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Postoperative hemorrhage

MedGen UID:
18591
•Concept ID:
C0032788
•
Pathologic Function
Synonyms: Blood Loss, Postoperative; Hemorrhage, Postoperative; Hemorrhages, Postoperative; Loss, Postoperative Blood; Postoperative Blood Loss; Postoperative Hemorrhage; Postoperative Hemorrhages
SNOMED CT: Postoperative hemorrhage (110265006); Postoperative bleeding (110265006); Hemorrhage postprocedure (110265006)

Definition

Bleeding occurring after completion of a surgical procedure, which may occur immediately or may be delayed, and which may or may not be wound related. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPostoperative hemorrhage

Professional guidelines

PubMed

Endovascular treatment of postoperative hemorrhage after pancreatectomy: a retrospective study.
Izumi H, Yoshii H, Fujino R, Takeo S, Nomura E, Mukai M, Suda S, Tomita K, Kamei S, Ogawa Y, Hasebe T, Makuuchi H
BMC Gastroenterol 2023 Nov 7;23(1):379. doi: 10.1186/s12876-023-03022-9. PMID: 37936060Free PMC Article
Management of Recurrent and Delayed Post-Tonsillectomy and Adenoidectomy Hemorrhage in Children.
Cheung PKF, Walton J, Hobson ML, Taylor P, Chin M, Boardman S, Cheng ATL, Birman CS
Ear Nose Throat J 2023 Apr;102(4):244-250. Epub 2021 Mar 9 doi: 10.1177/0145561321999594. PMID: 33689495
Delayed Postoperative Hemorrhage Complicating Major Supramesocolic Surgery Management and Outcomes.
Devant E, Girard E, Abba J, Ghelfi J, Sage PY, Sengel C, Risse O, Bricault I, Trilling B, Chirica M
World J Surg 2021 Aug;45(8):2432-2438. Epub 2021 Apr 17 doi: 10.1007/s00268-021-06116-1. PMID: 33866425

Recent clinical studies

Etiology

Postoperative Tonsillectomy Hemorrhage.
Wall JJ, Tay KY
Emerg Med Clin North Am 2018 May;36(2):415-426. Epub 2018 Feb 10 doi: 10.1016/j.emc.2017.12.009. PMID: 29622331
Perioperative management of anticoagulant and antiplatelet therapy.
Tafur A, Douketis J
Heart 2018 Sep;104(17):1461-1467. Epub 2017 Dec 7 doi: 10.1136/heartjnl-2016-310581. PMID: 29217632
Hemostasis in Tonsillectomy.
Mitchell RM, Parikh SR
Otolaryngol Clin North Am 2016 Jun;49(3):615-26. doi: 10.1016/j.otc.2016.03.008. PMID: 27267014
Postoperative gastrointestinal hemorrhage.
Jones S, May AK
Surg Clin North Am 2012 Apr;92(2):235-42, viii. Epub 2012 Feb 1 doi: 10.1016/j.suc.2012.01.002. PMID: 22414410
Postpancreatectomy hemorrhage (PPH): an International Study Group of Pancreatic Surgery (ISGPS) definition.
Wente MN, Veit JA, Bassi C, Dervenis C, Fingerhut A, Gouma DJ, Izbicki JR, Neoptolemos JP, Padbury RT, Sarr MG, Yeo CJ, Büchler MW
Surgery 2007 Jul;142(1):20-5. doi: 10.1016/j.surg.2007.02.001. PMID: 17629996

Diagnosis

Viscoelastic testing in cardiac surgery.
Agarwal S, Abdelmotieleb M
Transfusion 2020 Oct;60 Suppl 6:S52-S60. Epub 2020 Sep 21 doi: 10.1111/trf.16075. PMID: 32955756
Percutaneous management of paravalvular leaks.
Giblett JP, Rana BS, Shapiro LM, Calvert PA
Nat Rev Cardiol 2019 May;16(5):275-285. doi: 10.1038/s41569-018-0147-0. PMID: 30659248
Postoperative abdominal bleeding.
Tasu JP, Vesselle G, Herpe G, Ferrie JC, Chan P, Boucebci S, Velasco S
Diagn Interv Imaging 2015 Jul-Aug;96(7-8):823-31. Epub 2015 Jun 12 doi: 10.1016/j.diii.2015.03.013. PMID: 26078019
Universal definition of perioperative bleeding in adult cardiac surgery.
Dyke C, Aronson S, Dietrich W, Hofmann A, Karkouti K, Levi M, Murphy GJ, Sellke FW, Shore-Lesserson L, von Heymann C, Ranucci M
J Thorac Cardiovasc Surg 2014 May;147(5):1458-1463.e1. Epub 2013 Dec 9 doi: 10.1016/j.jtcvs.2013.10.070. PMID: 24332097
Postpancreatectomy hemorrhage (PPH): an International Study Group of Pancreatic Surgery (ISGPS) definition.
Wente MN, Veit JA, Bassi C, Dervenis C, Fingerhut A, Gouma DJ, Izbicki JR, Neoptolemos JP, Padbury RT, Sarr MG, Yeo CJ, Büchler MW
Surgery 2007 Jul;142(1):20-5. doi: 10.1016/j.surg.2007.02.001. PMID: 17629996

