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Recurrent Appendix Adenocarcinoma

MedGen UID:
1793983
•Concept ID:
C5557542
•
Neoplastic Process

Definition

The reemergence of appendix adenocarcinoma after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Appendix Adenocarcinoma

Professional guidelines

PubMed

Mucinous appendiceal neoplasms and pseudomyxoma peritonei: Morphological and clinical findings, differential diagnosis, and prognosis.
Akay E, Arslan A, Eren SK, Özhan N, Karaman H
Indian J Pathol Microbiol 2022 Jul-Sep;65(3):565-571. doi: 10.4103/ijpm.ijpm_827_21. PMID: 35900483
Guideline No. 408: Management of Gestational Trophoblastic Diseases.
Eiriksson L, Dean E, Sebastianelli A, Salvador S, Comeau R, Jang JH, Bouchard-Fortier G, Osborne R, Sauthier P
J Obstet Gynaecol Can 2021 Jan;43(1):91-105.e1. doi: 10.1016/j.jogc.2020.03.001. PMID: 33384141
Treatment patterns and outcomes in goblet cell carcinoid tumors of the appendix.
Fields AC, Lu P, Enzinger A, Goldberg J, Irani J, Bleday R, Nash G, Melnitchouk N
J Surg Oncol 2019 Dec;120(7):1096-1101. Epub 2019 Oct 8 doi: 10.1002/jso.25723. PMID: 31592538Free PMC Article

Recent clinical studies

Etiology

Gastrointestinal stromal tumors: a comprehensive radiological review.
Inoue A, Ota S, Yamasaki M, Batsaikhan B, Furukawa A, Watanabe Y
Jpn J Radiol 2022 Nov;40(11):1105-1120. Epub 2022 Jul 9 doi: 10.1007/s11604-022-01305-x. PMID: 35809209Free PMC Article
Neuroendocrine neoplasms of the appendix, colon and rectum.
Volante M, Grillo F, Massa F, Maletta F, Mastracci L, Campora M, Ferro J, Vanoli A, Papotti M
Pathologica 2021 Feb;113(1):19-27. doi: 10.32074/1591-951X-230. PMID: 33686307Free PMC Article
Guideline No. 408: Management of Gestational Trophoblastic Diseases.
Eiriksson L, Dean E, Sebastianelli A, Salvador S, Comeau R, Jang JH, Bouchard-Fortier G, Osborne R, Sauthier P
J Obstet Gynaecol Can 2021 Jan;43(1):91-105.e1. doi: 10.1016/j.jogc.2020.03.001. PMID: 33384141
Nivolumab plus ipilimumab as first-line treatment for advanced non-small-cell lung cancer (CheckMate 012): results of an open-label, phase 1, multicohort study.
Hellmann MD, Rizvi NA, Goldman JW, Gettinger SN, Borghaei H, Brahmer JR, Ready NE, Gerber DE, Chow LQ, Juergens RA, Shepherd FA, Laurie SA, Geese WJ, Agrawal S, Young TC, Li X, Antonia SJ
Lancet Oncol 2017 Jan;18(1):31-41. Epub 2016 Dec 5 doi: 10.1016/S1470-2045(16)30624-6. PMID: 27932067Free PMC Article
Pseudomyxoma peritonei.
Hinson FL, Ambrose NS
Br J Surg 1998 Oct;85(10):1332-9. doi: 10.1046/j.1365-2168.1998.00882.x. PMID: 9782010

