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Glossopharyngeal nerve disorder

MedGen UID:
199771
•Concept ID:
C0751941
•
Disease or Syndrome
Synonym: Glossopharyngeal nerve disease
SNOMED CT: Disorder of ninth nerve (80962007); Glossopharyngeal nerve lesion (80962007); Disorder of IXth cranial nerve (80962007); Disorder of glossopharyngeal nerve (80962007); Disorder of the ninth cranial nerve (80962007); Glossopharyngeal nerve disorder (80962007)
 
Monarch Initiative: MONDO:0002639

Definition

A non-neoplastic or neoplastic disorder affecting the glossopharyngeal nerve (ninth cranial nerve). [from NCI]

Professional guidelines

PubMed

Medication Management of Neuropathic Pain Disorders.
Fisher R, Clarkson E
Dent Clin North Am 2024 Jan;68(1):121-131. Epub 2023 Aug 30 doi: 10.1016/j.cden.2023.07.010. PMID: 37951629
CRANIAL NERVE HYPERFUNCTION SYNDROMES. MODERN APPROACHES TO DIAGNOSIS AND TREATMENT (REVIEW).
Sirko A, Chekha K, Mizyakina K
Georgian Med News 2020 Jun;(303):113-120. PMID: 32841192
Glossopharyngeal neuralgia: neurosurgical treatment and differential diagnosis.
Teixeira MJ, de Siqueira SR, Bor-Seng-Shu E
Acta Neurochir (Wien) 2008 May;150(5):471-5; discussion 475. Epub 2008 Feb 4 doi: 10.1007/s00701-007-1493-6. PMID: 18231706

Recent clinical studies

Etiology

Collet-Sicard syndrome: a scoping review.
Aguilera-Pena MP, Castiblanco MA, Osejo-Arcos V, Aponte-Caballero R, Gutierrez-Gomez S, Abaunza-Camacho JF, Guevara-Moriones N, Benavides-Burbano CA, Riveros-Castillo WM, Saavedra JM
Neurosurg Rev 2023 Sep 14;46(1):244. doi: 10.1007/s10143-023-02145-7. PMID: 37707587
Transient glossopharyngeal nerve palsy due to mandibular nerve block.
Papadopoulou M, Anastasakis S
BMJ Case Rep 2022 Jul 25;15(7) doi: 10.1136/bcr-2022-251033. PMID: 35878966Free PMC Article
Risk factors of post-tonsillectomy dysgeusia.
Kitaya S, Kikuchi T, Yahata I, Ikeda R, Nomura K, Kawase T, Katori Y
Auris Nasus Larynx 2020 Apr;47(2):238-241. Epub 2019 Jul 16 doi: 10.1016/j.anl.2019.07.005. PMID: 31324400
Sex, Gender, and Orofacial Pain.
Shaefer JR, Khawaja SN, Bavia PF
Dent Clin North Am 2018 Oct;62(4):665-682. Epub 2018 Aug 2 doi: 10.1016/j.cden.2018.06.001. PMID: 30189989
Glossopharyngeal neuralgia and radiosurgery.
Martínez-Álvarez R, Martínez-Moreno N, Kusak ME, Rey-Portolés G
J Neurosurg 2014 Dec;121 Suppl:222-5. doi: 10.3171/2014.8.GKS141273. PMID: 25434956

Diagnosis

Trigeminal and Glossopharyngeal Neuralgia.
Allam AK, Larkin MB, Sharma H, Viswanathan A
Neurol Clin 2024 May;42(2):585-598. Epub 2024 Jan 12 doi: 10.1016/j.ncl.2023.12.011. PMID: 38575268
Imaging of Cranial Neuralgias.
Kanekar S, Saif M, Kanekar S
Neurol Clin 2022 Aug;40(3):591-607. Epub 2022 Jun 28 doi: 10.1016/j.ncl.2022.02.008. PMID: 35871786
Neuropathic Orofacial Pain.
Christoforou J
Dent Clin North Am 2018 Oct;62(4):565-584. Epub 2018 Jul 31 doi: 10.1016/j.cden.2018.05.005. PMID: 30189983
Cranial Neuralgias.
Tepper SJ
Continuum (Minneap Minn) 2018 Aug;24(4, Headache):1157-1178. doi: 10.1212/CON.0000000000000637. PMID: 30074554
Cranial Neuralgias.
Cheshire WP Jr
Continuum (Minneap Minn) 2015 Aug;21(4 Headache):1072-85. doi: 10.1212/CON.0000000000000194. PMID: 26252592

Therapy

Current advances in the surgical treatment of glossopharyngeal neuralgia.
Berckemeyer MA, Suarez-Meade P, Carcelen MFV, Ricci MD, Cheshire WP, Trifiletti DM, Middlebrooks EH, Quinones-Hinojosa A, Grewal SS
Neurosurg Rev 2023 Feb 2;46(1):47. doi: 10.1007/s10143-023-01948-y. PMID: 36725770
Transient glossopharyngeal nerve palsy due to mandibular nerve block.
Papadopoulou M, Anastasakis S
BMJ Case Rep 2022 Jul 25;15(7) doi: 10.1136/bcr-2022-251033. PMID: 35878966Free PMC Article
Trigeminal and glossopharyngeal neuralgia.
Reddy GD, Viswanathan A
Neurol Clin 2014 May;32(2):539-52. Epub 2013 Dec 28 doi: 10.1016/j.ncl.2013.11.008. PMID: 24703544
Cranial neuralgias.
Hupp WS, Firriolo FJ
Dent Clin North Am 2013 Jul;57(3):481-95. Epub 2013 May 21 doi: 10.1016/j.cden.2013.04.009. PMID: 23809305
Vagolysis.
Hutchinson CD, Jardine DL, Hurrell M
Age Ageing 2008 Sep;37(5):602-4. Epub 2008 Jun 12 doi: 10.1093/ageing/afn105. PMID: 18556705

