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Perisylvian FDG hypermetabolism

MedGen UID:
1814206
•Concept ID:
C5676628
•
Finding
Synonym: Perisylvian hypermetabolism in FDG PET
 
HPO: HP:0025699

Definition

18F-fluorodeoxyglucose (FDG) positron emission tomography and computed tomography (FDG-PET/CT) evaluates the glucose metabolism of the brain. FDG uptake is interpreted to represent glycolysis. This term therefore represents an abnormally increased FDG uptake (increased glucose metabolism) in the region of the brain that surrounds the Sylvian fissure. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPerisylvian FDG hypermetabolism

Recent clinical studies

Etiology

(18)F-FDG-PET patterns of surgical success and failure in mesial temporal lobe epilepsy.
Chassoux F, Artiges E, Semah F, Laurent A, Landré E, Turak B, Gervais P, Helal BO, Devaux B
Neurology 2017 Mar 14;88(11):1045-1053. Epub 2017 Feb 10 doi: 10.1212/WNL.0000000000003714. PMID: 28188304
Default mode network hypometabolism in epileptic encephalopathies with CSWS.
Ligot N, Archambaud F, Trotta N, Goldman S, Van Bogaert P, Chiron C, De Tiège X
Epilepsy Res 2014 Jul;108(5):861-71. Epub 2014 Mar 27 doi: 10.1016/j.eplepsyres.2014.03.014. PMID: 24746674

Prognosis

(18)F-FDG-PET patterns of surgical success and failure in mesial temporal lobe epilepsy.
Chassoux F, Artiges E, Semah F, Laurent A, Landré E, Turak B, Gervais P, Helal BO, Devaux B
Neurology 2017 Mar 14;88(11):1045-1053. Epub 2017 Feb 10 doi: 10.1212/WNL.0000000000003714. PMID: 28188304

Clinical prediction guides

(18)F-FDG-PET patterns of surgical success and failure in mesial temporal lobe epilepsy.
Chassoux F, Artiges E, Semah F, Laurent A, Landré E, Turak B, Gervais P, Helal BO, Devaux B
Neurology 2017 Mar 14;88(11):1045-1053. Epub 2017 Feb 10 doi: 10.1212/WNL.0000000000003714. PMID: 28188304

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