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Vulvar Blue Nevus

MedGen UID:
276990
•Concept ID:
C1520074
•
Neoplastic Process

Definition

A benign nevus that arises from the vulva and is characterized by the presence of heavily pigmented dendritic melanocytes exclusively in the dermis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVulvar Blue Nevus

Recent clinical studies

Etiology

Pigmented vulvar macules as a presenting feature of the Carney complex.
Pandolfino TL, Cotell S, Katta R
Int J Dermatol 2001 Nov;40(11):728-30. doi: 10.1046/j.1365-4362.2001.01281-5.x. PMID: 11737445

Diagnosis

A successfully treated malignant melanoma arising in a large congenital vulvar blue nevus.
Lin W, Song P, Ran X, Li R, Jiang X
Dermatol Ther 2020 Nov;33(6):e13821. Epub 2020 Jul 13 doi: 10.1111/dth.13821. PMID: 32531081
Reflectance confocal microscopy for the diagnosis of vulvar naevi: six cases.
Cinotti E, Couzan C, Perrot JL, Labeille B, Bahadoran P, Puig S, Wantz M, Vicente-Villa A, Habougit C, Butori C, Cambazard F
J Eur Acad Dermatol Venereol 2016 Jan;30(1):30-5. Epub 2014 Dec 29 doi: 10.1111/jdv.12924. PMID: 25546495
Dermoscopic and clinical features of pigmented skin lesions of the genital area.
Cengiz FP, Emiroglu N, Wellenhof RH
An Bras Dermatol 2015 Mar-Apr;90(2):178-83. doi: 10.1590/abd1806-4841.20153294. PMID: 25830986Free PMC Article
Features of pigmented vulval lesions on dermoscopy.
Ronger-Savle S, Julien V, Duru G, Raudrant D, Dalle S, Thomas L
Br J Dermatol 2011 Jan;164(1):54-61. Epub 2010 Nov 12 doi: 10.1111/j.1365-2133.2010.10043.x. PMID: 20846309
Melanocytic lesions of the genital area with attention given to atypical genital nevi.
Ribé A
J Cutan Pathol 2008 Nov;35 Suppl 2:24-7. doi: 10.1111/j.1600-0560.2008.01150.x. PMID: 18976416

Prognosis

Melanocytic lesions of the genital area with attention given to atypical genital nevi.
Ribé A
J Cutan Pathol 2008 Nov;35 Suppl 2:24-7. doi: 10.1111/j.1600-0560.2008.01150.x. PMID: 18976416
Pigmented vulvar macules as a presenting feature of the Carney complex.
Pandolfino TL, Cotell S, Katta R
Int J Dermatol 2001 Nov;40(11):728-30. doi: 10.1046/j.1365-4362.2001.01281-5.x. PMID: 11737445

Clinical prediction guides

A successfully treated malignant melanoma arising in a large congenital vulvar blue nevus.
Lin W, Song P, Ran X, Li R, Jiang X
Dermatol Ther 2020 Nov;33(6):e13821. Epub 2020 Jul 13 doi: 10.1111/dth.13821. PMID: 32531081
Reflectance confocal microscopy for the diagnosis of vulvar naevi: six cases.
Cinotti E, Couzan C, Perrot JL, Labeille B, Bahadoran P, Puig S, Wantz M, Vicente-Villa A, Habougit C, Butori C, Cambazard F
J Eur Acad Dermatol Venereol 2016 Jan;30(1):30-5. Epub 2014 Dec 29 doi: 10.1111/jdv.12924. PMID: 25546495
Dermoscopic and clinical features of pigmented skin lesions of the genital area.
Cengiz FP, Emiroglu N, Wellenhof RH
An Bras Dermatol 2015 Mar-Apr;90(2):178-83. doi: 10.1590/abd1806-4841.20153294. PMID: 25830986Free PMC Article
Features of pigmented vulval lesions on dermoscopy.
Ronger-Savle S, Julien V, Duru G, Raudrant D, Dalle S, Thomas L
Br J Dermatol 2011 Jan;164(1):54-61. Epub 2010 Nov 12 doi: 10.1111/j.1365-2133.2010.10043.x. PMID: 20846309
Melanocytic lesions of the genital area with attention given to atypical genital nevi.
Ribé A
J Cutan Pathol 2008 Nov;35 Suppl 2:24-7. doi: 10.1111/j.1600-0560.2008.01150.x. PMID: 18976416

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