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Non-Neoplastic Mediastinal Disorder

MedGen UID:
233237
•Concept ID:
C1335020
•
Disease or Syndrome
Synonym: Non-Neoplastic Mediastinal Disease

Definition

A non-neoplastic disorder that affects the structures of the mediastinum. Representative examples include mediastinitis and thymic hyperplasia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNon-Neoplastic Mediastinal Disorder

Professional guidelines

PubMed

The Hematological Differential Diagnosis of Mediastinal Masses.
Aljudi A, Weinzierl E, Elkhalifa M, Park S
Clin Lab Med 2021 Sep;41(3):389-404. Epub 2021 Jul 3 doi: 10.1016/j.cll.2021.03.011. PMID: 34304771

Recent clinical studies

Etiology

Non-Neoplastic Thoracic Cysts: A Clinicopathologic Study of 136 Cases.
Weissferdt A
Am J Surg Pathol 2023 Dec 1;47(12):1349-1363. Epub 2023 Aug 29 doi: 10.1097/PAS.0000000000002115. PMID: 37642507
Clinical practices for non-neoplastic thymic lesions: Results from a multidisciplinary cohort.
Joubert V, Chalabreysse L, Gamondes D, Tronc F, Maury JM, Girard N
Lung Cancer 2022 Apr;166:76-83. Epub 2022 Feb 22 doi: 10.1016/j.lungcan.2022.02.004. PMID: 35227953
Clinicopathological Analysis of Mediastinal Masses: A Mixed Bag of Non-Neoplastic and Neoplastic Etiologies.
Sharma P, Jha V, Kumar N, Kumar R, Mandal A
Turk Patoloji Derg 2017;33(1):37-46. doi: 10.5146/tjpath.2016.01371. PMID: 28044305
Acute lymphoblastic leukemia and lymphoma in the context of constitutional mismatch repair deficiency syndrome.
Ripperger T, Schlegelberger B
Eur J Med Genet 2016 Mar;59(3):133-42. Epub 2015 Dec 30 doi: 10.1016/j.ejmg.2015.12.014. PMID: 26743104
Non-neoplastic mediastinal cysts.
Zambudio AR, Lanzas JT, Calvo MJ, Fernández PJ, Paricio PP
Eur J Cardiothorac Surg 2002 Nov;22(5):712-6. doi: 10.1016/s1010-7940(02)00484-0. PMID: 12414035

Diagnosis

Clinical practices for non-neoplastic thymic lesions: Results from a multidisciplinary cohort.
Joubert V, Chalabreysse L, Gamondes D, Tronc F, Maury JM, Girard N
Lung Cancer 2022 Apr;166:76-83. Epub 2022 Feb 22 doi: 10.1016/j.lungcan.2022.02.004. PMID: 35227953
The Hematological Differential Diagnosis of Mediastinal Masses.
Aljudi A, Weinzierl E, Elkhalifa M, Park S
Clin Lab Med 2021 Sep;41(3):389-404. Epub 2021 Jul 3 doi: 10.1016/j.cll.2021.03.011. PMID: 34304771
Non-Neoplastic Mediastinal Cysts.
Syred K, Weissferdt A
Adv Anat Pathol 2020 Sep;27(5):294-302. doi: 10.1097/PAP.0000000000000261. PMID: 31972565
Non-neoplastic mediastinal cysts.
Zambudio AR, Lanzas JT, Calvo MJ, Fernández PJ, Paricio PP
Eur J Cardiothorac Surg 2002 Nov;22(5):712-6. doi: 10.1016/s1010-7940(02)00484-0. PMID: 12414035
Non-neoplastic pulmonary lymphoid lesions.
Travis WD, Galvin JR
Thorax 2001 Dec;56(12):964-71. doi: 10.1136/thorax.56.12.964. PMID: 11713361Free PMC Article

Therapy

Video-assisted thoracoscopic lobectomy: an unavoidable trend? A retrospective single-institution series of 410 cases.
Marty-Ané CH, Canaud L, Solovei L, Alric P, Berthet JP
Interact Cardiovasc Thorac Surg 2013 Jul;17(1):36-43. Epub 2013 Apr 16 doi: 10.1093/icvts/ivt146. PMID: 23592725Free PMC Article
Non-neoplastic pulmonary lymphoid lesions.
Travis WD, Galvin JR
Thorax 2001 Dec;56(12):964-71. doi: 10.1136/thorax.56.12.964. PMID: 11713361Free PMC Article

Prognosis

Non-Neoplastic Mediastinal Cysts.
Syred K, Weissferdt A
Adv Anat Pathol 2020 Sep;27(5):294-302. doi: 10.1097/PAP.0000000000000261. PMID: 31972565
Histological Diagnoses of Military Personnel Undergoing Lung Biopsy After Deployment to Southwest Asia.
Madar CS, Lewin-Smith MR, Franks TJ, Harley RA, Klaric JS, Morris MJ
Lung 2017 Aug;195(4):507-515. Epub 2017 May 23 doi: 10.1007/s00408-017-0009-2. PMID: 28536739
Clinicopathological Analysis of Mediastinal Masses: A Mixed Bag of Non-Neoplastic and Neoplastic Etiologies.
Sharma P, Jha V, Kumar N, Kumar R, Mandal A
Turk Patoloji Derg 2017;33(1):37-46. doi: 10.5146/tjpath.2016.01371. PMID: 28044305
Acute lymphoblastic leukemia and lymphoma in the context of constitutional mismatch repair deficiency syndrome.
Ripperger T, Schlegelberger B
Eur J Med Genet 2016 Mar;59(3):133-42. Epub 2015 Dec 30 doi: 10.1016/j.ejmg.2015.12.014. PMID: 26743104
Non-neoplastic mediastinal cysts.
Zambudio AR, Lanzas JT, Calvo MJ, Fernández PJ, Paricio PP
Eur J Cardiothorac Surg 2002 Nov;22(5):712-6. doi: 10.1016/s1010-7940(02)00484-0. PMID: 12414035

Clinical prediction guides

Clinical practices for non-neoplastic thymic lesions: Results from a multidisciplinary cohort.
Joubert V, Chalabreysse L, Gamondes D, Tronc F, Maury JM, Girard N
Lung Cancer 2022 Apr;166:76-83. Epub 2022 Feb 22 doi: 10.1016/j.lungcan.2022.02.004. PMID: 35227953
Histological Diagnoses of Military Personnel Undergoing Lung Biopsy After Deployment to Southwest Asia.
Madar CS, Lewin-Smith MR, Franks TJ, Harley RA, Klaric JS, Morris MJ
Lung 2017 Aug;195(4):507-515. Epub 2017 May 23 doi: 10.1007/s00408-017-0009-2. PMID: 28536739
Acute lymphoblastic leukemia and lymphoma in the context of constitutional mismatch repair deficiency syndrome.
Ripperger T, Schlegelberger B
Eur J Med Genet 2016 Mar;59(3):133-42. Epub 2015 Dec 30 doi: 10.1016/j.ejmg.2015.12.014. PMID: 26743104
Non-neoplastic mediastinal cysts.
Zambudio AR, Lanzas JT, Calvo MJ, Fernández PJ, Paricio PP
Eur J Cardiothorac Surg 2002 Nov;22(5):712-6. doi: 10.1016/s1010-7940(02)00484-0. PMID: 12414035
Primary mediastinal seminomas: evidence of single and multiple KIT mutations.
Przygodzki RM, Hubbs AE, Zhao FQ, O'Leary TJ
Lab Invest 2002 Oct;82(10):1369-75. doi: 10.1097/01.lab.0000032410.46986.7b. PMID: 12379771

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