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Parotid gland acinic cell carcinoma

MedGen UID:
277501
•Concept ID:
C1335353
•
Neoplastic Process
Synonyms: Acinic Cell Carcinoma of Parotid; acinic cell carcinoma of parotid; Acinic Cell Carcinoma of Parotid Gland; acinic cell carcinoma of parotid gland; Acinic Cell Carcinoma of the Parotid; acinic cell carcinoma of the parotid; Acinic Cell Carcinoma of the Parotid Gland; acinic cell carcinoma of the parotid gland; Parotid Acinic Cell Carcinoma; parotid acinic cell carcinoma; parotid gland acinar cell carcinoma; Parotid Gland Acinic Cell Carcinoma; parotid gland acinic cell carcinoma
 
Monarch Initiative: MONDO:0006355

Definition

An adenocarcinoma with serous acinar cell differentiation that arises from the parotid gland. Patients usually present with a slow growing mass in the parotid area. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVParotid gland acinic cell carcinoma

Professional guidelines

PubMed

Pediatric primary salivary gland tumors.
Jesberg P, Monzon A, Gitomer SA, Herrmann BW
Am J Otolaryngol 2023 Sep-Oct;44(5):103948. Epub 2023 Jun 8 doi: 10.1016/j.amjoto.2023.103948. PMID: 37352681
Investigation of Sonographic Criteria for Reliable Identification of T1-T2 Low-Grade Malignant Tumors of the Parotid Gland.
Berner F, Koch M, Müller SK, Schapher M, Grundtner P, Iro H, Mantsopoulos K
Ultrasound Med Biol 2021 Mar;47(3):471-477. Epub 2020 Dec 10 doi: 10.1016/j.ultrasmedbio.2020.11.010. PMID: 33309444
Acinic cell carcinoma of the parotid gland: from pathogenesis to management: a literature review.
Cavaliere M, De Luca P, Scarpa A, Savignano L, Cassandro C, Cassandro E, Iemma M
Eur Arch Otorhinolaryngol 2020 Oct;277(10):2673-2679. Epub 2020 May 4 doi: 10.1007/s00405-020-05998-6. PMID: 32367151

Recent clinical studies

Etiology

Fine needle aspiration of salivary gland carcinomas with high-grade transformation: A multi-institutional study of 22 cases and review of the literature.
Nakaguro M, Faquin WC, Baloch ZW, Cantley RL, Compton ML, Ely KA, Holmes BJ, Hu R, Kerr DA, Montone KT, Nishino M, Pantanowitz L, Rossi ED, Sadow PM
Cancer Cytopathol 2021 Apr;129(4):318-325. Epub 2020 Nov 19 doi: 10.1002/cncy.22388. PMID: 33211402Free PMC Article
Analysis of acinic cell carcinoma of the parotid gland - 15 years experience.
Lin WN, Huang HC, Wu CC, Liao CT, Chen IH, Kan CJ, Huang SF
Acta Otolaryngol 2010 Dec;130(12):1406-10. Epub 2010 Sep 2 doi: 10.3109/00016481003796801. PMID: 20809887
Familial occurrence of acinic cell carcinoma of the parotid gland.
Depowski PL, Setzen G, Chui A, Koltai PJ, Dollar J, Ross JS
Arch Pathol Lab Med 1999 Nov;123(11):1118-20. doi: 10.5858/1999-123-1118-FOOACC. PMID: 10539921

Diagnosis

Fine needle aspiration of salivary gland carcinomas with high-grade transformation: A multi-institutional study of 22 cases and review of the literature.
Nakaguro M, Faquin WC, Baloch ZW, Cantley RL, Compton ML, Ely KA, Holmes BJ, Hu R, Kerr DA, Montone KT, Nishino M, Pantanowitz L, Rossi ED, Sadow PM
Cancer Cytopathol 2021 Apr;129(4):318-325. Epub 2020 Nov 19 doi: 10.1002/cncy.22388. PMID: 33211402Free PMC Article
Acinic Cell Carcinoma of the Parotid Gland in Children and Adolescents.
Ash S, Yaniv I, Feinmesser R, Konen O, Feinmesser M
J Pediatr Hematol Oncol 2018 Mar;40(2):99-103. doi: 10.1097/MPH.0000000000000994. PMID: 29240035
Analysis of acinic cell carcinoma of the parotid gland - 15 years experience.
Lin WN, Huang HC, Wu CC, Liao CT, Chen IH, Kan CJ, Huang SF
Acta Otolaryngol 2010 Dec;130(12):1406-10. Epub 2010 Sep 2 doi: 10.3109/00016481003796801. PMID: 20809887

Therapy

Analysis of acinic cell carcinoma of the parotid gland - 15 years experience.
Lin WN, Huang HC, Wu CC, Liao CT, Chen IH, Kan CJ, Huang SF
Acta Otolaryngol 2010 Dec;130(12):1406-10. Epub 2010 Sep 2 doi: 10.3109/00016481003796801. PMID: 20809887

Prognosis

Fine needle aspiration of salivary gland carcinomas with high-grade transformation: A multi-institutional study of 22 cases and review of the literature.
Nakaguro M, Faquin WC, Baloch ZW, Cantley RL, Compton ML, Ely KA, Holmes BJ, Hu R, Kerr DA, Montone KT, Nishino M, Pantanowitz L, Rossi ED, Sadow PM
Cancer Cytopathol 2021 Apr;129(4):318-325. Epub 2020 Nov 19 doi: 10.1002/cncy.22388. PMID: 33211402Free PMC Article
Acinic Cell Carcinoma of the Parotid Gland in Children and Adolescents.
Ash S, Yaniv I, Feinmesser R, Konen O, Feinmesser M
J Pediatr Hematol Oncol 2018 Mar;40(2):99-103. doi: 10.1097/MPH.0000000000000994. PMID: 29240035
Analysis of acinic cell carcinoma of the parotid gland - 15 years experience.
Lin WN, Huang HC, Wu CC, Liao CT, Chen IH, Kan CJ, Huang SF
Acta Otolaryngol 2010 Dec;130(12):1406-10. Epub 2010 Sep 2 doi: 10.3109/00016481003796801. PMID: 20809887

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