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Metastatic Malignant Neoplasm in the Pericardium

MedGen UID:
195778
•Concept ID:
C0685120
•
Neoplastic Process
Synonyms: Metastatic malignant neoplasm of pericardium; Metastatic malignant neoplasm to pericardium; Metastatic Malignant Neoplasm to the Pericardium; Metastatic Neoplasm to the Pericardium; Secondary malignant neoplasm of pericardium
SNOMED CT: Secondary malignant neoplasm of pericardium (94484009); Metastatic malignant neoplasm to pericardium (94484009); Metastatic malignant neoplasm of pericardium (94484009)

Definition

A malignant neoplasm that has spread to the pericardium from another primary anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Malignant Neoplasm in the Pericardium

Professional guidelines

PubMed

A Clinico-Pathologic Approach to the Differential Diagnosis of Pericardial Tumors.
Krywanczyk AR, Tan CD, Rodriguez ER
Curr Cardiol Rep 2021 Jul 16;23(9):119. doi: 10.1007/s11886-021-01548-6. PMID: 34269901
Update on diagnosis and management of neoplastic pericardial disease.
Avondo S, Andreis A, Casula M, Imazio M
Expert Rev Cardiovasc Ther 2020 Sep;18(9):615-623. Epub 2020 Aug 25 doi: 10.1080/14779072.2020.1811087. PMID: 32797759
Pathohistological diagnosis and differential diagnosis.
Tischoff I, Neid M, Neumann V, Tannapfel A
Recent Results Cancer Res 2011;189:57-78. doi: 10.1007/978-3-642-10862-4_5. PMID: 21479896

Recent clinical studies

Etiology

Pericardial Mesotheliomas.
Arrossi AV
Adv Anat Pathol 2023 Jul 1;30(4):253-258. Epub 2023 Apr 27 doi: 10.1097/PAP.0000000000000399. PMID: 37104724
Hydrodissection of the Retro-Sternal Space to Protect the Pericardium During Sternal Cryoablation.
Autrusseau PA, Garnon J, Auloge P, Weiss J, Dalili D, Caudrelier J, Cazzato RL, Koch G, Gangi A
Cardiovasc Intervent Radiol 2020 Sep;43(9):1371-1377. Epub 2020 Jul 8 doi: 10.1007/s00270-020-02587-2. PMID: 32642988
Spectrum of CT Findings in Thoracic Extranodal Non-Hodgkin Lymphoma.
Bligh MP, Borgaonkar JN, Burrell SC, MacDonald DA, Manos D
Radiographics 2017 Mar-Apr;37(2):439-461. doi: 10.1148/rg.2017160077. PMID: 28287948
Pathohistological diagnosis and differential diagnosis.
Tischoff I, Neid M, Neumann V, Tannapfel A
Recent Results Cancer Res 2011;189:57-78. doi: 10.1007/978-3-642-10862-4_5. PMID: 21479896
Metastases of the heart and pericardium.
Silvestri F, Bussani R, Pavletic N, Mannone T
G Ital Cardiol 1997 Dec;27(12):1252-5. PMID: 9470058

Diagnosis

Pericardial Mesotheliomas.
Arrossi AV
Adv Anat Pathol 2023 Jul 1;30(4):253-258. Epub 2023 Apr 27 doi: 10.1097/PAP.0000000000000399. PMID: 37104724
Neoplastic Pericardial Disease.
Maleszewski JJ, Anavekar NS
Cardiol Clin 2017 Nov;35(4):589-600. Epub 2017 Sep 6 doi: 10.1016/j.ccl.2017.07.011. PMID: 29025549
Cardiotoxicity of anticancer treatments.
Ewer MS, Ewer SM
Nat Rev Cardiol 2015 Sep;12(9):547-58. Epub 2015 May 12 doi: 10.1038/nrcardio.2015.65. PMID: 25962976
Primary pericardial tumors.
Restrepo CS, Vargas D, Ocazionez D, Martínez-Jiménez S, Betancourt Cuellar SL, Gutierrez FR
Radiographics 2013 Oct;33(6):1613-30. doi: 10.1148/rg.336135512. PMID: 24108554
Malignant pericardial effusion.
Burazor I, Imazio M, Markel G, Adler Y
Cardiology 2013;124(4):224-32. Epub 2013 Apr 5 doi: 10.1159/000348559. PMID: 23571453

