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Epicardium cancer

MedGen UID:
388560
•Concept ID:
C2607932
•
Neoplastic Process
Synonyms: cancer of epicardium; epicardium cancer; Malignant Epicardial Neoplasm; malignant epicardial neoplasm; Malignant Epicardial Tumor; malignant epicardial tumor; malignant epicardial tumour; malignant epicardium neoplasm; Malignant Neoplasm of Epicardium; malignant neoplasm of epicardium; Malignant Neoplasm of the Epicardium; malignant neoplasm of the epicardium; Malignant Tumor of Epicardium; malignant tumor of epicardium; Malignant Tumor of the Epicardium; malignant tumor of the epicardium; malignant tumour of epicardium; malignant tumour of the epicardium
 
Monarch Initiative: MONDO:0003104

Definition

A malignant neoplasm that affects the inner layer of the pericardium. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEpicardium cancer

Professional guidelines

PubMed

Current clinical management of primary cardiac sarcoma.
Siontis BL, Leja M, Chugh R
Expert Rev Anticancer Ther 2020 Jan;20(1):45-51. Epub 2020 Jan 9 doi: 10.1080/14737140.2020.1711738. PMID: 31914831
Management of neoplastic pericardial disease.
Zhang J, Zhang Q, Chen X, Zhang N
Herz 2020 Dec;45(Suppl 1):46-51. Epub 2019 Jul 11 doi: 10.1007/s00059-019-4833-4. PMID: 31297544
2015 ESC Guidelines for the diagnosis and management of pericardial diseases: The Task Force for the Diagnosis and Management of Pericardial Diseases of the European Society of Cardiology (ESC)Endorsed by: The European Association for Cardio-Thoracic Surgery (EACTS).
Adler Y, Charron P, Imazio M, Badano L, Barón-Esquivias G, Bogaert J, Brucato A, Gueret P, Klingel K, Lionis C, Maisch B, Mayosi B, Pavie A, Ristic AD, Sabaté Tenas M, Seferovic P, Swedberg K, Tomkowski W; ESC Scientific Document Group
Eur Heart J 2015 Nov 7;36(42):2921-2964. Epub 2015 Aug 29 doi: 10.1093/eurheartj/ehv318. PMID: 26320112Free PMC Article

Recent clinical studies

Etiology

Pericardial Mesotheliomas.
Arrossi AV
Adv Anat Pathol 2023 Jul 1;30(4):253-258. Epub 2023 Apr 27 doi: 10.1097/PAP.0000000000000399. PMID: 37104724
Cancer Treatment-Associated Pericardial Disease: Epidemiology, Clinical Presentation, Diagnosis, and Management.
Ala CK, Klein AL, Moslehi JJ
Curr Cardiol Rep 2019 Nov 25;21(12):156. doi: 10.1007/s11886-019-1225-6. PMID: 31768769
Radiation-Associated Pericardial Disease.
Szpakowski N, Desai MY
Curr Cardiol Rep 2019 Jul 27;21(9):97. doi: 10.1007/s11886-019-1192-y. PMID: 31352541
Polyserositis: a diagnostic challenge.
Losada I, González-Moreno J, Roda N, Ventayol L, Borjas Y, Domínguez FJ, Fernández-Baca V, García-Gasalla M, Payeras A
Intern Med J 2018 Aug;48(8):982-987. doi: 10.1111/imj.13966. PMID: 29761620
Congenital Abnormalities of the Pericardium.
Parmar YJ, Shah AB, Poon M, Kronzon I
Cardiol Clin 2017 Nov;35(4):601-614. doi: 10.1016/j.ccl.2017.07.012. PMID: 29025550

Diagnosis

Management of neoplastic pericardial disease.
Zhang J, Zhang Q, Chen X, Zhang N
Herz 2020 Dec;45(Suppl 1):46-51. Epub 2019 Jul 11 doi: 10.1007/s00059-019-4833-4. PMID: 31297544
Cancer Treatment-Associated Pericardial Disease: Epidemiology, Clinical Presentation, Diagnosis, and Management.
Ala CK, Klein AL, Moslehi JJ
Curr Cardiol Rep 2019 Nov 25;21(12):156. doi: 10.1007/s11886-019-1225-6. PMID: 31768769
Imaging of Pericardial Disease.
Kligerman S
Radiol Clin North Am 2019 Jan;57(1):179-199. doi: 10.1016/j.rcl.2018.09.001. PMID: 30454812
Congenital Abnormalities of the Pericardium.
Parmar YJ, Shah AB, Poon M, Kronzon I
Cardiol Clin 2017 Nov;35(4):601-614. doi: 10.1016/j.ccl.2017.07.012. PMID: 29025550
Neoplastic Pericardial Disease.
Maleszewski JJ, Anavekar NS
Cardiol Clin 2017 Nov;35(4):589-600. Epub 2017 Sep 6 doi: 10.1016/j.ccl.2017.07.011. PMID: 29025549

