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Atrioventricular valve regurgitation

MedGen UID:
1815102
•Concept ID:
C5706196
•
Pathologic Function
HPO: HP:0034376

Definition

Regurgitation of a heart valve that controls blood flow from a an atrium to a ventricle, including mitral, tricuspid, or, rarely, single atrioventicular valve. [from HPO]

Professional guidelines

PubMed

Prenatal Diagnosis and Management of Single-Ventricle Heart Disease.
Freud LR, Seed M
Can J Cardiol 2022 Jul;38(7):897-908. Epub 2022 Apr 13 doi: 10.1016/j.cjca.2022.04.003. PMID: 35429589
Management of the adult Fontan patient.
Rodriguez FH, Book WM
Heart 2020 Jan;106(2):105-110. Epub 2019 Oct 29 doi: 10.1136/heartjnl-2019-314937. PMID: 31662332
Current options and outcomes for the management of atrioventricular septal defect.
Shuhaiber JH, Ho SY, Rigby M, Sethia B
Eur J Cardiothorac Surg 2009 May;35(5):891-900. Epub 2009 Feb 24 doi: 10.1016/j.ejcts.2009.01.009. PMID: 19243971

Recent clinical studies

Etiology

Natural and Modified History of Atrioventricular Valve Regurgitation in Patients With Fontan Circulation.
King G, Buratto E, Celermajer DS, Grigg L, Alphonso N, Robertson T, Bullock A, Ayer J, Iyengar A, d'Udekem Y, Konstantinov IE
J Am Coll Cardiol 2022 May 10;79(18):1832-1845. Epub 2022 Mar 21 doi: 10.1016/j.jacc.2022.02.022. PMID: 35331598
Atrioventricular Valve Regurgitation in Single Ventricle Heart Disease: A Common Problem Associated With Progressive Deterioration and Mortality.
Tseng SY, Siddiqui S, Di Maria MV, Hill GD, Lubert AM, Kutty S, Opotowsky AR, Possner M, Morales DLS, Quintessenza JA, Alsaied T
J Am Heart Assoc 2020 Jun 2;9(11):e015737. Epub 2020 May 16 doi: 10.1161/JAHA.119.015737. PMID: 32419552Free PMC Article
Atrioventricular valve closure in Fontan palliation.
King G, Winlaw DS, Alphonso N, Andrews D, Finucance K, Konstantinov IE, d'Udekem Y
Eur J Cardiothorac Surg 2020 May 1;57(5):945-950. doi: 10.1093/ejcts/ezz324. PMID: 31755928
Management of the adult Fontan patient.
Rodriguez FH, Book WM
Heart 2020 Jan;106(2):105-110. Epub 2019 Oct 29 doi: 10.1136/heartjnl-2019-314937. PMID: 31662332
Atrioventricular valve regurgitation in the fetus with atrioventricular canal defect: transition from prenatal to postnatal life.
Davey B, Thacker D, Rychik J
Pediatr Cardiol 2013;34(8):1797-802. Epub 2013 May 12 doi: 10.1007/s00246-013-0711-7. PMID: 23666083Free PMC Article

Diagnosis

A Computational Framework for Atrioventricular Valve Modeling Using Open-Source Software.
Wu W, Ching S, Maas SA, Lasso A, Sabin P, Weiss JA, Jolley MA
J Biomech Eng 2022 Oct 1;144(10) doi: 10.1115/1.4054485. PMID: 35510823Free PMC Article
Prenatal Diagnosis and Management of Single-Ventricle Heart Disease.
Freud LR, Seed M
Can J Cardiol 2022 Jul;38(7):897-908. Epub 2022 Apr 13 doi: 10.1016/j.cjca.2022.04.003. PMID: 35429589
Relationship of Ventricular Morphology and Atrioventricular Valve Function to Long-Term Outcomes Following Fontan Procedures.
Moon J, Shen L, Likosky DS, Sood V, Hobbs RD, Sassalos P, Romano JC, Ohye RG, Bove EL, Si MS
J Am Coll Cardiol 2020 Jul 28;76(4):419-431. doi: 10.1016/j.jacc.2020.05.059. PMID: 32703513Free PMC Article
Management of the adult Fontan patient.
Rodriguez FH, Book WM
Heart 2020 Jan;106(2):105-110. Epub 2019 Oct 29 doi: 10.1136/heartjnl-2019-314937. PMID: 31662332
Atrioventricular valve regurgitation in the fetus with atrioventricular canal defect: transition from prenatal to postnatal life.
Davey B, Thacker D, Rychik J
Pediatr Cardiol 2013;34(8):1797-802. Epub 2013 May 12 doi: 10.1007/s00246-013-0711-7. PMID: 23666083Free PMC Article

