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Invasive Lesion

MedGen UID:
272775
•Concept ID:
C1334278
•
Finding

Definition

A malignant cellular population that has increased in size and infiltrates the surrounding tissues. [from NCI]

Professional guidelines

PubMed

Review of high-risk features of cutaneous squamous cell carcinoma and discrepancies between the American Joint Committee on Cancer and NCCN Clinical Practice Guidelines In Oncology.
Skulsky SL, O'Sullivan B, McArdle O, Leader M, Roche M, Conlon PJ, O'Neill JP
Head Neck 2017 Mar;39(3):578-594. Epub 2016 Nov 24 doi: 10.1002/hed.24580. PMID: 27882625
Which treatment for large rectal adenoma? Preoperative assessment and therapeutic strategy.
Arezzo A, Arolfo S, Cravero F, Migliore M, Allaix ME, Morino M
Minim Invasive Ther Allied Technol 2014 Jan;23(1):21-7. Epub 2013 Sep 1 doi: 10.3109/13645706.2013.833117. PMID: 23992387
Management of pre-invasive cervical cancer in low-resource setting.
Chichareon SB
J Med Assoc Thai 2004 Oct;87 Suppl 3:S214-22. PMID: 21213526

Recent clinical studies

Etiology

Thin-slice computed tomography enables to classify pulmonary subsolid nodules into pre-invasive lesion/minimally invasive adenocarcinoma and invasive adenocarcinoma: a retrospective study.
Li M, Zhu L, Lv Y, Shen L, Han Y, Ye B
Sci Rep 2023 Apr 28;13(1):6999. doi: 10.1038/s41598-023-33803-x. PMID: 37117233Free PMC Article
Cervical Intraepithelial Neoplasia: Analyzing the Disease Present Exclusively in the Endocervical Canal.
Fonseca FV, Cordeiro MVG, Pozza AC, Maestri CA
Rev Bras Ginecol Obstet 2022 Apr;44(4):385-390. Epub 2022 Mar 11 doi: 10.1055/s-0042-1743102. PMID: 35276746Free PMC Article
Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma.
Risom T, Glass DR, Averbukh I, Liu CC, Baranski A, Kagel A, McCaffrey EF, Greenwald NF, Rivero-Gutiérrez B, Strand SH, Varma S, Kong A, Keren L, Srivastava S, Zhu C, Khair Z, Veis DJ, Deschryver K, Vennam S, Maley C, Hwang ES, Marks JR, Bendall SC, Colditz GA, West RB, Angelo M
Cell 2022 Jan 20;185(2):299-310.e18. doi: 10.1016/j.cell.2021.12.023. PMID: 35063072Free PMC Article
Molecular alterations of neuroendocrine tumours of the lung.
Rossi G, Bertero L, Marchiò C, Papotti M
Histopathology 2018 Jan;72(1):142-152. doi: 10.1111/his.13394. PMID: 29239031
Pulmonary preinvasive neoplasia.
Kerr KM
J Clin Pathol 2001 Apr;54(4):257-71. doi: 10.1136/jcp.54.4.257. PMID: 11304841Free PMC Article

Diagnosis

An introduction to the WHO 5th edition 2022 classification of testicular tumours.
Berney DM, Cree I, Rao V, Moch H, Srigley JR, Tsuzuki T, Amin MB, Comperat EM, Hartmann A, Menon S, Netto GJ, Rubin MA, Turajlic S, Raspollini MR, Tickoo SK
Histopathology 2022 Oct;81(4):459-466. Epub 2022 Jul 1 doi: 10.1111/his.14675. PMID: 35502823Free PMC Article
Molecular alterations of neuroendocrine tumours of the lung.
Rossi G, Bertero L, Marchiò C, Papotti M
Histopathology 2018 Jan;72(1):142-152. doi: 10.1111/his.13394. PMID: 29239031
Invasion in breast lesions: the role of the epithelial-stroma barrier.
Rakha EA, Miligy IM, Gorringe KL, Toss MS, Green AR, Fox SB, Schmitt FC, Tan PH, Tse GM, Badve S, Decker T, Vincent-Salomon A, Dabbs DJ, Foschini MP, Moreno F, Wentao Y, Geyer FC, Reis-Filho JS, Pinder SE, Lakhani SR, Ellis IO
Histopathology 2018 Jun;72(7):1075-1083. Epub 2018 Feb 13 doi: 10.1111/his.13446. PMID: 29197112
Benign mimickers of malignant breast lesions.
Spruill L
Semin Diagn Pathol 2016 Jan;33(1):2-12. Epub 2015 Sep 5 doi: 10.1053/j.semdp.2015.09.002. PMID: 26472694
DIPNECH: when to suggest this diagnosis on CT.
Chassagnon G, Favelle O, Marchand-Adam S, De Muret A, Revel MP
Clin Radiol 2015 Mar;70(3):317-25. Epub 2014 Nov 22 doi: 10.1016/j.crad.2014.10.012. PMID: 25465294

