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Splenic manifestation of hairy cell leukemia

MedGen UID:
234812
•Concept ID:
C1336064
•
Neoplastic Process
Synonyms: hairy cell leukaemia of spleen; hairy cell leukemia of spleen; spleen hairy cell leukaemia; spleen hairy cell leukemia; Splenic Manifestation of Hairy Cell Leukemia; splenic manifestation of hairy cell leukemia
 
Monarch Initiative: MONDO:0004104

Definition

Infiltration and expansion of the red pulp of the spleen by hairy cell leukemia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSplenic manifestation of hairy cell leukemia

Professional guidelines

PubMed

Inhibitor of BRAF(V600E) Mutation as a Treatment Option for Hairy Cell Leukemia With Deep Neutropenia and Infectious Complications.
Smirnova SY, Al-Radi LS, Moiseeva TN, Gemdzhian EG, Yakutik IA, Julhakyan HL, Novikov VA, Galstyan GM, Sudarikov AB
Clin Lymphoma Myeloma Leuk 2021 Jul;21(7):427-430. Epub 2021 Mar 3 doi: 10.1016/j.clml.2021.02.005. PMID: 33811006
Hairy cell leukaemia-variant: Disease features and treatment.
Matutes E, Martínez-Trillos A, Campo E
Best Pract Res Clin Haematol 2015 Dec;28(4):253-63. Epub 2015 Oct 8 doi: 10.1016/j.beha.2015.09.002. PMID: 26614904
Surgical pathology of the spleen: an approach to the differential diagnosis of splenic lymphomas and leukemias. Part II. Diseases of the red pulp.
Burke JS
Am J Surg Pathol 1981 Oct;5(7):681-94. PMID: 7039375

Curated

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Hairy Cell Leukemia, 2024

Recent clinical studies

Etiology

Inhibitor of BRAF(V600E) Mutation as a Treatment Option for Hairy Cell Leukemia With Deep Neutropenia and Infectious Complications.
Smirnova SY, Al-Radi LS, Moiseeva TN, Gemdzhian EG, Yakutik IA, Julhakyan HL, Novikov VA, Galstyan GM, Sudarikov AB
Clin Lymphoma Myeloma Leuk 2021 Jul;21(7):427-430. Epub 2021 Mar 3 doi: 10.1016/j.clml.2021.02.005. PMID: 33811006
Clinical presentations and complications of hairy cell leukemia.
Hoffman MA
Hematol Oncol Clin North Am 2006 Oct;20(5):1065-73. doi: 10.1016/j.hoc.2006.06.003. PMID: 16990107
Hairy cell leukemia: a retrospective study of 235 cases by the Italian Cooperative Group (ICGHCL) according to Jansen's clinical staging system.
Damasio EE, Spriano M, Repetto M, Vimercati AR, Rossi E, Occhini D, Marmont AM
Acta Haematol 1984;72(5):326-34. doi: 10.1159/000206409. PMID: 6441412

Diagnosis

A Review on Splenic Diffuse Red Pulp Small B-Cell Lymphoma.
Yilmaz E, Chhina A, Nava VE, Aggarwal A
Curr Oncol 2021 Dec 6;28(6):5148-5154. doi: 10.3390/curroncol28060431. PMID: 34940070Free PMC Article
How to Diagnose and Treat CD5-Positive Lymphomas Involving the Spleen.
Cabeçadas J, Nava VE, Ascensao JL, Gomes da Silva M
Curr Oncol 2021 Nov 11;28(6):4611-4633. doi: 10.3390/curroncol28060390. PMID: 34898558Free PMC Article
Hairy cell leukaemia-variant: Disease features and treatment.
Matutes E, Martínez-Trillos A, Campo E
Best Pract Res Clin Haematol 2015 Dec;28(4):253-63. Epub 2015 Oct 8 doi: 10.1016/j.beha.2015.09.002. PMID: 26614904
Clinical presentations and complications of hairy cell leukemia.
Hoffman MA
Hematol Oncol Clin North Am 2006 Oct;20(5):1065-73. doi: 10.1016/j.hoc.2006.06.003. PMID: 16990107
Pathology of peliosis.
Tsokos M, Erbersdobler A
Forensic Sci Int 2005 Apr 20;149(1):25-33. doi: 10.1016/j.forsciint.2004.05.010. PMID: 15734106

