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Fair Skin

MedGen UID:
347669
•Concept ID:
C1858570
•
Finding
Synonym: Fair skin

Definition

A human skin color characterized by low levels of eumelanin. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFair Skin

Professional guidelines

PubMed

Preferred practice patterns and review on rosacea.
Patel NV, Gupta N, Shetty R
Indian J Ophthalmol 2023 Apr;71(4):1382-1390. doi: 10.4103/IJO.IJO_2983_22. PMID: 37026270Free PMC Article
Basal Cell and Cutaneous Squamous Cell Carcinomas: Diagnosis and Treatment.
Firnhaber JM
Am Fam Physician 2020 Sep 15;102(6):339-346. PMID: 32931212
Nonmelanoma skin cancer associated with Hydroxyurea treatment: Overview of the literature and our own experience.
Cantisani C, Kiss N, Naqeshbandi AF, Tosti G, Tofani S, Cartoni C, Carmosino I, Cantoresi F
Dermatol Ther 2019 Sep;32(5):e13043. Epub 2019 Aug 16 doi: 10.1111/dth.13043. PMID: 31364787

Recent clinical studies

Etiology

Basal Cell and Cutaneous Squamous Cell Carcinomas: Diagnosis and Treatment.
Firnhaber JM
Am Fam Physician 2020 Sep 15;102(6):339-346. PMID: 32931212
Uveal melanoma.
Jager MJ, Shields CL, Cebulla CM, Abdel-Rahman MH, Grossniklaus HE, Stern MH, Carvajal RD, Belfort RN, Jia R, Shields JA, Damato BE
Nat Rev Dis Primers 2020 Apr 9;6(1):24. doi: 10.1038/s41572-020-0158-0. PMID: 32273508
Palmitoylation-dependent activation of MC1R prevents melanomagenesis.
Chen S, Zhu B, Yin C, Liu W, Han C, Chen B, Liu T, Li X, Chen X, Li C, Hu L, Zhou J, Xu ZX, Gao X, Wu X, Goding CR, Cui R
Nature 2017 Sep 21;549(7672):399-403. Epub 2017 Sep 6 doi: 10.1038/nature23887. PMID: 28869973Free PMC Article
Uveal melanoma: relatively rare but deadly cancer.
Kaliki S, Shields CL
Eye (Lond) 2017 Feb;31(2):241-257. Epub 2016 Dec 2 doi: 10.1038/eye.2016.275. PMID: 27911450Free PMC Article
Skin Cancer.
Linares MA, Zakaria A, Nizran P
Prim Care 2015 Dec;42(4):645-59. doi: 10.1016/j.pop.2015.07.006. PMID: 26612377

Diagnosis

Basal Cell and Cutaneous Squamous Cell Carcinomas: Diagnosis and Treatment.
Firnhaber JM
Am Fam Physician 2020 Sep 15;102(6):339-346. PMID: 32931212
Uveal melanoma.
Jager MJ, Shields CL, Cebulla CM, Abdel-Rahman MH, Grossniklaus HE, Stern MH, Carvajal RD, Belfort RN, Jia R, Shields JA, Damato BE
Nat Rev Dis Primers 2020 Apr 9;6(1):24. doi: 10.1038/s41572-020-0158-0. PMID: 32273508
Uveal melanoma: relatively rare but deadly cancer.
Kaliki S, Shields CL
Eye (Lond) 2017 Feb;31(2):241-257. Epub 2016 Dec 2 doi: 10.1038/eye.2016.275. PMID: 27911450Free PMC Article
Skin Cancer.
Linares MA, Zakaria A, Nizran P
Prim Care 2015 Dec;42(4):645-59. doi: 10.1016/j.pop.2015.07.006. PMID: 26612377
Photoaging.
Han A, Chien AL, Kang S
Dermatol Clin 2014 Jul;32(3):291-9, vii. doi: 10.1016/j.det.2014.03.015. PMID: 24891052

Therapy

Rosacea pathogenesis, common triggers, and dietary role: The cause, the trigger, and the positive effects of different foods.
Alia E, Feng H
Clin Dermatol 2022 Mar-Apr;40(2):122-127. Epub 2021 Oct 27 doi: 10.1016/j.clindermatol.2021.10.004. PMID: 34819228
Vitiligo: An Updated Narrative Review.
Leung AKC, Lam JM, Leong KF, Hon KL
Curr Pediatr Rev 2021;17(2):76-91. doi: 10.2174/1573396316666201210125858. PMID: 33302860
Uveal melanoma: relatively rare but deadly cancer.
Kaliki S, Shields CL
Eye (Lond) 2017 Feb;31(2):241-257. Epub 2016 Dec 2 doi: 10.1038/eye.2016.275. PMID: 27911450Free PMC Article
Photoaging.
Han A, Chien AL, Kang S
Dermatol Clin 2014 Jul;32(3):291-9, vii. doi: 10.1016/j.det.2014.03.015. PMID: 24891052
The protective role of melanin against UV damage in human skin.
Brenner M, Hearing VJ
Photochem Photobiol 2008 May-Jun;84(3):539-49. doi: 10.1111/j.1751-1097.2007.00226.x. PMID: 18435612Free PMC Article

