U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Leuteoma of Pregnancy

MedGen UID:
274668
•Concept ID:
C1517842
•
Disease or Syndrome

Definition

A non-neoplastic and self-limited condition that occurs during pregnancy. It is characterized by proliferation of luteinized stromal cells that replace the normal ovarian stromal cells. It is usually manifested with bilateral multinodular ovarian masses. Treatment is not required. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLeuteoma of Pregnancy

Professional guidelines

PubMed

Practice Bulletin No. 171: Management of Preterm Labor.
American College of Obstetricians and Gynecologists’ Committee on Practice Bulletins—Obstetrics
Obstet Gynecol 2016 Oct;128(4):e155-64. doi: 10.1097/AOG.0000000000001711. PMID: 27661654
Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline.
Bornstein SR, Allolio B, Arlt W, Barthel A, Don-Wauchope A, Hammer GD, Husebye ES, Merke DP, Murad MH, Stratakis CA, Torpy DJ
J Clin Endocrinol Metab 2016 Feb;101(2):364-89. Epub 2016 Jan 13 doi: 10.1210/jc.2015-1710. PMID: 26760044Free PMC Article
Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline.
Melmed S, Casanueva FF, Hoffman AR, Kleinberg DL, Montori VM, Schlechte JA, Wass JA; Endocrine Society
J Clin Endocrinol Metab 2011 Feb;96(2):273-88. doi: 10.1210/jc.2010-1692. PMID: 21296991

Recent clinical studies

Etiology

The pathophysiological role of estrogens in the initial stages of pregnancy: molecular mechanisms and clinical implications for pregnancy outcome from the periconceptional period to end of the first trimester.
Parisi F, Fenizia C, Introini A, Zavatta A, Scaccabarozzi C, Biasin M, Savasi V
Hum Reprod Update 2023 Nov 2;29(6):699-720. doi: 10.1093/humupd/dmad016. PMID: 37353909Free PMC Article
Monochorionic monoamniotic twin pregnancies.
Van Mieghem T, Abbasi N, Shinar S, Keunen J, Seaward G, Windrim R, Ryan G
Am J Obstet Gynecol MFM 2022 Mar;4(2S):100520. Epub 2021 Oct 30 doi: 10.1016/j.ajogmf.2021.100520. PMID: 34728404
Controversies in the management of twin pregnancy.
Khalil A, Liu B
Ultrasound Obstet Gynecol 2021 Jun;57(6):888-902. Epub 2021 May 21 doi: 10.1002/uog.22181. PMID: 32799348
Pregnancy of unknown location: Evaluation and management.
Carusi D
Semin Perinatol 2019 Mar;43(2):95-100. Epub 2018 Dec 20 doi: 10.1053/j.semperi.2018.12.006. PMID: 30606496
High-Risk Pregnancy.
Holness N
Nurs Clin North Am 2018 Jun;53(2):241-251. Epub 2018 Apr 7 doi: 10.1016/j.cnur.2018.01.010. PMID: 29779516

Diagnosis

Screening and diagnosis of chromosomal abnormalities in twin pregnancy.
D'Antonio F, Khalil A
Best Pract Res Clin Obstet Gynaecol 2022 Nov;84:229-239. Epub 2022 Oct 18 doi: 10.1016/j.bpobgyn.2022.10.001. PMID: 36335006
Monochorionic monoamniotic twin pregnancies.
Van Mieghem T, Abbasi N, Shinar S, Keunen J, Seaward G, Windrim R, Ryan G
Am J Obstet Gynecol MFM 2022 Mar;4(2S):100520. Epub 2021 Oct 30 doi: 10.1016/j.ajogmf.2021.100520. PMID: 34728404
Controversies in the management of twin pregnancy.
Khalil A, Liu B
Ultrasound Obstet Gynecol 2021 Jun;57(6):888-902. Epub 2021 May 21 doi: 10.1002/uog.22181. PMID: 32799348
Pregnancy of unknown location: Evaluation and management.
Carusi D
Semin Perinatol 2019 Mar;43(2):95-100. Epub 2018 Dec 20 doi: 10.1053/j.semperi.2018.12.006. PMID: 30606496
Fetal reduction.
Evans MI, Britt DW
Semin Perinatol 2005 Oct;29(5):321-9. doi: 10.1053/j.semperi.2005.10.004. PMID: 16360491

Therapy

Factors Influencing Contraceptive Choice During the Postpartum Period: A Qualitative Systematic Review.
Robinet L, Jeffredo A, Clesse C
J Midwifery Womens Health 2023 Mar;68(2):265-286. Epub 2023 Mar 10 doi: 10.1111/jmwh.13471. PMID: 36899472
Antispasmodics for labour.
Rohwer AC, Khondowe O, Young T
Cochrane Database Syst Rev 2012 Aug 15;(8):CD009243. doi: 10.1002/14651858.CD009243.pub2. PMID: 22895986
Are you "tilting at windmills" or undertaking a valid clinical trial?
Steeves JD, Zariffa J, Kramer JL
Yonsei Med J 2011 Sep;52(5):701-16. doi: 10.3349/ymj.2011.52.5.701. PMID: 21786433Free PMC Article
Acupuncture for induction of labour.
Smith CA, Crowther CA
Cochrane Database Syst Rev 2004;(1):CD002962. doi: 10.1002/14651858.CD002962.pub2. PMID: 14973999
Recurrent spontaneous abortion.
McIntyre JA, Coulam CB, Faulk WP
Am J Reprod Immunol 1989 Nov-Dec;21(3-4):100-4. doi: 10.1111/j.1600-0897.1989.tb01011.x. PMID: 2534830

