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Colorectal Intraepithelial Neoplasia

MedGen UID:
232094
•Concept ID:
C1333112
•
Neoplastic Process
Synonyms: Colorectal Dysplasia; Large Intestinal Dysplasia; Large Intestinal Intraepithelial Neoplasia

Definition

A precancerous neoplastic process that affects the colon or rectum. It is characterized by low or high grade dysplasia of the mucosal epithelium. There is no evidence of invasion. [from NCI]

Professional guidelines

PubMed

Expected value of artificial intelligence in gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement.
Messmann H, Bisschops R, Antonelli G, Libânio D, Sinonquel P, Abdelrahim M, Ahmad OF, Areia M, Bergman JJGHM, Bhandari P, Boskoski I, Dekker E, Domagk D, Ebigbo A, Eelbode T, Eliakim R, Häfner M, Haidry RJ, Jover R, Kaminski MF, Kuvaev R, Mori Y, Palazzo M, Repici A, Rondonotti E, Rutter MD, Saito Y, Sharma P, Spada C, Spadaccini M, Veitch A, Gralnek IM, Hassan C, Dinis-Ribeiro M
Endoscopy 2022 Dec;54(12):1211-1231. Epub 2022 Oct 21 doi: 10.1055/a-1950-5694. PMID: 36270318
Colorectal Cancer Screening Methods and Molecular Markers for Early Detection.
Wu Z, Li Y, Zhang Y, Hu H, Wu T, Liu S, Chen W, Xie S, Lu Z
Technol Cancer Res Treat 2020 Jan-Dec;19:1533033820980426. doi: 10.1177/1533033820980426. PMID: 33353503Free PMC Article
Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management.
Eaton JE, Talwalkar JA, Lazaridis KN, Gores GJ, Lindor KD
Gastroenterology 2013 Sep;145(3):521-36. Epub 2013 Jul 1 doi: 10.1053/j.gastro.2013.06.052. PMID: 23827861Free PMC Article

Recent clinical studies

Diagnosis

Second-harmonic imaging microscopy for identifying colorectal intraepithelial neoplasia.
Li LH, Jiang WZ, Kang DY, Liu X, Li HS, Guan GX, Zhuo SM, Chen ZF, Chen JX
J Microsc 2018 Jul;271(1):31-35. Epub 2018 Mar 5 doi: 10.1111/jmi.12690. PMID: 29505679

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