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Bulbous tooth

MedGen UID:
1785466
•Concept ID:
C5539809
•
Anatomical Abnormality
HPO: HP:0033780

Definition

A tooth crown with a marked cervical area constriction. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBulbous tooth

Professional guidelines

PubMed

Phenotype-genotype correlation in potential female carriers of X-linked developmental cataract (Nance-Horan syndrome).
Khan AO, Aldahmesh MA, Mohamed JY, Alkuraya FS
Ophthalmic Genet 2012 Jun;33(2):89-95. Epub 2012 Jan 9 doi: 10.3109/13816810.2011.634881. PMID: 22229851
Clinical application of povidone-iodine oral antiseptic 1% (Betadine mouthwash) and povidone-iodine skin antiseptic 10% (Betadine solution) for the management of odontogenic and deep fascial space infection.
Valderrama LS
Dermatology 2006;212 Suppl 1:112-4. doi: 10.1159/000089209. PMID: 16490987

Recent clinical studies

Etiology

Chapter 4: Development Defects of Enamel and Dentine and Coronal Caries.
Manton DJ, Vieira AR
Monogr Oral Sci 2023;31:37-49. Epub 2023 Jun 26 doi: 10.1159/000530556. PMID: 37364549
Correcting Occlusal Dysfunction While Addressing Patient's Esthetic Concerns.
Graas J
Compend Contin Educ Dent 2022 Sep;43(8):514-518. PMID: 36170632
Dental abnormalities in individuals with pathogenic germline variation in DICER1.
Choi S, Lee JS, Bassim CW, Kushner H, Carr AG, Gardner PJ, Harney LA, Schultz KAP, Stewart DR
Am J Med Genet A 2019 Sep;179(9):1820-1825. Epub 2019 Jul 16 doi: 10.1002/ajmg.a.61292. PMID: 31313479Free PMC Article
Predictive factors of difficulty in lower third molar extraction: A prospective cohort study.
Alvira-González J, Figueiredo R, Valmaseda-Castellón E, Quesada-Gómez C, Gay-Escoda C
Med Oral Patol Oral Cir Bucal 2017 Jan 1;22(1):e108-e114. doi: 10.4317/medoral.21348. PMID: 27918736Free PMC Article
Hereditary dentine disorders: dentinogenesis imperfecta and dentine dysplasia.
Barron MJ, McDonnell ST, Mackie I, Dixon MJ
Orphanet J Rare Dis 2008 Nov 20;3:31. doi: 10.1186/1750-1172-3-31. PMID: 19021896Free PMC Article

Diagnosis

Chapter 4: Development Defects of Enamel and Dentine and Coronal Caries.
Manton DJ, Vieira AR
Monogr Oral Sci 2023;31:37-49. Epub 2023 Jun 26 doi: 10.1159/000530556. PMID: 37364549
Correcting Occlusal Dysfunction While Addressing Patient's Esthetic Concerns.
Graas J
Compend Contin Educ Dent 2022 Sep;43(8):514-518. PMID: 36170632
ZMYND11-related syndromic intellectual disability: 16 patients delineating and expanding the phenotypic spectrum.
Yates TM, Drucker M, Barnicoat A, Low K, Gerkes EH, Fry AE, Parker MJ, O'Driscoll M, Charles P, Cox H, Marey I, Keren B, Rinne T, McEntagart M, Ramachandran V, Drury S, Vansenne F, Sival DA, Herkert JC, Callewaert B, Tan WH, Balasubramanian M
Hum Mutat 2020 May;41(5):1042-1050. Epub 2020 Mar 5 doi: 10.1002/humu.24001. PMID: 32097528
Hereditary dentine disorders: dentinogenesis imperfecta and dentine dysplasia.
Barron MJ, McDonnell ST, Mackie I, Dixon MJ
Orphanet J Rare Dis 2008 Nov 20;3:31. doi: 10.1186/1750-1172-3-31. PMID: 19021896Free PMC Article
Otodental syndrome.
Bloch-Zupan A, Goodman JR
Orphanet J Rare Dis 2006 Mar 21;1:5. doi: 10.1186/1750-1172-1-5. PMID: 16722606Free PMC Article

