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Refractory Clear Cell Sarcoma of Soft Tissue

MedGen UID:
1793207
•Concept ID:
C5556766
•
Neoplastic Process

Definition

Clear cell sarcoma of soft tissue that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Clear Cell Sarcoma of Soft Tissue

Professional guidelines

PubMed

Autologous Stem Cell Transplantation for Children With Renal Tumors, and Adults With Wilms Tumor: Retrospective Analysis of the Japanese Transplant Registry Unified Management Program.
Kobayashi R, Inoue M, Takahashi Y, Kikuta A, Ogawa A, Koga Y, Koh K, Hashii Y, Hara J, Kato K, Tabuchi K, Matsumoto K
J Pediatr Hematol Oncol 2020 May;42(4):251-255. doi: 10.1097/MPH.0000000000001779. PMID: 32134841

Recent clinical studies

Etiology

Cost-effectiveness of gilteritinib for relapsed/refractory FLT3(mut+) acute myeloid leukemia.
Pandya BJ, Qi CZ, Garnham A, Yang H, Shah MV, Zeidan AM
J Manag Care Spec Pharm 2021 Oct;27(10):1469-1481. doi: 10.18553/jmcp.2021.27.10.1469. PMID: 34595955Free PMC Article
Progress Update in Pediatric Renal Tumors.
Jain J, Sutton KS, Hong AL
Curr Oncol Rep 2021 Feb 16;23(3):33. doi: 10.1007/s11912-021-01016-y. PMID: 33591402
Adult Langerhans cell histiocytosis presenting with multisystem involvement and sarcomatoid features: a case report.
Aguirre LE, Schwartz I, Chapman J, Larsen MF, Alencar A
J Med Case Rep 2020 Sep 27;14(1):169. doi: 10.1186/s13256-020-02460-3. PMID: 32979930Free PMC Article
Autologous Stem Cell Transplantation for Children With Renal Tumors, and Adults With Wilms Tumor: Retrospective Analysis of the Japanese Transplant Registry Unified Management Program.
Kobayashi R, Inoue M, Takahashi Y, Kikuta A, Ogawa A, Koga Y, Koh K, Hashii Y, Hara J, Kato K, Tabuchi K, Matsumoto K
J Pediatr Hematol Oncol 2020 May;42(4):251-255. doi: 10.1097/MPH.0000000000001779. PMID: 32134841
A phase 1 study of cabozantinib in children and adolescents with recurrent or refractory solid tumors, including CNS tumors: Trial ADVL1211, a report from the Children's Oncology Group.
Chuk MK, Widemann BC, Minard CG, Liu X, Kim A, Bernhardt MB, Kudgus RA, Reid JM, Voss SD, Blaney S, Fox E, Weigel BJ
Pediatr Blood Cancer 2018 Aug;65(8):e27077. Epub 2018 Apr 25 doi: 10.1002/pbc.27077. PMID: 29693796Free PMC Article

