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Purulent synovial fluid

MedGen UID:
1842126
•Concept ID:
C5826785
•
Finding
HPO: HP:0034939

Definition

The synovial fluid (also known as synovia, i.e., the fluid found in the cavities of synovial joints) contains increased quantities of white blood cells. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPurulent synovial fluid

Professional guidelines

PubMed

Clinical efficacy of arthroscopy combined with irrigation and drainage in the treatment of brucellosis of the hip.
Zhou P, Li S, Zhao M, Shao H, Zhang P
Int Orthop 2023 Nov;47(11):2751-2756. Epub 2023 Aug 10 doi: 10.1007/s00264-023-05926-3. PMID: 37561152
Which Minor Criteria is the Most Accurate Predictor for the Diagnosis of Hip and Knee Periprosthetic Joint Infection in the Asian Population?
Kuo FC, Lin PC, Yen SH, Tan TL, Wu CT, Wang JW
J Arthroplasty 2022 Oct;37(10):2076-2081. Epub 2022 May 7 doi: 10.1016/j.arth.2022.05.002. PMID: 35537614
The 2018 Definition of Periprosthetic Hip and Knee Infection: An Evidence-Based and Validated Criteria.
Parvizi J, Tan TL, Goswami K, Higuera C, Della Valle C, Chen AF, Shohat N
J Arthroplasty 2018 May;33(5):1309-1314.e2. Epub 2018 Feb 26 doi: 10.1016/j.arth.2018.02.078. PMID: 29551303

Recent clinical studies

Etiology

Is DAIR Still an Effective Way to Eradicate Acute Prosthetic Joint Infections? Our Experience in the Jordanian Royal Medical Services.
Ghnaimat M, Alyamani A, Obeidat M, Jbarat A, Abushahot M
Med Arch 2021 Dec;75(6):451-455. doi: 10.5455/medarh.2021.75.451-455. PMID: 35169373Free PMC Article
Leukocyte Esterase: Metal-on-Metal Failure and Periprosthetic Joint Infection.
Tischler EH, Plummer DR, Chen AF, Della Valle CJ, Parvizi J
J Arthroplasty 2016 Oct;31(10):2260-3. Epub 2016 Mar 15 doi: 10.1016/j.arth.2016.03.012. PMID: 27094243
Interleukin-6 in serum and in synovial fluid enhances the differentiation between periprosthetic joint infection and aseptic loosening.
Randau TM, Friedrich MJ, Wimmer MD, Reichert B, Kuberra D, Stoffel-Wagner B, Limmer A, Wirtz DC, Gravius S
PLoS One 2014;9(2):e89045. Epub 2014 Feb 21 doi: 10.1371/journal.pone.0089045. PMID: 24586496Free PMC Article
Acute septic arthritis due to Streptococcus sanguis.
Papaioannides D, Boniatsi L, Korantzopoulos P, Sinapidis D, Giotis C
Med Princ Pract 2006;15(1):77-9. doi: 10.1159/000089391. PMID: 16340233
Septic arthritis in patients followed-up in neonatal intensive care unit.
Kabak S, Halici M, Akcakus M, Cetin N, Narin N
Pediatr Int 2002 Dec;44(6):652-7. doi: 10.1046/j.1442-200x.2002.01649.x. PMID: 12421264

Diagnosis

Evaluation and interpretation of prosthetic joint infection diagnostic investigations.
Trebse R, Roskar S
Int Orthop 2021 Apr;45(4):847-855. Epub 2021 Feb 8 doi: 10.1007/s00264-021-04958-x. PMID: 33555351
Septic arthritis due to non-tuberculous mycobacterium without effusion.
Lam V, Theyyunni N
Am J Emerg Med 2021 May;43:287.e5-287.e7. Epub 2020 Sep 23 doi: 10.1016/j.ajem.2020.09.043. PMID: 33010992
Leukocyte Esterase: Metal-on-Metal Failure and Periprosthetic Joint Infection.
Tischler EH, Plummer DR, Chen AF, Della Valle CJ, Parvizi J
J Arthroplasty 2016 Oct;31(10):2260-3. Epub 2016 Mar 15 doi: 10.1016/j.arth.2016.03.012. PMID: 27094243
Interleukin-6 in serum and in synovial fluid enhances the differentiation between periprosthetic joint infection and aseptic loosening.
Randau TM, Friedrich MJ, Wimmer MD, Reichert B, Kuberra D, Stoffel-Wagner B, Limmer A, Wirtz DC, Gravius S
PLoS One 2014;9(2):e89045. Epub 2014 Feb 21 doi: 10.1371/journal.pone.0089045. PMID: 24586496Free PMC Article
Synovial fluid cell analysis.
Dougados M
Baillieres Clin Rheumatol 1996 Aug;10(3):519-34. doi: 10.1016/s0950-3579(96)80047-1. PMID: 8876957

