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Hodgkin-Like Adult T-Cell Leukemia/Lymphoma

MedGen UID:
234354
•Concept ID:
C1334035
•
Neoplastic Process
Synonyms: Hodgkin's-Like Adult T-Cell Lymphoma/Leukemia; Hodgkin-Like Adult T-Cell Lymphoma/Leukemia

Definition

A rare morphologic variant of adult T-cell leukemia/lymphoma characterized by the presence of Hodgkin-like and Reed-Sternberg-like cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHodgkin-Like Adult T-Cell Leukemia/Lymphoma

Recent clinical studies

Diagnosis

Hodgkin-like adult T-cell leukemia/lymphoma that developed during the follow-up of HTLV-1 associated myelopathy/tropical spastic paraparesis.
Nakaya Y, Yoshida M, Tsutsumi M, Fuseya H, Horiuchi M, Yoshimura T, Hayashi Y, Nakao T, Koh KR, Niino D, Inoue T, Yamane T
J Clin Exp Hematop 2019 Sep 30;59(3):130-134. Epub 2019 Aug 8 doi: 10.3960/jslrt.19010. PMID: 31391405Free PMC Article
Prolonged lymphocytosis as the first manifestation of Hodgkin-like adult T-cell leukemia/lymphoma.
Bittencourt AL, Andrade AC, Requião C, Arruda MD, Araújo I
Braz J Infect Dis 2017 Jan-Feb;21(1):119-122. Epub 2016 Oct 24 doi: 10.1016/j.bjid.2016.09.005. PMID: 27789281Free PMC Article

Therapy

Epstein-Barr virus-associated post-transplant lymphoproliferative disorders after allogeneic peripheral blood stem cell transplantation for Hodgkin-like adult T-cell leukemia/lymphoma.
Yagi T, Ishikawa J, Aono N, Yamashita Y, Kusakabe S, Yoshinami T, Akazawa Y, Sakai D, Yamamoto S, Hamanaka Y, Masaie H, Sugimoto N, Yoshida H, Tomita Y, Imamura F
Int J Hematol 2012 Feb;95(2):214-6. Epub 2011 Dec 16 doi: 10.1007/s12185-011-0979-4. PMID: 22170229

Prognosis

Hodgkin-like adult T-cell leukemia/lymphoma that developed during the follow-up of HTLV-1 associated myelopathy/tropical spastic paraparesis.
Nakaya Y, Yoshida M, Tsutsumi M, Fuseya H, Horiuchi M, Yoshimura T, Hayashi Y, Nakao T, Koh KR, Niino D, Inoue T, Yamane T
J Clin Exp Hematop 2019 Sep 30;59(3):130-134. Epub 2019 Aug 8 doi: 10.3960/jslrt.19010. PMID: 31391405Free PMC Article
Prolonged lymphocytosis as the first manifestation of Hodgkin-like adult T-cell leukemia/lymphoma.
Bittencourt AL, Andrade AC, Requião C, Arruda MD, Araújo I
Braz J Infect Dis 2017 Jan-Feb;21(1):119-122. Epub 2016 Oct 24 doi: 10.1016/j.bjid.2016.09.005. PMID: 27789281Free PMC Article

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