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High Grade Cervical Glandular Intraepithelial Neoplasia

MedGen UID:
234348
•Concept ID:
C1334010
•
Neoplastic Process
Synonyms: H-CGIN - high grade cervical glandular intraepithelial neoplasia; High grade cervical glandular intraepithelial neoplasia
SNOMED CT: High grade cervical glandular intraepithelial neoplasia (769169008); H-CGIN - high grade cervical glandular intraepithelial neoplasia (769169008)

Definition

Cervical glandular intraepithelial neoplasia characterized by the presence of severe dysplastic changes. [from NCI]

Professional guidelines

PubMed

European consensus statement on expert colposcopy.
McGee AE, Alibegashvili T, Elfgren K, Frey B, Grigore M, Heinonen A, Jach R, Jariene K, Kesic V, Küppers V, Kyrgiou M, Leeson S, Louwers J, Mazurec M, Mergui J, Pedro A, Šavrova A, Siegler E, Tabuica U, Trojnarska D, Trzeszcz M, Turyna R, Volodko N, Cruickshank ME; European Federation for Colposcopy and Pathology of the Lower Genital Tract (EFC) and the European Society of Gynaecological Oncology (ESGO)
Eur J Obstet Gynecol Reprod Biol 2023 Nov;290:27-37. Epub 2023 Aug 31 doi: 10.1016/j.ejogrb.2023.08.369. PMID: 37716200
Management of cervical cytologic abnormalities.
Apgar BS, Brotzman G
Am Fam Physician 2004 Nov 15;70(10):1905-16. PMID: 15571057
Cervical squamous and glandular intraepithelial neoplasia: identification and current management approaches.
Wright VC
Salud Publica Mex 2003;45 Suppl 3:S417-29. doi: 10.1590/s0036-36342003000900016. PMID: 14746035

Recent clinical studies

Diagnosis

Detection of occult endocervical glandular dysplasia in cervical conization specimens for squamous lesions.
Sopracordevole F, Clemente N, Alessandrini L, Di Giuseppe J, Cigolot F, Buttignol M, Ciavattini A, Canzonieri V
Pathol Res Pract 2017 Mar;213(3):210-216. Epub 2017 Jan 12 doi: 10.1016/j.prp.2016.12.015. PMID: 28214204

Clinical prediction guides

Detection of occult endocervical glandular dysplasia in cervical conization specimens for squamous lesions.
Sopracordevole F, Clemente N, Alessandrini L, Di Giuseppe J, Cigolot F, Buttignol M, Ciavattini A, Canzonieri V
Pathol Res Pract 2017 Mar;213(3):210-216. Epub 2017 Jan 12 doi: 10.1016/j.prp.2016.12.015. PMID: 28214204
Evaluation of PTEN expression in cervical adenocarcinoma by tissue microarray.
El-Mansi MT, Williams AR
Int J Gynecol Cancer 2006 May-Jun;16(3):1254-60. doi: 10.1111/j.1525-1438.2006.00569.x. PMID: 16803514

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