Prognosis

Lower cranial nerve syndromes: a review.
Gutierrez S, Warner T, McCormack E, Werner C, Mathkour M, Iwanaga J, Uz A, Dumont AS, Tubbs RS
Neurosurg Rev 2021 Jun;44(3):1345-1355. Epub 2020 Jul 8 doi: 10.1007/s10143-020-01344-w. PMID: 32638140
Glossopharyngeal neuralgia and radiosurgery.
Martínez-Álvarez R, Martínez-Moreno N, Kusak ME, Rey-Portolés G
J Neurosurg 2014 Dec;121 Suppl:222-5. doi: 10.3171/2014.8.GKS141273. PMID: 25434956
Vagolysis.
Hutchinson CD, Jardine DL, Hurrell M
Age Ageing 2008 Sep;37(5):602-4. Epub 2008 Jun 12 doi: 10.1093/ageing/afn105. PMID: 18556705
Imaging of the glossopharyngeal, vagus, and accessory nerves.
Larson TC 3rd, Aulino JM, Laine FJ
Semin Ultrasound CT MR 2002 Jun;23(3):238-55. doi: 10.1016/s0887-2171(02)90049-1. PMID: 12168999
The glossopharyngeal nerve, glossopharyngeal neuralgia and the Eagle's syndrome--current concepts and management.
Soh KB
Singapore Med J 1999 Oct;40(10):659-65. PMID: 10741197

Clinical prediction guides

Acute Taste Dysfunction in Oropharyngeal Cancer Patients after Transoral Robotic Surgery.
Tharakan T, Piccirillo JF, Miller B, Reed DR, Kallogjeri D, Paniello R, Puram SV, Jackson RS
Laryngoscope 2023 Dec;133(12):3520-3528. Epub 2023 Aug 8 doi: 10.1002/lary.30939. PMID: 37551882Free PMC Article
Current advances in the surgical treatment of glossopharyngeal neuralgia.
Berckemeyer MA, Suarez-Meade P, Carcelen MFV, Ricci MD, Cheshire WP, Trifiletti DM, Middlebrooks EH, Quinones-Hinojosa A, Grewal SS
Neurosurg Rev 2023 Feb 2;46(1):47. doi: 10.1007/s10143-023-01948-y. PMID: 36725770
Transient glossopharyngeal nerve palsy due to mandibular nerve block.
Papadopoulou M, Anastasakis S
BMJ Case Rep 2022 Jul 25;15(7) doi: 10.1136/bcr-2022-251033. PMID: 35878966Free PMC Article
Glossopharyngeal neuralgia and radiosurgery.
Martínez-Álvarez R, Martínez-Moreno N, Kusak ME, Rey-Portolés G
J Neurosurg 2014 Dec;121 Suppl:222-5. doi: 10.3171/2014.8.GKS141273. PMID: 25434956
Clinical manifestations of carotid dissection.
Baumgartner R, Bogousslavsky J
Front Neurol Neurosci 2005;20:70-76. doi: 10.1159/000088151. PMID: 17290113

Recent systematic reviews

Current advances in the surgical treatment of glossopharyngeal neuralgia.
Berckemeyer MA, Suarez-Meade P, Carcelen MFV, Ricci MD, Cheshire WP, Trifiletti DM, Middlebrooks EH, Quinones-Hinojosa A, Grewal SS
Neurosurg Rev 2023 Feb 2;46(1):47. doi: 10.1007/s10143-023-01948-y. PMID: 36725770
Cranial Nerve Disorders Associated With Immune Checkpoint Inhibitors.
Vogrig A, Muñiz-Castrillo S, Joubert B, Picard G, Rogemond V, Skowron F, Egri M, Desestret V, Tilikete C, Psimaras D, Ducray F, Honnorat J
Neurology 2021 Feb 9;96(6):e866-e875. Epub 2020 Dec 14 doi: 10.1212/WNL.0000000000011340. PMID: 33318162
Repeat Gamma Knife Radiosurgery for Recurrent Glossopharyngeal Neuralgia: A Systematic Review and Our Initial Experience.
Kaye J, Daggubati LC, Zeller S, McInerney J
Stereotact Funct Neurosurg 2020;98(5):324-330. Epub 2020 Aug 18 doi: 10.1159/000508541. PMID: 32810861
Glossopharyngeal Neuralgia Treatment Outcomes After Nerve Section, Microvascular Decompression, or Stereotactic Radiosurgery: A Systematic Review and Meta-Analysis.
Lu VM, Goyal A, Graffeo CS, Perry A, Jonker BP, Link MJ
World Neurosurg 2018 Dec;120:572-582.e7. Epub 2018 Sep 18 doi: 10.1016/j.wneu.2018.09.042. PMID: 30240868
Pharyngolaryngeal involvement by varicella-zoster virus.
Nisa L, Landis BN, Giger R, Leuchter I
J Voice 2013 Sep;27(5):636-41. Epub 2013 Jun 12 doi: 10.1016/j.jvoice.2013.02.011. PMID: 23769009

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