Therapy

The metastatic site does not influence PD-L1 expression in advanced non-small cell lung carcinoma.
Wang H, Agulnik J, Kasymjanova G, Fiset PO, Camilleri-Broet S, Redpath M, Cohen V, Small D, Pepe C, Sakr L, Spatz A
Lung Cancer 2019 Jun;132:36-38. Epub 2019 Apr 8 doi: 10.1016/j.lungcan.2019.04.009. PMID: 31097091
2015 update on the diagnosis and management of neoplastic pericardial disease.
Lestuzzi C, Berretta M, Tomkowski W
Expert Rev Cardiovasc Ther 2015 Apr;13(4):377-89. doi: 10.1586/14779072.2015.1025754. PMID: 25797903
Malignant pericardial effusion.
Burazor I, Imazio M, Markel G, Adler Y
Cardiology 2013;124(4):224-32. Epub 2013 Apr 5 doi: 10.1159/000348559. PMID: 23571453
Purulent pericarditis.
Kennedy C, McEvoy S
Ir J Med Sci 2009 Mar;178(1):97-9. Epub 2008 Jan 23 doi: 10.1007/s11845-008-0119-1. PMID: 18214575
Cardiac effects of noncardiac neoplasms.
Schoen FJ, Berger BM, Guerina NG
Cardiol Clin 1984 Nov;2(4):657-70. PMID: 6400009

Prognosis

Pericardial Mesotheliomas.
Arrossi AV
Adv Anat Pathol 2023 Jul 1;30(4):253-258. Epub 2023 Apr 27 doi: 10.1097/PAP.0000000000000399. PMID: 37104724
A Clinico-Pathologic Approach to the Differential Diagnosis of Pericardial Tumors.
Krywanczyk AR, Tan CD, Rodriguez ER
Curr Cardiol Rep 2021 Jul 16;23(9):119. doi: 10.1007/s11886-021-01548-6. PMID: 34269901
Primary pericardial tumors.
Restrepo CS, Vargas D, Ocazionez D, Martínez-Jiménez S, Betancourt Cuellar SL, Gutierrez FR
Radiographics 2013 Oct;33(6):1613-30. doi: 10.1148/rg.336135512. PMID: 24108554
Malignant pericardial effusion.
Burazor I, Imazio M, Markel G, Adler Y
Cardiology 2013;124(4):224-32. Epub 2013 Apr 5 doi: 10.1159/000348559. PMID: 23571453
Pericardial tumors.
Luk A, Ahn E, Vaideeswar P, Butany JW
Semin Diagn Pathol 2008 Feb;25(1):47-53. doi: 10.1053/j.semdp.2007.12.001. PMID: 18350922

Clinical prediction guides

Clinical Utility of [(18)F]FDG-PET /CT in Pericardial Disease.
Kim MS, Kim EK, Choi JY, Oh JK, Chang SA
Curr Cardiol Rep 2019 Aug 2;21(9):107. doi: 10.1007/s11886-019-1193-x. PMID: 31376028
The metastatic site does not influence PD-L1 expression in advanced non-small cell lung carcinoma.
Wang H, Agulnik J, Kasymjanova G, Fiset PO, Camilleri-Broet S, Redpath M, Cohen V, Small D, Pepe C, Sakr L, Spatz A
Lung Cancer 2019 Jun;132:36-38. Epub 2019 Apr 8 doi: 10.1016/j.lungcan.2019.04.009. PMID: 31097091
Spectrum of malignant pleural and pericardial disease on FDG PET/CT.
Makis W, Ciarallo A, Hickeson M, Rush C, Novales-Diaz JA, Derbekyan V, Laufer J, Stern J, Lisbona R
AJR Am J Roentgenol 2012 Mar;198(3):678-85. doi: 10.2214/AJR.11.7076. PMID: 22358009
Thoracic lymphoma.
North LB, Libshitz HI, Lorigan JG
Radiol Clin North Am 1990 Jul;28(4):745-62. PMID: 2190268
Malignant pericardial diseases: diagnosis and treatment.
Kralstein J, Frishman W
Am Heart J 1987 Mar;113(3):785-90. doi: 10.1016/0002-8703(87)90720-4. PMID: 3548297

Recent systematic reviews

A Systematic Review and Meta-Analysis of Prevalence and Outcomes of Cardiac Metastasis of Neuroendocrine Malignancies.
Hamza M, Manasrah N, Patel NN, Sattar Y, Patel B
Am J Cardiol 2023 May 1;194:86-92. Epub 2023 Mar 29 doi: 10.1016/j.amjcard.2023.02.011. PMID: 36996525
Primary and metastatic primitive neuroectodermal tumor of the heart: A systematic review.
Hajsadeghi S, Iranpour A, Amouei E, Tehrani NH, Ghavidel A, Ziaie H, Asadi O, Moradians V, Tayebi A, Mestres CA, Manqoutaei SA
Asian Cardiovasc Thorac Ann 2022 Sep;30(7):761-771. Epub 2022 Mar 21 doi: 10.1177/02184923221083434. PMID: 35306869
Intrapericardial instillation of bleomycin prevents recurrence of malignant pericardial effusions: Series of 46 cases and comprehensive literature review.
Lambert A, Salleron J, Kieffer A, Raymond P, Geoffrois L, Gavoille C
Bull Cancer 2020 Jul-Aug;107(7-8):756-762. Epub 2020 Jun 5 doi: 10.1016/j.bulcan.2020.04.010. PMID: 32513434

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