Therapy

Clinical delineation of the PACS1-related syndrome--Report on 19 patients.
Schuurs-Hoeijmakers JH, Landsverk ML, Foulds N, Kukolich MK, Gavrilova RH, Greville-Heygate S, Hanson-Kahn A, Bernstein JA, Glass J, Chitayat D, Burrow TA, Husami A, Collins K, Wusik K, van der Aa N, Kooy F, Brown KT, Gadzicki D, Kini U, Alvarez S, Fernández-Jaén A, McGehee F, Selby K, Tarailo-Graovac M, Van Allen M, van Karnebeek CD, Stavropoulos DJ, Marshall CR, Merico D, Gregor A, Zweier C, Hopkin RJ, Chu YW, Chung BH, de Vries BB, Devriendt K, Hurles ME, Brunner HG; DDD study
Am J Med Genet A 2016 Mar;170(3):670-5. Epub 2016 Feb 3 doi: 10.1002/ajmg.a.37476. PMID: 26842493
Dental abnormalities and preventive oral care in Schimke immuno-osseous dysplasia.
Gendronneau M, Kérourédan O, Taque S, Sixou JL, Bonnaure-Mallet M
Eur Arch Paediatr Dent 2014 Jun;15(3):217-21. Epub 2013 Dec 11 doi: 10.1007/s40368-013-0099-3. PMID: 24327104Free PMC Article
Clinical application of povidone-iodine oral antiseptic 1% (Betadine mouthwash) and povidone-iodine skin antiseptic 10% (Betadine solution) for the management of odontogenic and deep fascial space infection.
Valderrama LS
Dermatology 2006;212 Suppl 1:112-4. doi: 10.1159/000089209. PMID: 16490987
Treating patients with drug-induced gingival overgrowth.
Thompson AL, Herman WW, Konzelman J, Collins MA
J Dent Hyg 2004 Fall;78(4):12. Epub 2004 Oct 1 PMID: 16197752
Abnormalities of GH secretion in a young girl with Floating-Harbor syndrome.
Cannavò S, Bartolone L, Lapa D, Venturino M, Almoto B, Violi A, Trimarchi F
J Endocrinol Invest 2002 Jan;25(1):58-64. doi: 10.1007/BF03343962. PMID: 11883867

Prognosis

Cementoblastoma Mimicking Pathology of Endodontic Origin: A Case Report.
Sharma S, Blicher B, Pryles RL, Kerr DA, Addante R
Compend Contin Educ Dent 2024 Apr;45(4):210-212. PMID: 38622081
ZMYND11-related syndromic intellectual disability: 16 patients delineating and expanding the phenotypic spectrum.
Yates TM, Drucker M, Barnicoat A, Low K, Gerkes EH, Fry AE, Parker MJ, O'Driscoll M, Charles P, Cox H, Marey I, Keren B, Rinne T, McEntagart M, Ramachandran V, Drury S, Vansenne F, Sival DA, Herkert JC, Callewaert B, Tan WH, Balasubramanian M
Hum Mutat 2020 May;41(5):1042-1050. Epub 2020 Mar 5 doi: 10.1002/humu.24001. PMID: 32097528
Predictive factors of difficulty in lower third molar extraction: A prospective cohort study.
Alvira-González J, Figueiredo R, Valmaseda-Castellón E, Quesada-Gómez C, Gay-Escoda C
Med Oral Patol Oral Cir Bucal 2017 Jan 1;22(1):e108-e114. doi: 10.4317/medoral.21348. PMID: 27918736Free PMC Article
Dental abnormalities and preventive oral care in Schimke immuno-osseous dysplasia.
Gendronneau M, Kérourédan O, Taque S, Sixou JL, Bonnaure-Mallet M
Eur Arch Paediatr Dent 2014 Jun;15(3):217-21. Epub 2013 Dec 11 doi: 10.1007/s40368-013-0099-3. PMID: 24327104Free PMC Article
The myth of instant orthodontics: an ethical quandary.
Jacobson N, Frank CA
J Am Dent Assoc 2008 Apr;139(4):424-34. doi: 10.14219/jada.archive.2008.0185. PMID: 18385026

Clinical prediction guides

ZMYND11-related syndromic intellectual disability: 16 patients delineating and expanding the phenotypic spectrum.
Yates TM, Drucker M, Barnicoat A, Low K, Gerkes EH, Fry AE, Parker MJ, O'Driscoll M, Charles P, Cox H, Marey I, Keren B, Rinne T, McEntagart M, Ramachandran V, Drury S, Vansenne F, Sival DA, Herkert JC, Callewaert B, Tan WH, Balasubramanian M
Hum Mutat 2020 May;41(5):1042-1050. Epub 2020 Mar 5 doi: 10.1002/humu.24001. PMID: 32097528
Dental abnormalities in individuals with pathogenic germline variation in DICER1.
Choi S, Lee JS, Bassim CW, Kushner H, Carr AG, Gardner PJ, Harney LA, Schultz KAP, Stewart DR
Am J Med Genet A 2019 Sep;179(9):1820-1825. Epub 2019 Jul 16 doi: 10.1002/ajmg.a.61292. PMID: 31313479Free PMC Article
Predictive factors of difficulty in lower third molar extraction: A prospective cohort study.
Alvira-González J, Figueiredo R, Valmaseda-Castellón E, Quesada-Gómez C, Gay-Escoda C
Med Oral Patol Oral Cir Bucal 2017 Jan 1;22(1):e108-e114. doi: 10.4317/medoral.21348. PMID: 27918736Free PMC Article
The myth of instant orthodontics: an ethical quandary.
Jacobson N, Frank CA
J Am Dent Assoc 2008 Apr;139(4):424-34. doi: 10.14219/jada.archive.2008.0185. PMID: 18385026
Clinical application of povidone-iodine oral antiseptic 1% (Betadine mouthwash) and povidone-iodine skin antiseptic 10% (Betadine solution) for the management of odontogenic and deep fascial space infection.
Valderrama LS
Dermatology 2006;212 Suppl 1:112-4. doi: 10.1159/000089209. PMID: 16490987

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