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Membranous subvalvular aortic stenosis

MedGen UID:
336467
•Concept ID:
C1848978
•
Finding
HPO: HP:0005174

Definition

Subvalvular stenosis is caused by a diaphragm-like membrane. The stenosis is clinically manifested like any other form of aortic stenosis but is often associated with some aortic insufficiency. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMembranous subvalvular aortic stenosis

Professional guidelines

PubMed

Multilayer Myocardial Mechanics in Genotype-Positive Left Ventricular Hypertrophy-Negative Patients With Hypertrophic Cardiomyopathy.
Williams LK, Misurka J, Ho CY, Chan WX, Agmon Y, Seidman C, Rakowski H, Carasso S
Am J Cardiol 2018 Nov 15;122(10):1754-1760. Epub 2018 Aug 21 doi: 10.1016/j.amjcard.2018.08.008. PMID: 30249441
Medical management of hypertrophic cardiomyopathy.
Naghi JJ, Siegel RJ
Rev Cardiovasc Med 2010 Fall;11(4):202-17. doi: 10.3909/ricm0546. PMID: 21389910
Transaortic resection of the subaortic membrane. Treatment for subvalvular aortic stenosis.
Jacobs JP, Palatianos GM, Cintron JR, Kaiser GA
Chest 1994 Jul;106(1):46-51. doi: 10.1378/chest.106.1.46. PMID: 8020319

Recent clinical studies

Etiology

Aortic regurgitation after surgical relief of subvalvular membranous stenosis. A long-term follow-up study.
Bjørn-Hansen LS, Lund O, Nielsen TT, Kromann-Hansen O, Jensen FT
Scand J Thorac Cardiovasc Surg 1988;22(3):275-9. doi: 10.3109/14017438809106075. PMID: 3227330

Diagnosis

Combined discrete membranous subvalvular aortic stenosis and idiopathic hypertrophic subaortic stenosis. A case report.
Pahlajani DB, Dastur KN, Mody R, Devrall PB
Indian Heart J 1980 Nov-Dec;32(6):386-8. PMID: 7194851
Echocardiographic features of combined hypertrophic and membranous subvalvular aortic stenosis: a case report.
Krueger SK, Hofschire PJ, Forker AD
J Clin Ultrasound 1976 Feb;4(1):31-4. doi: 10.1002/jcu.1870040111. PMID: 814139

Prognosis

Aortic regurgitation after surgical relief of subvalvular membranous stenosis. A long-term follow-up study.
Bjørn-Hansen LS, Lund O, Nielsen TT, Kromann-Hansen O, Jensen FT
Scand J Thorac Cardiovasc Surg 1988;22(3):275-9. doi: 10.3109/14017438809106075. PMID: 3227330

Clinical prediction guides

Aortic regurgitation after surgical relief of subvalvular membranous stenosis. A long-term follow-up study.
Bjørn-Hansen LS, Lund O, Nielsen TT, Kromann-Hansen O, Jensen FT
Scand J Thorac Cardiovasc Surg 1988;22(3):275-9. doi: 10.3109/14017438809106075. PMID: 3227330

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