Therapy

Postoperative hemorrhage following pancreatic injury: Risk factors and clinical outcomes.
Wang K, Li K, Deng Y, Wang X, Yang C, Chu C, Li W, Li J, Ding W
J Hepatobiliary Pancreat Sci 2023 May;30(5):644-654. Epub 2022 Nov 3 doi: 10.1002/jhbp.1251. PMID: 36270802
Thrombectomy for anterior circulation stroke beyond 6 h from time last known well (AURORA): a systematic review and individual patient data meta-analysis.
Jovin TG, Nogueira RG, Lansberg MG, Demchuk AM, Martins SO, Mocco J, Ribo M, Jadhav AP, Ortega-Gutierrez S, Hill MD, Lima FO, Haussen DC, Brown S, Goyal M, Siddiqui AH, Heit JJ, Menon BK, Kemp S, Budzik R, Urra X, Marks MP, Costalat V, Liebeskind DS, Albers GW
Lancet 2022 Jan 15;399(10321):249-258. Epub 2021 Nov 11 doi: 10.1016/S0140-6736(21)01341-6. PMID: 34774198
Viscoelastic testing in cardiac surgery.
Agarwal S, Abdelmotieleb M
Transfusion 2020 Oct;60 Suppl 6:S52-S60. Epub 2020 Sep 21 doi: 10.1111/trf.16075. PMID: 32955756
Perioperative coagulopathy monitoring.
Jakoi A, Kumar N, Vaccaro A, Radcliff K
Musculoskelet Surg 2014 Jun;98(1):1-8. Epub 2013 Nov 27 doi: 10.1007/s12306-013-0307-7. PMID: 24281819
Aprotinin revisited.
Deanda A Jr, Spiess BD
J Thorac Cardiovasc Surg 2012 Nov;144(5):998-1002. Epub 2012 Jul 15 doi: 10.1016/j.jtcvs.2012.06.035. PMID: 22795461

Prognosis

Investigation of Adult Post-Tonsillectomy Hemorrhage Rates and the Impact of NSAID Use.
McLean JE, Hill CJ, Riddick JB, Folsom CR
Laryngoscope 2022 May;132(5):949-953. Epub 2021 Sep 2 doi: 10.1002/lary.29844. PMID: 34473351
Comparative Incidence of Postoperative Hemorrhage in Vitreoretinal Surgery in Patients on Anti-Coagulants.
Starr MR, Ammar MJ, Patel LG, Boucher N, Yonekawa Y, Garg SJ, Hsu J, Ho AC, Regillo CD, Chiang A
Ophthalmic Surg Lasers Imaging Retina 2021 Jul;52(7):374-379. Epub 2021 Jul 1 doi: 10.3928/23258160-20210628-03. PMID: 34309424
Outcomes of a Postoperative Data-Extraction Questionnaire After Adenotonsillectomy in Children.
Billings KR, Stake C, Arzu J, Lavin J
Laryngoscope 2021 Nov;131(11):E2821-E2826. Epub 2021 May 20 doi: 10.1002/lary.29626. PMID: 34014559
Current status of laparoscopic radical hilar cholangiocarcinoma in Mainland China.
Chen Y, Xu Y, Zhang Y
Biosci Trends 2020 Jul 17;14(3):168-173. Epub 2020 May 9 doi: 10.5582/bst.2020.03010. PMID: 32389939
Incidence of and Risk Factors and Reinterventions for Post-Pancreatoduodenectomy Hemorrhage: Retrospective Analysis.
Wang WG, Fu L, Babu SR, Wang L, Liang CP, Tian BL
Dig Surg 2018;35(1):19-27. Epub 2017 Apr 7 doi: 10.1159/000460263. PMID: 28384642

