U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Bovine Respiratory Disease Complex

MedGen UID:
304277
•Concept ID:
C1449809
•
Disease or Syndrome

Definition

A multifactorial disease of CATTLE resulting from complex interactions between environmental factors, host factors, and pathogens. The environmental factors act as stressors adversely affecting the IMMUNE SYSTEM and other host defenses and enhancing transmission of infecting agents. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBovine Respiratory Disease Complex

Recent clinical studies

Etiology

Feeding selenium-biofortified alfalfa hay during the preconditioning period improves growth, carcass weight, and nasal microbial diversity of beef calves.
Hall JA, Isaiah A, Bobe G, Estill CT, Bishop-Stewart JK, Davis TZ, Suchodolski JS, Pirelli GJ
PLoS One 2020;15(12):e0242771. Epub 2020 Dec 1 doi: 10.1371/journal.pone.0242771. PMID: 33259499Free PMC Article
Use of Antimicrobial Metaphylaxis for the Control of Bovine Respiratory Disease in High-Risk Cattle.
Ives SE, Richeson JT
Vet Clin North Am Food Anim Pract 2015 Nov;31(3):341-50, v. Epub 2015 Jul 28 doi: 10.1016/j.cvfa.2015.05.008. PMID: 26227871
Evaluating the cost implications of a radio frequency identification feeding system for early detection of bovine respiratory disease in feedlot cattle.
Wolfger B, Manns BJ, Barkema HW, Schwartzkopf-Genswein KS, Dorin C, Orsel K
Prev Vet Med 2015 Mar 1;118(4):285-92. Epub 2014 Dec 11 doi: 10.1016/j.prevetmed.2014.12.001. PMID: 25534973
Natural human interferon-alpha administered orally as a treatment of bovine respiratory disease complex.
Cummins JM, Guthrie D, Hutcheson DP, Krakowka S, Rosenquist BD
J Interferon Cytokine Res 1999 Aug;19(8):907-10. doi: 10.1089/107999099313442. PMID: 10476937

Diagnosis

Behavior assessment and applications for BRD diagnosis: beef.
Richeson JT
Anim Health Res Rev 2020 Dec;21(2):192-195. doi: 10.1017/S1466252320000249. PMID: 33682665
Evaluation of inter-observer agreement when using a clinical respiratory scoring system in pre-weaned dairy calves.
Buczinski S, Faure C, Jolivet S, Abdallah A
N Z Vet J 2016 Jul;64(4):243-7. Epub 2016 Mar 2 doi: 10.1080/00480169.2016.1153439. PMID: 26878417
Use of Antimicrobial Metaphylaxis for the Control of Bovine Respiratory Disease in High-Risk Cattle.
Ives SE, Richeson JT
Vet Clin North Am Food Anim Pract 2015 Nov;31(3):341-50, v. Epub 2015 Jul 28 doi: 10.1016/j.cvfa.2015.05.008. PMID: 26227871
Evaluating the cost implications of a radio frequency identification feeding system for early detection of bovine respiratory disease in feedlot cattle.
Wolfger B, Manns BJ, Barkema HW, Schwartzkopf-Genswein KS, Dorin C, Orsel K
Prev Vet Med 2015 Mar 1;118(4):285-92. Epub 2014 Dec 11 doi: 10.1016/j.prevetmed.2014.12.001. PMID: 25534973
Sensitivity comparison for detection of respiratory bovine coronaviruses in nasal samples from feedlot cattle by ELISA and isolation with the G clone of HRT-18 cells.
da Silva MR, O'Reilly KL, Lin X, Stine L, Storz J
J Vet Diagn Invest 1999 Jan;11(1):15-9. doi: 10.1177/104063879901100102. PMID: 9925206

Therapy

Feeding selenium-biofortified alfalfa hay during the preconditioning period improves growth, carcass weight, and nasal microbial diversity of beef calves.
Hall JA, Isaiah A, Bobe G, Estill CT, Bishop-Stewart JK, Davis TZ, Suchodolski JS, Pirelli GJ
PLoS One 2020;15(12):e0242771. Epub 2020 Dec 1 doi: 10.1371/journal.pone.0242771. PMID: 33259499Free PMC Article
Use of Antimicrobial Metaphylaxis for the Control of Bovine Respiratory Disease in High-Risk Cattle.
Ives SE, Richeson JT
Vet Clin North Am Food Anim Pract 2015 Nov;31(3):341-50, v. Epub 2015 Jul 28 doi: 10.1016/j.cvfa.2015.05.008. PMID: 26227871
Natural human interferon-alpha administered orally as a treatment of bovine respiratory disease complex.
Cummins JM, Guthrie D, Hutcheson DP, Krakowka S, Rosenquist BD
J Interferon Cytokine Res 1999 Aug;19(8):907-10. doi: 10.1089/107999099313442. PMID: 10476937

Prognosis

Behavior assessment and applications for BRD diagnosis: beef.
Richeson JT
Anim Health Res Rev 2020 Dec;21(2):192-195. doi: 10.1017/S1466252320000249. PMID: 33682665
Evaluating the cost implications of a radio frequency identification feeding system for early detection of bovine respiratory disease in feedlot cattle.
Wolfger B, Manns BJ, Barkema HW, Schwartzkopf-Genswein KS, Dorin C, Orsel K
Prev Vet Med 2015 Mar 1;118(4):285-92. Epub 2014 Dec 11 doi: 10.1016/j.prevetmed.2014.12.001. PMID: 25534973

Clinical prediction guides

Behavior assessment and applications for BRD diagnosis: beef.
Richeson JT
Anim Health Res Rev 2020 Dec;21(2):192-195. doi: 10.1017/S1466252320000249. PMID: 33682665
Priming Cross-Protective Bovine Viral Diarrhea Virus-Specific Immunity Using Live-Vectored Mosaic Antigens.
Lokhandwala S, Fang X, Waghela SD, Bray J, Njongmeta LM, Herring A, Abdelsalam KW, Chase C, Mwangi W
PLoS One 2017;12(1):e0170425. Epub 2017 Jan 18 doi: 10.1371/journal.pone.0170425. PMID: 28099492Free PMC Article
Parainfluenza Virus 3 Blocks Antiviral Mediators Downstream of the Interferon Lambda Receptor by Modulating Stat1 Phosphorylation.
Eberle KC, McGill JL, Reinhardt TA, Sacco RE
J Virol 2015 Dec 30;90(6):2948-58. doi: 10.1128/JVI.02502-15. PMID: 26719274Free PMC Article
Evaluating the cost implications of a radio frequency identification feeding system for early detection of bovine respiratory disease in feedlot cattle.
Wolfger B, Manns BJ, Barkema HW, Schwartzkopf-Genswein KS, Dorin C, Orsel K
Prev Vet Med 2015 Mar 1;118(4):285-92. Epub 2014 Dec 11 doi: 10.1016/j.prevetmed.2014.12.001. PMID: 25534973
Neonatal calf infection with respiratory syncytial virus: drawing parallels to the disease in human infants.
Sacco RE, McGill JL, Palmer MV, Lippolis JD, Reinhardt TA, Nonnecke BJ
Viruses 2012 Dec;4(12):3731-53. doi: 10.3390/v4123731. PMID: 23342375Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...