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Digestive System Solitary Fibrous Tumor

MedGen UID:
1748301
•Concept ID:
C5419971
•
Neoplastic Process

Definition

A solitary fibrous tumor arising from an anatomic site in the digestive system, including the esophagus, gallbladder, liver, pancreas, small bowel mesentery, and the serosal surfaces of the stomach and colon. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDigestive System Solitary Fibrous Tumor

Professional guidelines

PubMed

Rare benign liver tumors that require differentiation from hepatocellular carcinoma: focus on diagnosis and treatment.
Luo L, Wang T, Cheng M, Ge X, Song S, Zhu G, Xiao Y, Deng W, Xie J, Shan R
J Cancer Res Clin Oncol 2023 Jul;149(7):2843-2854. Epub 2022 Jul 5 doi: 10.1007/s00432-022-04169-w. PMID: 35789428
PDGFR expression in differential diagnosis between KIT-negative gastrointestinal stromal tumours and other primary soft-tissue tumours of the gastrointestinal tract.
Rossi G, Valli R, Bertolini F, Marchioni A, Cavazza A, Mucciarini C, Migaldi M, Federico M, Trentini GP, Sgambato A
Histopathology 2005 May;46(5):522-31. doi: 10.1111/j.1365-2559.2005.02128.x. PMID: 15842634

Recent clinical studies

Etiology

Solitary fibrous tumor of head and neck region; A clinicopathological study of 67 cases emphasizing the diversity of histological features and utility of various risk stratification models.
Tariq MU, Asghari T, Armstrong SM, Ahmed A, Fritchie K, Din NU
Pathol Res Pract 2023 Sep;249:154777. Epub 2023 Aug 22 doi: 10.1016/j.prp.2023.154777. PMID: 37639955
Solitary fibrous tumor of parotid gland: a case report and short review of literature.
Goker F, Mazzucato C, Maggioni M, Baj A, Giannì AB, Beltramini G, Russillo A, Buccellato FRP, Rossi DS, Mortellaro C, Del Fabbro M
Eur Rev Med Pharmacol Sci 2022 Dec;26(3 Suppl):45-50. doi: 10.26355/eurrev_202212_30794. PMID: 36591884
Clinicopathologic characterization and assessment of prognostic factors for intraabdominal solitary fibrous tumors involving the gastrointestinal tract and liver.
Liu X, Beltejar MJ, Liao X
Virchows Arch 2022 Nov;481(5):703-712. Epub 2022 Aug 17 doi: 10.1007/s00428-022-03396-3. PMID: 35978144
Mesenchymal Neoplasms of Salivary Glands: A Clinicopathologic Study of 68 Cases.
Velez Torres JM, Duarte EM, Diaz-Perez JA, Leibowitz J, Weed DT, Thomas G, Sargi Z, Civantos FJ, Arnold DJ, Gomez-Fernandez C, Montgomery EA, Rosenberg AE
Head Neck Pathol 2022 Jun;16(2):353-365. Epub 2021 Jul 12 doi: 10.1007/s12105-021-01360-2. PMID: 34251596Free PMC Article
Solitary fibrous tumor of the liver: report of two cases and review of the literature.
Debs T, Kassir R, Amor IB, Martini F, Iannelli A, Gugenheim J
Int J Surg 2014 Dec;12(12):1291-4. Epub 2014 Nov 4 doi: 10.1016/j.ijsu.2014.10.037. PMID: 25448647

Diagnosis

Solitary fibrous tumor of head and neck region; A clinicopathological study of 67 cases emphasizing the diversity of histological features and utility of various risk stratification models.
Tariq MU, Asghari T, Armstrong SM, Ahmed A, Fritchie K, Din NU
Pathol Res Pract 2023 Sep;249:154777. Epub 2023 Aug 22 doi: 10.1016/j.prp.2023.154777. PMID: 37639955
Solitary fibrous tumor of parotid gland: a case report and short review of literature.
Goker F, Mazzucato C, Maggioni M, Baj A, Giannì AB, Beltramini G, Russillo A, Buccellato FRP, Rossi DS, Mortellaro C, Del Fabbro M
Eur Rev Med Pharmacol Sci 2022 Dec;26(3 Suppl):45-50. doi: 10.26355/eurrev_202212_30794. PMID: 36591884
Mesenchymal Tumors Involving the Pancreas: A Clinicopathologic Analysis and Review of the Literature.
Askan G, Basturk O
Turk Patoloji Derg 2022;38(1):46-53. doi: 10.5146/tjpath.2022.01567. PMID: 35001360Free PMC Article
Solitary fibrous tumour of the oral cavity: An update.
Nunes FB, Sant'Ana MSP, Silva AMB, Agostini M, Silva Canedo NH, de Andrade BAB, Romañach MJ, Corrêa DL, Tomasi RA, Radhakrishnan R, Gomez RS, de Sousa SF, Brennan PA, Fonseca FP
J Oral Pathol Med 2020 Jan;49(1):14-20. Epub 2019 Sep 15 doi: 10.1111/jop.12953. PMID: 31424136
Diagnosis of solitary fibrous tumor in the submandibular gland: Case report and literature review.
Jiang L, Hu C, Chen L, Chen L
J Clin Ultrasound 2019 Oct;47(8):486-489. Epub 2019 Jul 31 doi: 10.1002/jcu.22760. PMID: 31364769