Diagnosis

Cost-effectiveness of gilteritinib for relapsed/refractory FLT3(mut+) acute myeloid leukemia.
Pandya BJ, Qi CZ, Garnham A, Yang H, Shah MV, Zeidan AM
J Manag Care Spec Pharm 2021 Oct;27(10):1469-1481. doi: 10.18553/jmcp.2021.27.10.1469. PMID: 34595955Free PMC Article
Progress Update in Pediatric Renal Tumors.
Jain J, Sutton KS, Hong AL
Curr Oncol Rep 2021 Feb 16;23(3):33. doi: 10.1007/s11912-021-01016-y. PMID: 33591402
Adult Langerhans cell histiocytosis presenting with multisystem involvement and sarcomatoid features: a case report.
Aguirre LE, Schwartz I, Chapman J, Larsen MF, Alencar A
J Med Case Rep 2020 Sep 27;14(1):169. doi: 10.1186/s13256-020-02460-3. PMID: 32979930Free PMC Article
Autologous Stem Cell Transplantation for Children With Renal Tumors, and Adults With Wilms Tumor: Retrospective Analysis of the Japanese Transplant Registry Unified Management Program.
Kobayashi R, Inoue M, Takahashi Y, Kikuta A, Ogawa A, Koga Y, Koh K, Hashii Y, Hara J, Kato K, Tabuchi K, Matsumoto K
J Pediatr Hematol Oncol 2020 May;42(4):251-255. doi: 10.1097/MPH.0000000000001779. PMID: 32134841
Phase I Clinical Trial of Ipilimumab in Pediatric Patients with Advanced Solid Tumors.
Merchant MS, Wright M, Baird K, Wexler LH, Rodriguez-Galindo C, Bernstein D, Delbrook C, Lodish M, Bishop R, Wolchok JD, Streicher H, Mackall CL
Clin Cancer Res 2016 Mar 15;22(6):1364-70. Epub 2015 Nov 3 doi: 10.1158/1078-0432.CCR-15-0491. PMID: 26534966Free PMC Article

Therapy

Cost-effectiveness of gilteritinib for relapsed/refractory FLT3(mut+) acute myeloid leukemia.
Pandya BJ, Qi CZ, Garnham A, Yang H, Shah MV, Zeidan AM
J Manag Care Spec Pharm 2021 Oct;27(10):1469-1481. doi: 10.18553/jmcp.2021.27.10.1469. PMID: 34595955Free PMC Article
Translating Knowledge About the Immune Microenvironment of Gastrointestinal Stromal Tumors into Effective Clinical Strategies.
Chantharasamee J, Adashek JJ, Wong K, Eckardt MA, Chmielowski B, Dry S, Eilber FC, Singh AS
Curr Treat Options Oncol 2021 Jan 5;22(1):9. doi: 10.1007/s11864-020-00806-z. PMID: 33400014
Safety and Efficacy of Anlotinib, a Multikinase Angiogenesis Inhibitor, in Patients with Refractory Metastatic Soft-Tissue Sarcoma.
Chi Y, Fang Z, Hong X, Yao Y, Sun P, Wang G, Du F, Sun Y, Wu Q, Qu G, Wang S, Song J, Yu J, Lu Y, Zhu X, Niu X, He Z, Wang J, Yu H, Cai J
Clin Cancer Res 2018 Nov 1;24(21):5233-5238. Epub 2018 Jun 12 doi: 10.1158/1078-0432.CCR-17-3766. PMID: 29895706
A phase 1 study of cabozantinib in children and adolescents with recurrent or refractory solid tumors, including CNS tumors: Trial ADVL1211, a report from the Children's Oncology Group.
Chuk MK, Widemann BC, Minard CG, Liu X, Kim A, Bernhardt MB, Kudgus RA, Reid JM, Voss SD, Blaney S, Fox E, Weigel BJ
Pediatr Blood Cancer 2018 Aug;65(8):e27077. Epub 2018 Apr 25 doi: 10.1002/pbc.27077. PMID: 29693796Free PMC Article
Phase 1/2 study of immunotherapy with dendritic cells pulsed with autologous tumor lysate in patients with refractory bone and soft tissue sarcoma.
Miwa S, Nishida H, Tanzawa Y, Takeuchi A, Hayashi K, Yamamoto N, Mizukoshi E, Nakamoto Y, Kaneko S, Tsuchiya H
Cancer 2017 May 1;123(9):1576-1584. Epub 2017 Feb 27 doi: 10.1002/cncr.30606. PMID: 28241093

