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Cylindroma

MedGen UID:
1786768
•Concept ID:
C5441545
•
Neoplastic Process
Synonyms: Cylindroma of skin; Cylindroma of Skin; Cylindroma of the Skin; Dermal cylindroma; Dermal Cylindroma
SNOMED CT: Cylindroma of skin (447147008); Dermal cylindroma (447147008)
 
HPO: HP:0031024

Definition

A benign skin adnexal tumor of eccrine differentiation. [from HPO]

Professional guidelines

PubMed

Treatment outcomes of single-fraction stereotactic radiosurgery for adenoid cystic carcinoma: a case series of 55 patients.
Hong S, Garces YI, Price KA, Shinya Y, Parney IF, Link MJ, Pollock BE
J Neurooncol 2024 Jan;166(2):369-376. Epub 2024 Jan 5 doi: 10.1007/s11060-024-04561-1. PMID: 38180687
Breast lesions of uncertain malignant nature and limited metastatic potential: proposals to improve their recognition and clinical management.
Rakha EA, Badve S, Eusebi V, Reis-Filho JS, Fox SB, Dabbs DJ, Decker T, Hodi Z, Ichihara S, Lee AH, Palacios J, Richardson AL, Vincent-Salomon A, Schmitt FC, Tan PH, Tse GM, Ellis IO
Histopathology 2016 Jan;68(1):45-56. doi: 10.1111/his.12861. PMID: 26348644Free PMC Article
The treatment of adenoid cystic carcinoma (cylindroma) of the respiratory tract by surgery and radiation therapy.
VIETA JO, MAIER HC
Dis Chest 1957 May;31(5):493-511. doi: 10.1378/chest.31.5.493. PMID: 13414594

Recent clinical studies

Etiology

CD56 expression in basaloid anal squamous cell carcinoma - A potential diagnostic pitfall.
Madahian S, Judelson R, Zhu X, Meng X, Dresser K, Hutchinson L, Bledsoe JR
Ann Diagn Pathol 2021 Aug;53:151758. Epub 2021 May 8 doi: 10.1016/j.anndiagpath.2021.151758. PMID: 33989959
Glioma-Associated Oncogene-1 Expression in Basal Cell Carcinoma and Its Histologic Mimics.
Gradecki SE, Eid MV, Pramoonjago P, Wick MR
Am J Dermatopathol 2021 Sep 1;43(9):637-641. doi: 10.1097/DAD.0000000000001859. PMID: 33264133
CYLD mutation characterizes a subset of HPV-positive head and neck squamous cell carcinomas with distinctive genomics and frequent cylindroma-like histologic features.
Williams EA, Montesion M, Alexander BM, Ramkissoon SH, Elvin JA, Ross JS, Williams KJ, Glomski K, Bledsoe JR, Tse JY, Mochel MC
Mod Pathol 2021 Feb;34(2):358-370. Epub 2020 Sep 5 doi: 10.1038/s41379-020-00672-y. PMID: 32892208Free PMC Article
Magnifying glass on spiradenoma and cylindroma histogenesis and tumorigenesis using systematic transcriptome analysis.
Bell AH, Prieto VG, Ferrarotto R, Goepfert RP, Myers JN, Weber R, Bell D
Ann Diagn Pathol 2019 Aug;41:14-23. Epub 2019 May 5 doi: 10.1016/j.anndiagpath.2019.04.015. PMID: 31128548
MYB, CD117 and SOX-10 expression in cutaneous adnexal tumors.
Evangelista MT, North JP
J Cutan Pathol 2017 May;44(5):444-450. Epub 2017 Feb 14 doi: 10.1111/cup.12904. PMID: 28098399

Diagnosis

Magnifying glass on spiradenoma and cylindroma histogenesis and tumorigenesis using systematic transcriptome analysis.
Bell AH, Prieto VG, Ferrarotto R, Goepfert RP, Myers JN, Weber R, Bell D
Ann Diagn Pathol 2019 Aug;41:14-23. Epub 2019 May 5 doi: 10.1016/j.anndiagpath.2019.04.015. PMID: 31128548
Cylindroma: an update.
Jordão C, de Magalhães TC, Cuzzi T, Ramos-e-Silva M
Int J Dermatol 2015 Mar;54(3):275-8. Epub 2014 Dec 16 doi: 10.1111/ijd.12600. PMID: 25515269
Brooke-Spiegler syndrome.
Kim C, Kovich OI, Dosik J
Dermatol Online J 2007 Jan 27;13(1):10. PMID: 17511943
Bronchial adenomas.
Burcharth F, Axelsson C
Thorax 1972 Jul;27(4):442-9. doi: 10.1136/thx.27.4.442. PMID: 4342435Free PMC Article
OBSCURE OTALGIA.
HORA JF, BROWN AK Jr
Laryngoscope 1964 Jan;74:122-33. doi: 10.1002/lary.5540740115. PMID: 14119585