Diagnosis

Gastrointestinal stromal tumors: a comprehensive radiological review.
Inoue A, Ota S, Yamasaki M, Batsaikhan B, Furukawa A, Watanabe Y
Jpn J Radiol 2022 Nov;40(11):1105-1120. Epub 2022 Jul 9 doi: 10.1007/s11604-022-01305-x. PMID: 35809209Free PMC Article
The Role of Microorganisms in Appendiceal Pseudomyxoma Peritonei: A Review.
Khamzina Y, King MC, Nieroda C, Merrell DS, Sardi A, Gushchin V
Curr Oncol 2022 May 16;29(5):3576-3584. doi: 10.3390/curroncol29050289. PMID: 35621679Free PMC Article
Neuroendocrine neoplasms of the appendix, colon and rectum.
Volante M, Grillo F, Massa F, Maletta F, Mastracci L, Campora M, Ferro J, Vanoli A, Papotti M
Pathologica 2021 Feb;113(1):19-27. doi: 10.32074/1591-951X-230. PMID: 33686307Free PMC Article
Guideline No. 408: Management of Gestational Trophoblastic Diseases.
Eiriksson L, Dean E, Sebastianelli A, Salvador S, Comeau R, Jang JH, Bouchard-Fortier G, Osborne R, Sauthier P
J Obstet Gynaecol Can 2021 Jan;43(1):91-105.e1. doi: 10.1016/j.jogc.2020.03.001. PMID: 33384141
Pseudomyxoma peritonei.
Hinson FL, Ambrose NS
Br J Surg 1998 Oct;85(10):1332-9. doi: 10.1046/j.1365-2168.1998.00882.x. PMID: 9782010

Therapy

Iterative Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy for Recurrent Mucinous Adenocarcinoma of the Appendix.
Lopez-Ramirez F, Gushchin V, Sittig M, King MC, Baron E, Nikiforchin A, Nieroda C, Sardi A
Ann Surg Oncol 2022 Jun;29(6):3390-3401. Epub 2022 Feb 8 doi: 10.1245/s10434-021-11233-1. PMID: 35133518
Guideline No. 408: Management of Gestational Trophoblastic Diseases.
Eiriksson L, Dean E, Sebastianelli A, Salvador S, Comeau R, Jang JH, Bouchard-Fortier G, Osborne R, Sauthier P
J Obstet Gynaecol Can 2021 Jan;43(1):91-105.e1. doi: 10.1016/j.jogc.2020.03.001. PMID: 33384141
A case report of appendix mucinous adenocarcinoma that recurred after additional surgery and a brief literature review.
Chen W, Ye JW, Tan XP, Peng X, Zhang Y, Liang JL, Huang MJ
BMC Surg 2020 Aug 10;20(1):182. doi: 10.1186/s12893-020-00842-4. PMID: 32778094Free PMC Article
Nivolumab plus ipilimumab as first-line treatment for advanced non-small-cell lung cancer (CheckMate 012): results of an open-label, phase 1, multicohort study.
Hellmann MD, Rizvi NA, Goldman JW, Gettinger SN, Borghaei H, Brahmer JR, Ready NE, Gerber DE, Chow LQ, Juergens RA, Shepherd FA, Laurie SA, Geese WJ, Agrawal S, Young TC, Li X, Antonia SJ
Lancet Oncol 2017 Jan;18(1):31-41. Epub 2016 Dec 5 doi: 10.1016/S1470-2045(16)30624-6. PMID: 27932067Free PMC Article
Pseudomyxoma peritonei.
Hinson FL, Ambrose NS
Br J Surg 1998 Oct;85(10):1332-9. doi: 10.1046/j.1365-2168.1998.00882.x. PMID: 9782010

Prognosis

Gastrointestinal stromal tumors: a comprehensive radiological review.
Inoue A, Ota S, Yamasaki M, Batsaikhan B, Furukawa A, Watanabe Y
Jpn J Radiol 2022 Nov;40(11):1105-1120. Epub 2022 Jul 9 doi: 10.1007/s11604-022-01305-x. PMID: 35809209Free PMC Article
Neuroendocrine neoplasms of the appendix, colon and rectum.
Volante M, Grillo F, Massa F, Maletta F, Mastracci L, Campora M, Ferro J, Vanoli A, Papotti M
Pathologica 2021 Feb;113(1):19-27. doi: 10.32074/1591-951X-230. PMID: 33686307Free PMC Article
Guideline No. 408: Management of Gestational Trophoblastic Diseases.
Eiriksson L, Dean E, Sebastianelli A, Salvador S, Comeau R, Jang JH, Bouchard-Fortier G, Osborne R, Sauthier P
J Obstet Gynaecol Can 2021 Jan;43(1):91-105.e1. doi: 10.1016/j.jogc.2020.03.001. PMID: 33384141
Nivolumab plus ipilimumab as first-line treatment for advanced non-small-cell lung cancer (CheckMate 012): results of an open-label, phase 1, multicohort study.
Hellmann MD, Rizvi NA, Goldman JW, Gettinger SN, Borghaei H, Brahmer JR, Ready NE, Gerber DE, Chow LQ, Juergens RA, Shepherd FA, Laurie SA, Geese WJ, Agrawal S, Young TC, Li X, Antonia SJ
Lancet Oncol 2017 Jan;18(1):31-41. Epub 2016 Dec 5 doi: 10.1016/S1470-2045(16)30624-6. PMID: 27932067Free PMC Article
Pseudomyxoma peritonei.
Hinson FL, Ambrose NS
Br J Surg 1998 Oct;85(10):1332-9. doi: 10.1046/j.1365-2168.1998.00882.x. PMID: 9782010