Prognosis

Cost-effectiveness of gilteritinib for relapsed/refractory FLT3(mut+) acute myeloid leukemia.
Pandya BJ, Qi CZ, Garnham A, Yang H, Shah MV, Zeidan AM
J Manag Care Spec Pharm 2021 Oct;27(10):1469-1481. doi: 10.18553/jmcp.2021.27.10.1469. PMID: 34595955Free PMC Article
Progress Update in Pediatric Renal Tumors.
Jain J, Sutton KS, Hong AL
Curr Oncol Rep 2021 Feb 16;23(3):33. doi: 10.1007/s11912-021-01016-y. PMID: 33591402
Translating Knowledge About the Immune Microenvironment of Gastrointestinal Stromal Tumors into Effective Clinical Strategies.
Chantharasamee J, Adashek JJ, Wong K, Eckardt MA, Chmielowski B, Dry S, Eilber FC, Singh AS
Curr Treat Options Oncol 2021 Jan 5;22(1):9. doi: 10.1007/s11864-020-00806-z. PMID: 33400014
Autologous Stem Cell Transplantation for Children With Renal Tumors, and Adults With Wilms Tumor: Retrospective Analysis of the Japanese Transplant Registry Unified Management Program.
Kobayashi R, Inoue M, Takahashi Y, Kikuta A, Ogawa A, Koga Y, Koh K, Hashii Y, Hara J, Kato K, Tabuchi K, Matsumoto K
J Pediatr Hematol Oncol 2020 May;42(4):251-255. doi: 10.1097/MPH.0000000000001779. PMID: 32134841
Safety and Efficacy of Anlotinib, a Multikinase Angiogenesis Inhibitor, in Patients with Refractory Metastatic Soft-Tissue Sarcoma.
Chi Y, Fang Z, Hong X, Yao Y, Sun P, Wang G, Du F, Sun Y, Wu Q, Qu G, Wang S, Song J, Yu J, Lu Y, Zhu X, Niu X, He Z, Wang J, Yu H, Cai J
Clin Cancer Res 2018 Nov 1;24(21):5233-5238. Epub 2018 Jun 12 doi: 10.1158/1078-0432.CCR-17-3766. PMID: 29895706

Clinical prediction guides

Cost-effectiveness of gilteritinib for relapsed/refractory FLT3(mut+) acute myeloid leukemia.
Pandya BJ, Qi CZ, Garnham A, Yang H, Shah MV, Zeidan AM
J Manag Care Spec Pharm 2021 Oct;27(10):1469-1481. doi: 10.18553/jmcp.2021.27.10.1469. PMID: 34595955Free PMC Article
Phase 1/2 study of immunotherapy with dendritic cells pulsed with autologous tumor lysate in patients with refractory bone and soft tissue sarcoma.
Miwa S, Nishida H, Tanzawa Y, Takeuchi A, Hayashi K, Yamamoto N, Mizukoshi E, Nakamoto Y, Kaneko S, Tsuchiya H
Cancer 2017 May 1;123(9):1576-1584. Epub 2017 Feb 27 doi: 10.1002/cncr.30606. PMID: 28241093
Phase I Clinical Trial of Ipilimumab in Pediatric Patients with Advanced Solid Tumors.
Merchant MS, Wright M, Baird K, Wexler LH, Rodriguez-Galindo C, Bernstein D, Delbrook C, Lodish M, Bishop R, Wolchok JD, Streicher H, Mackall CL
Clin Cancer Res 2016 Mar 15;22(6):1364-70. Epub 2015 Nov 3 doi: 10.1158/1078-0432.CCR-15-0491. PMID: 26534966Free PMC Article
A phase I trial and pharmacokinetic study of aflibercept (VEGF Trap) in children with refractory solid tumors: a children's oncology group phase I consortium report.
Glade Bender J, Blaney SM, Borinstein S, Reid JM, Baruchel S, Ahern C, Ingle AM, Yamashiro DJ, Chen A, Weigel B, Adamson PC, Park JR
Clin Cancer Res 2012 Sep 15;18(18):5081-9. Epub 2012 Jul 12 doi: 10.1158/1078-0432.CCR-12-0078. PMID: 22791883Free PMC Article

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