Therapy

Natural and Modified History of Atrioventricular Valve Regurgitation in Patients With Fontan Circulation.
King G, Buratto E, Celermajer DS, Grigg L, Alphonso N, Robertson T, Bullock A, Ayer J, Iyengar A, d'Udekem Y, Konstantinov IE
J Am Coll Cardiol 2022 May 10;79(18):1832-1845. Epub 2022 Mar 21 doi: 10.1016/j.jacc.2022.02.022. PMID: 35331598
Single-centre outcome of extracorporeal membrane oxygenation after the neonatal Norwood procedure.
Mayr B, Kido T, Holder S, Wallner M, Vodiskar J, Strbad M, Ruf B, Hager A, Ewert P, Hörer J, Lange R, Ono M
Eur J Cardiothorac Surg 2022 Aug 3;62(3) doi: 10.1093/ejcts/ezac129. PMID: 35304610
Long-term results of concomitant atrioventricular valve intervention and the Fontan operation.
Yang Y, Feng Z, Ma K, Zhang S, Zhang B, Qi L, Wang G, Li S
Eur J Cardiothorac Surg 2021 Apr 29;59(4):832-838. doi: 10.1093/ejcts/ezaa464. PMID: 33538305
Relationship of Ventricular Morphology and Atrioventricular Valve Function to Long-Term Outcomes Following Fontan Procedures.
Moon J, Shen L, Likosky DS, Sood V, Hobbs RD, Sassalos P, Romano JC, Ohye RG, Bove EL, Si MS
J Am Coll Cardiol 2020 Jul 28;76(4):419-431. doi: 10.1016/j.jacc.2020.05.059. PMID: 32703513Free PMC Article
Atrioventricular Valve Regurgitation in Single Ventricle Heart Disease: A Common Problem Associated With Progressive Deterioration and Mortality.
Tseng SY, Siddiqui S, Di Maria MV, Hill GD, Lubert AM, Kutty S, Opotowsky AR, Possner M, Morales DLS, Quintessenza JA, Alsaied T
J Am Heart Assoc 2020 Jun 2;9(11):e015737. Epub 2020 May 16 doi: 10.1161/JAHA.119.015737. PMID: 32419552Free PMC Article

Prognosis

Prenatal Diagnosis and Management of Single-Ventricle Heart Disease.
Freud LR, Seed M
Can J Cardiol 2022 Jul;38(7):897-908. Epub 2022 Apr 13 doi: 10.1016/j.cjca.2022.04.003. PMID: 35429589
Atrioventricular Valve Function Predicts Reintervention in Complete Atrioventricular Septal Defect.
Ijsselhof R, Gauvreau K, Nido PD, Nathan M
World J Pediatr Congenit Heart Surg 2020 Mar;11(2):247-248. doi: 10.1177/2150135119893648. PMID: 32093554Free PMC Article
Management of the adult Fontan patient.
Rodriguez FH, Book WM
Heart 2020 Jan;106(2):105-110. Epub 2019 Oct 29 doi: 10.1136/heartjnl-2019-314937. PMID: 31662332
Fetal cardiovascular hemodynamics in twin-twin transfusion syndrome.
Wohlmuth C, Gardiner HM, Diehl W, Hecher K
Acta Obstet Gynecol Scand 2016 Jun;95(6):664-71. Epub 2016 Mar 15 doi: 10.1111/aogs.12871. PMID: 26872246
Atrioventricular valve regurgitation in the fetus with atrioventricular canal defect: transition from prenatal to postnatal life.
Davey B, Thacker D, Rychik J
Pediatr Cardiol 2013;34(8):1797-802. Epub 2013 May 12 doi: 10.1007/s00246-013-0711-7. PMID: 23666083Free PMC Article