Therapy

Inhibitor of BRAF(V600E) Mutation as a Treatment Option for Hairy Cell Leukemia With Deep Neutropenia and Infectious Complications.
Smirnova SY, Al-Radi LS, Moiseeva TN, Gemdzhian EG, Yakutik IA, Julhakyan HL, Novikov VA, Galstyan GM, Sudarikov AB
Clin Lymphoma Myeloma Leuk 2021 Jul;21(7):427-430. Epub 2021 Mar 3 doi: 10.1016/j.clml.2021.02.005. PMID: 33811006
Hairy cell leukaemia-variant: Disease features and treatment.
Matutes E, Martínez-Trillos A, Campo E
Best Pract Res Clin Haematol 2015 Dec;28(4):253-63. Epub 2015 Oct 8 doi: 10.1016/j.beha.2015.09.002. PMID: 26614904
Hairy cell leukemia: current concepts.
Cannon T, Mobarek D, Wegge J, Tabbara IA
Cancer Invest 2008 Oct;26(8):860-5. doi: 10.1080/07357900801965034. PMID: 18798068

Prognosis

How to Diagnose and Treat CD5-Positive Lymphomas Involving the Spleen.
Cabeçadas J, Nava VE, Ascensao JL, Gomes da Silva M
Curr Oncol 2021 Nov 11;28(6):4611-4633. doi: 10.3390/curroncol28060390. PMID: 34898558Free PMC Article
Inhibitor of BRAF(V600E) Mutation as a Treatment Option for Hairy Cell Leukemia With Deep Neutropenia and Infectious Complications.
Smirnova SY, Al-Radi LS, Moiseeva TN, Gemdzhian EG, Yakutik IA, Julhakyan HL, Novikov VA, Galstyan GM, Sudarikov AB
Clin Lymphoma Myeloma Leuk 2021 Jul;21(7):427-430. Epub 2021 Mar 3 doi: 10.1016/j.clml.2021.02.005. PMID: 33811006
Hairy cell leukaemia-variant: Disease features and treatment.
Matutes E, Martínez-Trillos A, Campo E
Best Pract Res Clin Haematol 2015 Dec;28(4):253-63. Epub 2015 Oct 8 doi: 10.1016/j.beha.2015.09.002. PMID: 26614904
Hairy cell leukemia: current concepts.
Cannon T, Mobarek D, Wegge J, Tabbara IA
Cancer Invest 2008 Oct;26(8):860-5. doi: 10.1080/07357900801965034. PMID: 18798068
Clinical presentations and complications of hairy cell leukemia.
Hoffman MA
Hematol Oncol Clin North Am 2006 Oct;20(5):1065-73. doi: 10.1016/j.hoc.2006.06.003. PMID: 16990107

Clinical prediction guides

Inhibitor of BRAF(V600E) Mutation as a Treatment Option for Hairy Cell Leukemia With Deep Neutropenia and Infectious Complications.
Smirnova SY, Al-Radi LS, Moiseeva TN, Gemdzhian EG, Yakutik IA, Julhakyan HL, Novikov VA, Galstyan GM, Sudarikov AB
Clin Lymphoma Myeloma Leuk 2021 Jul;21(7):427-430. Epub 2021 Mar 3 doi: 10.1016/j.clml.2021.02.005. PMID: 33811006

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
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    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NCCN, 2024
      NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Hairy Cell Leukemia, 2024

    Consumer resources

    Reviews

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    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
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