Prognosis

Healthy Timing and Spacing of Pregnancy: Reducing Mortality Among Women and Their Children.
Starbird E, Crawford K
Glob Health Sci Pract 2019 Aug 22;7(Suppl 2):S211-S214. Epub 2019 Aug 27 doi: 10.9745/GHSP-D-19-00262. PMID: 31455618Free PMC Article
Pregnancy and Cardiac Disease.
Roos-Hesselink JW, Stein JI
Rev Esp Cardiol (Engl Ed) 2017 Feb;70(2):78-80. Epub 2016 Sep 16 doi: 10.1016/j.rec.2016.08.002. PMID: 27650860
Predictors of Pregnancy Outcomes in Patients With Lupus: A Cohort Study.
Buyon JP, Kim MY, Guerra MM, Laskin CA, Petri M, Lockshin MD, Sammaritano L, Branch DW, Porter TF, Sawitzke A, Merrill JT, Stephenson MD, Cohn E, Garabet L, Salmon JE
Ann Intern Med 2015 Aug 4;163(3):153-63. doi: 10.7326/M14-2235. PMID: 26098843Free PMC Article
Epidemiology of pre-eclampsia and the other hypertensive disorders of pregnancy.
Hutcheon JA, Lisonkova S, Joseph KS
Best Pract Res Clin Obstet Gynaecol 2011 Aug;25(4):391-403. Epub 2011 Feb 18 doi: 10.1016/j.bpobgyn.2011.01.006. PMID: 21333604
Planned caesarean section versus planned vaginal birth for breech presentation at term: a randomised multicentre trial. Term Breech Trial Collaborative Group.
Hannah ME, Hannah WJ, Hewson SA, Hodnett ED, Saigal S, Willan AR
Lancet 2000 Oct 21;356(9239):1375-83. doi: 10.1016/s0140-6736(00)02840-3. PMID: 11052579

Clinical prediction guides

Role of umbilicocerebral and cerebroplacental ratios in prediction of perinatal outcome in FGR pregnancies.
Coenen H, Braun J, Köster H, Möllers M, Schmitz R, Steinhard J, Oelmeier K
Arch Gynecol Obstet 2022 Jun;305(6):1383-1392. Epub 2021 Oct 2 doi: 10.1007/s00404-021-06268-4. PMID: 34599678Free PMC Article
The prediction of preterm delivery: What is new?
Suff N, Story L, Shennan A
Semin Fetal Neonatal Med 2019 Feb;24(1):27-32. Epub 2018 Sep 28 doi: 10.1016/j.siny.2018.09.006. PMID: 30337215
The clinical implications of placental diagnoses.
Redline RW
Semin Perinatol 2015 Feb;39(1):2-8. Epub 2014 Nov 13 doi: 10.1053/j.semperi.2014.10.002. PMID: 25455619
Diagnosing miscarriage.
Bottomley C, Bourne T
Best Pract Res Clin Obstet Gynaecol 2009 Aug;23(4):463-77. Epub 2009 Jun 6 doi: 10.1016/j.bpobgyn.2009.02.004. PMID: 19502113
The nonstress test.
Keegan KA Jr
Clin Obstet Gynecol 1987 Dec;30(4):921-35. doi: 10.1097/00003081-198712000-00016. PMID: 3319323

Recent systematic reviews

Idiopathic polyhydramnios and pregnancy outcome: systematic review and meta-analysis.
Pagan M, Magann EF, Rabie N, Steelman SC, Hu Z, Ounpraseuth S
Ultrasound Obstet Gynecol 2023 Mar;61(3):302-309. Epub 2023 Feb 6 doi: 10.1002/uog.24973. PMID: 35723677
A Systematic Review to Compare Adverse Pregnancy Outcomes in Women with Pregestational Diabetes and Gestational Diabetes.
Malaza N, Masete M, Adam S, Dias S, Nyawo T, Pheiffer C
Int J Environ Res Public Health 2022 Aug 31;19(17) doi: 10.3390/ijerph191710846. PMID: 36078559Free PMC Article
Global Prevalence of Anemia in Pregnant Women: A Comprehensive Systematic Review and Meta-Analysis.
Karami M, Chaleshgar M, Salari N, Akbari H, Mohammadi M
Matern Child Health J 2022 Jul;26(7):1473-1487. Epub 2022 May 24 doi: 10.1007/s10995-022-03450-1. PMID: 35608810
Management of anorexia nervosa in pregnancy: a systematic and state-of-the-art review.
Galbally M, Himmerich H, Senaratne S, Fitzgerald P, Frost J, Woods N, Dickinson JE
Lancet Psychiatry 2022 May;9(5):402-412. Epub 2022 Mar 24 doi: 10.1016/S2215-0366(22)00031-1. PMID: 35339207
Radiofrequency Ablation of Uterine Myomas and Pregnancy Outcomes: An Updated Review of the Literature.
Polin M, Hur HC
J Minim Invasive Gynecol 2022 Jun;29(6):709-715. Epub 2022 Feb 2 doi: 10.1016/j.jmig.2022.01.015. PMID: 35123041

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...