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Dermal Nodule

MedGen UID:
353607
•Concept ID:
C1707685
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDermal Nodule

Professional guidelines

PubMed

Challenges in the diagnosis of neurofibromatosis type 1 (NF1) in young children facilitated by means of revised diagnostic criteria including genetic testing for pathogenic NF1 gene variants.
Kehrer-Sawatzki H, Cooper DN
Hum Genet 2022 Feb;141(2):177-191. Epub 2021 Dec 20 doi: 10.1007/s00439-021-02410-z. PMID: 34928431Free PMC Article
Eosinophilic Dermatoses: Recognition and Management.
Marzano AV, Genovese G
Am J Clin Dermatol 2020 Aug;21(4):525-539. doi: 10.1007/s40257-020-00520-4. PMID: 32394361
The role of hyaluronidase in the treatment of complications from hyaluronic acid dermal fillers.
Cavallini M, Gazzola R, Metalla M, Vaienti L
Aesthet Surg J 2013 Nov 1;33(8):1167-74. Epub 2013 Nov 6 doi: 10.1177/1090820X13511970. PMID: 24197934

Recent clinical studies

Etiology

Spiradenoma With Adenoid Cystic Carcinoma-Like Features.
Hopkins C, Moyer A, Huttenbach YT
Am J Dermatopathol 2020 Jun;42(6):442-445. doi: 10.1097/DAD.0000000000001594. PMID: 31855584
Histological features and outcome of inverted type-A melanocytic nevi.
Dadras SS, Lu J, Zembowicz A, Flotte TJ, Mihm MC
J Cutan Pathol 2018 Apr;45(4):254-262. Epub 2018 Feb 13 doi: 10.1111/cup.13106. PMID: 29341232
Benign melanocytic lesions mimicking melanomas.
Cook MG
Pathology 2004 Oct;36(5):414-8. doi: 10.1080/00313020412331283842. PMID: 15370110
Cellular nodules in congenital pattern nevi.
Xu X, Bellucci KS, Elenitsas R, Elder DE
J Cutan Pathol 2004 Feb;31(2):153-9. doi: 10.1111/j.0303-6987.2004.00156.x. PMID: 14690460
Atypical cutaneous fibrous histiocytoma.
Leyva WH, Santa Cruz DJ
Am J Dermatopathol 1986 Dec;8(6):467-71. doi: 10.1097/00000372-198612000-00003. PMID: 3028197

Diagnosis

Relation Between Atypical Fibroxanthoma and Pleomorphic Dermal Sarcoma: Histopathologic Features and Review of the Literature.
Iglesias-Pena N, Martínez-Campayo N, López-Solache L
Actas Dermosifiliogr (Engl Ed) 2021 May;112(5):392-405. Epub 2020 Dec 7 doi: 10.1016/j.ad.2020.11.018. PMID: 33301761
Cutaneous metastases: A great imitator.
Jaros J, Hunt S, Mose E, Lai O, Tsoukas M
Clin Dermatol 2020 Mar-Apr;38(2):216-222. Epub 2019 Oct 25 doi: 10.1016/j.clindermatol.2019.10.004. PMID: 32513401
Trichogerminoma.
Tellechea O, Reis JP
Am J Dermatopathol 2009 Jul;31(5):480-3. doi: 10.1097/DAD.0b013e31818ffcc3. PMID: 19542926
Benign melanocytic lesions mimicking melanomas.
Cook MG
Pathology 2004 Oct;36(5):414-8. doi: 10.1080/00313020412331283842. PMID: 15370110
Giant dermatofibroma. A little-known clinical variant of dermatofibroma.
Requena L, Fariña MC, Fuente C, Piqué E, Olivares M, Martín L, Sánchez Yus E
J Am Acad Dermatol 1994 May;30(5 Pt 1):714-8. PMID: 8176009