Clinical prediction guides

Mucinous appendiceal neoplasms and pseudomyxoma peritonei: Morphological and clinical findings, differential diagnosis, and prognosis.
Akay E, Arslan A, Eren SK, Özhan N, Karaman H
Indian J Pathol Microbiol 2022 Jul-Sep;65(3):565-571. doi: 10.4103/ijpm.ijpm_827_21. PMID: 35900483
Gastrointestinal stromal tumors: a comprehensive radiological review.
Inoue A, Ota S, Yamasaki M, Batsaikhan B, Furukawa A, Watanabe Y
Jpn J Radiol 2022 Nov;40(11):1105-1120. Epub 2022 Jul 9 doi: 10.1007/s11604-022-01305-x. PMID: 35809209Free PMC Article
Iterative Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy for Recurrent Mucinous Adenocarcinoma of the Appendix.
Lopez-Ramirez F, Gushchin V, Sittig M, King MC, Baron E, Nikiforchin A, Nieroda C, Sardi A
Ann Surg Oncol 2022 Jun;29(6):3390-3401. Epub 2022 Feb 8 doi: 10.1245/s10434-021-11233-1. PMID: 35133518
Controversies in appendiceal pathology: mucinous and goblet cell neoplasms.
Orr CE, Yantiss RK
Pathology 2022 Mar;54(2):167-176. Epub 2021 Nov 23 doi: 10.1016/j.pathol.2021.09.003. PMID: 34836648
Guideline No. 408: Management of Gestational Trophoblastic Diseases.
Eiriksson L, Dean E, Sebastianelli A, Salvador S, Comeau R, Jang JH, Bouchard-Fortier G, Osborne R, Sauthier P
J Obstet Gynaecol Can 2021 Jan;43(1):91-105.e1. doi: 10.1016/j.jogc.2020.03.001. PMID: 33384141

Recent systematic reviews

Mixed Adenoneuroendocrine Carcinoma (MANEC) of the Gallbladder: A Systematic Review of Outcomes Following Surgical Management.
Machairas N, Paspala A, Frountzas M, Tsilimigras DI, Moris D, Ntomi V, Tsapralis D, Schizas D
In Vivo 2019 Nov-Dec;33(6):1721-1726. doi: 10.21873/invivo.11662. PMID: 31662496Free PMC Article
Systematic review and meta-analysis of appendiceal carcinoid tumors in children.
Njere I, Smith LL, Thurairasa D, Malik R, Jeffrey I, Okoye B, Sinha C
Pediatr Blood Cancer 2018 Aug;65(8):e27069. Epub 2018 May 10 doi: 10.1002/pbc.27069. PMID: 29745005
Chemoradiotherapy versus chemoradiotherapy plus surgery for esophageal cancer.
Vellayappan BA, Soon YY, Ku GY, Leong CN, Lu JJ, Tey JC
Cochrane Database Syst Rev 2017 Aug 22;8(8):CD010511. doi: 10.1002/14651858.CD010511.pub2. PMID: 28829911Free PMC Article
Perforation in appendiceal well-differentiated carcinoid and goblet cell tumors: impact on prognosis? A systematic review.
Madani A, van der Bilt JD, Consten EC, Vriens MR, Borel Rinkes IH
Ann Surg Oncol 2015 Mar;22(3):959-65. Epub 2014 Sep 5 doi: 10.1245/s10434-014-4023-9. PMID: 25190118

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