Therapy

Pericardial Involvement in Cancer.
Chahine J, Shekhar S, Mahalwar G, Imazio M, Collier P, Klein A
Am J Cardiol 2021 Apr 15;145:151-159. Epub 2021 Jan 15 doi: 10.1016/j.amjcard.2020.12.092. PMID: 33460602
Cardiovascular Complications of Cancer Therapy: Best Practices in Diagnosis, Prevention, and Management: Part 2.
Chang HM, Okwuosa TM, Scarabelli T, Moudgil R, Yeh ETH
J Am Coll Cardiol 2017 Nov 14;70(20):2552-2565. doi: 10.1016/j.jacc.2017.09.1095. PMID: 29145955Free PMC Article
Radiation-related heart and vascular disease.
Yusuf SW, Howell RM, Gomez D, Pinnix CC, Iliescu CA, Banchs J
Future Oncol 2015;11(14):2067-76. doi: 10.2217/fon.15.129. PMID: 26198837
Malignant mesothelioma.
Kao SC, Reid G, Lee K, Vardy J, Clarke S, van Zandwijk N
Intern Med J 2010 Nov;40(11):742-50. doi: 10.1111/j.1445-5994.2010.02223.x. PMID: 20298508
Mesothelin targeted cancer immunotherapy.
Hassan R, Ho M
Eur J Cancer 2008 Jan;44(1):46-53. Epub 2007 Oct 22 doi: 10.1016/j.ejca.2007.08.028. PMID: 17945478Free PMC Article

Prognosis

Multimodality Imaging for the Assessment of Pericardial Diseases.
Chetrit M, Xu B, Verma BR, Klein AL
Curr Cardiol Rep 2019 Apr 16;21(5):41. doi: 10.1007/s11886-019-1115-y. PMID: 30993456
Under Pressure.
DeFilippis EM, Vaidya A, Ramani S, French C, Kirshenbaum JM
N Engl J Med 2017 Mar 30;376(13):e23. doi: 10.1056/NEJMimc1609719. PMID: 28355512
Primary pericardial tumors.
Restrepo CS, Vargas D, Ocazionez D, Martínez-Jiménez S, Betancourt Cuellar SL, Gutierrez FR
Radiographics 2013 Oct;33(6):1613-30. doi: 10.1148/rg.336135512. PMID: 24108554
Infiltrative cardiomyopathy and pericardial disease.
Yusuf SW, Negi SI, Lenihan DJ
Semin Oncol 2013 Apr;40(2):199-209. doi: 10.1053/j.seminoncol.2013.01.009. PMID: 23540745
Pericardial tumors.
Luk A, Ahn E, Vaideeswar P, Butany JW
Semin Diagn Pathol 2008 Feb;25(1):47-53. doi: 10.1053/j.semdp.2007.12.001. PMID: 18350922

Clinical prediction guides

Fetal thoracic teratomas: mediastinal or pericardial?
Oliver ER, Didier RA, Horii SC, Hedrick HL, Khalek N, DeBari SE, Adzick NS, Coleman BG
Pediatr Radiol 2022 Nov;52(12):2319-2328. Epub 2022 Apr 26 doi: 10.1007/s00247-022-05367-x. PMID: 35471666
Clinical Utility of [(18)F]FDG-PET /CT in Pericardial Disease.
Kim MS, Kim EK, Choi JY, Oh JK, Chang SA
Curr Cardiol Rep 2019 Aug 2;21(9):107. doi: 10.1007/s11886-019-1193-x. PMID: 31376028
Polyserositis: a diagnostic challenge.
Losada I, González-Moreno J, Roda N, Ventayol L, Borjas Y, Domínguez FJ, Fernández-Baca V, García-Gasalla M, Payeras A
Intern Med J 2018 Aug;48(8):982-987. doi: 10.1111/imj.13966. PMID: 29761620
Cardio-oncology/onco-cardiology.
Hong RA, Iimura T, Sumida KN, Eager RM
Clin Cardiol 2010 Dec;33(12):733-7. doi: 10.1002/clc.20823. PMID: 21184556Free PMC Article
Malignant mesothelioma.
Kao SC, Reid G, Lee K, Vardy J, Clarke S, van Zandwijk N
Intern Med J 2010 Nov;40(11):742-50. doi: 10.1111/j.1445-5994.2010.02223.x. PMID: 20298508

Recent systematic reviews

A Systematic Review and Meta-Analysis of Prevalence and Outcomes of Cardiac Metastasis of Neuroendocrine Malignancies.
Hamza M, Manasrah N, Patel NN, Sattar Y, Patel B
Am J Cardiol 2023 May 1;194:86-92. Epub 2023 Mar 29 doi: 10.1016/j.amjcard.2023.02.011. PMID: 36996525
PD-1/L1 inhibitors may increase the risk of pericardial disease in non-small-cell lung cancer patients: a meta-analysis and systematic review.
Li H, Han D, Zhang L, Feng X, Li H, Yang F, Song L, Li X
Immunotherapy 2022 May;14(7):577-592. Epub 2022 Apr 4 doi: 10.2217/imt-2021-0223. PMID: 35373580
Extramedullary disease in multiple myeloma: a systematic literature review.
Bladé J, Beksac M, Caers J, Jurczyszyn A, von Lilienfeld-Toal M, Moreau P, Rasche L, Rosiñol L, Usmani SZ, Zamagni E, Richardson P
Blood Cancer J 2022 Mar 21;12(3):45. doi: 10.1038/s41408-022-00643-3. PMID: 35314675Free PMC Article
Interventions for treating tuberculous pericarditis.
Wiysonge CS, Ntsekhe M, Thabane L, Volmink J, Majombozi D, Gumedze F, Pandie S, Mayosi BM
Cochrane Database Syst Rev 2017 Sep 13;9(9):CD000526. doi: 10.1002/14651858.CD000526.pub2. PMID: 28902412Free PMC Article
Epidemiology of mesothelioma of the pericardium and tunica vaginalis testis.
Mezei G, Chang ET, Mowat FS, Moolgavkar SH
Ann Epidemiol 2017 May;27(5):348-359.e11. Epub 2017 Apr 14 doi: 10.1016/j.annepidem.2017.04.001. PMID: 28527639

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