Therapy

Prolonged Response to Pembrolizumab in Spindle Cell Squamous Cell Carcinoma Metastatic to the Central Nervous System.
Liu Y, Fitzgerald B, Perry E, Pathak A, Chao HH
J Investig Med High Impact Case Rep 2019 Jan-Dec;7:2324709619850216. doi: 10.1177/2324709619850216. PMID: 31132886Free PMC Article
Onchocerciasis (river blindness).
Borup LH, Peters JS, Sartori CR
Cutis 2003 Oct;72(4):297-302; quiz 296. PMID: 14604081
The development and course of test reactions to gold sodium thiosulfate.
Bruze M, Hedman H, Björkner B, Möller H
Contact Dermatitis 1995 Dec;33(6):386-91. doi: 10.1111/j.1600-0536.1995.tb02072.x. PMID: 8706395

Prognosis

Cutaneous metastases: A great imitator.
Jaros J, Hunt S, Mose E, Lai O, Tsoukas M
Clin Dermatol 2020 Mar-Apr;38(2):216-222. Epub 2019 Oct 25 doi: 10.1016/j.clindermatol.2019.10.004. PMID: 32513401
Cutaneous leiomyosarcoma - Case report.
Ciurea ME, Georgescu CV, Radu CC, Georgescu CC, Stoica LE
J Med Life 2014 Jun 15;7(2):270-3. Epub 2014 Jun 25 PMID: 25408738Free PMC Article
Trichogerminoma, a rare cutaneous follicular neoplasm with indolent clinical course: report of two cases and review of literature.
Chen LL, Hu JT, Li Y
Diagn Pathol 2013 Dec 19;8:210. doi: 10.1186/1746-1596-8-210. PMID: 24354761Free PMC Article
Cellular nodules in congenital pattern nevi.
Xu X, Bellucci KS, Elenitsas R, Elder DE
J Cutan Pathol 2004 Feb;31(2):153-9. doi: 10.1111/j.0303-6987.2004.00156.x. PMID: 14690460
Atypical cutaneous fibrous histiocytoma.
Leyva WH, Santa Cruz DJ
Am J Dermatopathol 1986 Dec;8(6):467-71. doi: 10.1097/00000372-198612000-00003. PMID: 3028197

Clinical prediction guides

Desmoplastic melanoma: a challenge for the oncologist.
Manfredini M, Pellacani G, Losi L, Maccaferri M, Tomasi A, Ponti G
Future Oncol 2017 Feb;13(4):337-345. Epub 2016 Oct 12 doi: 10.2217/fon-2016-0334. PMID: 27728982
Clinicopathological study of 47 cases of sebaceoma.
Bourlond F, Velter C, Cribier B
Ann Dermatol Venereol 2016 Dec;143(12):814-824. Epub 2016 Nov 9 doi: 10.1016/j.annder.2016.06.013. PMID: 27836252
YAP immunoreactivity is directly related to pilomatrixoma size and proliferation rate.
Cappellesso R, Bellan A, Saraggi D, Salmaso R, Ventura L, Fassina A
Arch Dermatol Res 2015 May;307(4):379-83. Epub 2014 Dec 17 doi: 10.1007/s00403-014-1530-2. PMID: 25516090
Granuloma Annulare Mimicking Sarcoidosis: Report of Patient With Localized Granuloma Annulare Whose Skin Lesions Show 3 Clinical Morphologies and 2 Histology Patterns.
Cohen PR, Carlos CA
Am J Dermatopathol 2015 Jul;37(7):547-50. doi: 10.1097/DAD.0000000000000125. PMID: 25140662
Dermal squamo-melanocytic tumor: a unique biphenotypic neoplasm of uncertain biological potential.
Pool SE, Manieei F, Clark WH Jr, Harrist TJ
Hum Pathol 1999 May;30(5):525-9. doi: 10.1016/s0046-8177(99)90195-8. PMID: 10333221

Recent systematic reviews

Pediatric cellular neurothekeoma: Seven cases and systematic review of the literature.
Murphrey M, Huy Nguyen A, White KP, Krol A, Bernert R, Yarbrough K
Pediatr Dermatol 2020 Mar;37(2):320-325. Epub 2020 Jan 12 doi: 10.1111/pde.14043. PMID: 31930561

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