Therapy

Acute osteomyelitis of the patella due to Pseudomonas aeruginosa in an immunocompetent child: A case report.
Kamiya Y, Mishima K, Tanaka T, Sawamura K, Matsushita M, Imagama S
Medicine (Baltimore) 2023 Feb 17;102(7):e33012. doi: 10.1097/MD.0000000000033012. PMID: 36800616Free PMC Article
Is DAIR Still an Effective Way to Eradicate Acute Prosthetic Joint Infections? Our Experience in the Jordanian Royal Medical Services.
Ghnaimat M, Alyamani A, Obeidat M, Jbarat A, Abushahot M
Med Arch 2021 Dec;75(6):451-455. doi: 10.5455/medarh.2021.75.451-455. PMID: 35169373Free PMC Article
Leukocyte Esterase: Metal-on-Metal Failure and Periprosthetic Joint Infection.
Tischler EH, Plummer DR, Chen AF, Della Valle CJ, Parvizi J
J Arthroplasty 2016 Oct;31(10):2260-3. Epub 2016 Mar 15 doi: 10.1016/j.arth.2016.03.012. PMID: 27094243
Interleukin-6 in serum and in synovial fluid enhances the differentiation between periprosthetic joint infection and aseptic loosening.
Randau TM, Friedrich MJ, Wimmer MD, Reichert B, Kuberra D, Stoffel-Wagner B, Limmer A, Wirtz DC, Gravius S
PLoS One 2014;9(2):e89045. Epub 2014 Feb 21 doi: 10.1371/journal.pone.0089045. PMID: 24586496Free PMC Article
Acute septic arthritis due to Streptococcus sanguis.
Papaioannides D, Boniatsi L, Korantzopoulos P, Sinapidis D, Giotis C
Med Princ Pract 2006;15(1):77-9. doi: 10.1159/000089391. PMID: 16340233

Prognosis

Acute osteomyelitis of the patella due to Pseudomonas aeruginosa in an immunocompetent child: A case report.
Kamiya Y, Mishima K, Tanaka T, Sawamura K, Matsushita M, Imagama S
Medicine (Baltimore) 2023 Feb 17;102(7):e33012. doi: 10.1097/MD.0000000000033012. PMID: 36800616Free PMC Article
Evaluation and interpretation of prosthetic joint infection diagnostic investigations.
Trebse R, Roskar S
Int Orthop 2021 Apr;45(4):847-855. Epub 2021 Feb 8 doi: 10.1007/s00264-021-04958-x. PMID: 33555351
Leukocyte Esterase: Metal-on-Metal Failure and Periprosthetic Joint Infection.
Tischler EH, Plummer DR, Chen AF, Della Valle CJ, Parvizi J
J Arthroplasty 2016 Oct;31(10):2260-3. Epub 2016 Mar 15 doi: 10.1016/j.arth.2016.03.012. PMID: 27094243
Septic arthritis in patients followed-up in neonatal intensive care unit.
Kabak S, Halici M, Akcakus M, Cetin N, Narin N
Pediatr Int 2002 Dec;44(6):652-7. doi: 10.1046/j.1442-200x.2002.01649.x. PMID: 12421264

Clinical prediction guides

Is DAIR Still an Effective Way to Eradicate Acute Prosthetic Joint Infections? Our Experience in the Jordanian Royal Medical Services.
Ghnaimat M, Alyamani A, Obeidat M, Jbarat A, Abushahot M
Med Arch 2021 Dec;75(6):451-455. doi: 10.5455/medarh.2021.75.451-455. PMID: 35169373Free PMC Article
Leukocyte Esterase: Metal-on-Metal Failure and Periprosthetic Joint Infection.
Tischler EH, Plummer DR, Chen AF, Della Valle CJ, Parvizi J
J Arthroplasty 2016 Oct;31(10):2260-3. Epub 2016 Mar 15 doi: 10.1016/j.arth.2016.03.012. PMID: 27094243
Septic arthritis in patients followed-up in neonatal intensive care unit.
Kabak S, Halici M, Akcakus M, Cetin N, Narin N
Pediatr Int 2002 Dec;44(6):652-7. doi: 10.1046/j.1442-200x.2002.01649.x. PMID: 12421264
Synovial fluid cell analysis.
Dougados M
Baillieres Clin Rheumatol 1996 Aug;10(3):519-34. doi: 10.1016/s0950-3579(96)80047-1. PMID: 8876957

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