Prognosis

Rosacea pathogenesis, common triggers, and dietary role: The cause, the trigger, and the positive effects of different foods.
Alia E, Feng H
Clin Dermatol 2022 Mar-Apr;40(2):122-127. Epub 2021 Oct 27 doi: 10.1016/j.clindermatol.2021.10.004. PMID: 34819228
Vitiligo: An Updated Narrative Review.
Leung AKC, Lam JM, Leong KF, Hon KL
Curr Pediatr Rev 2021;17(2):76-91. doi: 10.2174/1573396316666201210125858. PMID: 33302860
Uveal melanoma.
Jager MJ, Shields CL, Cebulla CM, Abdel-Rahman MH, Grossniklaus HE, Stern MH, Carvajal RD, Belfort RN, Jia R, Shields JA, Damato BE
Nat Rev Dis Primers 2020 Apr 9;6(1):24. doi: 10.1038/s41572-020-0158-0. PMID: 32273508
Uveal melanoma: relatively rare but deadly cancer.
Kaliki S, Shields CL
Eye (Lond) 2017 Feb;31(2):241-257. Epub 2016 Dec 2 doi: 10.1038/eye.2016.275. PMID: 27911450Free PMC Article
Merkel cell carcinoma.
Swann MH, Yoon J
Semin Oncol 2007 Feb;34(1):51-6. doi: 10.1053/j.seminoncol.2006.10.021. PMID: 17270666

Clinical prediction guides

Lentigo maligna: a review.
Karponis D, Stratigos IA, Joshy J, Craig PJ, Mistry K, van Bodegraven B, Venables ZC, Levell NJ
Clin Exp Dermatol 2024 Feb 14;49(3):218-225. doi: 10.1093/ced/llad394. PMID: 37966718
Vitiligo: An Updated Narrative Review.
Leung AKC, Lam JM, Leong KF, Hon KL
Curr Pediatr Rev 2021;17(2):76-91. doi: 10.2174/1573396316666201210125858. PMID: 33302860
"The unfair drive to be fair": Psychosocial aspects and implications of the use of skin lightening agents.
Shivakumar S, Jafferany M
Dermatol Ther 2020 Nov;33(6):e14091. Epub 2020 Aug 24 doi: 10.1111/dth.14091. PMID: 32720427
Nonmelanoma skin cancer associated with Hydroxyurea treatment: Overview of the literature and our own experience.
Cantisani C, Kiss N, Naqeshbandi AF, Tosti G, Tofani S, Cartoni C, Carmosino I, Cantoresi F
Dermatol Ther 2019 Sep;32(5):e13043. Epub 2019 Aug 16 doi: 10.1111/dth.13043. PMID: 31364787
Uveal melanoma: relatively rare but deadly cancer.
Kaliki S, Shields CL
Eye (Lond) 2017 Feb;31(2):241-257. Epub 2016 Dec 2 doi: 10.1038/eye.2016.275. PMID: 27911450Free PMC Article

Recent systematic reviews

Global prevalence of oral pigmentation and its related factors: a systematic review and meta-analysis.
Rotbeh A, Kazeminia M, Kalantari M, Rajati F
J Stomatol Oral Maxillofac Surg 2022 Oct;123(5):e411-e424. Epub 2022 Jan 20 doi: 10.1016/j.jormas.2022.01.009. PMID: 35066171
Ethnic diversity in German dermatology textbooks: Does it exist and is it important? A mini review.
Gregersen DM, Elsner P
J Dtsch Dermatol Ges 2021 Nov;19(11):1582-1589. Epub 2021 Sep 29 doi: 10.1111/ddg.14543. PMID: 34585822
Uveal Melanoma Risk Factors: A Systematic Review of Meta-Analyses.
Nayman T, Bostan C, Logan P, Burnier MN Jr
Curr Eye Res 2017 Aug;42(8):1085-1093. Epub 2017 May 11 doi: 10.1080/02713683.2017.1297997. PMID: 28494168
Incidence and prevalence of non-melanoma skin cancer in Australia: A systematic review.
Perera E, Gnaneswaran N, Staines C, Win AK, Sinclair R
Australas J Dermatol 2015 Nov;56(4):258-67. Epub 2015 Feb 25 doi: 10.1111/ajd.12282. PMID: 25716064
Squamous cell carcinoma of the skin (non-metastatic).
Green AC, McBride P
BMJ Clin Evid 2014 Aug 18;2014 PMID: 25137222Free PMC Article

Supplemental Content

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    Practice guidelines

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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

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