Clinical prediction guides

Development and validation of a postoperative bleeding complications prediction model in infective endocarditis.
Wang J, Hou J, Feng K, Wu H, Liu Q, Zhou Z, Li H, Luo L, Fu G, Shang L, Chen G, Huang S, Wu Z
Int J Cardiol 2024 Feb 1;396:131432. Epub 2023 Oct 11 doi: 10.1016/j.ijcard.2023.131432. PMID: 37827281
Postoperative hemorrhage following pancreatic injury: Risk factors and clinical outcomes.
Wang K, Li K, Deng Y, Wang X, Yang C, Chu C, Li W, Li J, Ding W
J Hepatobiliary Pancreat Sci 2023 May;30(5):644-654. Epub 2022 Nov 3 doi: 10.1002/jhbp.1251. PMID: 36270802
Management of Recurrent and Delayed Post-Tonsillectomy and Adenoidectomy Hemorrhage in Children.
Cheung PKF, Walton J, Hobson ML, Taylor P, Chin M, Boardman S, Cheng ATL, Birman CS
Ear Nose Throat J 2023 Apr;102(4):244-250. Epub 2021 Mar 9 doi: 10.1177/0145561321999594. PMID: 33689495
POSTOPERATIVE HEMORRHAGE AS A COMPLICATION OF A PARTIAL NEPHRECTOMY: FREQUENCY, FEATURES AND MANAGEMENT.
Styopushkin S, Chaikovskyi V, Chernylovskyi V, Sokolenkо R, Bondarenko D
Georgian Med News 2021 Apr;(313):12-20. PMID: 34103423
Prediction of Postoperative Blood Loss Using Thromboelastometry in Adult Cardiac Surgery: Cohort Study and Systematic Review.
Meesters MI, Burtman D, van de Ven PM, Boer C
J Cardiothorac Vasc Anesth 2018 Feb;32(1):141-150. Epub 2017 Aug 16 doi: 10.1053/j.jvca.2017.08.025. PMID: 29126688

Recent systematic reviews

The risk of aspirin induced postoperative hemorrhage: a systematic review and meta-analysis.
Ling X, Lin R, Chen Y, Nie C, Sheng L, Liu J, Han C, Ding Z
Expert Rev Gastroenterol Hepatol 2022 Oct;16(10):981-992. Epub 2022 Oct 24 doi: 10.1080/17474124.2022.2137489. PMID: 36245097
Thrombectomy for anterior circulation stroke beyond 6 h from time last known well (AURORA): a systematic review and individual patient data meta-analysis.
Jovin TG, Nogueira RG, Lansberg MG, Demchuk AM, Martins SO, Mocco J, Ribo M, Jadhav AP, Ortega-Gutierrez S, Hill MD, Lima FO, Haussen DC, Brown S, Goyal M, Siddiqui AH, Heit JJ, Menon BK, Kemp S, Budzik R, Urra X, Marks MP, Costalat V, Liebeskind DS, Albers GW
Lancet 2022 Jan 15;399(10321):249-258. Epub 2021 Nov 11 doi: 10.1016/S0140-6736(21)01341-6. PMID: 34774198
Systematic Review and Meta-Analysis of the Association Between Non-Steroidal Anti-Inflammatory Drugs and Operative Bleeding in the Perioperative Period.
Bongiovanni T, Lancaster E, Ledesma Y, Whitaker E, Steinman MA, Allen IE, Auerbach A, Wick E
J Am Coll Surg 2021 May;232(5):765-790.e1. Epub 2021 Jan 27 doi: 10.1016/j.jamcollsurg.2021.01.005. PMID: 33515678Free PMC Article
Interventions for treating post-extraction bleeding.
Kumbargere Nagraj S, Prashanti E, Aggarwal H, Lingappa A, Muthu MS, Kiran Kumar Krishanappa S, Hassan H
Cochrane Database Syst Rev 2018 Mar 4;3(3):CD011930. doi: 10.1002/14651858.CD011930.pub3. PMID: 29502332Free PMC Article
Subtotal cholecystectomy for "difficult gallbladders": systematic review and meta-analysis.
Elshaer M, Gravante G, Thomas K, Sorge R, Al-Hamali S, Ebdewi H
JAMA Surg 2015 Feb;150(2):159-68. doi: 10.1001/jamasurg.2014.1219. PMID: 25548894

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