Therapy

Supervised machine learning enables non-invasive lesion characterization in primary prostate cancer with [(68)Ga]Ga-PSMA-11 PET/MRI.
Papp L, Spielvogel CP, Grubmüller B, Grahovac M, Krajnc D, Ecsedi B, Sareshgi RAM, Mohamad D, Hamboeck M, Rausch I, Mitterhauser M, Wadsak W, Haug AR, Kenner L, Mazal P, Susani M, Hartenbach S, Baltzer P, Helbich TH, Kramer G, Shariat SF, Beyer T, Hartenbach M, Hacker M
Eur J Nucl Med Mol Imaging 2021 Jun;48(6):1795-1805. Epub 2020 Dec 19 doi: 10.1007/s00259-020-05140-y. PMID: 33341915Free PMC Article
Post-operative radiotherapy for ductal carcinoma in situ of the breast.
Goodwin A, Parker S, Ghersi D, Wilcken N
Cochrane Database Syst Rev 2013 Nov 21;(11):CD000563. doi: 10.1002/14651858.CD000563.pub7. PMID: 24259251
Post-operative radiotherapy for ductal carcinoma in situ of the breast.
Goodwin A, Parker S, Ghersi D, Wilcken N
Cochrane Database Syst Rev 2009 Oct 7;(4):CD000563. doi: 10.1002/14651858.CD000563.pub6. PMID: 19821272
Post-operative radiotherapy for ductal carcinoma in situ of the breast.
Goodwin A, Parker S, Ghersi D, Wilcken N
Cochrane Database Syst Rev 2009 Jul 8;(3):CD000563. doi: 10.1002/14651858.CD000563.pub5. PMID: 19588320
Post-operative radiotherapy for ductal carcinoma in situ of the breast.
Goodwin A, Parker S, Ghersi D, Wilcken N
Cochrane Database Syst Rev 2009 Jan 21;(1):CD000563. doi: 10.1002/14651858.CD000563.pub4. PMID: 19160183

Prognosis

An introduction to the WHO 5th edition 2022 classification of testicular tumours.
Berney DM, Cree I, Rao V, Moch H, Srigley JR, Tsuzuki T, Amin MB, Comperat EM, Hartmann A, Menon S, Netto GJ, Rubin MA, Turajlic S, Raspollini MR, Tickoo SK
Histopathology 2022 Oct;81(4):459-466. Epub 2022 Jul 1 doi: 10.1111/his.14675. PMID: 35502823Free PMC Article
Relationship between the changes of positivity rate of HER2 expression and the diameter of invasive lesions in early breast cancer and its clinical significance.
Han D, Shen R, Yue M, Zhao M, Yu Y, Yao J, Liu Y
Pathol Res Pract 2022 May;233:153877. Epub 2022 Apr 1 doi: 10.1016/j.prp.2022.153877. PMID: 35398619
Molecular alterations of neuroendocrine tumours of the lung.
Rossi G, Bertero L, Marchiò C, Papotti M
Histopathology 2018 Jan;72(1):142-152. doi: 10.1111/his.13394. PMID: 29239031
What clinicians are asking pathologists when dealing with lung neuroendocrine neoplasms?
Pelosi G, Fabbri A, Cossa M, Sonzogni A, Valeri B, Righi L, Papotti M
Semin Diagn Pathol 2015 Nov;32(6):469-79. Epub 2015 Oct 22 doi: 10.1053/j.semdp.2015.10.009. PMID: 26561395
Management and prognosis of endometrioid borderline tumors of the ovary.
Uzan C, Berretta R, Rolla M, Gouy S, Fauvet R, Darai E, Duvillard P, Morice P
Surg Oncol 2012 Sep;21(3):178-84. Epub 2012 Mar 13 doi: 10.1016/j.suronc.2012.02.002. PMID: 22418038