Clinical prediction guides

Revisiting predictors of worse atrioventricular valve and left ventricular systolic function following pacemaker therapy.
Sasaki K, Togashi D, Nakajima I, Nakayama Y, Harada T, Akashi YJ
Pacing Clin Electrophysiol 2023 Dec;46(12):1643-1651. Epub 2023 Oct 30 doi: 10.1111/pace.14862. PMID: 37904603
Natural and Modified History of Atrioventricular Valve Regurgitation in Patients With Fontan Circulation.
King G, Buratto E, Celermajer DS, Grigg L, Alphonso N, Robertson T, Bullock A, Ayer J, Iyengar A, d'Udekem Y, Konstantinov IE
J Am Coll Cardiol 2022 May 10;79(18):1832-1845. Epub 2022 Mar 21 doi: 10.1016/j.jacc.2022.02.022. PMID: 35331598
Atrioventricular Valve Function Predicts Reintervention in Complete Atrioventricular Septal Defect.
Ijsselhof R, Gauvreau K, Nido PD, Nathan M
World J Pediatr Congenit Heart Surg 2020 Mar;11(2):247-248. doi: 10.1177/2150135119893648. PMID: 32093554Free PMC Article
Fetal cardiovascular hemodynamics in twin-twin transfusion syndrome.
Wohlmuth C, Gardiner HM, Diehl W, Hecher K
Acta Obstet Gynecol Scand 2016 Jun;95(6):664-71. Epub 2016 Mar 15 doi: 10.1111/aogs.12871. PMID: 26872246
Atrioventricular valve regurgitation in the fetus with atrioventricular canal defect: transition from prenatal to postnatal life.
Davey B, Thacker D, Rychik J
Pediatr Cardiol 2013;34(8):1797-802. Epub 2013 May 12 doi: 10.1007/s00246-013-0711-7. PMID: 23666083Free PMC Article

Recent systematic reviews

Ventricular morphology of single-ventricle hearts has a significant impact on outcomes after Fontan palliation: a meta-analysis.
Ponzoni M, Azzolina D, Vedovelli L, Gregori D, Di Salvo G, D'Udekem Y, Vida V, Padalino MA
Eur J Cardiothorac Surg 2022 Nov 3;62(6) doi: 10.1093/ejcts/ezac535. PMID: 36367236
Modified Single-Patch versus Two-Patch Repair for Atrioventricular Septal Defect: A Systematic Review and Meta-Analysis.
Loomba RS, Flores S, Villarreal EG, Bronicki RA, Anderson RH
World J Pediatr Congenit Heart Surg 2019 Sep;10(5):616-623. doi: 10.1177/2150135119859882. PMID: 31496417
Risk factors for death or heart transplantation in single-ventricle physiology (tricuspid atresia, pulmonary atresia, and heterotaxy): A systematic review and meta-analysis.
Kulkarni A, Patel N, Singh TP, Mossialos E, Mehra MR
J Heart Lung Transplant 2019 Jul;38(7):739-747. Epub 2019 Apr 4 doi: 10.1016/j.healun.2019.04.001. PMID: 31006521
Predicting long-term mortality after Fontan procedures: A risk score based on 6707 patients from 28 studies.
Alsaied T, Bokma JP, Engel ME, Kuijpers JM, Hanke SP, Zuhlke L, Zhang B, Veldtman GR
Congenit Heart Dis 2017 Jul;12(4):393-398. Epub 2017 May 8 doi: 10.1111/chd.12468. PMID: 28480627

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