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High Grade Gastric Intraepithelial Neoplasia

MedGen UID:
232284
•Concept ID:
C1334004
•
Neoplastic Process
Synonyms: High-Grade Gastric Glandular Intraepithelial Neoplasia; High-Grade Gastric Glandular Intraepithelial Neoplasia (Dysplasia); High-Grade Gastric Intraepithelial Neoplasia (Dysplasia)

Definition

A gastric intraepithelial lesion characterized by the presence of neoplastic cells that are cuboidal with a high nucleus to cytoplasmic ratio, prominent nucleoli, significant architectural changes, and increased number of mitotic figures. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHigh Grade Gastric Intraepithelial Neoplasia

Professional guidelines

PubMed

Expected value of artificial intelligence in gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement.
Messmann H, Bisschops R, Antonelli G, Libânio D, Sinonquel P, Abdelrahim M, Ahmad OF, Areia M, Bergman JJGHM, Bhandari P, Boskoski I, Dekker E, Domagk D, Ebigbo A, Eelbode T, Eliakim R, Häfner M, Haidry RJ, Jover R, Kaminski MF, Kuvaev R, Mori Y, Palazzo M, Repici A, Rondonotti E, Rutter MD, Saito Y, Sharma P, Spada C, Spadaccini M, Veitch A, Gralnek IM, Hassan C, Dinis-Ribeiro M
Endoscopy 2022 Dec;54(12):1211-1231. Epub 2022 Oct 21 doi: 10.1055/a-1950-5694. PMID: 36270318
Diagnosis and management of gastric dysplasia.
Sung JK
Korean J Intern Med 2016 Mar;31(2):201-9. Epub 2016 Feb 26 doi: 10.3904/kjim.2016.021. PMID: 26932397Free PMC Article
A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas.
Basturk O, Hong SM, Wood LD, Adsay NV, Albores-Saavedra J, Biankin AV, Brosens LA, Fukushima N, Goggins M, Hruban RH, Kato Y, Klimstra DS, Klöppel G, Krasinskas A, Longnecker DS, Matthaei H, Offerhaus GJ, Shimizu M, Takaori K, Terris B, Yachida S, Esposito I, Furukawa T; Baltimore Consensus Meeting
Am J Surg Pathol 2015 Dec;39(12):1730-41. doi: 10.1097/PAS.0000000000000533. PMID: 26559377Free PMC Article

Recent clinical studies

Diagnosis

VENet: Variational energy network for gland segmentation of pathological images and early gastric cancer diagnosis of whole slide images.
Zhang S, Yuan Z, Zhou X, Wang H, Chen B, Wang Y
Comput Methods Programs Biomed 2024 Jun;250:108178. Epub 2024 Apr 21 doi: 10.1016/j.cmpb.2024.108178. PMID: 38652995

Prognosis

VENet: Variational energy network for gland segmentation of pathological images and early gastric cancer diagnosis of whole slide images.
Zhang S, Yuan Z, Zhou X, Wang H, Chen B, Wang Y
Comput Methods Programs Biomed 2024 Jun;250:108178. Epub 2024 Apr 21 doi: 10.1016/j.cmpb.2024.108178. PMID: 38652995

Clinical prediction guides

VENet: Variational energy network for gland segmentation of pathological images and early gastric cancer diagnosis of whole slide images.
Zhang S, Yuan Z, Zhou X, Wang H, Chen B, Wang Y
Comput Methods Programs Biomed 2024 Jun;250:108178. Epub 2024 Apr 21 doi: 10.1016/j.cmpb.2024.108178. PMID: 38652995

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