Clinical prediction guides

Supervised machine learning enables non-invasive lesion characterization in primary prostate cancer with [(68)Ga]Ga-PSMA-11 PET/MRI.
Papp L, Spielvogel CP, Grubmüller B, Grahovac M, Krajnc D, Ecsedi B, Sareshgi RAM, Mohamad D, Hamboeck M, Rausch I, Mitterhauser M, Wadsak W, Haug AR, Kenner L, Mazal P, Susani M, Hartenbach S, Baltzer P, Helbich TH, Kramer G, Shariat SF, Beyer T, Hartenbach M, Hacker M
Eur J Nucl Med Mol Imaging 2021 Jun;48(6):1795-1805. Epub 2020 Dec 19 doi: 10.1007/s00259-020-05140-y. PMID: 33341915Free PMC Article
PD-L1 expression in gastroesophageal dysplastic lesions.
Fassan M, Brignola S, Pennelli G, Alberti G, Angerilli V, Bressan A, Pellino A, Lanza C, Salmaso R, Lonardi S, Pucciarelli S, Spolverato G, Scarpa M, Realdon S, Farinati F, Luchini C, Rugge M, Loupakis F
Virchows Arch 2020 Jul;477(1):151-156. Epub 2019 Nov 14 doi: 10.1007/s00428-019-02693-8. PMID: 31724072
Molecular alterations of neuroendocrine tumours of the lung.
Rossi G, Bertero L, Marchiò C, Papotti M
Histopathology 2018 Jan;72(1):142-152. doi: 10.1111/his.13394. PMID: 29239031
What clinicians are asking pathologists when dealing with lung neuroendocrine neoplasms?
Pelosi G, Fabbri A, Cossa M, Sonzogni A, Valeri B, Righi L, Papotti M
Semin Diagn Pathol 2015 Nov;32(6):469-79. Epub 2015 Oct 22 doi: 10.1053/j.semdp.2015.10.009. PMID: 26561395
Role of the micro-environment in Barrett's carcinogenesis.
Lao-Sirieix P, Fitzgerald RC
Biochem Soc Trans 2010 Apr;38(2):327-30. doi: 10.1042/BST0380327. PMID: 20298177

Recent systematic reviews

Underestimation Rate in the Percutaneous Diagnosis of Radial Scar/Complex Sclerosing Lesion of the Breast: Systematic Review.
Zanon ABB, Maesaka JY, Chequin BB, Santos AGS, Baracat EC, Filassi JR
Rev Bras Ginecol Obstet 2022 Jan;44(1):67-73. Epub 2022 Jan 29 doi: 10.1055/s-0041-1741409. PMID: 35092961Free PMC Article
Post-operative radiotherapy for ductal carcinoma in situ of the breast.
Goodwin A, Parker S, Ghersi D, Wilcken N
Cochrane Database Syst Rev 2013 Nov 21;(11):CD000563. doi: 10.1002/14651858.CD000563.pub7. PMID: 24259251
Post-operative radiotherapy for ductal carcinoma in situ of the breast.
Goodwin A, Parker S, Ghersi D, Wilcken N
Cochrane Database Syst Rev 2009 Oct 7;(4):CD000563. doi: 10.1002/14651858.CD000563.pub6. PMID: 19821272
Post-operative radiotherapy for ductal carcinoma in situ of the breast.
Goodwin A, Parker S, Ghersi D, Wilcken N
Cochrane Database Syst Rev 2009 Jul 8;(3):CD000563. doi: 10.1002/14651858.CD000563.pub5. PMID: 19588320
Post-operative radiotherapy for ductal carcinoma in situ of the breast.
Goodwin A, Parker S, Ghersi D, Wilcken N
Cochrane Database Syst Rev 2009 Jan 21;(1):CD000563. doi: 10.1002/14651858.CD000563.pub4. PMID: 19160183

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