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Pleomorphic Hyalinizing Angiectatic Tumor of Soft Parts

MedGen UID:
313593
Concept ID:
C1709569
Neoplastic Process
Synonyms: Early Pleomorphic Hyalinizing Angiectatic Tumor; Pleomorphic hyalinizing angiectatic neoplasm of soft parts; Pleomorphic hyalinizing angiectatic neoplasm of soft tissue; Pleomorphic hyalinizing angiectatic tumor of soft parts; Pleomorphic hyalinizing angiectatic tumor of soft tissue
SNOMED CT: Pleomorphic hyalinizing angiectatic tumor of soft tissue (720487006); Pleomorphic hyalinizing angiectatic tumor of soft parts (720487006); Pleomorphic hyalinizing angiectatic neoplasm of soft tissue (720487006); Pleomorphic hyalinizing angiectatic neoplasm of soft parts (720487006)

Definition

A non-metastasizing soft tissue neoplasm characterized by the presence of a neoplastic stroma containing spindle cells, dilated thin-walled vessels lined by fibrin, and a chronic inflammatory infiltrate. The majority of cases develop in the subcutaneous tissues usually in the lower extremities and present as slow growing masses. Recurrences occur in approximately half of the cases. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPleomorphic Hyalinizing Angiectatic Tumor of Soft Parts

Professional guidelines

PubMed

Rush AJ 3rd, Patel PD, Shemesh S, Subhawong TK, Pretell-Mazzini J
Musculoskelet Surg 2018 Dec;102(3):213-221. Epub 2018 Feb 1 doi: 10.1007/s12306-018-0532-1. PMID: 29392614

Recent clinical studies

Etiology

Rush AJ 3rd, Patel PD, Shemesh S, Subhawong TK, Pretell-Mazzini J
Musculoskelet Surg 2018 Dec;102(3):213-221. Epub 2018 Feb 1 doi: 10.1007/s12306-018-0532-1. PMID: 29392614

Diagnosis

Rush AJ 3rd, Patel PD, Shemesh S, Subhawong TK, Pretell-Mazzini J
Musculoskelet Surg 2018 Dec;102(3):213-221. Epub 2018 Feb 1 doi: 10.1007/s12306-018-0532-1. PMID: 29392614
Gupta N, Kenan S, Kahn LB
Int J Surg Pathol 2018 Feb;26(1):73-77. Epub 2017 Aug 1 doi: 10.1177/1066896917723463. PMID: 28764610
Changchien YC, Bocskai P, Kovács I, Hargitai Z, Kollár S, Török M
Pathol Res Pract 2014 Dec;210(12):1146-51. Epub 2014 May 4 doi: 10.1016/j.prp.2014.04.016. PMID: 24857338
El-Tal AE, Mehregan D
J Cutan Pathol 2006 May;33(5):361-4. doi: 10.1111/j.0303-6987.2006.00416.x. PMID: 16640543
Fujiwara M, Yuba Y, Wada A, Ozawa T, Tanaka T
J Dermatol 2004 May;31(5):419-23. doi: 10.1111/j.1346-8138.2004.tb00696.x. PMID: 15187312

Therapy

Fan C, Lin X, Yang L, Wang E
Int J Clin Exp Pathol 2015;8(9):11804-8. Epub 2015 Sep 1 PMID: 26617930Free PMC Article

Prognosis

Rush AJ 3rd, Patel PD, Shemesh S, Subhawong TK, Pretell-Mazzini J
Musculoskelet Surg 2018 Dec;102(3):213-221. Epub 2018 Feb 1 doi: 10.1007/s12306-018-0532-1. PMID: 29392614
Ke Q, Erbolat, Zhang HY, Bu H, Li S, Shi DN, Yang GH, Chen HJ, Wei B
Chin Med J (Engl) 2007 May 20;120(10):876-81. PMID: 17571460

Clinical prediction guides

Rush AJ 3rd, Patel PD, Shemesh S, Subhawong TK, Pretell-Mazzini J
Musculoskelet Surg 2018 Dec;102(3):213-221. Epub 2018 Feb 1 doi: 10.1007/s12306-018-0532-1. PMID: 29392614
Ke Q, Erbolat, Zhang HY, Bu H, Li S, Shi DN, Yang GH, Chen HJ, Wei B
Chin Med J (Engl) 2007 May 20;120(10):876-81. PMID: 17571460
Matsumoto K, Yamamoto T
Pathol Int 2002 Oct;52(10):664-8. doi: 10.1046/j.1440-1827.2002.01406.x. PMID: 12445140
Fukunaga M, Ushigome S
Pathol Int 1997 Nov;47(11):784-8. doi: 10.1111/j.1440-1827.1997.tb04458.x. PMID: 9413039
Silverman JS, Dana MM
J Cutan Pathol 1997 Jul;24(6):377-83. doi: 10.1111/j.1600-0560.1997.tb00807.x. PMID: 9243366

Recent systematic reviews

Rush AJ 3rd, Patel PD, Shemesh S, Subhawong TK, Pretell-Mazzini J
Musculoskelet Surg 2018 Dec;102(3):213-221. Epub 2018 Feb 1 doi: 10.1007/s12306-018-0532-1. PMID: 29392614

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