Therapy

Brooke-Spiegler syndrome: report of two cases not associated with a mutation in the CYLD and PTCH tumor-suppressor genes.
Ponti G, Nasti S, Losi L, Pastorino L, Pollio A, Benassi L, Giudice S, Bertazzoni G, Veratti E, Azzoni P, Bianchi Scarrà G, Seidenari S
J Cutan Pathol 2012 Mar;39(3):366-71. Epub 2011 Nov 12 doi: 10.1111/j.1600-0560.2011.01813.x. PMID: 22077640
Expression of p53 and TP53 mutational analysis in malignant neoplasms arising in preexisting spiradenoma, cylindroma, and spiradenocylindroma, sporadic or associated with Brooke-Spiegler syndrome.
Kazakov DV, Grossmann P, Spagnolo DV, Vanecek T, Vazmitel M, Kacerovska D, Zelger B, Calonje E, Michal M
Am J Dermatopathol 2010 May;32(3):215-221. doi: 10.1097/DAD.0b013e3181b9678c. PMID: 20075707
Brooke-Spiegler syndrome.
Layegh P, Sharifi-Sistani N, Abadian M, Moghiman T
Indian J Dermatol Venereol Leprol 2008 Nov-Dec;74(6):632-4. doi: 10.4103/0378-6323.45109. PMID: 19171990
Response of epidermoid and non-epidermoid cancers of the head and neck to fast neutron irradiation: the Fermilab experience.
Kurup PD, Mansell J, TenHaken RK, Hendrickson FR, Cohen L, Awschalom M, Rosenberg I
Int J Radiat Oncol Biol Phys 1984 Apr;10(4):473-9. doi: 10.1016/0360-3016(84)90026-9. PMID: 6327576
Cylindroma.
Evans JC, Efskind J, Roberts TW
Am J Roentgenol Radium Ther Nucl Med 1966 Jan;96(1):191-6. doi: 10.2214/ajr.96.1.191. PMID: 4285059

Prognosis

CD56 expression in basaloid anal squamous cell carcinoma - A potential diagnostic pitfall.
Madahian S, Judelson R, Zhu X, Meng X, Dresser K, Hutchinson L, Bledsoe JR
Ann Diagn Pathol 2021 Aug;53:151758. Epub 2021 May 8 doi: 10.1016/j.anndiagpath.2021.151758. PMID: 33989959
Glioma-Associated Oncogene-1 Expression in Basal Cell Carcinoma and Its Histologic Mimics.
Gradecki SE, Eid MV, Pramoonjago P, Wick MR
Am J Dermatopathol 2021 Sep 1;43(9):637-641. doi: 10.1097/DAD.0000000000001859. PMID: 33264133
CYLD mutation characterizes a subset of HPV-positive head and neck squamous cell carcinomas with distinctive genomics and frequent cylindroma-like histologic features.
Williams EA, Montesion M, Alexander BM, Ramkissoon SH, Elvin JA, Ross JS, Williams KJ, Glomski K, Bledsoe JR, Tse JY, Mochel MC
Mod Pathol 2021 Feb;34(2):358-370. Epub 2020 Sep 5 doi: 10.1038/s41379-020-00672-y. PMID: 32892208Free PMC Article
Radiotherapy for Tracheal-Bronchial Cystic Adenoid Carcinomas.
Levy A, Omeiri A, Fadel E, Le Péchoux C
Clin Oncol (R Coll Radiol) 2018 Jan;30(1):39-46. Epub 2017 Nov 6 doi: 10.1016/j.clon.2017.10.012. PMID: 29122457
'Ceruminoma'--a defunct diagnosis.
Mills RG, Douglas-Jones T, Williams RG
J Laryngol Otol 1995 Mar;109(3):180-8. PMID: 7745330

Clinical prediction guides

Magnifying glass on spiradenoma and cylindroma histogenesis and tumorigenesis using systematic transcriptome analysis.
Bell AH, Prieto VG, Ferrarotto R, Goepfert RP, Myers JN, Weber R, Bell D
Ann Diagn Pathol 2019 Aug;41:14-23. Epub 2019 May 5 doi: 10.1016/j.anndiagpath.2019.04.015. PMID: 31128548
The role of DOG1 immunohistochemistry in dermatopathology.
Goto K
J Cutan Pathol 2016 Nov;43(11):974-983. Epub 2016 Sep 5 doi: 10.1111/cup.12787. PMID: 27506854
Breast lesions of uncertain malignant nature and limited metastatic potential: proposals to improve their recognition and clinical management.
Rakha EA, Badve S, Eusebi V, Reis-Filho JS, Fox SB, Dabbs DJ, Decker T, Hodi Z, Ichihara S, Lee AH, Palacios J, Richardson AL, Vincent-Salomon A, Schmitt FC, Tan PH, Tse GM, Ellis IO
Histopathology 2016 Jan;68(1):45-56. doi: 10.1111/his.12861. PMID: 26348644Free PMC Article
Immunophenotypic aspects of cylindroma and nodular hidradenoma.
Canedo T, de Almeida MP, Cuzzi T, Ramos-e-Silva M
J Eur Acad Dermatol Venereol 2010 Feb;24(2):178-85. Epub 2009 Sep 30 doi: 10.1111/j.1468-3083.2009.03398.x. PMID: 19796089
Cutaneous cylindroma with malignant transformation.
Gerretsen AL, van der Putte SC, Deenstra W, van Vloten WA
Cancer 1993 Sep 1;72(5):1618-23. doi: 10.1002/1097-0142(19930901)72:5<1618::aid-cncr2820720521>3.0.co;2-5. PMID: 7688655

Recent systematic reviews

Laryngeal Adenoid Cystic Carcinoma: A Systematic Review.
Marchiano E, Chin OY, Fang CH, Park RC, Baredes S, Eloy JA
Otolaryngol Head Neck Surg 2016 Mar;154(3):433-9. Epub 2015 Dec 23 doi: 10.1177/0194599815621884. PMID: 26701176
Cylindroma of head and neck: review of the literature and report of two rare cases.
Singh DD, Naujoks C, Depprich R, Schulte KW, Jankowiak F, Kübler NR, Handschel J
J Craniomaxillofac Surg 2013 Sep;41(6):516-21. Epub 2012 Dec 21 doi: 10.1016/j.jcms.2012.11.016. PMID: 23260808

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