vikhe Patil E, Wieslander E, Dahl Nissen H, Alkner S, Andersson Y, Offersen BV, Bergkvist L, Frisell J, Christiansen P; SENOMAC Trialists’ Group; SENOMAC Trialists' Group
N Engl J Med 2024 Apr 4;390(13):1163-1175. doi: 10.1056/NEJMoa2313487. PMID: 38598571
Stratigos AJ, Garbe C, Dessinioti C, Lebbe C, Bataille V, Bastholt L, Dreno B, Concetta Fargnoli M, Forsea AM, Frenard C, Harwood CA, Hauschild A, Hoeller C, Kandolf-Sekulovic L, Kaufmann R, Kelleners-Smeets NWJ, Malvehy J, Del Marmol V, Middleton MR, Moreno-Ramirez D, Pellecani G, Peris K, Saiag P, van den Beuken-van Everdingen MHJ, Vieira R, Zalaudek I, Eggermont AMM, Grob JJ; European Dermatology Forum (EDF), the European Association of Dermato-Oncology (EADO) and the European Organization for Research and Treatment of Cancer (EORTC)
Eur J Cancer 2020 Mar;128:83-102. Epub 2020 Feb 26 doi: 10.1016/j.ejca.2020.01.008. PMID: 32113942
Giuliano AE, Ballman KV, McCall L, Beitsch PD, Brennan MB, Kelemen PR, Ollila DW, Hansen NM, Whitworth PW, Blumencranz PW, Leitch AM, Saha S, Hunt KK, Morrow M
JAMA 2017 Sep 12;318(10):918-926. doi: 10.1001/jama.2017.11470. PMID: 28898379Free PMC Article
Faries MB, Thompson JF, Cochran AJ, Andtbacka RH, Mozzillo N, Zager JS, Jahkola T, Bowles TL, Testori A, Beitsch PD, Hoekstra HJ, Moncrieff M, Ingvar C, Wouters MWJM, Sabel MS, Levine EA, Agnese D, Henderson M, Dummer R, Rossi CR, Neves RI, Trocha SD, Wright F, Byrd DR, Matter M, Hsueh E, MacKenzie-Ross A, Johnson DB, Terheyden P, Berger AC, Huston TL, Wayne JD, Smithers BM, Neuman HB, Schneebaum S, Gershenwald JE, Ariyan CE, Desai DC, Jacobs L, McMasters KM, Gesierich A, Hersey P, Bines SD, Kane JM, Barth RJ, McKinnon G, Farma JM, Schultz E, Vidal-Sicart S, Hoefer RA, Lewis JM, Scheri R, Kelley MC, Nieweg OE, Noyes RD, Hoon DSB, Wang HJ, Elashoff DA, Elashoff RM
N Engl J Med 2017 Jun 8;376(23):2211-2222. doi: 10.1056/NEJMoa1613210. PMID: 28591523Free PMC Article
American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid Cancer, Cooper DS, Doherty GM, Haugen BR, Kloos RT, Lee SL, Mandel SJ, Mazzaferri EL, McIver B, Pacini F, Schlumberger M, Sherman SI, Steward DL, Tuttle RM
Thyroid 2009 Nov;19(11):1167-214. doi: 10.1089/thy.2009.0110. PMID: 19860577

Prognosis

Teichgraeber DC, Perez F, Guirguis MS, Kapoor MM, Whitman GJ
Ultrasound Q 2021 Jan 13;37(1):43-51. doi: 10.1097/RUQ.0000000000000546. PMID: 33464028
Zhang J, Cheng X, Shen L, Wang X, Wang L, Sun X, Qu S
Front Endocrinol (Lausanne) 2020;11:90. Epub 2020 Feb 27 doi: 10.3389/fendo.2020.00090. PMID: 32174889Free PMC Article
Mansour J, Sagiv D, Alon E, Talmi Y
J Laryngol Otol 2018 Jan;132(1):8-13. Epub 2017 Nov 10 doi: 10.1017/S0022215117002250. PMID: 29122022
Chen LJ, Chung KP, Chang YJ, Chang YJ
Surg Oncol 2015 Sep;24(3):239-47. Epub 2015 May 19 doi: 10.1016/j.suronc.2015.05.001. PMID: 26055316
Karatzanis AD, Koudounarakis E, Papadakis I, Velegrakis G
Eur Arch Otorhinolaryngol 2012 Mar;269(3):731-7. Epub 2011 Oct 21 doi: 10.1007/s00405-011-1809-2. PMID: 22015738

Clinical prediction guides

Alameer E, Eagan A, Scholfield DW, Woods RSR, Tuttle RM, Wong RJ, Patel SG, Ganly I
JAMA Otolaryngol Head Neck Surg 2024 Jan 1;150(1):49-56. doi: 10.1001/jamaoto.2023.3668. PMID: 37971746Free PMC Article
Crimì F, Bao QR, Mari V, Zanon C, Cabrelle G, Spolverato G, Pucciarelli S, Quaia E
Tomography 2022 Apr 22;8(3):1196-1207. doi: 10.3390/tomography8030098. PMID: 35645384Free PMC Article
Prkačin I, Šitum M, Delaš Aždajić M, Puljiz Z
Acta Dermatovenerol Croat 2021 Jul;29(2):80-87. PMID: 34477073
Roy-Chowdhuri S, Krishnamurthy S
Semin Diagn Pathol 2015 Jul;32(4):250-7. Epub 2014 Dec 19 doi: 10.1053/j.semdp.2014.12.006. PMID: 25638437
Cowan NC, Crew JP
Curr Opin Urol 2010 Sep;20(5):409-13. doi: 10.1097/MOU.0b013e32833cbcb9. PMID: 20625298

Recent systematic reviews

Nguyen HCB, Mady LJ, Panara K, Andrianus S, Cooper K, Chen IH, Chalian AA, Brody RM
ORL J Otorhinolaryngol Relat Spec 2022;84(5):361-369. Epub 2022 Feb 3 doi: 10.1159/000521076. PMID: 35114675
Osto M, Parry N, Rehman R, Ahmed U, Mehregan D
Am J Dermatopathol 2021 Dec 1;43(12):851-866. doi: 10.1097/DAD.0000000000001991. PMID: 34797787
Christou N, Meyer J, Combescure C, Balaphas A, Robert-Yap J, Buchs NC, Ris F
World J Surg 2021 May;45(5):1537-1547. Epub 2021 Feb 4 doi: 10.1007/s00268-021-05956-1. PMID: 33543333Free PMC Article
Costa Svedman F, Spanopoulos D, Taylor A, Amelio J, Hansson J
J Eur Acad Dermatol Venereol 2017 Apr;31(4):603-615. Epub 2016 Oct 4 doi: 10.1111/jdv.13950. PMID: 27580240
Garbe C, Eigentler TK, Keilholz U, Hauschild A, Kirkwood JM
Oncologist 2011;16(1):5-24. Epub 2011 Jan 6 doi: 10.1634/theoncologist.2010-0190. PMID: 21212434Free PMC Article

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