Therapy

Atypical/malignant solitary fibrous tumor of the pancreas with spleen vein invasion: Case report and literature review.
Li J, Li J, Xiong Y, Xu T, Xu J, Li Q, Yang G
Medicine (Baltimore) 2020 Apr;99(17):e19783. doi: 10.1097/MD.0000000000019783. PMID: 32332621Free PMC Article
Solitary fibrous tumor of small bowel mesentery with postoperative bowel obstruction: a case report and review of literature.
Zhang GJ, Li RT, Zhou Y, Huang F, Zhao ZC, Li WD, Fu WH
Int J Clin Exp Pathol 2015;8(9):11691-7. Epub 2015 Sep 1 PMID: 26617912Free PMC Article
Gastrointestinal stromal tumors (GISTs) on prostate needle biopsy: A clinicopathologic study of 8 cases.
Herawi M, Montgomery EA, Epstein JI
Am J Surg Pathol 2006 Nov;30(11):1389-95. doi: 10.1097/01.pas.0000209847.59670.c8. PMID: 17063078
Hepatic tumors induced by sex steroids.
Mays ET, Christopherson W
Semin Liver Dis 1984 May;4(2):147-57. doi: 10.1055/s-2008-1040654. PMID: 6087460

Prognosis

Solitary fibrous tumor of head and neck region; A clinicopathological study of 67 cases emphasizing the diversity of histological features and utility of various risk stratification models.
Tariq MU, Asghari T, Armstrong SM, Ahmed A, Fritchie K, Din NU
Pathol Res Pract 2023 Sep;249:154777. Epub 2023 Aug 22 doi: 10.1016/j.prp.2023.154777. PMID: 37639955
Clinicopathologic characterization and assessment of prognostic factors for intraabdominal solitary fibrous tumors involving the gastrointestinal tract and liver.
Liu X, Beltejar MJ, Liao X
Virchows Arch 2022 Nov;481(5):703-712. Epub 2022 Aug 17 doi: 10.1007/s00428-022-03396-3. PMID: 35978144
Solitary fibrous tumor of the mesentery: a case report and review of the literature.
Liu JN, Liu Z, Ji PY, Zhang H, Guo SL
J Int Med Res 2020 Oct;48(10):300060520950111. doi: 10.1177/0300060520950111. PMID: 33050750Free PMC Article
Skull base metastases from a malignant solitary fibrous tumor of the liver. A case report and literature review.
Peng L, Liu Y, Ai Y, Liu Z, He Y, Liu Q
Diagn Pathol 2011 Dec 22;6:127. doi: 10.1186/1746-1596-6-127. PMID: 22192457Free PMC Article
Primary hepatic malignant fibrous histiocytoma: clinicopathologic characteristics and prognostic value of ezrin expression.
Li YR, Akbari E, Tretiakova MS, Hart J, Akbari M, Urbanski SJ, Gao ZH
Am J Surg Pathol 2008 Aug;32(8):1144-58. doi: 10.1097/PAS.0b013e3181659791. PMID: 18545143

Clinical prediction guides

Solitary fibrous tumor of head and neck region; A clinicopathological study of 67 cases emphasizing the diversity of histological features and utility of various risk stratification models.
Tariq MU, Asghari T, Armstrong SM, Ahmed A, Fritchie K, Din NU
Pathol Res Pract 2023 Sep;249:154777. Epub 2023 Aug 22 doi: 10.1016/j.prp.2023.154777. PMID: 37639955
Clinicopathologic characterization and assessment of prognostic factors for intraabdominal solitary fibrous tumors involving the gastrointestinal tract and liver.
Liu X, Beltejar MJ, Liao X
Virchows Arch 2022 Nov;481(5):703-712. Epub 2022 Aug 17 doi: 10.1007/s00428-022-03396-3. PMID: 35978144
Clinicopathologic and immunohistochemical features of five new cases of solitary fibrous tumor of the oral cavity.
Carlos R, de Andrade BA, Canedo NH, Abrahão AC, Agostini M, de Almeida OP, Romañach MJ
Oral Surg Oral Med Oral Pathol Oral Radiol 2016 Apr;121(4):390-5. Epub 2015 Nov 14 doi: 10.1016/j.oooo.2015.11.001. PMID: 26852825
Primary hepatic malignant fibrous histiocytoma: clinicopathologic characteristics and prognostic value of ezrin expression.
Li YR, Akbari E, Tretiakova MS, Hart J, Akbari M, Urbanski SJ, Gao ZH
Am J Surg Pathol 2008 Aug;32(8):1144-58. doi: 10.1097/PAS.0b013e3181659791. PMID: 18545143
Hepatic tumors induced by sex steroids.
Mays ET, Christopherson W
Semin Liver Dis 1984 May;4(2):147-57. doi: 10.1055/s-2008-1040654. PMID: 6087460

Recent systematic reviews

Primary hepatic malignant fibrous histiocytoma: clinicopathologic characteristics and prognostic value of ezrin expression.
Li YR, Akbari E, Tretiakova MS, Hart J, Akbari M, Urbanski SJ, Gao ZH
Am J Surg Pathol 2008 Aug;32(8):1144-58. doi: 10.1097/PAS.0b013e3181659791. PMID: 18545143

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